• Toxicological Research
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• v.27 no.3
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• pp.133-135
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• 2011

The FDA guidance focuses on the use of the NOAEL to establish the maximum recommended starting dose. The majority of NOAEL has been described inaccurately or incompletely in final reports for 90-days repeated dose toxicity test based on GLP (good laboratory practice) regulation. This is the most serious one of reasons for why most pharmaceutical companies targeting global markets have disregarded the final report produced from GLP facilities in Korea. The problems in deciding NOAEL reflected in the final reports are mainly due to the followings; 1) Inaccurate description or use of NOEL, NOAEL and LOAEL, 2) Insufficient and inappropriate interpretations in findings from toxicity test. This paper is intended to provide the insight into distinguishing NOAEL from NOEL and LOAEL, and into classifying findings from toxicity test. Here, the three step method is newly suggested by applying the weight-based classification to the NOEL, NOAEL and LOAEL based on the findings.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.1C
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• pp.17-25
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• 2012

CLSM (Controlled Low Strength Material) using coal ash, which has the advantages of self-leveling, self-compacting, flowability, easy re-excavation, has been developed. In this study, CLSM additionally mixed with foaming agent for structural backfill material, aimed at lightness of materials, was developed called light-weight foamed CLSM. As the basic study of this material, to determine the optimum final mixing time and dilution ratio of existing light-weight foamed CLSM, flow, slurry unit weight and unconfined compressive strength test according to each impact factor were performed at the standard mix proportion. As the results of tests, CASE N (Final mixing time 4 min, dilution ratio 2%), CASE O (Final mixing time 3 min, foam agents ratio 3%, dilution ratio 2%) were satisfied with the standard of flow test (above 20cm), slurry unit weight test (12~15 $kN/m^3$) and unconfined compressive strength test (800 kPa~1200 kPa). These results will indicate the standard optimum final mixing time and dilution ratio of light-weight foamed CLSM for structural backfill.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.8
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• pp.1178-1181
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• 2002

Records from a total of 202 crossbred pigs were classified by their ear type and coat color to examine the presence of interrelationships with growth performances. Crossbred pigs were F2 generations of full sib family out of ten Landrace sows bred by 5 Korean domestic boars. Heavily drooped ear type was predominant, 195 out of 202 pigs over the other two types (1 straight and 6 slightly drooped). Coat colors were classified as four categories, all white, all black, dominant white or dominant black. Ratio among coat color categories did not fall within Mendelian principle of independence regarding two loci involved. There was dependency between ear type and coat color. However, due to rarity of ear types other than heavy drooped, dependency comes from distribution of those rare ear types. Three least squares models to test the effect of ear type and coat colors on growth performances were analyzed. First model analyzed effects on birth weight, body weight at 3 and 6 weeks and ADG' before weaning and between 3 and 5 weeks of age. This model included sex in addition to ear type and coat color. Second model analyzed postweaning growth traits (initial weight, final weight and ADG between these periods) upon initiation of performance testing. This model included effects of sex, test group and start age (as a covariate) in addition. Third model was fit for fasted weight before slaughter and included the effects of sex, test group and age at slaughter (as a covariate). The effects of sex and ear type were not significant source of variation for all traits. Test group was a significant source of variation for all the postweaning traits. Effect of coat color was not significant until the initiation of performance testing and became significant then after. Least squares means of dominantly black pigs were significantly lower than the other three coat colored pigs in final weight around 195 days of age and in ADG from the start of performance test and final weight measure.

• Journal of Environmental Health Sciences
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• v.27 no.2
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• pp.92-99
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• 2001

This present study was aimed to investigate the characteristics of dissoloved organic matter (DOC) in sewage. The results are summarized as follows ; The plateaux reached in 3~4 days by the biodegradability test on sewage samples based on DOC. 쏭 rations of BDOC to DOC were 48, 21, 13 and 11% for raw sewage, primary treatment effluent, secondary treatment effluent and final treatment effluent, respectively. As the SUVA values ranged less 3L/m.mg for the effluent of sewage treatment plant, the DOC is composed largely of non-humic materials, hydrophilic, less aromatic as compared to waters with higher SUVA values. Through the biodegradability test, Dissolved organics showed that the quantity of LMW(Low Molecular Weight) less than 1,000 daltons was decreased, HMW(High Molecular Weight) more than 30,000 daltons had a tendency to increase. Large portion of UV$^{254}$ in final treatment effluent was increased of MMW(Medium Molecular Weight). Also, average removal efficiency of DOC was 32% during sewage treatment.

• Women's Health Nursing
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• v.15 no.2
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• pp.121-129
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• 2009

Purpose: The purpose of this study was to examine the effect of the yoga during pregnancy on the maternal weight, delivery experience and infant birth weight. Method: The nonequivalent control group pre test-post test design was used. The participants were the healthy pregnant women, whose pre-pregnancy BMI was normal, gestational period was more than 20 weeks. The final sample consisted of 21 mother-infant dyads for experimental group and 20 dyads for control group and who agreed to participate in this study. Data were collected from February I st to December 15th, 2006. The Qi exercise prenatal program was carried out for 90 minutes a day, 2 times a week for 12 weeks. The data were analyzed using SPSS 16.0 Program. Result: The degree of maternal weight gain(p<.001), labor pain(p<.001), discomfort after delivery(p<.001) and infant's birth weight(p<.00I) were significantly different between two groups. Conclusion: The yoga during pregnancy managed weight gain of mothers. Therefore, this study suggests that yoga during pregnancy to promotes stabilization can be beneficial for maintaining healthy weight, decreasing labor pain and discomfort after delivery for pregnant women and increasing infant's birth weight.

