• 한방안이비인후피부과학회지
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• 제33권4호
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• pp.133-144
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• 2020

Objectives : The purpose of this study is to report the effect of Korean medicine treatment on limitation of eye movement in Miller-Fisher Syndrome. Methods : A patient was treated with herbal medicines, acupuncture(including electropuncture, phamacopuncture), Moxibustion and cupping therapy. To evaluate the result of this treatment, we used photographs of eye movement, Scott and Kraft score of both eye, length of eyeball movement and visual analogue scale(VAS) for subjective symptoms. Results : After treatment, the limitation of eye movement and diplopia were remarkably improved. Also, other symptoms such as dizziness, gait disturbance, facial nerve disorder were disappeared. Conclusions : This study suggests that Korean medicine treatments are effective for patient with limitation of eye movement in Miller-Fisher Syndrome.

• 재활간호학회지
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• 제2권2호
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• pp.163-175
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• 1999

This study was done to identify the effectiveness of a proper positioning on musculoskeletal complication on patient with Stroke by using a quasi-experimental study. A total of 18 patients were selected as a subject from June 1st to October 31th 1998 who had been hospitalized at Intensive Care Units in K medical center. A experimental group consists of 8 patients who were given proper positioning every two hours. A control group consists of 10 patients who were given traditional positioning. The collected data were analyzed by SPSS windows including $X^2$-test (Fisher's exact method), Wilcoxon Rank Sum test and McNemar test. The result of this study was summerized as follows : 1) The experimental group with proper positioning has shown lower shoulder pain score, dorsiflexion contracture score, Shoulder subluxation score and higher Range of Motion and than the control group. 2) The experimental group with proper positioning has shown lower muscle pain score and edema score than the control group, but it was not statistically significant.Therefore, proper positioning could be applied as an independent nursing intervent ion for patients on Stroke in order to facilitate rehabilitation.

• Communications for Statistical Applications and Methods
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• 제8권2호
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• pp.357-366
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• 2001

The present paper develops a method to check the propriety of link functions for binary data. In order to parameterize a certain type of goodness of the link, a family of link functions indexed by a shape parameter is proposed. I first investigate the maximum likelihood estimation of the shape parameter as well as regression parameters and then derive their large sample behaviors of the estimators. A score test is considered to evaluate the goodness of the current link function. For illustration, I employ two families of power transformations, the modulus transformation by John and Draper (1980) and the extended power transformation by Yeo and Johnson (2000), which are appropriate to detect symmetric and asymmetric inadequacy of the selected link function. respectively.

• Annals of Clinical Neurophysiology
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• 제13권1호
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• pp.44-47
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• 2011

Background: Miller-Fisher syndrome (MFS) is characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia, and is considered a variant form of Guillain-Barre syndrome. Although some cases of delayed-onset facial palsy in MFS have been reported, the characteristics of this facial palsy are poorly described in the literature. Methods: Between 2007 and 2010, six patients with MFS were seen at our hospital. Delayed facial palsy, defined as a facial palsy that developed while the other symptoms of MFS began to improve following intravenous immunoglobulin treatment, was confirmed in four patients. The clinical and electrophysiological characteristics of delayed facial palsy in MFS, as observed in these patients, are described here. Results: Four patients with delayed-onset facial palsy were included. Delayed facial palsy developed 8-16 days after initial symptom onset (5-9 days after treatment). Unilateral facial palsy occurred in three patients and asymmetric facial diplegia in one patient. The House-Brackmann score of facial palsy was grade III in one patient, IV in two patients, and V in one patient. None of the patients complained of posterior auricular pain. Facial nerve conduction studies revealed normal amplitude in all four patients. The blink reflex showed abnormal prolongation in two patients and the absence of action potential formation in two patients. Facial palsy resolved completely in all four patients within 3 months. Conclusions: Delayed facial palsy is a frequent symptom in MFS and resolves completely without additional treatment. Thus, standard treatment and patient reassurance are sufficient in most cases.

