• 한국발생생물학회지:발생과생식
• /
• 제22권3호
• /
• pp.289-295
• /
• 2018

Large quantity of eggs fail to be fertilized and many of fertilized eggs are unable to hatch in the eel, Anguilla japonica. Larvae of eel absorb egg yolk up to 8 days after hatching but the majority of hatched larvae die before they reach the stage of first feeding in this species. Genes of key enzymes for yolk processing (cathepsin B, D, L and lipoprotein lipase - abbreviated as ctsb, ctsd, ctsl and lpl, respectively) could be associated with egg quality. In this study, we investigated differences in the expression of these genes between floating eggs and sinking eggs, and also the relationship between the gene expressions of the enzymes and fertilization rates in the fertilized eggs obtained from artificially matured female eels. Expressions of yolk processing enzyme genes did not show significant difference between floating and sinking egg groups. Expression of ctsb decreased when fertilization rate was high. Expression of ctsd, ctsl and lpl, however, did not show any significant differences. These results suggest that ctsb expression could be an indicator of egg quality, and that some proteins prone to be digested by ctsb could be very important in the process of fertilization and normal cleavage in this species. Further study should identify these critical proteins to improve our understanding on the quality of fish eggs.

• 한국수산과학회지
• /
• 제44권3호
• /
• pp.276-283
• /
• 2011

The growth and tolerance for water temperature and salinity were compared among red sea bream Pagrus major (RSB) black sea bream Acanthopagrus schregeli (BSB) and their hybrid ($F_1$), female RSB ${\times}$ male BSB. The growth of the $F_1$ fish did not differ until 27 days after hatching (dAH), after which the most rapid growth was observed until approximately 300 dAH, followed by RSB and BSB. However, the RSB had out grown the $F_1$ fish by approximately 303 dAH. By 480 dAH, the RSB were largest, followed by the $F_1$ and BSB groups. The tolerances for high and low water temperature were significantly different for each species and growth stage. The largest tolerance spectrum was observed in the BSB group, and the tolerance spectrums gradually decreased with increasing final body weight. During the salinity tolerance trials, all of the species started to die following transfer into freshwater (0 psu). BSB showed the highest survival rate when kept in fresh water for an average of 29.9 hours, while the $F_1$ fish were more tolerant than the RSB fish. The fish were increasingly tolerant to fresh water and changes in water temperature as they grew, while the size of the temperature spectrum remained unchanged but shifted to a lower temperature range with growth. Our results demonstrate that $F_1$ performed well in terms of growth compared to parental fish, with higher temperature and salinity tolerances than RSB, and is thus suggested to be a suitable aquaculture species for Korea and northeast China.

• 국제학술발표논문집
• /
• The 9th International Conference on Construction Engineering and Project Management
• /
• pp.1242-1242
• /
• 2022

Annually, several construction workers fall ill, are injured, or die due to heat-related exposure. The prevalence of work-related heat illness may rise and become an issue for workers operating in temperate climates, given the increase in frequency and intensity of heatwaves in the US. An increase in temperature negatively impacts physical exertion levels and mental state, thereby increasing the potential of accidents on the job site. To reduce the impact of heat stress on workers, it is critical to develop and implement measures for monitoring physical exertion levels and mental state in hot conditions. For this, limited studies have evaluated the utility of wearable biosensors in measuring physical exertion and mental workload in hot conditions. In addition, most studies focus solely on male participants, with little to no reference to female workers who may be exposed to greater heat stress risk. Therefore, this study aims to develop a process for objective and continuous assessment of worker physical exertion and mental workload using wearable biosensors. Physiological data were collected from eight (four male and four female) participants performing a simulated drilling task at 92oF and about 50% humidity level. After removing signal artifacts from the data using multiple filtering processes, the data was compared to a perceived muscle exertion scale and mental workload scale. Results indicate that biosensors' features can effectively detect the change in worker physical and mental state in hot conditions. Therefore, wearable biosensors provide a feasible and effective opportunity to continuously assess worker physical exertion and mental workload.

