• Journal of Korean Society on Water Environment
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• v.33 no.1
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• pp.97-106
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• 2017

In this study, the characteristics of nonpoint source pollutant loads from separate sewer overflow (SSO) and combined sewer overflow (CSO) were evaluated during 2016 in Namyangju city, Korea. Five rainfall events were monitored during 2016 with ranging from 14.5 mm to 121.5 mm. The runoff ratio of CSO was higher than that of SSO because only design volume of maximum sanitary sewer ($1Q_h$) was transported and treated and $2Q_h$ was overflowed to waterbody during rainy day although combined sewer system was designed to transport $3Q_h$ to treatment system. The event mean concentrations (EMCs) and pollutant loads from CSO were higher than those from SSO. BOD and COD of CSO, and TOC and TN of SSO represented distinct first flush phenomena. The inadequate management in combined sewer system from which the untreated $2Q_h$ from CSO was overflowed to waterbody during rainy day could influence on high pollutant loads and first flushing. Treating $2Q_h$ from CSO, source control such as low impact development, and treating outflow from SSO were strongly recommended to control non-point source pollution in urban area.

• Korean Journal of Ecology and Environment
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• v.45 no.4
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• pp.459-473
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• 2012

This study evaluated the rainfall-runoff characteristics of Non-point Pollution Source (NPS) of the impervious area through on-site monitoring. In this study, trend analysis was performed by various runoff analysis method of non-point pollution source. The characteristics of rainfall at impervious area appeared to be influenced by rainfall strength. It is judged that the measure is required to be prepared against that now that concentration difference of non-point pollution source appeared to be big by precedent number of days of no rainfall. However, it appeared that Rainfall Sustaining Time (RST) has nothing to do with effluent concentration of non-point pollution source, however, the rising tendency that effluent concentration did not appear because the tendency that concentration of non-point pollution source reduces more than 50% within initial 60 min due to first flushing effects and rainfall sustaining time is long. If looking into the outflow tendency of non-point pollution source at the impervious area, it showed the tendency that the concentration lowers gradually as time goes by after initial concentration appeared very high. However, it could be recognized that the concentration of non-point pollution source appeared to be high as the pollutants integrated on the surface of the road during dry season. The Event Mean Concentrations (EMCs) in impervious area were ranged $9.2{\sim}199.3mg{\cdot}L^{-1}$ for TSS, $8.1{\sim}24.2mg{\cdot}L^{-1}$ for $COD_{Mn}$, $0.070{\sim}1.860mg{\cdot}L^{-1}$ for T-N. Based on such runoff characteristics of non-point pollution source, it is judged that it would be desirable to process initial rain efficiently as the measure against initial rain phenomenon at the impervious area.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.7 no.3
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• pp.415-428
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• 2000

The purpose of this study was to identify side effects of the vesicant chemotherapy. The study was designed to be a descriptive survey. The subjects of this study were 88 patients with various types of cancer, primary lung cancer(25.0%), advanced gastric cancer(25.0%), breast cancer(20.5%), etc. The mean age was 44.8 years old(range: 16-68). The questionnaire was completed by nurses of the outpatient unit and chemotherapy ward, and intravenous nurse specialist. The results of the study were as follows: 1) Chemotherapy was administered with a 23G scalp needle and 24G insyte. Injection site was dorsum of hands(64.7%), cephalic vein(19.3%). Successful rate for the first attempt was 88.6%. The first & second cycle chemotherapy was 29.5% each.. Mainly used drugs were Navelbine(34.1%), Adriamycin(20.5%). 2) Venous Problems after chemotherapy were pain(13.6%) incurred by venous, mainly due to the administration of Navelbine; redness at the inravenous site(12.5%) and itching sense 2.3% Non-venous problems were nausea (18.2%), dullness(14.8%), vomiting(8.0%), facial flushing(6.8%), anxiety(5.7%). Subjective discomforts after chemotherapy were generalized arm pain at the injection side(14.8%), dizziness(6.8%), weakness(5.7%) and general bodyache(5.7%). Systemic anaphylactic reaction and extravasation did not occur. 3) Non-venous problem after chemotherapy were nausea, vomiting & anorexia. Frequency of chemotherapy related to side effects were itching, facial flushing, and nausea(p< .05). Day of chemotherapy related to side effects were nausea & vomiting(p< .05). Site of chemotherapy related to side effects were redness(p< .05). Frequency of venipuncture related to side effects were redness(p< .05). Conclusively, cancer chemotherapy patients have had some venous problem. They need appropriate venous access devices for chemotherapy. And other non-venous problem will be managed appropriately. Further research was required to identify the rate of venous complication or side effects of vesicant chemotherapy.

