• Women's Health Nursing
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• v.21 no.3
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• pp.232-240
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• 2015

Purpose: The purpose of this descriptive survey study was designed to identify the stress coping types of married immigrant pregnant women and find out the differences in maternal-fetal attachment and maternal identity based on each types. Methods: 151 married immigrant women who visited 3 women's hospitals located in J-do for pre-pregnancy checkup were selected as study objects. Data were analyzed by dsecriptive statistics, cluster analysis, t-test, ANOVA, and $Scheff{\acute{e}}$ multiple comparison test. Results: Cluster analysis revealed 4 distinct stress coping styles; low stress-coping involvement social support-oriented type, high stress-coping involvement hopeful thinking type, low stress-coping involvement type, effective stress coping types. Women frequently using effective stress coping type among the four types reported higher maternal-fetal attachment. The group of active coping styles got significantly higher score on maternal identity. Conclusion: Proper stress coping of married immigrant pregnant women regarding pregnancies proved to result in high levels of maternal-fetal attachment and maternal identity. Studies measuring the stress coping styles that affect pregnancies should be continuously conducted.

• Clinical and Experimental Pediatrics
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• v.45 no.7
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• pp.928-932
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• 2002

Perinatal atrial flutter is a potentially lethal arrhythmia. Management of this disorder is difficult and controversial. Fetal atrial flutter is a serious and life threatening rhythm disorder particulary when it causes hydrops; it may be associated with fetal death or neurological damage. Although the initial episode of flutter may be difficult to control, recurrence of atrial flutter after successful resolution of the arrhythmia seems highly unlikely and long-term prognosis is excellent. We experienced a case of a atrial flutter diagnosed in utero at $38^{+6}$ weeks' gestation by fetal cardiac echocardiography. He was treated with maternal digoxin, but he continued to have atrial flutter until delivery. Restoration of sinus rhythm occured with propafenone therapy in this patient after failure of initial digoxin therapy and direct current cardioversion.

• Journal of Embryo Transfer
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• v.30 no.4
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• pp.335-340
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• 2015

The objective of this study was to evaluate the initial detection time and development of the fetal genital structures using ultrasound in twelve pregnant small bitches. The initial detection time of the fetal genital structures was as follows: genital tubercle at days 32.6; os penis at days 45.2; labia at days 45.7; scrotum at days 47.5. Ultrasonograms of fetal genital structure according to gestational stage were as follows: Undifferentiated stage (before day 35), the genital tubercle was observed to have a small elevation and just a hyper-echogenic structure in the midline between the umbilical cord and the tail in male and female fetus. Migration stage (between day 35~45), the genital tubercle was observed as a hyper-echogenic, bilobular, oval shaped and the genital tubercle began to migrate from the initial position toward the umbilical cord in males, and toward the tail in females. Differentiated stage (after day 46), the penis and os penis were observed to stand out in the abdominal wall and the scrotum was observed toward the perineal region in male fetuses. The labia was detected at the base of the tail in female fetuses. These results indicate that ultrasound of fetal genital structures could be useful for fetal gender determination and a completely prepartum evaluation of the canine fetus.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.179-180
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• 1998

In this paper, we propose an algorithm to detect fetal movements using M-mode ultrasonography. To do this work automatically, we find the crosscorrelation between the current data vector of the depth direction of M-mode image and the previous one. In the crosscorrelation estimator, the variations of time lag $\tau$ at maximum crosscorrelation value means fetal movements. A woman in the 37th week of pregnancy was monitored and the ultrasonic image of fetus was recorded over 20-minute period to detect fetal movements using B-mode and M-mode ultrasonography simultaneously. And the presented method was compared with maternal perception and B-mode ultrasonography observed by clinician. The maternal perception method detected only 57% of all fetal movements observed by clinician. The detection of the presented method corresponds to the clinician's detection result.

• Clinical and Experimental Pediatrics
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• v.45 no.10
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• pp.1288-1291
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• 2002

Fetal valproate syndrome has been described as a distinctive pattern of minor anomalies of the face and digits. This pattern has not been delineated completely but appears to involve brachycephaly with a high forehead, shallow orbit, ocular hypertelorism, small nose, small mouth, low set posteriorly rotated ears, long overlapping fingers and toes, and hyperconvex fingernail. Cleft palate and congenital heart disease have occasionally been described in babies exposed to valproate during embryogenesis. We report a neonate born from an epileptic mother receiving sodium valproate during pregnancy. This neonate presented with characteristic facial abnormalities, both elbow contractures, and overlapping of right first and second toe, forth and fifth toe, and left first and second toe. This case raises the possibility that these abnormal appearances might be caused by intrauterine valproate exposure.

