• 한국해양공학회지
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• 제36권6호
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• pp.380-389
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• 2022

In the Haeundae area of Busan, South Korea, damage has continued to occur recently from building wind from caused by dense skyscrapers. Five wind observation stations were installed near LCT residential towers in Haeundae to analyze the effect of building winds during typhoon Omais. The impact of building wind was analyzed through relative and absolute evaluations. At an intersection located southeast of LCT (L-2), the strongest wind speed was measured during the monitoring. The maximum average wind speed for one minute was observed to be 38.93 m/s, which is about three times stronger than at an ocean observation buoy (12.7 m/s) at the same time. It is expected that 3 to 4 times stronger wind can be induced under certain conditions compared to the surrounding areas due to the building wind effect. In a Beaufort wind scale analysis, the wind speed at an ocean observatory was mostly distributed at Beaufort number 4, and the maximum was 8. At L-2, more than 50% of the wind speed exceeded Beaufort number 4, and numbers up to 12 were observed. However, since actual measurement has a limitation in analyzing the entire range, cross-validation with computational fluid dynamics simulation data is required to understand the characteristics of building winds.

• Journal of Korean Neurosurgical Society
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• 제66권1호
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• pp.82-89
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• 2023

Objective : Rathke's cleft cysts (RCCs) are nonneoplastic cysts. Most of them are asymptomatic and stable; when symptomatic, RCCs are surgically fenestrated and drained. However, the outcomes remain unclear. The authors evaluated the outcomes of RCC decompression. Methods : Between 2004 and 2019, 32 RCCs were decompressed in a single tertiary institution. The clinical characteristics, intraoperative findings, postoperative complications, and endocrinological and surgical outcomes were retrospectively reviewed. Patients who underwent sequential imaging at least twice and at least 12 months after surgery were included in the analysis. Results : Patients' mean age was 40.8±14.9 years, and 62.5% were women. The mean follow-up duration was 62.3±48.6 months. In 21 patients (65.6%), no residual cysts were identified on postoperative magnetic resonance imaging. Of the 18 patients with preoperative visual field defects, 17 (94.4%) experienced postoperative visual improvement. Postoperative complications included endocrinological deterioration in 11 patients (34.4%), permanent diabetes insipidus in 11 (34.4%), infection in four (12.5%), intrasellar hemorrhage in three (9.4%), and cerebrospinal fluid leak in two (6.3%). Follow-up images revealed cyst recurrence in nine patients (28.1%), an average of 20.4 months after surgery; in three patients, the cysts were symptomatic, and resection was repeated. Multivariable analysis revealed that postoperative endocrinological deterioration was the only independent factor associated with cyst recurrence (p=0.028; hazard ratio, 6.800). Conclusion : Our findings showed that although only cyst fenestration for decompression was performed to preserve pituitary function, more pituitary dysfunction occurred than expected. Besides, the postoperative hormonal deterioration itself acted as a risk factor for cyst recurrence. In conclusion, surgery for RCC should be more careful.

• 한국임상수의학회지
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• 제40권1호
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• pp.56-61
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• 2023

A 5-month-old female domestic short-haired cat presented with a history of seizure episodes for two months following an animal bite injury to the head. There were no remarkable findings on physical and neurological examination or blood analysis. Computed tomography revealed a fracture of the left parietal bone with an inward displacement of the bone fragment while magnetic resonance imaging revealed an enlarged temporal horn of the left lateral ventricle and a pseudomeningocele compressing the adjacent cerebral parenchyma. Subsequently, cerebrospinal fluid analysis results were normal. The patient was diagnosed with traumatic brain injury (TBI), with subsequent post-traumatic hydrocephalus (PTH) and pseudomeningocele. Despite treatment with phenobarbital and levetiracetam, seizures were not sufficiently controlled. Craniectomy for bone fragment removal and duraplasty were performed after a week. The patient then returned to normal condition with no further seizure activity. On repeated MRI two months after discharge, the hydrocephalus of the lateral ventricle and pseudomeningocele were enlarged; however, the patient maintained a good clinical status without any neurological signs. To the best of our knowledge, PTH and intracranial pseudomeningoceles have not yet been reported in cats. PTH and pseudomeningocele are among the complications of TBI and may not have any significant relevance with the clinical signs in this case. Thus, to broaden our knowledge about PTH and pseudomeningocele in cats, we describe serial changes in the clinical findings of this cat over the treatment period.

