• Progress in Medical Physics
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• v.28 no.1
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• pp.1-10
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• 2017

The difference between three-dimensional (3D) and four-dimensional (4D) dose could be affected by factors such as tumor size and motion. To quantitatively analyze the effects of these factors, a phantom that can independently control each factor is required. The purpose of this study is to develop a deformable lung phantom with the above attributes and evaluate the characteristics. A phantom was designed to simulate diaphragm motion with amplitude in the range 1~7 cm and period up to ${\geq}2s$ of regular breathing. To simulate different tumors sizes, custom molds were created using a 3D printer and filled with liquid silicone. The accuracy of the phantom diaphragm motion was assessed by comparing measured motion with predicted motion. Because the phantom diaphragm motion is not identical to the tumor motion, the correlation between the diaphragm and tumor motions was calculated by a curve fitting method to emulate user-intended tumor motion. Tumors of different sizes were located at same position, and tumor set-up positions were evaluated. The accuracy of phantom diaphragm motion was better than 1 mm. The diaphragm-tumor correlation showed that the tumor motion in the superior-inferior direction increased with increasing diaphragm motion. The tumor motion was larger in the $10cm^3$ tumor than in the $90cm^3$ tumor. The range of difference between the tumor set-up positions was 0 to 0.45 cm. This phantom showed independently adjusting factors such as tumor size and motion to facilitate quantitative analysis of the dosimetric impact of respiratory motion according to these factors.

• The KIPS Transactions:PartB
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• v.14B no.4
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• pp.287-294
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• 2007

Many classification algorithms for real world data suffer from a data class imbalance problem. To solve this problem, various methods have been proposed such as altering the training balance and designing better sampling strategies. The previous methods are not satisfy in the distribution of the input data and the constraint. In this paper, we propose a focused sampling method which is more superior than previous methods. To solve the problem, we must select some useful data set from all training sets. To get useful data set, the proposed method devide the region according to scores which are computed based on the distribution of SOM over the input data. The scores are sorted in ascending order. They represent the distribution or the input data, which may in turn represent the characteristics or the whole data. A new training dataset is obtained by eliminating unuseful data which are located in the region between an upper bound and a lower bound. The proposed method gives a better or at least similar performance compare to classification accuracy of previous approaches. Besides, it also gives several benefits : ratio reduction of class imbalance; size reduction of training sets; prevention of over-fitting. The proposed method has been tested with kNN classifier. An experimental result in ecoli data set shows that this method achieves the precision up to 2.27 times than the other methods.

• Journal of Korean Ophthalmic Optics Society
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• v.6 no.1
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• pp.13-29
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• 2001

A mathematical model was proposed to analyze the vibration of diaphragm, such as the contact lenses fitted on the eyes, being subjected to the external sinusoidal pressure. The model incorporates the differential equations and their numerical solution program, based on the wave equations. Turbo-C and graphic software, formulated to describe the dependence of the various parameters involved in the vibration. The model predicts the radial distribution of amplitude, frequency dependence of both average displacement amplitude and the power of diaphragm whose edge is being either simply supported or rigidly clamped in vibration. The effect of variables such as thickness, radius, damping coefficients on the vibration characteristics was illustrated by the computer simulation of the derived program. As the frequency of driving pressure increases above the certain value determined by the boundary conditions and parameters the wave shape or pattern changes from simple arc to belly or loops having double antinode. It seems that the effect of outer antinode progressively increases as the frequency increases. If this kind of phenomena occurs to the contact lens on the cornea in vivo, it may cause an abnormal correction power in the lenses or pull off the eye due the increased rise of outer part of the lens.

• Korean Journal of Microbiology
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• v.42 no.4
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• pp.326-331
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• 2006

In the present study, we examined biosorption characteristics of heavy metals onto the extracellular polysaccharide (EPS) produced by the purple nonsulfur photosynthetic bacteria Rhodopseudomonas sp. KH4, which was isolated from a stream in Anyang, Kyonggi-Do. When Cd (100 mg/L) and Cu (100 mg/L) were added to EPS (1.0 g/L) in the optimal condition (Cd; pH 8, Cu; pH 5, $40^{\circ}C$), 84.2 mg/L of Cd and 70.0 mg/L of Cu were adsorbed within 30 min and 10 min, respectively. When 100 mg/L of Cd and Cu were present as mixture, 16.8 mg/L of Cd and 48.7 mg/L of Cu were adsorbed at $25^{\circ}C$, pH 5. The maximum adsorption capacity determined by fitting Langmuir isotherms model was suitable for describing the biosorption of Cd (76.9 mg/g) and Cu (67.1 mg/g) by EPS. The neutral monosaccharide in the EPS determined by GC consisted of arabinose (2.4%), glucose (7.1%) and mannose (90.5%).

