• 대한산업공학회지
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• 제42권2호
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• pp.122-128
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• 2016

The purpose of this study is to improve the firing elevation driving method for towed howitzer to prevent the musculoskeletal disorders. To adjust the firing elevation, it is required to rotate the hand wheel and this work has been done manually in the firing test range as the same method as field artillery troops. In the firing test range, the motor-driven firing elevation adjustment device was developed to improve the working efficiency and safety. These were compared by using posture classification scheme of RULA and REBA. It was measured elapsed time to investigate the improved operational efficiency. The optimal posture of upper body to operate the hand wheel for field artillery troops was proposed.

• 대한안전경영과학회지
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• 제6권2호
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• pp.23-33
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• 2004

Domestic city gas is supplying in an about 10 million household on present 34 city gas companies because is begun to supply regularly after two 1980 years middle. But, result that focus on city gas supply spread and stable supply for supply area and neglects about safety problem, hundreds casualties such as Ahyun explosion accident and Deagu city gas explosion accident were reached in situation that occurred large size calamity occurs it is dizzliness. In the case of advanced nation, can see that accomplish system and progress that in technology after experience major accident. Therefore, grasp problem investigating safety actual conditions for city gas institution and study about solvable plan is required this. Also, must guide reform and level elevation of a domestic company safety technology through induction and development of safety technology that is suitable in supply, domestic real condition etc. Must help in power positivity that is full text executing high-quality safety education about step High firing mechanism safety technology than present safety education.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2004년도 춘계학술대회
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• pp.5-8
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• 2004

Domestic city gas is supplying in an about 10 million household on present 34 city gas companies because is begun to supply regularly after two 1980 years middle. But, result that focus on city gas supply spread and stable supply for supply area and neglects about safety problem, hundreds casualties such as Ahyun explosion accident and Deagu city gas explosion accident were reached in situation that occurred large size calamity occurs it is dizzliness. In the case of advanced nation, can see that accomplish system and progress that in technology after experience major accident. Therefore, grasp problem investigating safety actual conditions for city gas institution and study about solvable plan is required this. Also, must guide reform and level elevation of a domestic company safety technology through induction and development of safety technology that is suitable in supply, domestic real condition etc. Must help in power positivity that is full text executing high-quality safety education about step High firing mechanism safety technology than present safety education.

• The Korean Journal of Physiology and Pharmacology
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• 제11권6호
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• pp.247-251
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• 2007

Changes of single unit activity of CA1 hippocampus region were investigated in anesthetized Mongolian gerbils for six days following transient ischemia. Ischemia was produced immediately before the implantation of micro-wire recording electrodes. In control animals receiving pseudo-ischemic surgery, neither spontaneous neuronal activities ($5.70{\pm}0.4Hz$) nor the number of recorded neurons per animal changed significantly for six days. Correlative firings among simultaneously recorded neurons were weak (correlation coefficient > 0.6) in the control animals. Animals subjected to ischemia exhibited a significant elevation of neural firing at post-ischemic 12 hr ($9.95{\pm}0.9Hz$) and day 1 ($8.48{\pm}0.8Hz$), but a significant depression of activity at post-ischemic day 6 ($1.84{\pm}0.3Hz$) when compared to the activities of non-ischemic control animal. Ischemia significantly (correlation coefficient > 0.6) increased correlative firings among simultaneously recorded neurons, which were prominent especially during post-ischemic days 1, 2 and 6. Although the numbers of spontaneously active neurons recorded from control group varied within normal range during the experimental period, those from ischemic group changed in post-ischemic time-dependent manner. Temporal changes of the number of cells recorded per animal between control group and ischemic group were also significantly different (p = 0.0084, t = 3.271, df = 10). Cresyl violet staining indicated significant loss of CA1 cells at post-ischemic day 7. Overall, we showed post-ischemic time-dependent, differential changes of three characteristics, including spontaneous activity, network relationship and excitability of CA1 cells, suggesting sustained neural functions. Thus, histological observation of CA1 cell death till post-ischemic day 7 may not represent actual neuronal death.

