• 한국임상수의학회지
• /
• 제28권6호
• /
• pp.591-594
• /
• 2011

9개월령의 암컷 말티즈견과 1년령의 암컷 비글견이 지속성 심잡음을 주증으로 내원 하였다. 두 환축은 2차원 심초음파 및 심혈관조영술을 통해 동맥관개존증 (PDA)으로 진단되었다. 평가된 환축들의 동맥관 사이즈는 비교적 큰 편이었으며, 혈관 폐색장치 중 Amplatzer$^{(R)}$ vascular plug를 통한 동맥관의 폐쇄술이 시도 되었다. 말티즈 견의 경우, Amplatzer$^{(R)}$ vascular plug를 이용하여 동맥관의 완전폐쇄가 이루어 졌으며, 폐쇄직후 지속성 심잡음이 사라졌다. 비글견의 경우, Amplatzer$^{(R)}$ vascular plug 삽입 후 심잡음이 줄어들긴 했지만, 심혈관 조영검사에서 잔류혈류가 관찰되었다. 시술의 안전성 및 시술 후 합병증은 두 환자 모두에서 지속적으로 모니터링 되었다. 본 2 증례는, Amplatzer$^{(R)}$ vascular plug를 이용한 성공적인 동맥관개존증 폐쇄술에 대한 국내 첫 증례보고이다.

• 대한조선학회논문집
• /
• 제47권4호
• /
• pp.606-612
• /
• 2010

This study took advantage of NC processing technique in order to recreate design in development process of leisure boat based on the Korean boats and ships. CNC milling is an area which is concerned in automation process of boat production and needs sophisticated software, equipment and professionals to pilot it. The progress of manufacture begins when the surface model creation and simulation being done using CAD/CAM software. In this process, the needs such as 3D design, NC processing data, plug lamination and partition processing appear as detailed steps. The study completed these detailed steps and also the application example has been studied with presenting engineering potentialities.

• 한국임상수의학회지
• /
• 제32권3호
• /
• pp.243-246
• /
• 2015

9개월령 암컷 치와와(체중 1.5 kg)가 운동 불내성과 좌측 흉벽 심기저부의 큰 심잡음으로 의뢰되었다. 방사선 검사의 배복상에서 좌심실 종대 및 주폐동맥, 대동맥, 좌심방 확장의 전형적인 소견인 트리플범프(triple bump)가 확인 되었다. 심초음파 검사에서 동맥관이 확인되었으며 대동맥과 주폐동맥 사이에 좌우 방향의 연속적인 와류(최고 속도 5.73 m/s)가 측정되었다. 이 환자는 대퇴 정맥(정맥을 통한 접근)으로 접근하여 Amplatzer$^{(R)}$ vascular plug를 이용해 동맥관을 성공적으로 폐쇄하였다. 본 증례는 PDA를 대퇴 정맥으로 접근하여 vascular plug를 이용해 막은 국내 최초보고이다.

• 한국동물위생학회지
• /
• 제47권1호
• /
• pp.55-59
• /
• 2024

A 4-year-old, spayed female German Shepherd dog (GSD) weighing 22.4 kg was referred to Chungnam National University Veterinary Medicine Teaching Hospital with the chief complaint of a cardiac murmur. A continuous murmur was detected at the left basilar region upon auscultation. In the thoracic radiographs, slight bulging of the aorta, the main pulmonary artery, and the left atrium were observed. Echocardiography revealed continuous turbulent flow directed from the main pulmonary artery towards the pulmonary valve and consistently within the main pulmonary artery. Based on all the results, a diagnosis of type II A patent ductus arteriosus (PDA) was made, and plans were established to treat it with transcatheter occlusion. Transcatheter occlusion was performed using a vascular plug and successfully deployed at the PDA. The patient did not exhibit any complications. GSDs are relatively less common compared to small-breed dogs in South Korea. Considering that GSDs are predisposed to PDA, it is crucial to periodically assess the presence of PDA through auscultation and echocardiography, even in the absence of clinical signs. Transcatheter occlusion using a vascular plug can be an option for treatment and can yield favorable outcomes.