• Journal of Korean Neurosurgical Society
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• 제65권3호
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• pp.457-468
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• 2022

Objective : The clinical management paradigm of skull base chordomas is still challenging. Surgical resection plays an important role of affecting the prognosis. Endonasal endoscopic approach (EEA) has gradually become the preferred surgical approach in most cases, but traditional transcranial surgery cannot be completely replaced. This study presents a comparison of the results of the two surgical strategies and a summary of the treatment algorithms for skull base chordomas. Methods : We retrospectively analyzed the surgical outcomes and follow-up data of 48 patients with skull base chordomas diagnosed pathologically who received transnasal midline approaches (TMA) and transcranial lateral approaches (TLA) from 2010 to 2020. Results : Among the 48 patients, 36 cases were adopted TMA and 12 cases were performed with TLA. In terms of gross total resection (GTR) rate, 27.8% in TMA and 16.7% in TLA and with EEA alone it was increased to 38.9%, while 29.7% in primary surgery. In TMA, the cerebrospinal fluid (CSF) leak remains the most common complication (13 cases, 36.1%), other main complications included death, cranial nerve palsy, hypopituitarism, all the comparisons were no statistical significance. The Karnofsky Performance Scale scores in TMA were all better than those in TLA at different time, and the overall survival (OS) and recurrence free survival/progression free survival was just the reverse. Conclusion : The EEA for skull base chordomas resection has improved the GTR rate, but transcranial approach is still an alternative approach. It is necessary to select an appropriate surgical approach based on the location and the pattern of tumor growth in order to obtain the best surgical outcomes.

• Journal of Korean Neurosurgical Society
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• 제65권3호
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• pp.479-488
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• 2022

Objective : The surgical management of trigeminal neuralgia (TN) caused by petrous apex meningioma (PAM) is still a challenge because of the lesion's deep location and the surrounding complex structures. The authors describe the intradural anterior transpetrosal approach (ATPA) and its effect on the treatment of TN secondary to PAM. Methods : A retrospective analysis of 15 patients with TN secondary to PAM who underwent surgery via the intradural ATPA was conducted. The key techniques, which included drilling off the petrosal apex (PA) and opening the upper wall of Meckel's cave (MC), are described in detail. Results : Total removal of the tumor and complete pain relief (Barrow Neurological Institute I) were achieved in all 15 patients without significant morbidity. Five patients developed new facial numbness postoperatively, which disappeared within three months after surgery. The postoperative magnetic resonance imaging showed temporal lobe swelling in three patients, but no clinical symptoms. One patient had cerebrospinal fluid leakage and was managed with bed rest and temporary lumbar drainage. One patient had an intracranial infection and was treated with antibiotics. By the last follow up, no patients had pain relapse or/and tumor recurrence. It is worth noting that the vascular compression at the root of the trigeminal nerve was found in one patient during the operation. Conclusion : Our experience suggests that drilling off the PA and opening the upper wall of the MC are key elements for a good outcome of the treatment of TN secondary to PAM. The intradural ATPA has the advantages for both tumor resection and pain relief.