• Horticultural Science & Technology
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• v.34 no.6
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• pp.912-923
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• 2016

Watermelon production is often limited by powdery mildew in areas with a large daily temperature range. Development of resistant watermelon cultivars can protect against powdery mildew; however, little is known about the characteristics of its causal agents. Here, we identified the genus and race of a causal pathogen of powdery mildew in Ansung province of South Korea, and developed molecular markers for the generation of resistant watermelon cultivars. The causal pathogen was determined to be Podosphaera xanthii based on multiple sequence alignments of internal transcribed spacers (ITS) of rDNA. The physiological race was identified as 1W, and the Ansung isolate was named P. xanthii 1W-AN. Following inoculation with the identified P. xanthii 1W-AN, we found inheritance of the resistant gene fitting a single dominant Mendelian model in a segregated population ('SBA' ${\times}$ PI 254744). To develop molecular markers linked to fungus-resistant loci, random amplified polymorphic DNA (RAPD) was accomplished between DNA pooled from eight near-isogenic lines (NILs; $BC_4F_6$), originated from PI 254744 and susceptible 'SBB' watermelon. After sequencing bands from RAPD were identified in all eight NILs and PI254744, 42 sequence-characterized amplifiedregion (SCAR) markers were developed. Overall, 107 $F_2$ plants derived from $BC_4F_6$ NIL-1 ${\times}$ 'SBB' were tested, and one SCAR marker was selected. Sequence comparison between the SCAR marker and the reference watermelon genome identified three Nco I restriction enzyme sites harboring a single nucleotide polymorphism, and codominant cleavage-amplified polymorphic site markers were subsequently developed. A CAPS marker was converted to a high-resolution melt (HRM) marker, which can discriminate C/T SNP (254PMR-HRM3). The 254PMR-HRM3 marker was evaluated in 138 $F_{2:3}$ plants of a segregating population ('SBA' ${\times}$ PI254744) and was presumed to be 4.3 cM from the resistance locus. These results could ensure P. xanthii 1W-AN resistance in watermelon germplasm and aid watermelon cultivar development in marker-assist breeding programs.

• The Journal of Korean Academy of Prosthodontics
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• v.44 no.3
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• pp.284-294
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• 2006

Statement of problem. Proliferation of Candida albicans is primarily within the plaque on the fitting surface of the denture rather than on the inflamed mucosa. Consequently, the treatment of the denture is equally important as treatment of the tissue. Cleansing and disinfection should be efficiently carried-out as the organisms can penetrate into the voids of the acrylic resin and grow in them, from which they can continue to infect and reinfect bearing tissues. Purpose. The purpose of this study was to evaluate the applicability of photocatalytic reaction to eliminate Candida albicans from acrylic resin denture base, and to investigate the anti-fungal effect with various UVA illumination time. Materials and Methods. The specimens were cured by the conventional method following the manufacturer's instruction using thermal polymerized denture base resin (Vertex RS: Dentimex, Netherlands). $TiO_2$ photocatalyst sol(LT), which is able to be coated at normal temperature, was made from the Ti-alkoxide progenitor. The XRD patterns, TEM images and nitrogen absorption ability of the $TiO_2$ photocatalyst sol(LT) were compared with the commercial $TiO_2$ photocatalyst P-25. The experimental specimens were coated with the mixture of the $TiO_2$ photocatalyst sol(LT) and binder material (silane) using dip-coater, and uncoated resin plates were used as the control group. Crystallinity of $TiO_2$ of the specimen was tested by the XRD. Size, shape and chemical compositions were also analyzed using the FE-SEM/ EDS. The angle and methylene blue degradation efsciency were measured for evaluating the photocatalytic activity of the $TiO_2$ film. Finally, the antifungal activity of the specimen was tested. Candida albicans KCTC 7629(1 ml, initial concentration $10^5$ cells/ ml) were applied to the experiment and control group specimens and subsequently two UVA light source with 10W, 353 nm peak emission were illuminated to the specimens from 15cm above. The extracted $2{\mu}l$ of sample was plated on nutrient agar plate ($Bacto^{TM}$ Brain Heart Infusion; BD, USA) with 10 minute intervals for 120 minute, respectively. It was incubated for 24 hours at $37^{\circ}C$ and the colony forming units (CFUs) were then counted. Results. Compared the characteristics of LT photocatalyst with commercial P-25 photocatalyst, LT were shown higher activity than P-25. The LT coated experimental specimen surface had anatase crystal form, less than 20 nm of particle size and wide specific surface area. To evaluate the photocatalytic activity of specimens, methylene blue degradation reaction were used and about 5% of degradation rate were measured after 2 hours. The average contact angle was less than $20^{\circ}$ indicating that the LT photocatalyst had hydrophilicity. In the antifungal activity test for Candida albicans, 0% survival rate were measured within 30 minute after irradiation of UVA light. Conclusion. From the results reported above, it is concluded that the UVA-LT photocatalytic reaction have an antifungal effect on the denture surface Candida albicans, and so that could be applicable to the clinical use as a cleaning method.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.10A
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• pp.1579-1587
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• 1999