• Clinical and Experimental Reproductive Medicine
• /
• 제46권4호
• /
• pp.206-210
• /
• 2019

Mucopolysaccharidosis type II (MPS II) is a rare X-linked recessive lysosomal storage disease caused by mutation of the iduronate-2-sulfatase gene. The mutation results in iduronate-2-sulfatase deficiency, which causes the progressive accumulation of heparan sulfate and dermatan sulfate in cellular lysosomes. The phenotype, age of onset, and symptoms of MPS II vary; accordingly, the disease can be classified into either the early-onset type or the late-onset type, depending on the age of onset and the severity of the symptoms. In patients with severe MPS II, symptoms typically first appear between 2 and 5 years of age. Patients with severe MPS II usually die in the second decade of life although some patients with less severe disease have survived into their fifth or sixth decade. Here, we report the establishment of a preimplantation genetic diagnosis (PGD) strategy using multiplex nested polymerase chain reaction, direct sequencing, and linkage analysis. Unaffected embryos were selected via the diagnosis of a single blastomere, and a healthy boy was delivered by a female carrier of MPS II. This is the first successful application of PGD in a patient with MPS II in Korea.

• 한국소성가공학회:학술대회논문집
• /
• 한국소성가공학회 2002년도 춘계학술대회 논문집
• /
• pp.29-32
• /
• 2002

The mechanical joining process of a sheet metal pair has been developed in order to replace the resistance spot welding process in case that joining of mechanically unweldable materials and coated sheet metals with different thickness are needed. Form-joining or clinching, a kind of mechanical joining process, is defined as joining process of a sheet metal pair by geometric constraint imposed by plastic deformation of workpieces without any additive part. It has been reported that the joining strength by commercial form-joining apparatus is 50∼70 percent of that by resistance spot welding. Therefore, a two-step form-joining process with a secondary punch is proposed. The device is designed to improve the joining strength by increasing the geometric constraint of the deformed shape by combining a primary punch, a secondary punch and a female die. In order to verify the improved joining strength by the designed process, the tensile-shear strength, the peel-tension strength and the asymmetric peel-tension strength are compared with those by the TOX process and resistance spot welding.

• The Korean Journal of Pain
• /
• 제10권2호
• /
• pp.301-303
• /
• 1997

A 35-year-old female patient was referred to our hospital with neurologic symptoms after continuous epidural block performed 2 days earlier. She die not have any prior no previous lumbar surgery or experience trauma, intraspinal hemorrhage, infections or other known causative factors to associate with neurologic symptoms. Continuous epidural block is widely used for postoperative pain control. Complications can occur with this block including postduralpuncture headache, epidural abscess and rare cases of arachnoiditis etc. We experienced such a case of spinal arachnoiditis after continuous epidural block. Neurologic examination revealed painful bilateral hypoesthesia below $S_2$ level dermatomes, urinary and fecal incontinence and various degrees of leg weakness. The following day, the patient was noted to have bilateral sacral radiculopathies and lesion on proximal portion of both tibial nerve. CSF study reported: protein 264 mg/dl, sugar 64 mg/dl, WBC $7/mm^3$. L-spine MyeloCTscan results were unremarkable. She was discharged after a month of hospitalization and has regular checkups but her neurologic symptoms show no signs of improvement.

• 공학교육연구
• /
• 제17권5호
• /
• pp.8-12
• /
• 2014

Women in engineering subject were developed for women included engineering education in Korea. Women in the predominantly male-oriented college of engineering which is afflicted by the high dropout rate and the low employment rate of coeds in their majoring fields because of the die-hard male dominant culture. In order to resolve the related problems, Our University has been actively engaged in a movement called "Women into Engineering" (WIE) to raise the gender cognitive awareness and to train women engineers for highly qualified work force. As part of the movement, a subject called "Women in Engineering" that focuses on the gender cognitive perspective is effective to reduce the dropout rate and to land a job inside their fields by stimulating their interest in their specialty made soft/hard skills. The study was conducted a survey of the coeds who have completed the "Women in Engineering" course to evaluate the degree of satisfaction perceived, and a t-test through comparing the group of the coeds and a group of coeds who have not taken the course. The results showed statistically significant responses indicating that both groups of coeds would like to see WIE offer more basic engineering courses like "Women in Engineering." This may lay the foundation to offer other major engineering courses for juniors and seniors that emphasize the gender cognitive approach.

