• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권4호
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• pp.356-365
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• 2020

Purpose: There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus guidelines on management but it is unclear if these are sufficient or valid. Our study aims to assess the effect of clinical and laboratory variables, in addition to treatment modality on hospital length of stay (LOS) as a proxy variable for severity in pediatric patients admitted with AP. Methods: We conducted a retrospective chart review of patients between ages of 0-18 years, who were admitted with AP at 2 institutions between 2013-2018, John R. Oishei Children's Hospital (Buffalo, NY, USA) and Medical University of South Carolina Children's Hospital (Charleston, SC, USA). We constructed three linear regression models to analyze the effect of clinical signs of organ dysfunction, laboratory markers and fluid intake on hospital LOS. Results: Ninety-two patients were included in the study. The mean age was 12 years (range, 7.6-17.4 years), 55% were females, and median LOS was 3 days. The most frequent cause of AP was idiopathic. Our study showed that elevated blood urea nitrogen (BUN) on admission (p<0.005), tachycardia that lasted for ≥48 hours (p<0.001) and need for fluid resuscitation were associated with increase LOS. Total daily fluid intake above maintenance did not have a significant effect on the primary outcome (p=0.49). Conclusion: Elevated serum BUN on admission, persistent tachycardia and need for fluid resuscitation were associated with increase LOS in pediatric AP. Daily total fluid intake above recommended maintenance did not reduce LOS.

• 한국지열·수열에너지학회논문집
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• 제10권4호
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• pp.15-24
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• 2014

This study conducted a computational fluid dynamics(CFD) analysis to find an appropriate diameter or sectional area of air ducts and fluid pipes which have an electromagnetic pulse(EMP) shied to protect indoor electronic devices in special buildings like military fortifications. The result shows that the optimized outdoor air intake size can be defined with either the ratio of the maximum air velocity in the supply duct to the air intake size, or the shape ratio of indoor supply diffuser to the outdoor air intake. In the case of water channel, the fluid velocity at EMP shield with the identical size of the pipe, decreases by 25% in average due to the resistance of the shield. The enlargement of diameter at the shield, 2 step, improves the fluid flow. It illustrated that the diameter of downstream pipe size is 1step larger than the upstream for providing the design flow rate. The shield increases friction and resistance, in the case of oil pipe, so the average flow velocity at the middle of the shield increase by 50% in average. In consideration of the fluid viscosity, the oil pipe should be enlarged 4 or 5 step from the typical design configuration. Therefore, the fluid channel size for air, water, and oil, should be reconsidered by the engineering approach when EMP shield is placed in the middle of channel.

• 한국태양에너지학회 논문집
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• 제29권2호
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• pp.31-38
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• 2009

This study was conducted to forecast inner water temperature strata change by extracting deep water from a dam. For the methodology, the scope wherein the balance between the volume of low-temperature water intake through the virtual water intake opening as installed within the stored water area and the volume of water intake from the surrounding area is not destroyed was calculated through the CFD simulation technique using the computational fluid dynamics(CFD) interpretation method. This study suggested a supplementary method(diffuser) to avoid destroying the water temperature strata, and the effect was reviewed. In case of intake of the same volume, when the velocity of flow of water intake is reduced by increasing the pipe diameter, the destruction of water temperature strata can be minimized. When the area(height) where the intake of water is possible is low, a diffuser for interrupting the vertical direction inflow should be installed to secure favorable water intake conditions in case of water intake on the upper part. This study showed that there was no problem if the intake-enabled, low-temperature area was secured approximately 10m from the bottom when the scope that does not destroy the water temperature strata in case of water intake was forecast using the regression formula.

• Asian-Australasian Journal of Animal Sciences
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• 제24권8호
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• pp.1069-1085
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• 2011

In large-type goats that were fed on dry forage twice daily, dry forage intake was markedly suppressed after 40 min of feeding had elapsed. The objective of this study was to clarify whether or not increases in plasma osmolality and subsequent thirst sensations produced by dry forage feeding suppress dry forage intake. Eight large-type male esophageal- and ruminal-fistulated goats (crossbred Japanese Saanen/Nubian, aged 3 to 6 years, weighing $72.3{\pm}2.74$ kg) were used in two experiments conducted under sham feeding conditions. The animals were fed ad libitum a diet of roughly crushed alfalfa hay cubes for 2 h from 10:00 to 12:00 h during two experiments. Water was withheld during feeding in both experiments but was available for a period of 30 min after completion of the 2 h feeding period. In experiment 1, an intraruminal infusion of artificial parotid saliva (RIAPS) in the control replenished saliva lost via the esophageal fistula and an intraruminal infusion of hypertonic solution (RIHS) in the treatment was carried out in order to reproduce the effects of changing salt content due to feed entering the rumen. In experiment 2, the RIHS control was conducted in the same manner as the RIHS treatment of experiment 1. The treatment group consisted of RIHS-with an intravenous infusion of artificial mixed saliva (VIAMS) treatment that was carried out for 3 h to prevent increases in plasma osmolality during feeding. The results of the RIHS treatment in experiment 1 showed that ruminal fluid osmolality increased and then an increase in plasma osmolality was observed. This resulted in the production of thirst sensations and the reduction of cumulative dry forage intake to 43.3% (p<0.05) of the RIAPS control. The results of the RIHS-VIAMS treatment in experiment 2 indicated that ruminal fluid osmolality was the same as the RIHS control but plasma osmolality significantly decreased, and thirst level was markedly reduced. This caused a significant increase of 31.4% (p<0.05) in cumulative dry forage intake in the RIHS-VIAMS treatment compared to the RIHS control. These results indicate that increases in ruminal fluid osmolality during dry forage feeding indirectly suppresses dry forage intake by causing an increase in plasma osmolality and subsequently inducing thirst sensations. The results of the present study suggest that marked decreases in dry forage intake after 40 min of feeding are caused by increases in plasma osmolality and subsequent thirst sensations produced by dry forage feeding.

