• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2711-2717
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• 2016

Background: Through search the possible randomized control trials, we make a renewed meta-analysis in order to assess the impact of aspirin in preventing the recurrence of colorectal adenoma. Materials and Methods: The Medicine/PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Chinese biomedical literature service system (SinoMed) databases were searched for the related randomized controlled trials until to the April 2016. Three different authors respectively evaluated the quality of studies and extracted data, and we used the STATA software to analyze, investigate heterogeneity between the data, using the fixed-effects model to calculate and merge data. Results: 7 papers were included the renewed meta-analysis, among these studies, two pairs were identified as representing the same study population, with the only difference being the duration of follow-up. Thus there were only five papers included our meta-analysis, and one Chinese paper were also included the work. Results were categorized by the length of follow-up, different kinds of people, varied dose of oral aspirin. The relative of adenoma in patients taking aspirin vs placebo were 0.73 (95% CI 0.55-0.98, P=0.039) with 1 year follow up; 0.84 (95% CI 0.72-0.98, P=0.484) with greater than 1 year follow up; for the advanced adenoma, the RR 0.68 (95% CI 0.49-0.94, P=0.582),for one year; RR=0.75 (95% CI 0.52-1.07, P=0.552) for greater one year. Furthermore the white population could divided into two subgroups according to the different length of follow-up time. When the length of follow-up time less than 3-year, The RR of two subgroups respective were RR=0.86 (95% CI 0.76-0.98, P=0.332), $I^2=0%$, RR=0.68 (95% CI 0.47-0.98, P=0.552), $I^2=64.6%$, But with the extension of follow-up time greater than 2-year, with the white, oral aspirin without considering dose had no efficacy on preventing the recurrence of any adenoma, the RR was 0.86 (95% CI 0.71-1.05, P=0.302), $I^2=16.4%$. Conclusions: This meta-analysis indicated that oral aspirin is associated with a remarkable decrease in the recurrence of any adenoma and advanced adenomas in patients follow-up for 1 year without concerning the dose of aspirin, but with the extension of follow-up time for greater than 1 year, oral aspirin can be effective on preventing the recurrence of any adenoma, but for the advanced adenoma, the result indicated that oral aspirin had no efficacy, According to the inclusion of ethnic groups, we also divided relevant papers into two subgroups as the yellow and white group. Then the follow-up time was less than 3 years, oral aspirin without considering the dose, had an significant efficacy on preventing the recurrence of any adenoma. But with the follow-up greater than 2 years, oral aspirin had no effect in the white.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2507-2513
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• 2015

Background: Serum vitamin D status can affect the prognosis of breast cancer patients. Our aim was to determine the association between alterations in the 25-hydroxyvitamin D [25(OH)D] status during follow-up and the prognosis of breast cancer patients. Additionally, we evaluated the association between the 25(OH)D status at the time of diagnosis and the prognosis using a detailed age and stage categorization. Materials and Methods: Four hundred and sixty-nine Korean breast cancer patients were included. We collected patient clinicopathological data, including their serum 25(OH)D concentration at diagnosis and at the annual follow-up until 4 years after diagnosis. The patients were divided according to their 25(OH)D status at diagnosis into a deficient (<20 ng/ml) and a non-deficient (${\geq}20ng/ml$) group. At follow-up, patients were categorized into the four following groups according to 25(OH)D status alterations: persistently deficient, improved, deteriorated and persistently non-deficient. Results: At diagnosis, 118 patients were classified into the deficient group and 351 into the non-deficient group. After a median follow-up period of $85.8{\pm}31.0$ months, the patients with advanced-stage disease or an older age in the non-deficient group showed a significantly better survival compared with the deficient group. Furthermore, at the 1-year follow-up of 25(OH)D status, the persistently non-deficient group and the improved group had better survival compared with the other two groups. Conclusions: Our results suggest that maintaining an optimal 25(OH)D status at diagnosis and during the 1-year follow-up period is important for improving breast cancer patient survival.

• 대한족부족관절학회지
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• 제21권3호
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• pp.93-97
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• 2017

Purpose: The aim of this study was to evaluate the radiological and clinical outcomes of scarf osteotomy for hallux valgus (HV) deformity in elderly patient with osteoporosis. Materials and Methods: A total of 58 elderly patients (mean age, 72.6 years) underwent scarf osteotomy for HV deformity between 2008 and 2015. The mean follow-up period was 24.4 months. Of the 58 patients, 42 were diagnosed with osteoporosis and 16 were diagnosed as normal. The radiological and clinical outcomes were assessed preoperatively, postoperatively, and at final follow-up, including HV angle, intermetatarsal (IM) angle, American Orthopaedic Foot and Ankle Society (AOFAS) score, patient satisfaction, visual analogue scale (VAS), and complication. Results: There was no significant difference in HV angle and IM angle between the osteoporosis group and normal bone mineral densitometry group at all time points, preoperative, postoperative, and final follow-up. Moreover, there was no statistically significant difference between the two groups with respect to the AOFAS score and VAS evaluations. In the osteoporosis group, the mean HV angle improved from $36.7^{\circ}$ preoperatively to $11.3^{\circ}$ at the time of final follow-up, and the mean IM angle improved from $13.2^{\circ}$ to $5.7^{\circ}$. The mean AOFAS score improved from 52.6 preoperatively to 89.1 at the time of final follow-up. With respect to satisfaction, 83.4% of patients were very satisfied or satisfied. There were no serious complications, and all cases showed complete union at the osteotomy site. Conclusion: We believed that scarf osteotomy is a safe, effective procedure for the correction of elderly patients with osteoporosis.