• Journal of Environmental Science International
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• v.20 no.8
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• pp.977-986
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• 2011

This study analyzed the characteristics of stormwater runoff in the orchard areas and quantitatively estimated effluence of nonpoint source pollutants for the volume of runoff. Two target areas under vine cultivation were each $2,000m^2$ and $1,800m^2$, located in Gyeongju City. Since grape was the only crop on the target area, the characteristics of stormwater runoff at vineyard could be evaluated independently. A total of 51 rainfall events in the vineyard area during two years(2008-2009) was surveyed, and 19 of them became stormwater runoff, with rainfall ranging 16.5 - 79.7 mm and antecedent dry period of 1-13 days. The pollutant runoff loads by volume of stormwater runoff showed BOD ranging 19.5 - 45.3% in 30% of runoff volume. The average pollution discharge rate was 32.4%, indicating small first flush effect of BOD. The range of SS concentrations was 5 - 52.0% in 10% of runoff volume, showing the average 28.7% of discharge rate, about 3 times more than rainfall effluent. TOC and TN appeared to be similar to the results of BOD, the average discharge rate of 30.9% and 30.6% for TOC and TN, respectively, for 30% of stormwater runoff volume. Average discharge rate of COD and TP in the same runoff volume was 35.1% and 36%, respectively, showing comparatively high discharge ratio. As the targeted vineyard area was permeable land, the pollution load ratio against rainfall-runoff volume appeared to be 1:1, implying no strong first flush effect for all the survey items.

• Journal of Korean Society of Water and Wastewater
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• v.19 no.5
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• pp.547-556
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• 2005

The objective of this study is to obtain adequate intercepting flow during wet weather conditions in combined sewer system. Two study sites are selected under considering different population density, one is developed area with heavy urbanization. Another is recently developing area. In the analysis of field investigation, SS was most significant in initial flushing effects compared with other factors and showed the result with the order of COD, TP, TN. As compared with event mean concentration(EMC) of runoff, BOD, TN and TP showed high concentrations in wide area with relatively large population density. It is by the reason that much pollution load was discharged to receiving water from urbanized area during wet period. According to results of storm-water modeling, 53% of total COD and 52% of total SS pollution load were discharged to receiving water by overflow than intercepting capacity in middle population density site. Also, in the urbanized area, pollution load was discharged to receiving water by 49% of total COD and 77% of total SS. These results can be applied to setup for pollution load flow(budget) generation, collection, treatment and discharging in order to obtain adequate intercepting flow.

• Journal of Microbiology and Biotechnology
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• v.10 no.4
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• pp.496-501
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• 2000

Escherichia cole NZN111, which is known as a pfl ldhA double mutant strin, was metabolically engineered to produce succinic acid by overexpressing malic enzyme into the E. coli controlled by a trc promoter. Fermentation studies were carried out in a LB medium by first growing cells aerobically to an $OD_{600}$ of 5. At this point, 0.01 mM IPTG was added to induce the overexpression of malic enzyme and the agitation speed was gradually lowered. When the culture $OD_{600}$ reached 11, a complete anaerobic condition was achieved by flushing with a $CO_3-H_2$ gas mixture. When NZN111(pTrcML) was cultured at $37^{\circ}C$, the final succinic acid concentration of 2.8 g/l could be obtained after 30 h of anaerobic cultivation. The fermentation results were analyzed by the calculation of metabolic fluxes. Metaolic flux analysis showed that about 85% of phosphoenolpyruvate (PEP) was converted to pyruvate, and further converted to malic acid by malic enzyme.

