• Title/Summary/Keyword: Flux Analysis

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Accurate Metabolic Flux Analysis through Data Reconciliation of Isotope Balance-Based Data

  • Kim Tae-Yong;Lee Sang-Yup
    • Journal of Microbiology and Biotechnology
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    • v.16 no.7
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    • pp.1139-1143
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    • 2006
  • Various techniques and strategies have been developed for the identification of intracellular metabolic conditions, and among them, isotope balance-based flux analysis with gas chromatography/mass spectrometry (GC/ MS) has recently become popular. Even though isotope balance-based flux analysis allows a more accurate estimation of intracellular fluxes, its application has been restricted to relatively small metabolic systems because of the limited number of measurable metabolites. In this paper, a strategy for incorporating isotope balance-based flux data obtained for a small network into metabolic flux analysis was examined as a feasible alternative allowing more accurate quantification of intracellular flux distribution in a large metabolic system. To impose GC/MS based data into a large metabolic network and obtain optimum flux distribution profile, data reconciliation procedure was applied. As a result, metabolic flux values of 308 intracellular reactions could be estimated from 29 GC/ MS based fluxes with higher accuracy.

A Study on the Analysis of Surface Heat Flux Using the Transient Heat Flux Method (비정상열유속 기법을 이용한 표면 열유속 해석에 관한 연구)

  • Yi, Jong-Ju
    • Journal of the Korea Institute of Military Science and Technology
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    • v.13 no.3
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    • pp.503-510
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    • 2010
  • The quick variation of the canister wall temperature causes the modification of the shape of canister wall. This paper is the possibility of adoption and the error analysis about the transient heat flux method. The commercial code(Fluent Ver6.2.16) was employed for the calculation of surface temperature in the case of steady and unsteady heat flux condition. Based the surface temperature variation and surface material property, transient heat flux method can calculate the surface heat flux. In the case of steady heat flux condition, the error is about 2%, and in the case of unsteady heat flux condition, the error is about 3.6%. With the unsteady heat flux condition, the time which reach the maximum surface heat flux is almost same between the numerical analysis and transient heat flux method.

Systems-Level Analysis of Genome-Scale In Silico Metabolic Models Using MetaFluxNet

  • Lee, Sang-Yup;Woo, Han-Min;Lee, Dong-Yup;Choi, Hyun-Seok;Kim, Tae-Yong;Yun, Hong-Seok
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.10 no.5
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    • pp.425-431
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    • 2005
  • The systems-level analysis of microbes with myriad of heterologous data generated by omics technologies has been applied to improve our understanding of cellular function and physiology and consequently to enhance production of various bioproducts. At the heart of this revolution resides in silico genome-scale metabolic model, In order to fully exploit the power of genome-scale model, a systematic approach employing user-friendly software is required. Metabolic flux analysis of genome-scale metabolic network is becoming widely employed to quantify the flux distribution and validate model-driven hypotheses. Here we describe the development of an upgraded MetaFluxNet which allows (1) construction of metabolic models connected to metabolic databases, (2) calculation of fluxes by metabolic flux analysis, (3) comparative flux analysis with flux-profile visualization, (4) the use of metabolic flux analysis markup language to enable models to be exchanged efficiently, and (5) the exporting of data from constraints-based flux analysis into various formats. MetaFluxNet also allows cellular physiology to be predicted and strategies for strain improvement to be developed from genome-based information on flux distributions. This integrated software environment promises to enhance our understanding on metabolic network at a whole organism level and to establish novel strategies for improving the properties of organisms for various biotechnological applications.

Design of Linear Transverse Flux Machine for Stelzer Machine using Equivalent Magnet Circuit and FEM

  • Jeong, Sung-In
    • Journal of Electrical Engineering and Technology
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    • v.13 no.4
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    • pp.1596-1603
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    • 2018
  • This paper presents the new design and validation process of the linear transverse flux machine of the stelzer machine for hybrid vehicle application. A linear transverse flux machine is a novel electric machine that has higher force density and power than conventional electric machine. The process concentrates on 2-dimensional and 3-dimensional analysis using equivalent magnetic circuit method considering leakage elements and it is verified by finite element analysis. Besides the force characteristics of all axis of each direction are analyzed. The study is considered by dividing the transverse flux electric excited type and the transverse flux permanent magnet excited type. Additionally three-dimensional analysis in this machine is accomplished due to asymmetric structure with another three axes. Finally, it suggests the new design and validation process of linear transverse flux machine for stelzer machine.

Sensitivity Study of the Flow-through Dynamic Flux Chamber Technique for the Soil NO Emissions

  • Kim Deug-Soo
    • Journal of Korean Society for Atmospheric Environment
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    • v.21 no.E3
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    • pp.75-85
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    • 2005
  • A mathematical sensitivity analysis of the flow-through dynamic flux chamber technique, which has been utilized usually for various trace gas flux measurement from soil and water surface, was performed in an effort to provide physical and mathematical understandings of parameters essential for the NO flux calculation. The mass balance equation including chemical reactions was analytically solved for the soil NO flux under the steady state condition. The equilibrium concentration inside the chamber, $C_{eq}$, was found to be determined mainly by the balance between the soil flux and dilution of the gas concentration inside the chamber by introducing the ambient air. Surface deposition NO occurs inside the chamber when the $C_{eq}$ is greater than the ambient NO concentration ($C_{0}$) introducing to the chamber; NO emission from the soil occurs when the $C_{eq}$ is less than the ambient NO concentration. A sensitivity analysis of the significance of the chemical reactions of NO with the reactive species (i.e. $HO_{2},/CH_{3}O_{2},/O_{3}$) on the NO flux from soils was performed. The result of the analysis suggests that the NO flux calculated in the absence of chemical reactions and wall loss could be in error ranges from 40 to $85\%$ to the total flux.

