• Title/Summary/Keyword: Flow imaging

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Radiopharmaceuticals Used in Cardiac Imaging (심장영상에 이용되는 방사성의약품)

  • Hwang, Kyung-Hoon;Chung, Yong-An;Lee, Byeong-Il;Lee, Yu-Kyung;Lee, Min-Kyung;Choe, Won-Sick
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.3
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    • pp.174-178
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    • 2009
  • Many radiopharmaceuticals have been developed and wildy used in the imaging cardiac function. Myocardial perfusion imaging (MPI) is a well established noninvasive method of assessing coronary blood flow and has been widely used in patients diagnosed or suspected with coronary artery diseases. The innovation of radiopharmaceuticals used in the cardiac imaging is one of the most important contributors to the development of nuclear cardiology. Thallium-201 and various technetium-99m agents have been globally used for myocardial perfusion SPEG, and N-13 ammonia (13NH3), rubidium-82 (82Rb), 0-15 water (H2150) for myocardial perfusion PET. As well as the cardiac perfusion studies, new radiopharmaceuticals that visualize fat metabolism or receptors of the sympathetic nervous system have successfully been applied to clinical practice. Useful information can be obtained for diagnosing coronary artery disease, evaluating patients' condition, or assessing therapeutic effects. In this review, we describe the characteristics and clinical usefulness of radiopharmaceuticals used for cardiac SPEG and PET.

Development of a Real-time Medical Imaging System Combined with Laser Speckle Contrast Imaging and Fluorescence Imaging (형광과 레이저 스펙클 대조도 이미징을 결합한 실시간 의료영상 시스템 개발)

  • Shim, Min Jae;Kim, Yikeun;Ko, Taek Yong;Choi, Jin Hyuk;Ahn, Yeh-Chan
    • Journal of Biomedical Engineering Research
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    • v.42 no.3
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    • pp.116-124
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    • 2021
  • It is important to differentiate between the target tissue (or organ) and the rest of the tissue before incision during surgery. And when it is necessary to preserve the differentiated tissues, the blood vessels connected to the tissue must be preserved together. Various non-invasive medical imaging methods have been developed for this purpose. We aimed to develop a medical imaging system that can simultaneously apply fluorescence imaging using indocyanine green (ICG) and laser speckle contrast imaging (LSCI) using laser speckle patterns. We designed to collect images directed to the two cameras on a co-axial optical path and to compensate equal optical path length for two optical designs. The light source used for fluorescence and LSCI the same 785 nm wavelength. This system outputs real-time images and is designed to intuitively distinguish target tissues or blood vessels. This system outputs LSCI images up to 37 fps through parallel processing. Fluorescence for ICG and blood flow in animal models were observed throughout the experiment.

Usefulness of Reverse Flow Prevention Valves for Back-flow Prevention of Gadolinium Based Contrast Agent in Dynamic Examination of Magnetic Resonance Imaging (자기공명영상 동적검사 시 조영제 역류방지용 밸브의 유용성)

  • Son, Soon-Yong
    • The Journal of the Korea Contents Association
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    • v.20 no.6
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    • pp.439-444
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    • 2020
  • The purpose of this study is to seek an alternative method to prevent the contamination of normal saline caused by the back-flow of Gadolinium Based Contrast Agent(GBCA) by the use of auto-injector for dynamic MRI. The research method is to manufacture the non-return valve as an alternative to the existing, and to examine the usefulness of the normal saline by dividing the state of normal saline into three groups. The signal intensity were compared. As a result, there was no statistically significant difference between normal saline before injection of group 1 and group 3 non-return valve (p> 0.05). It is analyzed that the self-produced non-return valve completely blocked the GBCA back to normal saline when the GBCA was injected. In conclusion, the application of the non-return valve presented in this study for dynamic MRI imaging using the auto injector can prevent normal saline contamination due to GBCA back-flow.

EXPERIMENTAL APPROACHES FOR WATER DISCHARGE CHARACTERISTICS IN PEMFC USING NEUTRON IMAGING TECHNIQUE AT CONRAD, HMI

  • Kim, Tae-Joo;Kim, Jong-Rok;Sim, Cheul-Muu;Lee, Sung-Ho;Son, Young-Jin;Kim, Moo-Hwan
    • Nuclear Engineering and Technology
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    • v.41 no.1
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    • pp.135-142
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    • 2009
  • In this investigation, we prepared a 1 and 3-parallel serpentine single PEMFC, which has an active area of $100\;cm^2$ and a flow channel cross section of $1{\times}1mm$. Distribution and transport of water in a non-operating PEMFC were observed by varying flow types and the flow rates (250, 400, and 850 cc/min). This investigation was performed at the neutron imaging facility at the CO1d Neutron RAdiography facility (CONRAD), HMI, Germany of which the collimation ratio and neutron fluence rate are 250, $1{\times}10^{6}n/s/cm^2$, respectively. The neutron image was continuously recorded by a scintillator and lens-CCD coupled detector system every 10 seconds. It has been observed that although the distilled water was supplied into the cathode channel only, the neutron image showed a water movement from the cathode to the anode channel. The water at the cathode channel was completely discharged as soon as the pressurized air was supplied. But the water at the anode channel was not easily removed by the pressurized air except for the 3-parallel serpentine type with 850cc/min of air flow rate. Moreover, the water at the MEA wasn't removed for any of the cases.

Multi-phase Flow Velocity Measurement Technique using Shadow Graphic Images (다위상 유체 속도 계측을 위한 영상기법 적용)

  • Ryu, Yong-Uk;Jung, Kwang-Hyo
    • Journal of Ocean Engineering and Technology
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    • v.26 no.3
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    • pp.61-65
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    • 2012
  • Air-water flow measurements are of importance for the coastal and ocean engineering fields. Although kinematic investigations of the multi-phase flows have been conducted for long time, velocity measurements still are concerned with many researchers and engineers in coastal and ocean areas. In the present study, an imaging technique using shadowgraphy and fiber optic probe for velocity measurements of air bubbles is introduced. The shadow graphy image technique is modified from the typical image velocimetry methods, and optical fibers are used for the well-known intrusive coupled phase-detection probe system. Since the imaging technique is a non-intrusive optical method from the air, it is usually applied for 2D flows. On the other hand, the double fiber optic probes touch flows regardless of flow patterns. The results of the flow measurements by both methods are compared and discussed. The methods are also applied to the measurements of overtopping flows by a breaking wave over the structure fixed on the free surface.