• 한국전자통신학회논문지
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• 제2권2호
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• pp.92-98
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• 2007

수산용 의약품의 목록을 데이터베이스 화 한 어류약물정보시스템엔 상품명, 대상어종, 유효성분, 제조회사명, 적응증(질병) 등 약물에 대한 다양한 자료와 제조회사정보, 식품의 기준 및 규격에 관한 자료가 들어있다. 또한 추후에는 어류 질병에 대한 상세 자료를 데이터베이스 화 한 어류질병정보시스템을 구축할 것이다. 따라서 약물정보시스템과 질병정보시스템을 근간으로 한 어류질병판별시스템에서 질병 판정 후 치료에 필요한 처방전 발행과 약품 주문 등에 응용 활용할 것을 제안한다.

• 한국어병학회지
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• 제23권3호
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• pp.379-388
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• 2010

This paper presents a computer program for easy and rapid disease diagnosis of olive flounder diseases. To design the program, standard diagnosis process of the 14 olive flounder diseases was first setup, then implemented four-steps diagnosis program. To run program, first input fundamental information such as water temperature, size of the diseased fish. Then sequentially, three categories of key factors for disease diagnosis which include external clinical signs, internal clinical signs and microscopic observations are selected. When a user selects the observed signs of olive flounder from the listed options, the program provides maximum 5 presumed disease candidates in order. The disease information, treatment and prevention methods are provided by connected web server through internet. The program would support fish doctors and farmers by providing easy and rapid diagnosis of diseased olive flounder.

• 한국어병학회지
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• 제27권2호
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• pp.85-89
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• 2014

Water temperature is a key environmental factor controlling the epizootics of viral diseases in fish. High water temperature is associated with the rapid spread of rock bream iridovirus (RBIV) disease and with high mortality of RBIV infected fish. Although protection of fish against iridoviral disease by active immunization has been reported, little information is available concerning whether fish survived from an epizootic of iridoviral disease can naturally acquire resistance against the viral disease. In the present study, we have demonstrated that juvenile rock bream, which survived from a natural epizootic of RBIV, acquired resistance against recurrence or reinfection of RBIV, and this resistance was established during the subsequent low water temperature period. Furthermore, the possible involvement of the adaptive humoral immune response in the resistance of the juvenile rock bream was suggested by in vivo neutralization experiment.

• 한국어병학회지
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• 제37권1호
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• pp.155-158
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• 2024

A blood parrot (Amphilophus citrinellus × Vieja melanurus) cichlid showing a flared left operculum was sent to the Fish Disease Clinic. The fish showed intermittently irregular ventilation and reddish soft swellings located at the ventral part of the left branchial cavity for one month. Other abnormal symptoms were not observed, and the appetite was normal. Only a putative diagnosis was conducted based on the history taking and external symptoms because the owner did not want an invasive biopsy or other potentially stressful examination of the fish. Therefore, considering the information available and the treatability, goiter (thyroid hyperplasia) was suspected as the top differential diagnosis, and the empirical treatment of administering iodide (0.03~0.015ppm) in environmental water was conducted. The treatment was discontinued for six months because the swelling was noticeably reduced. Body color became pale, but other abnormal signs were not observed.

• 한국정보통신학회논문지
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• 제14권1호
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• pp.145-155
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• 2010

본 연구는 키워드 기반의 단순 검색이 아닌 개념의 관계와 추론을 통해 연관정보 및 계층 정보를 함께 보여 줄 수 있는 수산용의약품 도메인 온톨로지 구축 방안을 제안한다. 이를 위해 수산분야 종사자들로부터 적합성질문 목록을 조사하여 개념 및 용어를 도출하는 선행과정을 수행한다. 다음으로 온톨로지 언어인 OWL을 지원하는 Protege-OWL 편집기를 이용하여 온톨로지 모델링 과정을 기술한다. 그리고 마지막으로 구축된 온톨로지를 통해 사용자들이 수산용의약품에 대한 관련 정보를 쉽게 찾아갈 수 있는 사용자 인터페이스를 제안한다. 이는 수산용의약품과 연관된 질병, 어종, 약품평가 내역을 다른 위치로 이동하지 않고 한 화면 내에서 확인 할 수 있게 됨으로써 관련 전공학생, 수산질병관리사, 양식어민들에게 필요한 정보에 대한 효과적인 검색 방법을 제공한다.