A Study on Sinewave Air Gap Flux Density of Surface Type Magnet Motor (표면부착형 영구자석 전동기의 정현파 공극자속밀도 연구)

  • Kim, Hyun-Cheol;Kim, Jang-Mok;Kim, Cheul-U
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.9
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    • pp.1571-1576
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    • 2007
  • This report describes the analytical characteristic of sinewave air gap flux density for the brushless AC motor with surface permanent magnet. The analysis of sinewave air gap flux density is the key to expect the performance of back EMF for the design of brushless AC motor. The numerical analysis and FEM analysis are performed to adopt radial and parallel flux magnetization of magnet on the rotor. And it is also executed to vary the magnet arc angle and arc radius for the condition of constant and non constant air gap. This report is focused on the characteristic of sinewave air gap flux density for permanent magnet of surface brushless AC motor. This results also have more reliable data against the previous paper which had the representative numerical analysis of air gap flux density[1][2].

Characteristic Analysis of a Permanent Magnet Transverse Flux Linear Motor with Spiral Core

  • Lee, Ji-Young;Kim, Ji-Won;Woo, Byung-Chul;Kang, Do-Hyun
    • Journal of Magnetics
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    • v.18 no.2
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    • pp.111-116
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    • 2013
  • This paper presents a characteristic analysis method of a permanent magnet type transverse flux linear motor (TFLM) with spiral cores. The spiral cores are used as the mover cores in order to make 3-dimensional (3-D) magnetic flux paths at the TFLM which have 3-D magnetic flux flows. The 3-D Equivalent Magnetic Circuit Network Method is used to analyse the magnetic characteristics of the machine, and an imaginary part, 'flux barrier,' is introduced to consider the spiral core characteristic. Magnetic parameters such as flux, inductance, and thrust are calculated from the analysis results. The computed thrust forces are compared to measured values to confirm the accuracy of the analysis.

A Study on Back EMF of BLDC Motor Using Numetical Analysis Method (수치해석 방법을적용한 BLDC 전동기의 역기전력 연구)

  • Kim, Hyun-Cheol
    • Journal of the Korean Society of Safety
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    • v.23 no.4
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    • pp.36-41
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    • 2008
  • This report describes the analytical solution of back EMF for BLDC motor using numerical analysis of air gap flux density. The analysis of air gap flux density is the key to expect the performance of back EMF for the design of brushless motor. The numerical analysis and FEM analysis are performed to vary attachment of stator side or rotor side, radial flux magnetization or parallel flux magnetization, magnet arc angle in the condition of constant air gap. This results have more reliable data comparing with test result of the back EMF for 7 phase BLDC motor.

접착형 박막 측온게이지식 열류센서의 개발에 관한 연구

  • 한응교;박두원;최규철;노병옥;이명호
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1991.11a
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    • pp.80-86
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    • 1991
  • In this study an the development of the heat flux sensor with thermocouple, the heat-treated adhesive type film nickel gauge(Ni-Gauge) for measuring temperature was used. and this Ni-Gauge is not only comparable for platinum gauge(Pt-Gauge) in linearity, but also economically cheap. And from this viewpoint. numerical analysis is essential to investigate charateristics of sensor, since this analysis is capable of simulating precise boudary condition and practical conditions and so on. By the way. there are many types of heat flux sensor. of which adhesive type flux sensor is common, in the study this type of heat flux sensor was chogen. and analysis of the sensor is considered as a kind of open cavity figure. performed by SIMPLER algorithm. As a result. through temperature distributial of the sensor by numerical analysis in steady and unsteady state, the dracteristics of the acdhesive type heat flux sensor(lst heat flux sensor) acooodinge to heat flux, that is, outvoltage, sensitivity. and responsibilty could be evaluated. in addition, time of improved heat flux sensor(2nd heat flux sensor) could be predicted fran the reflectian of proper operating temperature(l50 $^{\circ}C$)of theNi-Gauge.

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Dynamic Characteristic Analysis of Rotating Type Axial Phase Permanent Magnet Transverse Flux Machine (축방향 2상 영구자석형 횡자속 회전기의 동특성 해석)

  • Lee, Ji-Young;Lee, In-Jae;Kang, Do-Hyun;Chang, Jung-Hwan;Kim, Ji-Won;Chung, Si-Uk
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1029-1030
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    • 2007
  • This paper describes the dynamic analysis method and the characteristics of rotating type transverse flux motors excited by permanent magnets; the machine is called TFRM in here. A prototype of TFRM, made by combing soft magnetic composite (SMC) core, is introduced first, then the magneto static and dynamic analysis methods are explained. Analysis results are compared with measured results, and finally the effects of the proposed dynamic analysis method and the characteristics of TFRM are discussed.

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