• Tuberculosis and Respiratory Diseases
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• 제81권1호
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• pp.49-58
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• 2018

Background: Information regarding the incidence and risk factors for deep vein thrombosis (DVT) detected by follow-up computed tomographic (CT) venography after pulmonary embolism (PE) is sparse. The aim of the present study was to identify the predictors of DVT in follow-up CT images, and to elucidate their clinical significance. Methods: Patients with PE were classified into the following three cohorts based on the time of indirect CT venography follow-up: within 1 month, 1 to 3 months, and 3 to 9 months after the initial CT scan. Each cohort was subdivided into patients with or without DVT detected by follow-up CT. Clinical variables were compared between the two groups. Results: Follow-up CT revealed DVT in 61% of patients with PE within 1 month, in 15% of patients with PE at 1 to 3 months, and in 9% of patients with PE at 3 to 9 months after the initial CT scan. Right ventricular (RV) dilation on the initial CT (odds ratio [OR], 8.30; 95% confidence interval [CI], 1.89-36.40; p=0.005) and proximal DVT at the initial presentation (OR, 6.93; 95% CI, 1.90-25.20; p=0.003) were found to independently predict DVT in follow-up CT images within 1 month, proximal DVT at the initial presentation was found to independently predict DVT in follow-up CT images at 1 to 3 months (OR, 6.69; 95% CI, 1.53-29.23; p=0.012), and central PE was found to independently predict DVT in follow-up CT images at 3 to 9 months (OR, 4.25; 95% CI, 1.22-4.83; p=0.023) after the initial CT scan. Furthermore, the detection of DVT by follow-up CT independently predicted the recurrence of venous thromboembolism (VTE) (OR, 4.67; 95% CI, 2.24-9.74; p<0.001). Conclusion: Three months after PE, DVT was not detected by follow-up CT in most patients with PE. RV dilation on the initial CT, central PE, and proximal DVT at the initial presentation were found to predict DVT on follow-up CT, which might predict VTE recurrence.

• 대한가정학회지
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• 제41권7호
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• pp.169-184
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• 2003

This study examined a causal relation between employment and depression among low-income young mothers who participated in New Chance Demonstration Study(NC). Using baseline and first follow-up interview data from NC study, this study selected 756 young mothers who were at risk of depression and unemployed at baseline. About 18% of them were employed and 45% of them were no longer at risk of depression at the first follow-up interview. The young mothers grade level and their race/ethnicity were significantly related to the number of weeks employed between the two time points and employment at the 1st follow-up interview. It was also found that employment was negatively associated with depression at the 1st follow-up interview. These findings imply that employment can ameliorate depressive symptoms of low-income young mothers.

• 천문학회보
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• 제41권1호
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• pp.61.1-61.1
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• 2016

As a new way to explore the universe, astronomers are now performing time-domain astronomy by surveying the universe looking for new transient phenomena and taking movies of the universe with telescopes. Large-area, time-series survey of astronomical objects are uncovering many interesting, fast-changing objects that have now been poorly understood before, such as GRBs, tidal disruption phenomena, and new types of supernova. In order to characterize these new, exciting events, it is very critical to perform follow-up observations, and 1-2m telescopes can effectively contribute to such efforts. Since 2007, our group has been performing follow-up observations of gamma-ray bursts (GRBs) and interesting transients using BOAO and other KASI facilities. Here, we present results from several key transient studies that were done by using BOAO: (1) tidal disruption event Swift J1644+57; (2) SN 2011fe that occurred in M101; and (3) several GRB events. These study demonstrates the usefulness of BOAO as a powerful transient follow-up facility. Finally, we will discuss how BOAO research activities can possibly be bolstered in this newly emerging field of astronomy.