• 현장농수산연구지
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• 제20권2호
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• pp.117-123
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• 2018

본 연구의 목적은 성숙한 당나귀의 큰잘록 창자 폐색 증례를 진단하여 보고하고자 한다. 당나귀(Equus africanus asinus; 암, 6세) 1마리가 제주경마공원 동물병원에 전날부터 시작된 식욕부진 증상으로 내원하였다. 장음소실, 탈수, 심한 복강 확장 등의 증상을 확인하였으나 호흡수 및 심박수는 정상이었고, 복통 증상은 없었다. 직장검사에서 폐색된 부분이 잘록 창자임을 확인하였다. 위세척, 수액요법 및 비스테로이드 계열의 진통제를 투여하였으나 다음날 새벽 갑자기 몸을 떨며 기립곤란과 같이 신체상태가 악화되기 시작한지 2시간 만에 폐사하였다. 부검에서 특히 왼배쪽 잘록 창자와 같은 큰잘록 창자에서 다량의 식괴를 발견하였고, 막창자와 곧창자는 정상이었다. 당나귀는 내원하기 11일 전에 새로 입사해서 사양 관리체계가 바뀌었다. 사료변경, 수분섭취 감소, 운동부족 등이 질병을 유발하였을 것으로 생각된다. 그러나 당나귀의 정확한 급사원인은 더 연구해야 할 과제로 남는다.

• 한국임상수의학회지
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• 제28권4호
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• pp.438-441
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• 2011

7연령의 중성화된 수컷, 단모종 고양이가 2년 동안 지속된 만성 비루와 재채기를 주증상으로 내원 하였다. 내원 당시 양측 비강내 화농성 비루가 관찰되었으며, 신체검사상 빈호흡이 확인되었다. 구강 및 흉강 방사선 검사는 정상이었으며, 두경부의 방사선 검사에서 비강과 고포의 이상이 발견되었다. 비강내 세포학 검사결과는 진단에 특이적인 소견을 제시하지 못했다. 확진을 위하여 추가적으로 컴퓨터 단층촬영검사, 비강과 비인두의 내시경 및 조직 검사가 실시 되었다. 컴퓨터 단층촬영을 통하여 양측 비강 및 비인두, 우측 고실내의 액체/연부조직 음영이 확인되었으며, 병변부의 종양성 변화는 확인되지 않았다. 비강경 및 검이경 검사를 통하여 병변부를 육안적으로 확인 할 수 있었다. 환축은 조직검사를 통하여, 림포형질세포성 비염으로 진단되었으며, cyclosporine을 이용하여 효과적으로 관리 되었다. 결론적으로 본 증례의 경우 고양이에서 발생한 림포형질세포성 비염의 임상증상과 진단, 그리고 cyclosporine을 이용한 치료 반응에 대한 국내 첫 증례보고이다.

• Journal of Korean Neurosurgical Society
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• 제30권5호
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• pp.575-580
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• 2001

Purpose : In general, pineal region tumors are managed by using microsurgical approach or stereoctactic biopsy. However, in selected cases endoscopic approach to pineal lesions might prove to be as effective as microsurgery and less invasive. We report an alternative surgical strategy for managing certain patients with pineal neoplasms that allows treatment of the symptomatic hydrocephalus as well as tumor biopsy under direct vision in the same sitting. Materials and Methods : Twenty-two patients with pineal region tumors with associated hydrocephalus were treated in one session by endoscopic third ventriculostomy and endoscopic tumor biopsy at our institution from October 1996 to January 2000. All patients were retrospectively evaluated. Results : There was no operative mortality. There was one cause of significant bleeding during biopsy, but was controlled endoscopically, and the patient recovered completely without neurologic deficit resulting from intra-operative bleeding. The symptoms related to increased intracranial pressure(ICP) have resolved in all patients, and the need for a shunt is completely eliminated. Histological diagnosis was achieved in 21 of the 22 patients by this procedure. A biopsy was not obtained in one patient. Although this pineal region tumor was seen endoscopically, this could not be biopsied because of technical difficulties in working around an enlarged massa intermedia. The lesions included fourteen germinomas, three mixed germ cell tumors, and one each of the followings: pineocytoma, pineoblastoma, pineocytoma/pineoblastoma(intermediate type), meningioma, and low grade glioma. Five of the 22 patients subsequently underwent formal microsurgical tumor removal. Additional chemotherapy or radiotherapy could then be initiated according to the histological diagnosis. Conclusion : We consider that endoscopy affords a minimally invasive way of reaching three objectives by one-step surgery in the management of pineal region tumors with associated hydrocephalus : 1) cerebrospinal fluid(CSF) sample for analysis of tumour markers and cytology, 2) treatment of hydrocephalus by third ventriculostomy, and 3) several biopsy specimens can be obtained identifying tumors which will require further open surgery or adjuvant radiation and/or chemotherapy. However, complications and morbidities should be emphasized so as to be avoided with further technical experience.