• Journal of Korean Academy of Nursing
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• v.40 no.4
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• pp.571-579
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• 2010

Purpose: The purpose of this study was to explore the effects of a taegyo program on parents-fetal attachment and parenthood in first pregnancy couples (mothers and spouses). Methods: The research design was a nonequivalent control group pretest-posttest experiment. Study participants were 52 first pregnancy couples visiting two medium-scale obstetrics and gynecology clinics located in Gwangju. A total of 52 couples were assigned to the experimental group (25 couples) and the control group (27 couples). The experimental couples were provided with a taegyo program for 4 weeks. Data were analyzed by chi square test, t-test, and ANCOVA using the SPSS program. Results: Post-treatment maternal- fetal attachment, paternal-fetal attachment and motherhood significantly increased in the experimental group as compared to the control group, but post-treatment fatherhood, anxiety, blood pressure and pulse of participants in the experimental group showed no significant difference from those in the control group. Conclusion: From these results, it is suggested that the taegyo program has beneficial effects in enhancing parent-fetal attachment and motherhood in first pregnancy couples. Therefore, a taegyo program can be recommended as a nursing intervention program for first pregnancy couples.

• The Korean Journal of Legal Medicine
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• v.41 no.2
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• pp.41-45
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• 2017

Fetal DNA (fDNA) detection in maternal serum is a challenge due to low copy number and the smaller size of fDNA fragments compared to DNA fragments derived from the mother. Massively parallel sequencing (MPS) is a useful technique for fetal genetic analysis that is able to detect and quantify small amounts of DNA. In this study, seven clinical samples of maternal serum potentially containing fDNA were analyzed with a commercial single nucleotide polymorphism (SNP) panel, the HID-Ion $AmpliSeq^{TM}$ Identity Panel, and the results were compared to those from previous studies. Reference profiles for mothers and fetuses were not available, but multiple Y chromosomal SNPs were detected in two samples, indicating that fDNA was present in the serum and thereby validating observations of autosomal SNPs. This suggests that SNP-based MPS can be valuable for fDNA detection, thereby offering an insight into fetal genetic status. This technology could also be used to detect small amounts of DNA in mixed DNA samples for forensic applications.

• Journal of Korean Medical classics
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• v.32 no.2
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• pp.147-163
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• 2019

Objectives : Morning Sickness, or Nausea and Vomiting of Pregnancy(NVP) is a frequently experienced phenomenon among pregnant women whose cause is still unknown. While the key trait of this symptom is its temporality, it is hardly considered in existing studies on the cause of NVP based on Korean Medical(KM) literature. We hope to remedy this. Methods : We looked for contents on fetal development in Korean Medical literature from the Siku Quanshu as well as other key literature of KM and examined the results together with contents on NVP to find any correlation. Results : We found that the beginning stages, namely the third month marked a significant change in the course of fetal development where the fetus's own Shen(神) is first developed by work of the mother's Heart(心). In other words, the third month is when the mother's and child's Shen first encounter. Conclusions : We hypothesized that NVP whose symptoms are closely linked to the functions of the Heart, is likely to be related to this event, which was supported by the common involvement of the Heart which was involved in both fetal development and NVP during the third month of pregnancy.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.203-203
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• 2002

The present study was conducted to investigate the potential embryo-fetal toxicity of 2-bromopropane(2-BP) in rats. The test agent was subcutaneously administered to pregnant rats from gestational day 6 to 19 at dose level of 0, 500, 1000, 1500 mg/kg.(omitted)

• Clinical and Experimental Pediatrics
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• v.57 no.10
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• pp.425-433
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• 2014

Adrenal and thyroid hormones are essential for the regulation of intrauterine homeostasis, and for the timely differentiation and maturation of fetal organs. These hormones play complex roles during fetal life, and are believed to underlie the cellular communication that coordinates maternal-fetal interactions. They serve to modulate the functional adaptation for extrauterine life during the perinatal period. The pathophysiology of systemic vasopressor-resistant hypotension is associated with low levels of circulating cortisol, a result of immaturity of hypothalamic-pituitary-adrenal axis in preterm infants under stress. Over the past few decades, studies in preterm infants have shown abnormal clinical findings that suggest adrenal or thyroid dysfunction, yet the criteria used to diagnose adrenal insufficiency in preterm infants continue to be arbitrary. In addition, although hypothyroidism is frequently observed in extremely low gestational age infants, the benefits of thyroid hormone replacement therapy remain controversial. Screening methods for congenital hypothyroidism or congenital adrenal hyperplasia in the preterm neonate are inconclusive. Thus, further understanding of fetal and perinatal adrenal and thyroid function will provide an insight into the management of adrenal and thyroid function in the preterm infant.