• Journal of Dental Anesthesia and Pain Medicine
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• 제20권5호
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• pp.303-312
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• 2020

Background: Lidocaine is the gold standard local anesthetic (LA) for UK pediatric dental treatment. Recent reports suggest frequent Articaine use in Europe and Canada, with evidence indicating more profound anesthesia. The aim of this study was to examine pediatric dentistry specialist experiences and practices relating to Articaine administration in the UK. Methods: A literature review was followed by a survey using an anonymous 15-item electronic questionnaire, which was sent to 200 registered British Society of Pediatric Dentistry (BSPD) specialists. Descriptive analyses, Z score, chi-squared test, Fisher's exact test, and Spearman's correlation test were performed. Results: Sixty-one (30.5%) participants responded, and 12 (19.7%) indicated Articaine as their first line anesthetic. Articaine was used daily or weekly by 38 (62.3%) respondents, depending on the clinical context. Articaine was commonly used to avoid inferior alveolar nerve blocks and gain more profound anesthesia in abscessed or hypomineralized teeth. Participants reported significantly more adverse effects with lidocaine (Fisher's exact test, P < 0.0001) than with Articaine. Articaine was most often administered in children aged > 4 years via infiltration techniques. Only 15 (24.6%) respondents reported awareness of guidelines for Articaine use in pediatric patients. Conclusions: Articaine use in pediatric dentistry is common; however, evidence supporting its practice is limited. Several specialists follow conventions based on anecdotal evidence. Formulating guidance to aid decision-making when treating pediatric patients under LA would be beneficial.

• 지역사회간호학회지
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• 제20권2호
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• pp.161-168
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• 2009

Purpose: This research was conducted to investigate perceived health status, health promoting behaviors and depression level in Korean and foreign students at women's university. Methods: The sample group of this study consists of 100 Korean students at a women's university and 98 foreign students from China and Vietnam who were enrolled at the same university in G City. The research results were analyzed using the SAS program (Version 8.2) with Chi-square test, Fisher's exact test and t-test. Results: 1) The Korean students showed a significantly higher score in drinking and smoking than foreign students. Also, age, religion, part time job, stress and allowance were significantly different between the two groups. 2) The foreign students showed a significantly higher score in perceived health status and health promoting behavior than the Korean students. 3) The foreign students showed a significantly higher score in depression than the Korean students. Conclusion: In the development of health programs for foreign students, it is necessary to focus on reducing depression and to consider the traditions of their own countries. It is desired to conduct further study about health promoting behavior and factors affecting health with respect to the countries where the foreign students originated.

• Journal of Korean Neurosurgical Society
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• 제67권2호
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• pp.177-185
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• 2024

Objective : Delayed cerebral ischemia (DCI) is a major cause of disability in patients who survive aneurysmal subarachnoid hemorrhage (aSAH). Systemic inflammatory markers, such as peripheral leukocyte count and systemic immune-inflammatory index (SII) score, have been considered predictors of DCI in previous studies. This study aims to investigate which systemic biomarkers are significant predictors of DCI. Methods : We conducted a retrospective, observational, single-center study of 170 patients with SAH admitted between May 2018 and March 2022. We analyzed the patients' clinical and laboratory parameters within 1 hour and 3-4 and 5-7 days after admission. The DCI and non-DCI groups were compared. Variables showing statistical significance in the univariate logistic analysis (p<0.05) were entered into a multivariate regression model. Results : Hunt-Hess grade "4-5" at admission, modified Fisher scale grade "3-4" at admission, hydrocephalus, intraventricular hemorrhage, and infection showed statistical significance (p<0.05) on a univariate logistic regression. Lymphocyte and monocyte count at admission, SII scores and C-reactive protein levels on days 3-4, and leukocyte and neutrophil counts on days 5-7 exhibited statistical significance on the univariate logistic regression. Multivariate logistic regression analysis revealed that monocyte count at admission (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.04-2.65; p=0.036) and SII score at days 3-4 (OR, 1.55; 95% CI, 1.02-2.47; p=0.049) were independent predictors of DCI. Conclusion : Monocyte count at admission and SII score 3-4 days after rupture are independent predictors of clinical deterioration caused by DCI after aSAH. Peripheral monocytosis may be the primer for the innate immune reaction, and the SII score at days 3-4 can promptly represent the propagated systemic immune reaction toward DCI.