• 한국수산과학회지
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• 제46권5호
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• pp.582-588
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• 2013

The impact of global warming on aquatic systems has been a priority research area in the past decade. However, the possibility that increased temperatures will cause shifts in viral disease outbreaks has not been well addressed. In the present study, with increasing water temperature (WT) in the coastal area of Korea, we estimated the possibility of changes in fish viral diseases. From the present time, WT may rise between 0.62 and $1.7^{\circ}C$ by 2050, and the effect on aquaculture could be more adverse than benefitial. Red seabream iridovirus disease (RSIVD) and viral nervous necrosis (VNN) cause high mortality above 22 and $24^{\circ}C$, respectively, and outbreaks could commence earlier and persist for prolonged periods. Nevertheless, the period of occurrence of viral hemorrhagic septicemia (VHS), which outbreaks at a lower WT (< $18^{\circ}C$), could be shorter than the current infectious period. Thermal stress in fish causes reductions in growth and immunocompetence; thus, increases in summer WT can lead to the development of new viral diseases. WT has a strong influence on fish population dynamics; therefore, entry of new viruses and changes in the prevalence of infection can be expected if carrier fishes are introduced or migrate to Korean waters.

• 환경생물
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• 제37권4호
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• pp.474-482
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• 2019

자연수계 수산생물의 전염병 모니터링은 자연수계 및 양식 수산생물의 질병 관련성 및 상관관계 구명은 질병 발생 예방 및 확산 방지에 매우 중요한 역할을 한다. 2018년 해구 64개소에서 어류 39종 977마리 및 갑각류 14종 287마리를 선정하여 총 1,264마리에 대하여 병원체 감염 여부를 조사하였다. 어류는 법정전염병 2종(VHS, RSIVD) 및 비법정전염병 3종(MABVD, HRVD, LCD)을 분석하고 갑각류는 법정전염병 6종(WSD, IHHN, TS, IMN, YHD, WTD)을 분석하였다. 조사한 모든 시료에서 전염병이 검출되지 않았지만, 우리나라에서 조사한 자연수계 수산생물이 무병하여 청정국 또는 청정지위 선언에 중요한 정보를 제공할 것이다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권8호
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• pp.2278-2291
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• 2023

Imported ornamental fish should be quarantined because they can have dangerous diseases depending on their habitat. The quarantine requires a lot of time because quarantine officers collect various information on the imported ornamental fish. Inefficient quarantine processes reduce its work efficiency and accuracy. Also, long-time quarantine causes the death of environmentally sensitive ornamental fish and huge financial losses. To improve existing quarantine systems, information on ornamental fish was collected and structured, and a server was established to develop quarantine performance support software equipped with a text search engine. However, the long names of ornamental fish in general can cause many typos and time bottlenecks when we type search words for the target fish information. Therefore, we need a technique that can correct typos. Typical typo character calibration compares input text with all characters in a calibrated candidate text dictionary. However, this approach requires computational power proportional to the number of typos, resulting in slow processing time and low calibration accuracy performance. Therefore, to improve the calibration accuracy of characters, we propose a fusion system of simple Artificial Neural Network (ANN) models and character preprocessing methods that accelerate the process by minimizing the computation of the models. We also propose a typo character generation method used for training the ANN models. Simulation results show that the proposed typo character correction system is about 6 times faster than the conventional method and has 10% higher accuracy.

• 한국정보통신학회논문지
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• 제16권3호
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• pp.626-634
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• 2012

양식 환경의 과학적이고 체계적인 관리와 양식어민을 위해 실시간 수질 및 급이 정보 이외에도 자료의 종합적인 판단과 변화 이력을 확인하고 관리할 수 있는 시스템이 필요하다. 따라서 본 연구에서는 양식장의 수질, 급이의 현재 상태를 제시하고 이력 정보를 기반으로 시뮬레이션 가능하며 상태 변화를 단계 별로 확인 가능한 시스템을 비주얼 C++를 이용하여 구현하였다. 또한 수질, 급이 상태 정보를 수산지식을 기반으로 종합적으로 분석할 수 있고 제시할 수 있는 엔트로피 모델을 제안하였다. 이는 추후 질병 및 다양한 연구 결과를 반영한 고차원의 양식 환경 모델을 생성할 수 있는 토대가 될 수 있다.

• BMB Reports
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• 제46권2호
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• pp.65-72
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• 2013

In situ detection of RNAs is becoming increasingly important for analysis of gene expression within and between intact cells in tissues. International genomics efforts are now cataloging patterns of RNA transcription that play roles in cell function, differentiation, and disease formation, and they are demon-strating the importance of coding and noncoding RNA transcripts in these processes. However, these techniques typically provide ensemble averages of transcription across many cells. In situ hybridization-based analysis methods complement these studies by providing information about how expression levels change between cells within normal and diseased tissues, and they provide information about the localization of transcripts within cells, which is important in understanding mechanisms of gene regulation. Multi-color, single-molecule fluorescence in situ hybridization (smFISH) is particularly useful since it enables analysis of several different transcripts simultaneously. Combining smFISH with immunofluorescent protein detection provides additional information about the association between transcription level, cellular localization, and protein expression in individual cells.