• Journal of Korean Society for Atmospheric Environment
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• v.17 no.E2
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• pp.43-51
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• 2001

A report by the national research council in the United States suggested that many lung cancer deaths each year be associated with breathing radon in indoor air. Most of the indoor radon comes directly from soil beneath the basement of foundations. Recently, radon released from groundwater is found to contribute to the total inhalation risk from indoor air. This study presents the quantitative assessment of human exposures to radon released from the groundwater into indoor air. At first, a three-compartment model is developed to describe the transfer and distribution of radon released from groundwater in a house through showering, washing clothes, and flushing toilets. Then, to estimate a daily human exposure through inhalation of such radon for an adult. a physiologically-based pharmacokinetic(PBPK) model is developed. The use of a PBPK model for the inhaled radon could provide useful information regarding the distribution of radon among the organs of the human body. Indoor exposure patterns as input to the PBPK model are a more realistic situation associated with indoor radon pollution generated from a three-compartment model describing volatilization of radon from domestic water into household air. Combining the two models for inhaled radon in indoor air can be used to estimate a quantitative human exposure through the inhalation of indoor radon for adults based on two sets of exposure scenarios. The results obtained from the present study would help increase the quantitative understanding of risk assessment issues associated with the indoor radon released from groundwater.

• Journal of Veterinary Clinics
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• v.36 no.6
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• pp.358-363
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• 2019

An 11-year-old, female Miniature Schnauzer dog was presented with recurrent skin ulcer of the second metatarsal region in the right hindlimb following metatarsal resection. Physical examination revealed an ulcerated and bleeding lesion of the second metatarsal region in the right hindlimb. Impression smears of the ulcerative lesion confirmed numerous degenerated neutrophils and mixed bacterial infection. Initially, the dog was treated with antibiotics and povidone-iodine flushing for the control of deep pyoderma. Because the skin lesion had been deteriorated over time despite of topical and systemic treatments, skin biopsy was performed. Histopathologic examination indicated squamous cell carcinoma based on the features of multiple nests of squamous neoplastic cells and mitotic figures. Although amputation of the right hindlimb was performed, the dog was expired five months later because of tumor metastasis to the lung and the popliteal lymph node. This is the first case report describes malignant digital squamous cell carcinoma in Korea.

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.3
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• pp.89-99
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• 2021

Objectives Seborrheic dermatitis is a chronic superficial eczematous dermatitis characterized by the redness and dry or greasy squama. This case study was designed to assess the effect of Shi Wei Ba Du-San gamibang (Jeongan-tang) for seborrheic dermatitis by retrospective methods. Methods From June 1, 2016 to January 31, 2020, 5 patients with seborrheic dermatitis were treated with Jeongan-tang for 3 months at Oriental Medicine Clinic. We analyzed information and body conditions of 5 patients. Redness, squama, and skin discomfort such as itching were assessed in 5 patients by using VAS (Visual Analogue Scale) score. We evaluated the symptom change by photographs and VAS score before and after the treatment. Results At first, the frequency of flushing and redness was decreased. Secondly, the scaly skin was change to normal state and itching sensation was lessened. After the treatment, the total VAS score was decreased. Conclusions Jeongan-tang can be effective in seborrheic dermatitis, and it also can be helpful to regenerate the skin condition as well.

• Journal of The Korean Society of Clinical Toxicology
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• v.17 no.1
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• pp.1-6
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• 2019

Scombroid fish poisoning (SFP) is a form of histamine food poisoning caused by the ingestion of improperly stored fish. The term "scombroid" derives from the family name of the fish family first implicated, such as tuna and mackerel. On the other hand, non-scombroid fish species, such as sardine and herring, can also cause histamine poisoning. The histamine is converted from histidine by a bacterial enzyme in the causative fish. Because the symptoms of SFP can easily be confused with food allergies, it is believed to have been significantly under-reported. In 2016, an outbreak of SFP occurred among primary school students who had eaten yellowtail steak in Korea. The most common findings consisted of a rapid onset of flushing of the face and trunk, erythematous and urticarial rash, diarrhea, and headache occurring soon after consuming the spoiled fish. Usually, the course is self-limiting and antihistamines can be used successfully to relieve symptoms, but several life-threatening SFP cases have been reported. Clinical toxicologists should be familiar with SFP and have competency to make a differential diagnosis between fish allergy and histamine poisoning. SFP is a histamine-induced reaction caused by the ingestion of histamine-contaminated fish, whereas a fish allergy is an IgE-mediated reaction. This review discusses the epidemiology, pathophysiology, diagnosis, treatment, and preventive measures of SFP.