• 생물정신의학
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• 제25권4호
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• pp.110-117
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• 2018

Objectives This study aimed to investigate the relationship between depressive and anxiety symptoms and tardive dyskinesia (TD) and reveal the association of cognitive function and TD in patients with schizophrenia. Methods We recruited 30 schizophrenia patients with TD and 31 without TD from a national mental hospital in South Korea. To assess depressive and anxiety symptoms, the Beck Depression Inventory-II (BDI-II) and the Beck Anxiety Inventory (BAI) were conducted. Using the five-factor structure of the BDI-II and BAI, somatic anxiety, cognitive depression, somatic depression, subjective anxiety, and autonomic anxiety were assessed. Computerized neurocognitive function test (CNT) was performed to assess levels of cognitive functions. We compared the clinical characteristics, levels of cognitive functions, and depressive and anxiety symptoms between schizophrenia patients with TD and without TD. Chi-square test, Fisher's exact test, independent t-test and Mann Whitney U test were conducted to compare two groups. Pearson correlation analysis was conducted to evaluate relationships among the abnormal involuntary movement scale (AIMS), BDI-II, BAI, somatic anxiety, cognitive depression, somatic depression, subjective anxiety, and autonomic anxiety. Results The subjects with TD had significantly lower score on the cognitive depression than those without TD (t = -2.087, p = 0.041). There were significant correlations between the AIMS score and the BDI-II score (r = -0.386, p = 0.035) and between the AIMS score and cognitive depression score (r = - 0.385, p = 0.035). Conclusions Our findings suggest the inverse relationship between severities in TD and depression and support the assumption that there is an inverse relationship between the pathophysiology of TD and depression.

• 한국산학기술학회논문지
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• 제14권7호
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• pp.3349-3357
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• 2013

본 연구의 목적은 PBL 연계 시뮬레이션 기반 통합간호교육과정을 이수한 신졸업간호사와 교과목 중심의 전통적 간호교육과정을 이수한 신졸업간호사간의 간호수행능력정도와 간호수행능력 자신감의 차이를 표준화환자 기반 간호수행평가를 활용하여 비교분석하는 것이다. 연구대상자는 전통적 간호교육과정을 이수한 신졸업간호사 39명과 통합간호교육과정을 이수한 신졸업간호사 35명, 총 74명이었다. 연구방법은 두 대상자 그룹간에 표준화환자 기반 간호실무능력 평가 시험에서 간호수행능력 평가점수와 간호수행능력 자신감을 비교하기 위한 비동등성 대조군 사후 시차설계를 적용한 유사 실험 연구로 수집된 자료는 SPSS 19.0 프로그램을 사용하여, Fisher's exact test, t-test, Pearson's correlation coefficient, ANCOVA를 이용하여 분석하였다. 표준화환자를 활용한 간호실무수행능력 평가시험을 실시한 결과 통합간호교육과정 이수 신졸업간호사와 교과목 중심의 전통적 간호교육과정 이수 신졸업간호사 간에 표준화 환자가 채점한 간호수행능력 점수는 차이가 없었으나, 통합간호교육과정 이수 신졸업간호사의 교수자가 평가한 기술적 술기 점수, 비기술적 술기 점수와 간호수행능력에 대한 자신감이 대조군에 비해 유의하게 높았다. 본 연구의 결과를 바탕으로 간호교육과정에 PBL 연계 시뮬레이션 기반 교과를 적용할 것을 제언하며, 통합간호교육과정을 이수한 신졸업간호사의 임상간호 현장에서의 실무능력과 환자 성과 변화를 장기추적 관찰하는 추후 연구가 필요하다.

• 전자공학회논문지
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• 제52권8호
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• pp.117-125
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• 2015

본 논문은 '좌', '우' 방향 제어를 위해 취득된 EEG(Electroencephalogram) 신호 기반 분류 알고리즘과 EEG 센서, Labview, DAQ, Matlab, 주행로봇으로 구성된 방향 제어 시스템을 제안한다. 제안된 알고리즘은 DWT(Discrete Wavelet Transform)로 추출된 주파수대역 정보를 특징으로 이용하며, Fishers score를 이용하여 변별력이 높은 주파수 대역의 특징을 선별한다. 또한, SVM (Support Vector Machine)을 이용하여 분류 성능이 최고가 되는 특징벡터의 조합을 제안하고, 잘못된 판정에 의한 오동작을 방지하기 위한 MLD(Maximum Likelihood Decision) 기반의 판정보류 알고리즘도 제안한다. 제안된 알고리즘에 의해 선택된 4개의 특징벡터는 국제 표준 전극 배치법에 따른 P8 채널의 d2(16-32Hz), d5(2-4Hz) 주파수 대역의 전압의 절대 값 평균과 표준편차이다. SVM 분류기로 실험한 결과 98.75%의 정확도와 1.25%의 오류율 성능을 보였다. 또한, 오류 확률 70%를 판정 보류로 규정할 경우, 제안된 알고리즘은 인식률 95.63%의 정확도와 오류율 0%을 보였다.