• 디자인학연구
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• 제21권
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• pp.185-194
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• 1997

건축물의 마감재료인 내장타일은 생활공간에 많은 부분에 쓰여지고 있지만 제품이 연구되고 생산되고 판매되는 과정에 대해서는 별로 많은 관심을 가지지 못했다. 생활문화의 발전과 주택의 고급화는 실내공간에서 차지하는 마감재에 많은 느낌과 관심을 가지게 되어 타일에 대한 관심도 매우 높아지게 되었다. 특히 디자인을 전공하는 디자이너들에게는 타일산업은 단지 요업분야로만 생각되어져 있어 별로 큰 관심의 대상이 아니었다. 이러한 사고의 바탕으로 본 연구는 타일산업에서 차지하는 디자인의 비중과 디자인 방향과 역할을 여러 각도에서 접근하여 우리 나라 타일산업의 발전과 미래를 제시하고자 한다.

• The Korean Journal of Physiology
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• 제18권1호
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• pp.19-35
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• 1984

Since the first report of Drury and $Szent-Gy{\ddot{o}}rgyi$ in 1929, the inhibitory influences of adenosine on the heart have repeatedly been described by many investigators. These studies have shown that adenosine and adenine nucleotides have overall depressant effects, similar to those of acetylcholine. Heart beats become slow and weak. It is also well known that adenosine is a potent endogenous coronary vasodilator. Many investigations on the working mechanisms of adenosine have been focused mainly on the effects of the coronary blood flow. However, the cellular mechanisms underlying the inhibitory action of adenosine on sinus node are not well understood yet. Thus, this study was undertaken to examine the behavior of rabbit SA node under influence of adenosine. In these series of experiments three kinds of preparations were used: whole atrial pair, left atrial strip, and isolated SA node preparations. The electrical activity of SA node was recorded with conventional glass microelectrodes 30 to 50 $M{\Omega}$. The preparations were superfused with bicarbonate-buffered Tyrode solution of pH 7.35 and aerated with a gas mixture of $3%\;CO_2-97%\;O_2$ at $35^{\circ}C$. In whole atrial pair, adenosine suppressed sinoatrial rhythm in a dose-dependent manner. Effect of adenosine on atrial rate appeared at the concentration of $10^{-5}M$ and was enhanced in parallel with the increase in adenosine concentration. Inhibitory action of adenosine on pacemaker activity was more prominent in the preparation pretreated with norepinephrine, which can steepen the slope of pacemaker potential by increasing permeability of $Ca^{+2}$. Calcium ions in perfusate slowly produced a marked change in sinoatrial rhythm. Elevation of the calcium concentration from 0.3 to 8 mM increased the atrial rate from 132 to 174 beats/min, but over 10 mM $Ca^{+2}$ decreased. The inhibitory effect of adenosine on sinoatrial rhythm developed very rapidly. Atrial rate was recovered promptly from the adenosine-induced suppression by the addition of norepinephrine, but extra $Ca^{+2}$ was less suitable to restore the suppression of atrial rate. Adenosine suppressed also atrial contractility in the same dosage range that restricted pacemaker activity, even in the reserpinized preparation. In isolated SA node preparation, spontaneous firing rate of SA node at $35^{\circ}C$(mean{\pm}SEM, n=16) was $154{\pm}3.3\;beats/min. The parameters of action potentials were: maximum diastolic potential(MDP), $-73{\pm}1.7\;mV: overshoot(OS), $9{\pm}1.4\;mV: slope of pacemaker potential(SPP), $94{\pm}3.0\;mV/sec. Adenosine suppressed the firing rate of SA node in a dose-dependent manner. This inhibitory effect appeared at the concentration of $10^{-6}M$ and was in parallel with the increase in adenosine concentration. Changes in action potential by adenosine were dose-dependent increase of MDP and decrease of SPP until $10^{-4}M$. Above this concentration, however, the amplitude of action potential decreased markedly due to the simultaneous decrease of both MDP and OS. All these effects of adenosine were not affected by pretreatment of atropine and propranolol. Lowering extra $Ca^{2+}$ irom 2 mM to 0.3 mM resulted in a marked decrease of OS and SPP, but almost no change of MDP. However, increase of perfusate $Ca^{2+}$ from 2 mM to 6 or 8 mM produced a prominent decrease of MDP and a slight increase of OS and SPP. Dipyridamole(DPM), which is known to block the adenosine transport across the cell membrane, definately potentiated the action of adenosine. The results of this experiment suggest that adenosine suppressed pacemaker activity and atrial contractility simultaneously and directly, by decreasing $Ca^{2+}-permeability$ of nodal and atrial cell membranes.