• Applied Microscopy
• /
• 제21권2호
• /
• pp.14-28
• /
• 1991

The present study was designed in order to clarify ultrastructural characteristies of the spermatogenetic process and to examine survival state of the spermatozoa introduced into the female reproductive tract after autumnal coitus in the Korean greater horseshoe bats(Rhinolophus ferrumeguinum korai). The general morphological characteristics of spermatogenesis were principally similar to those of the other mammalian species; acrosomal formation, flagellar formation, middle piece formation and concentration of the spermatozoan nucleus. The spermatozoa introduced into the vagina were found to be dead forming a vaginal plug, the opaque central core of which consisted of trapped dead spermatozoa. Some spermatozoa introduced into the uterus were observed to be phagocytized by the polymorphonuclear leucocytes infiltrated into the uterine glandular lumen. The oviductal epithelium, consisted of ciliated and secretory cells; the luminal surface of secretory cells were covered by a number of microvilli with well developed glycocalyx, suggesting a close relationship to nutrient (e.g. glycogen) supply for the spermatozoa during hibernation.

• 전기학회논문지P
• /
• 제58권4호
• /
• pp.541-545
• /
• 2009

This study evaluated the contact resistance, insulation resistance, withstand voltage characteristics and insertion force, etc., of the wire connector used inside an integrated LITE WAY lighting fixture developed for efficient installation. Since the connector connecting the lighting fixture's internal wires is housed, it is easily connected and separated and has a structure enabling a close-fitting connection. The temperature and time applied to the high temperature characteristics test of the connector are $105^{\circ}C$ and 16 hours, respectively. The measured contact resistance of the high temperature tested connector was 3.258 mV/A, and its measured insulation resistance was greater than $10\;G{\Omega}$ All specimens demonstrated uniform insulation characteristics, which could be seen to be in good condition. From the withstand voltage test results found before and after performing the high temperature operation test on the connector for cable connection, it was confirmed that the withstand voltage characteristics between all terminals were good. The insertion force of the connector connecting the internal wiring averaged 9.67 kgf. It was observed that the insertion force between the plug housing and the female terminal, and that between the plug housing and the male terminal, were 0.680 kgf and 1.27 kgf on average, respectively.

• Restorative Dentistry and Endodontics
• /
• 제45권4호
• /
• pp.43.1-43.9
• /
• 2020

A variety of therapeutic modalities can be used for the endodontic treatment of a traumatized tooth with internal root resorption (IRR). The authors present a case report of the successful restoration of a traumatized upper central incisor that was weakened due to severe IRR and subsequent periapical lesion formation. A 20-year-old female patient was referred to our clinic with severe internal resorption and subsequent periapical pathosis destroying the buccal bone wall. Root canal treatment had been initiated previously at another dental practice, but at that time, the patient's condition could not be managed even with several treatments. After cone-beam computed tomography imaging and proper chemomechanical cleaning, the tooth was managed with a mineral trioxide aggregate plug followed by root canal filling using short fiber-reinforced composite, known as the Bioblock technique. This report is the first documentation of the use of the Bioblock technique in the restoration of a traumatized tooth. The Bioblock technique appears to be ideal for restoring wide irregular root canals, as in cases of severe internal resorption, because it can uniquely fill out the hollow irregularities of the canal. However, further long-term clinical investigations are required to provide additional information about this new technique.

• Animal Bioscience
• /
• 제36권1호
• /
• pp.43-52
• /
• 2023

Objective: This study aimed to examine the influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on pregnancy in cytokeratin-18 (K18)-hACE2 transgenic mice. Methods: To determine the expression of hACE2 mRNA in the female reproductive tract of K18-hACE2 mice, real-time polymerase chain reaction (RT-PCR) was performed using the ovary, oviduct, uterus, umbilical cord, and placenta. SARS-CoV-2 was inoculated intranasally (30 μL/mouse, 1×10⁴ TCID₅₀/mL) to plug-checked K18-hACE2 homozygous female mice at the pre-and post-implantation stages at 2.5 days post-coitum (dpc) and 15.5 dpc, respectively. The number of implantation sites was checked at 7.5 dpc, and the number of normally born pups was investigated at 20.5 dpc. Pregnancy outcomes, including implantation and childbirth, were confirmed by comparison with the non-infected group. Tissues of infected mice were collected at 7.5 dpc and 19.5 dpc to confirm the SARS-CoV-2 infection. The infection was identified by performing RT-PCR on the infected tissues and comparing them to the non-infected tissues. Results: hACE2 mRNA expression was confirmed in the female reproductive tract of the K18-hACE2 mice. Compared to the non-infected group, no significant difference in the number of implantation sites or normally born pups was found in the infected group. SARS-CoV-2 infection was detected in the lungs but not in the female reproductive system of infected K18-hACE2 mice. Conclusion: In K18-hACE2 mice, intranasal infection with SARS-CoV-2 did not induce implantation failure, preterm labor, or miscarriage. Although the viral infection was not detected in the uterus, placenta, or fetus, the infection of the lungs could induce problems in the reproductive system. However, lung infections were not related to pregnancy outcomes.