• Hip & pelvis
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• 제35권1호
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• pp.40-46
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• 2023

Purpose: A variety of short Exeter stems designed specifically for use in performance of total hip arthroplasty (THA) in primary and revision settings have recently been introduced. Some have been used 'off label' for hip reconstruction. The aim of this study is to report clinical and radiological results from the Exeter V40 125 mm stem in performance of primary THA and revision THA. Materials and Methods: This study had a retrospective design. Insertion of 58 (24 primary, 34 revision) Exeter V40 125 mm stems was performed between 2015 and 2017. The minimum follow-up period was two years. Assessment of the Oxford hip score (OHS), EuroQol-5 Dimension (EQ-5D), and radiological follow-up was performed at one and two years. Results: In the primary group, the preoperative, mean OHS was 13.29. The mean OHS was 32.86 and 23.39 at one-year and two-year post-surgery, respectively. The mean EQ-5D-3L scores were at 0.14, 0.59, and 0.35, preoperatively, at one-year follow-up and two-year follow-up, respectively. In the revision group, the mean preoperative OHS was 19.41. The mean OHS was 30.55 and 26.05 at one-year and two-year post-surgery, respectively. The mean EQ-5D-3L scores were 0.33, 0.61, and 0.48 preoperatively, at one-year follow-up and two-year follow-up, respectively. No progressive or new radiolucent lines were observed around any stem at the time of the final follow-up in all patients in both groups. Conclusion: Encouraging results regarding use of Exeter V40 125 mm stems have been reported up to two years following surgery in primary and revision THA settings.

• Journal of Chest Surgery
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• 제15권1호
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• pp.53-60
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• 1982

M-mode echocardiographic studies of left ventricular function in mitral valve disease were evaluated in 19 surgically treated patients before and one year after operation (mean 12.7 months). Twelve patients had mitral stenosis (MS) and seven patients had mitral regurgitation (MR). Before surgery, average end-diastolic and end systolic dimensions (EDD, and ESD) and left atrial dimension were significantly greater than normal in subject with MR. After surgery, EDD fell significantly from $66.5{\pm}8.4$ (SD)mm to $52.7{\pm}6.3$mm (P 0.01) at the time of late follow up study; ESD fell significantly from $46.5{\pm}9.7$mm to $36.4{\pm}8.6$ (P 0.05) on early follow up study; left atrial dimension fell significantly from $60.5{\pm}6.8$mm to $48.1{\pm}7.2$mm (P 0.01) at the time of the late follow up study. In patients with MS, EDD and ESD were normal and did not change significantly at any time after surgery. The left ventricular ejection fraction (E.F.) was normal in both groups. preoperatively([MR: $64.2{\pm}15.1$, MS: $65.7{\pm}12.3$). After surgery, E.F. did not change significantly at any time after surgery in both groups, but de-creased from $64.2{\pm}15.1$% to $59.5{\pm}11.2$% in MR patients at the time of early follow up study.

• The Journal of Advanced Prosthodontics
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• 제14권3호
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• pp.133-142
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• 2022

PURPOSE. A large number of studies have suggested the practicability and predictability of immediate implant function, but few studies have reported marginal bone level changes during sequential loading periods. The purpose of this study was to evaluate the marginal bone remodeling of immediately loaded self-tapping implants both at each time point and during each loading period between two time points. MATERIALS AND METHODS. The patients included in this retrospective study were treated with immediately loaded NobelSpeedy Replace implants between August 2008 and July 2009. Differences in the marginal bone level (MBL) at each time point and the marginal bone level change (ΔMBL) between two time points were analyzed with Bonferroni correction (P < .05). RESULTS. Overall, 24 patients (mean age, 47.3 ± 12.8 years) with 42 immediately loaded implants and a median follow-up of 6.5 years (IQR, 67.8 months) were included. The cumulative survival rate after 10 - 12 years was 95.2%. Continuous but slow marginal bone loss was observed during long-term follow-up. MBL at both 7.5 years and 11 years was significantly lower than that at loading, 6 months, 2 years and 4 years (P < .05). No bone loss difference was found in any period before 4 years of follow up (P > .05). The loading period of 4 years to 7.5 years showed the largest ΔMBL compared to those of other time periods (P < .05). CONCLUSION. Slight bone loss occurred continuously, and more radical changes of marginal bone can be observed during the period of 4-7.5 years. Thus, long-term effective follow-up of immediately loaded implants is needed.

• 지역사회간호학회지
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• 제4권1호
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• pp.45-57
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• 1993

The study was conducted with 27 health mangers working in manufacturing industries. The purpose of this study was to analyze the health manager's employment status, health examination, and it's follow. up health management level(about the industrial type). The results are as follows: 1. Characteristics of Manufacturing Industries: The ratio of nurse to employees is 1 : 552.6 and the percentage of physician employed was 51.9% All of the physicians were part time except one. 2. Health Examination and Follow Up ; 1) Periodic screening examinations were provided to 92.39% of the employees. Of these 11.56% required a detailed examination. Follow up on routine cases were done for 51.69%. Follow up on intensive cases were done 13.97%. 2) 62% of all employees working in hazardous conditions(noise, artificial light 74.1%) are required to receive a special health examination bi annually. Of these 96.66% were examined. 11.24% of these employees required a detailed follow up examination. 3. Relevancy between health management level, industrial type, and health manager's status 1) Health clinic operated separately except one case. Nursing activity level :. health diagnosis(0.27) Occupational condition (0.97) Health education(0.81) Health assessment(0.74) Health education level is higher at the industries working in environmental technician(P=0.017). The other's significance is not shown by any type of the staff.