• 한국유체기계학회 논문집
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• 제12권4호
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• pp.14-22
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• 2009

The head-capacity curves for pumps developed by the pump manufacturer are based on tests of a single pump operating in a semi-infinite basin with no close walls or floors and with no stray currents. Therefore, flow into the pump intake is with no vortices or swirling. However, pump station designers relying on these curves to define the operating conditions for the pump selected sometimes meet the reductions of capacity and efficiency, as well as the increase of vibration and additional noise, which were caused by air-entered flow in the pump station. From this background, the authors are carrying out a systematic study on the flow characteristics of intakes within a sump of pump station model. Multi-intake sump model with anti-submerged vortex device basin is designed and the characteristics of submerged vortex is investigated in the flow field by numerical simulation. In this study, a commercial CFD code is used to predict the vortex generation in the pump station accurately. The analysed results by CFD show that the vortex structure and effect of anti-submerged vortex device are different at each pump intake channel.

• 생명과학회지
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• 제19권12호
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• pp.1743-1749
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• 2009

경력 50개월 이상 풀코스 완주 5회 이상인 중년남성 동호인 마라토너 8명을 대상으로 마라톤 시 물과 오이음료를 섭취하여 체액조절호르몬, C-반응단백에 미치는 영향을 구명하였다. 2회의 마라톤을 실시하여 첫 번째 마라톤경기는 물을 섭취, 두 번째 마라톤경기에서는 오이음료를 각각 총 10회, 총 710 ml을 섭취시켜 다음과 같은 결론을 얻었다. 체액조절 호르몬에서 ADH의 농도는 오이음료 섭취군이 물 섭취군 보다 경기 전, 종료 후, 종료 1시간 후 유의하게 감소하였으며, Renin의 활성도는 오이음료 섭취군과 물 섭취군이 경기 전에서 경기종료, 경기종료 1시간 후 유의하게 증가하였다. Aldosterone의 농도는 오이음료 섭취군과 물 섭취군이 경기 전, 종료에서 유의하게 증가하였다. C-반응단백은 장기간 운동과 염증반응에 관한 것으로 오이음료 섭취군과 물 섭취군에서 유의한 차이가 나타나지 않았다. 본 연구결과 마라톤 시 오이음료 섭취가 물 섭취보다 체액조절호르몬인 ADH에 긍정적인 효과를 미치는 것으로 나타났다. 이는 마라톤 시 발생하기 쉬운 탈진과 발열에 대한 수분 보충물의 하나로 오이음료가 물보다 긍정적인 영향을 미친 것으로 생각되며, 운동 후 체열의 상승과 오이섭취에 관한 연구들이 추후 필요하다고 사료된다.

• 한국유체기계학회 논문집
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• 제10권4호
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• pp.39-46
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• 2007

In large pump station, vortex generation such as free-surface vortex and submerged vortex occurring around pump intake, or at bell-mouth inlet has been an important flow characteristics which should be considered always to keep away the suction of air-entrained or cavitated flow. In this study, a commercial CFD code was used to predict accurately the vortex generation for the specified intake design. These result shows the preliminary result of submerged vortex prediction for the Turbo-machinery Society of Japan Sump Test CFD standard model. At bottom wall, air volume fraction (red color) was found in a large scale to explain the submerged vortex generation at particular operation and configuration condition. And these indicate the free surface formation behind the bell mouth. Particularly, non-uniform approaching flow is a major parameter to govern the occurrence of the free-surface vortex. Futhermore the comparison between turbulence ($k-{\epsilon}$ & $k-{\omega}$ model) mode were executed in this study.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2005년도 연구개발 발표회 논문집
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• pp.575-581
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• 2005

• 한국자동차공학회논문집
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• 제5권3호
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• pp.47-53
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• 1997

The importance of intake system can not be overstressed in the recent heavy duty commercial vehicle design. The basic requirements of intake system are to have less flow resistance and better air cleaning performance which have direct effects on the performance and service life of engine. In order to improve the performance of engine intake system, the flow phenomena in the intake system should be fully understood. With readily availble CFD code, the numerical analysis becomes the more reliable tools for flow optimization in recent design work. In this research, flow field in the intake system was analyzed by STAR-CD, the 3-D computational fluid dynamics code. Especially, the flow inside of air cleaner was thoroughly analyzed. Pressure distribution and velocity profile in the air cleaner and intake duct was obtained. Having the dust seperated from incoming air at the expense of less pressure drop is the ultimate goal for the research.

• 한국유체기계학회 논문집
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• 제3권4호
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• pp.52-58
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• 2000

The numerical study on the waterhammer was carried out for the intake pumping station of the metropolitan water supply 6th stage project. Because the waterhammer problems as a result of the pump power failure were the most important, these situations were carefully investigated. The surge tank and the stand pipes effectively protected the tunnels md the downstream region of pipeline from the pressure surge. In case the moment of inertia of the pump and motor was above $5080\;kg{\cdot}m^2$, the column separation did not occur in the pipeline between the pumping station and the inlet of 1st tunnel. As the moment of inertia increased, the pressure surges decreased in the pipeline conveying raw water. The pump control valve was chosen as the main surge suppression device for the intake pumping station. After power failure, the valve disc should be rapidly closed in 2.5 seconds and controlled the final closure to 15 seconds by the oil dashpot. If the slamming happened to the pump control valve, there was some danger of this system damaging. As the reverse flow through the valve increased, the upsurge extremely increased.