• 농약과학회지
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• 제5권4호
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• pp.11-19
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• 2001

곤충의 난황형성에는 각종호르몬들이 먹이 등과 함께 매우 중요하게 작용하고 있으며, 이러한 호르몬들 중에서는 신경분비호르몬, 유약호르몬 및 엑디스테로이드 등이 주작용을 한다. 본 총설에서는 곤충호르몬을 포함한 곤충성장조절제가 곤충의 난황형성에 작용하여 어떤 영향을 주는지에 대하여 살펴보고 종합적 해충관리 인자로서 이용 가능성을 조사하였다. 곤충의 난황형성은 일반적으로 뇌에서 분비하는 신경분비호르몬의 작용과 난소에서 분비되는 엑디스테로이드 및 알라타체에서 분비되는 유약호르몬이 지방체를 자극하여 난황소전구물질을 합성하게 하며, 혈림프로 분비된 난황소 전구물질은 난모세포로 흡수되어 난발육이 이루어진다. 곤충호르몬을 포함한 곤충성장조절제는 이러한 난황형성과정 중에 각종 호르몬분비 기관(알라타체와 난소 등) 및 여러 가지 생리기관(지방체, 중장상피 그리고 침샘 등)에 작용하여 용해, 파괴 및 세포독성을 나타내 정상적인 생식작용을 하지 못하도록 한다. 따라서 곤충의 종류에 따라서는 포유동물에 독성이 낮은 곤충호르몬을 포함한 곤충성장조절제를 종합적 해충관리의 일환으로 사용함으로서 효과적인 해충방제가 가능할 것으로 보인다.

• 한국산학기술학회논문지
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• 제19권8호
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• pp.492-500
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• 2018

중소병원에서 근무하는 초보간호사의 병원감염관리에 대한 인지도와 수행 정도를 확인하고, 병원감염에 대한 기초자료를 제공하고자 실시된 서술적 조사연구이다. 2017년 9월15일부터 2017년 9월 30일까지 A시와 B시에 300병상 규모의 중소병원 2곳의 초보간호사 150명중 무응답 및 미흡한 응답자 11명을 제외한 139명을 대상으로 하였다. 본 연구에서 수집된 자료는 SPSS Win 22.0 프로그램을 이용하여 실수, 백분율, 평균, 표준편차, t-test, ANOVA, 사후검정은 $Scheff{\bar{e}}$ test로 분석하였다. 대상자의 일반적 특성에 따라 병원감염관리에 대한 인지도를 비교해 본 결과 요로 감염관리, 호흡기 감염 관리 그리고 소독 오염물품 관리 부분은 연령에서 유의한 차이가 있었고, 수행 정도는 손 씻기 영역에서는 근무부서와 직위, 수액요법영역은 감염관리 교육 필요성 여부(p<.001)에서, 요로감염관리 영역 및 호흡기 감염관리 영역(p=<.001)에서는 직위에 따라 차이가 있는 것으로 나타났다. 또한 병원감염관리에 대한 인지도와 수행 정도에 대한 차이를 살펴본 결과 손 씻기, 수액요법, 요로감염관리, 호흡기 감염관리, 감염성 폐기물 관리, 소독오염 물품관리영역의 모든 영역에서 인지도가 수행도 보다 모두 높게 나타났으며 모두 유의한 차이를 보였다. 경험과 지식이 부족한 초보간호사들이 병원감염관리 간호를 원활하게 수행하기 위해 이론적 지식을 바탕으로 수행도도 높일 수 있는 체계적인 병원감염관리 관련 교육프로그램이 구체적으로 개발 운영되어야 할 것이다.