• 보건행정학회지
• /
• 제27권2호
• /
• pp.167-176
• /
• 2017

Background: This study aimed to analyze the impact of community health care resources on the place of death of older adults with dementia compared to those with cancer in South Korea, using public administrative big data. Methods: Based on a literature review, we selected person- and community-level variables that can affect older people's decisions about where to die. Data on place-of-death and person-level attributes were obtained from the 2013 death certification micro data from Statistics Korea. Data on the population and economic and health care resources in the community where the older deceased resided were obtained from various open public administrative big data including databases on the local tax and resident population statistics, health care resources and infrastructure statistics, and long-term care (LTC) insurance statistics. Community-level data were linked to the death certificate micro data through the town (si-gun-gu) code of the residence of the deceased. Multi-level logistic regression models were used to simultaneously estimate the impacts of community as well as individual-level factors on the place of death. Results: In both the dementia (76.1%) and cancer (87.1%) decedent groups, most older people died in the hospital. Among the older deceased with dementia, hospital death was less likely to occur when the older person resided in a community with a higher supply of LTC facility beds, but hospital death was more likely to occur in communities with a higher supply of LTC hospital beds. Similarly, among the cancer group, the likelihood of a hospital death was significantly lower in communities with a higher supply of LTC facility beds, but was higher in communities with a higher supply of acute care hospital beds. As for individual-level factors, being female and having no spouse were associated with the likelihood of hospital death among older people with dementia. Conclusion: More than three in four older people with dementia die in the hospital, while home is reported to be the place of death preferred by Koreans. To decrease this gap, an increase in the supply of end-of-life (EOL) care at home and in community-based service settings is necessary. EOL care should also be incorporated as an essential part of LTC. Changes in the perception of EOL care by older people and their families are also critical in their decisions about the place of death, and should be supported by public education and other related non-medical, social approaches.

• 한국가축번식학회지
• /
• 제16권4호
• /
• pp.353-361
• /
• 1993

This study was taken to examine external changes, behavioral changes, and endocrine changes such as estradiol-17$\beta$, progesterone, T4 and T3 of female Oreochromis niloticus living in 0$\textperthousand$, 10$\textperthousand$, 20$\textperthousand$, and 30$\textperthousand$ salt concentrations, respectively. The results obtained in these experiments were summarized as follows. In seawater obtained in these experiments were summarized as follows. In seawater challenge test, any fish didn't die in each group such as 10$\textperthousand$, 20$\textperthousand$ and 30$\textperthousand$. When fish were adapted from 0$\textperthousand$ to 10$\textperthousand$, 20$\textperthousand$ and 30$\textperthousand$, external body color of fish changed from dark-striped to light-grey color. At the same time, thyroxine and triiodothyronine concentrations significantly(P<0.05) increased, and then were at the highest level in 30 salinity. When fish were adapted from 0$\textperthousand$ to 10$\textperthousand$, feed intake of fish started from the fourth day. From 0$\textperthousand$ to 10$\textperthousand$, 20$\textperthousand$ and 30$\textperthousand$, estradiol-17$\beta$ levels were increased gradually. When fish was adapted from 0$\textperthousand$ to 10$\textperthousand$, 20$\textperthousand$ and 30$\textperthousand$, the levels of each progesterone didn't show significant change, and especially showed the lowest peak in 20$\textperthousand$. The greatest thyroxine activity(T4) was observed in 30$\textperthousand$. The levels of and triiodothyronine(T3) significantly changed in all salinities, and its level was at the highest peak in 30$\textperthousand$ salinity. Correlation coefficients between serum progesterone and triiodothyronine in 10$\textperthousand$ and 30$\textperthousand$ were ＋0.677 and ＋0.843, respectively. Correlation coefficient of serum thyroxine(T4) and triiodothyronine(T3) individuals in 10$\textperthousand$ was ＋0.768, and ＋0.843, respectively.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권1호
• /
• pp.349-353
• /
• 2014

Background: Although previously studies have reported that most patients with malignancy prefer to die at home, this is not the real situation in clinical practice. Aim: In this study, we aimed to determine the characteristics of Turkish cancer patients admitted to the emergency department (ED) within one month before death. Materials and Method: This descriptive retrospective study focused on questions about how often and why patients with cancer visited the ED before death. A total of 107 individuals with cancer were divided into 2 groups: Group 1, patients with at least one visit in the final 4 weeks; and Group 2, patients with no visit to ED. Demographic and clinical features were compared between the two groups. Statistical analyses: Descriptive statistical methods, statistical analysis for correlation, Student's t-test, chi-square tests and logistic regression were used. Results: At least one visit to ED within one month before death was reported for 64 (60%) of the 107 cases. Of these 64 (Group 1), 38% (n=24) were discharged and 9% (n=6) died in the ED. The most common site of the primary tumor was the lung (n=24, 38%) and the most common symptom was dyspnea (92%). With the other 43 (40%) cancer patients not presenting to the ED within one month before death, they were more likely to be female with another type of cancer. Conclusions: Guidelines are needed for better management of cancer patients benefiting from visits to ED within the last month of life.