Bias-dependent noise models of $0.2\mu\textrm{m}$ gate length P-HEMT's which are scalable with gate width are proposed. To predict S-parameters of the P-HEMT's the intrinsic parameters except for $\tau$ subtracted the offsets introduced in this paper are normalized to the gate width and then scaled. The small-signal model parameters are expressed as fitting functions of the drain current to $\textrm{I}_{dss}$ ratio and gate width. In addition, to estimate accurately noise parameters the noise temperature $\textrm{T}_{g}$ of the intrinsic resistance, the equivalent noise conductance $\textrm{G}_{ni}$ of the gate current noise source, and the equivalent noise conductance $\textrm{G}_{no}$ of the drain current noise source are adopted as the noise model parameters. The extracted values of $\textrm{T}_{g}$ are nearly independent of drain current and gate width and their average is around the ambient temperature. The extracted values of $\textrm{G}_{ni}$ are small enough to be neglected to the circuit characteristics. From the comparison of the noise model with only $\textrm{G}_{no}$ and that having $\textrm{T}_{g}$, $\textrm{G}_{ni}$ and $\textrm{G}_{no}$ to the measured data it is fund that even the former model is in good agreement with the measured noise parameters. Thus, from a practical point of view the noise model having only the drain current noise source is confirmed as a scalable bias-dependent model.

• Clean Technology
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• v.19 no.4
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• pp.430-436
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• 2013

In this study, experiments on the static adsorption of benzene were carried out using activated carbon made from Pinus koraiensis which is normally discarded waste timber in South Korea. The experiment were performed at 303.15 K, 318.15 K and 333.15 K under the pressure up to 7.999 kPa. Isothermal adsorption curves were obtained using Langmuir isotherm, Freundlich isotherm and Toth isotherm for comparison. Based on the fitting, the adsorption quantity of Benzene (q), the isothermal adsorption curves obtained from Langmuir isotherm and Toth isotherm showed the higher accuracy. Although there was little difference in accuracy between result from Langmuir isotherm and that from Toth isotherm, the adsorption quantity of Benzene (q) was expressed in terms of Langmuir isotherm because less parameters were required for Langmuir isotherm than for Toth isotherm. Moreover SEM images of the activated carbon from Pinus koraiensis and the commercial activated carbon were taken to observe the pore size development. The results showed that the perforation development of activated carbon from Pinus koraiensis (waste timber) was better than that of commercial activated carbon (DARCO A.C., SPG-100 A.C.). Adsorption quantity of benzene on activated carbon from Pinus koraiensis was confirmed to be higher than that on commercial activated carbon. Therefore, we may conclude that it is feasible to commercialize the process to manufacturing activated carbon from waste timber.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.1
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• pp.98-105
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• 2013

This paper presents a finite-difference time-domain(FDTD) simulation and a data processing technique for radar sensing of the internal structure of a wall using an ultra-wide band antenna. We first designed an ultra-wide band anti-podal vivaldi antenna with a frequency range of 0.3~7 GHz which is chosen to be relatively low after considering the characteristics of wave attenuation, wall penetration, and range resolution. In this study the two-dimensional FDTD technique was used to simulate a wall-penetration-radar experiment under practical conditions. The next, the measured radiation pattern of the practical antenna is considered as an equivalent source in the FDTD simulation, and the reflection data of a concrete wall and targets are obtained by using the simulation. Then, a data processing technique has been applied to the FDTD reflection data to get a radar image for remote sensing of the internal structure of the wall. We compared the two different source excitations in the FDTD simulation; (1) commonly-used isotropic point sources and (2) polynomial curve fitting sources of the measured radiation pattern. As a result, when we apply the measured antenna pattern into the FDTD simulation, we could obtain about 2.5 dB higher signal to noise level than using a plane wave incidence with isotropic sources.

• The Journal of the Acoustical Society of Korea
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• v.37 no.2
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• pp.99-109
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• 2018

The precision of the vibration-sensors, contact or non-contact types, is usually satisfactory for the practical measurement applications, but a sensor is confined to the measurement of a point or a direction. Although the precision and frequency span of the low-cost camera are inferior to these sensors, it has the merits in the cost and in the capability of simultaneous measurement of a large vibrating area. Furthermore, a camera can measure multi-degrees-of-freedom of a vibrating object simultaneously. In this study, the calibration method and the dynamic characteristics of the low-cost machine vision camera as a sensor are studied with a demonstrating example of the two-dimensional vibration of a cantilever beam. The planar image of the camera shot reveals two rectilinear and one rotational motion. The rectilinear vibration motion of a single point is first measured using a camera and the camera is experimentally calibrated by calculating error referencing the LDV (Laser Doppler Vibrometer) measurement. Then, by measuring the motion of multiple points at once, the rotational vibration motion and the whole vibration motion of the cantilever beam are measured. The whole vibration motion of the cantilever beam is analyzed both in time and frequency domain.