• Korean Journal of Agricultural Science
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• v.40 no.4
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• pp.347-351
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• 2013

This study was conducted to estimate the effect of sex, breed and on the basis of the records on 300 pigs of Duroc, Landrace and Yorkshire breeds raised at the National Institute of Animal Science. Yorkshire was observed to be superior to other breeds between 90 to 110 kg of body weight. Thicker backfat was estimated in the B-mode than in A-mode of 110 kgs range than in 90 kgs. Loin eye muscle area was larger in the final weight of 110kg than in 90 and the Duroc had significantly (p<0.05) larger loin eye muscle area than other breeds. Thinner backfat was observed in males than in females in both modes of backfat measurements and in both of the final weights of test. Females had significantly larger loin eye muscle area than males, and the difference between the two sexes were larger in the final weight of 110 kg than in 90 kg. Analysis models concluded that backfat thickness certainly influences the body weight gain when at 90 kgs and 110 kgs analysed with A-mode and B-mode respectively.

• Physical Therapy Korea
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• v.21 no.1
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• pp.37-46
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• 2014

Asymmetric sitting posture may cause asymmetric buttock pressure and unilateral low back pain (LBP). The purpose of this study was to compare the differences of buttock pressure between both sides, and pelvic angle (sagittal and coronal planes) during typing in a sitting position on a pressure mat (Baltube) in individuals with and without unilateral LBP. Ten subjects with unilateral LBP and ten subjects without unilateral LBP were recruited for this study. Buttock pressure was measured using a pressure mat and pelvic angles were measured using a palpation meter. The subjects performed typing in a sitting posture for 30 minutes. Pressure data were collected and averaged at initial term (from start to first minutes) and final term (last minutes of 30 minutes). Angles of pelvic tilting were measured after 30 minutes typing. Pressure asymmetry values (difference in pressure between both sides) were calculated at the initial and final terms. A two-way analysis of variance was used to compare the differences between the initial and final pressure asymmetry values in subjects with and without unilateral LBP. An independent t-test was applied to compare the pelvic tilt angles between the two groups. To compare the change of pressure from the initial term to the final term between the symptomatic and asymptomatic sides in the unilateral LBP group, a paired t-test was applied. In the unilateral LBP group, the pressure asymmetric value at the final term was significantly greater than that of the initial term (p<.05). The angle of pelvic tilting in coronal plane was significantly greater in the unilateral back pain group compared to the without unilateral LBP group (p<.05), however, there was no significant difference in the angle of pelvic tilting in the sagittal plane between the two groups (p>.05). In the unilateral LBP group, the change of pressure from the initial term to the final term was significantly less in the symptomatic side (-6.90 mmHg) than the asymptomatic side (5.10 mmHg). This asymmetric sitting posture may contribute to unilateral LBP in the sitting position. Further studies are needed to determine if asymmetric weight bearing in sitting causes unilateral LBP or if unilateral back pain causes asymmetric weight bearing, and if the correction of asymmetric weight bearing in sitting can reduce unilateral LBP.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.2 s.257
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• pp.269-276
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• 2007

Optimal thickness and shape of the pedal arm of an automotive clutch is determined, using the numerical optimization technique, by solving the size and shape optimization problems to minimize its weight. For the optimization problems, two cases of stress and displacement constraints are considered: one from the vertical, and the other from the transverse stiffness test condition. The result of the transverse case is shown to be more conservative than that from the vertical case, being determined as the final optimum.

• Aerospace Engineering and Technology
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• v.12 no.2
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• pp.186-192
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• 2013

Fabrication of human powered aircraft and flight test procedure for pilot training are included in this paper. To meet the weight requirement, very light materials such as carbon fiber and PVC foam are used and the final weight was 41.5kg. Ninety two times of flight test were done at Goheung Aviation Test Center from August to September 2012. When KARI were lack of know-how about human powered aircraft, damages on the aircraft were very frequent. After knowing how to fly and to control, one of two pilots was finally successful in flying further to 240m in the Human Powered Aircraft Contest.

• Child Health Nursing Research
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• v.12 no.3
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• pp.359-367
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• 2006

Purpose: This study was to verify the effects of infant massage on weight recovery from physiologic weight loss, physical development of infants, and identity of their mothers. Method: A study with quasi-experimental design with time delay method was conducted from October 20, 2004 through February 20, 2005 with mothers and infants recruited from postpartum care center. 20 infants in the experimental group (once a day massage group) and 22 control group remained for the final analysis. Data were analyzed using SPSS win 11.0 program by frequency, percentage, mean, standard deviation, t-test and $X^2-test$. Results: There was no significant group difference in weight recovery from physiologic weight loss. However, experiment group showed significant increase in weight and chest circumference in 4 weeks after birth compare to the control group. For changes in behavior, experimental group showed more positive behavioral changes. The mothers who conducted massage for their infants showed higher score of identity as mothers. Conclusion: Since massage applied once a day can be still effective on physical growth of the infants, massage training program for mothers should be developed to apply easily for their infants at home. Further study is suggested to identify influencing factors on performed by mothers and identity as mothers.