• The Korean Journal of Physiology
• /
• 제8권1호
• /
• pp.15-22
• /
• 1974

The influence, upon male rat's mating behavior, of Korean Panax Ginseng administered for 3 and 5 days was investigated by direct behavioral observation and also by counting the number of copulation plugs the animals deposited. Four쇼-four male albino rats were used. Part of the animals received ginseng for 3 days (ginseng-3 day group, N= 12) or for 5 days(ginseng-5 day group, H=10), while the remaining animals received saline for 3 days (saline-3 day group, N=12) or for 5 days (saline-S day group, N=10). Each animal belonging to the 2 ginseng groups received subcutaneously 0.5 ml/100 g body weight of ginseng alcohol extract solution (4 mg of the ethyl alcohol extract in 1 ml of physiological saline), and each rat belonging to the 2 saline groups received the same amount of saline per day. During the dark period of the light-dark cycle on the next day following the last drug administration, a female rat in the artificial estrus was introduced to each male and the mating behavior was observed for 45 minutes. The observation session was divided into two parts and, in the early part which terminated with the first ejaculation and succeeding intromission, following behavioral measures were taken: mounting latency, intromission latency, inter-intromission period, ejaculatory latency(time from the first intromission until the first ejaculation), occurrence of mounting with intromission, occurrence of mounting without intromission, and postejaculatory interval. Behavioral measures taken in the later part of the session after the first ejaculation were: occurrence of mounting with intromission, occurrence of mounting without intromission, and occurrence of ejaculation. Immediately after the behavioral observation session the experiment turned to measure, for 10 days, the number of copulation plug which each pair of rats deposited. Following results were obtained: 1. After several mountings mounting with intromission, males of the 2 ginseng groups finished the first ejaculation significantly earlier than the corresponding 2 saline groups did. 2. The postejaculatory latency was significantly reduced in the ginseng-5 day group compare with the value of the saline-5 day group and also compared with the value of the ginseng-3 day group. 3. The 2 ginseng groups ejaculated significantly more often in 45 minutes' observation session than the corresponding 2 saline groups did. 4. The number of copulation plug deposited in 10 days by the animals of the 2 ginseng groups. significantly exceeded the number deposited by the corresponding 2 saline group animals. The animals of the ginseng-5 day group deposited copulation plugs significantly more than the animals of the ginseng-3 day group did. It is inferred from the above results that the ginseng facilitates mating behavior of male rats, and that the degree of facilitation may be influenced by the duration of drug administration.

• Journal of Chest Surgery
• /
• 제30권11호
• /
• pp.1117-1120
• /
• 1997

충남대학교병원에서 1980년7월부터 1995년 8월까지 경험한 식도이물 10례를 수술 치료하였다. 나이는 25 세에서 71세로, 평균 나이는 45.3세였고 남녀의 비는 6:4였다 가장 흔한 증상은 연하곤란, 발열, 이물감, 경부 동통이였다. 이물질은 생선뼈 3례였고, 거품 약포장지가 2례였고, 맥주병 마개,욕조 물마개, 깨진 사발 조각, 닭고기, 콩이 각각 1례였다. 진단은 수용성 식도 조영제와 식도 내시경을 이용하였다. 10례중 2례에서는 과거에 가성소다 섭취로 인해 식도 협착이 있었다. 1례에서는 정신과적 문제가 있었다. 식도이물은 모두 수술적 처치로 제거하였다 5례에서는 경부식도절게술을 시행하였고 1례는 우측 개흉술 을, 1례는 개복하여 위를 통해 위관을 역류성으로 통과 제거하였으며, 2례는 경부농양이 있어 절개후 배농하 였다. 3례는 수술 후 누출이 있었으나 수술치료없이 보존적 요법으로 호전되었으며,1례는 일시적인 애성이 있 었다. 1례는 외상성 기흉이 발생하여 폐쇄적 홉관 삽관술로 치료하였다. 수술 사망자는 없었다.