• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제12권7호
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• pp.303-314
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• 2023

음성 변환(Voice Conversion)은 개인의 음성 데이터를 다른 사람의 음향적 특성(음조, 리듬, 성별 등)으로 재생성할 수 있는 기술로, 교육, 의사소통, 엔터테인먼트 등 다양한 분야에서 활용되고 있다. 본 논문은 StarGAN-VC 모델을 기반으로 한 접근 방식을 제안하여, 병렬 발화(Utterance) 없이도 현실적인 음성을 생성할 수 있다. 고정된 원본(source) 및 목표(target)화자 정보의 원핫 벡터(One-hot vector)를 이용하는 기존 StarGAN-VC 모델의 제약을 극복하기 위해, 본 논문에서는 사전 훈련된 Rawnet3를 사용하여 목표화자의 특징 벡터를 추출한다. 이를 통해 음성 변환은 직접적인 화자 간 매핑 없이 잠재 공간(latent space)에서 이루어져 many-to-many를 넘어서 any-to-any 구조가 가능하다. 기존 StarGAN-VC 모델에서 사용된 손실함수 외에도, Wasserstein-1 거리를 사용하여 생성된 음성 세그먼트가 목표 음성의 음향적 특성과 일치하도록 보장했다. 또한, 안정적인 훈련을 위해 Two Time-Scale Update Rule (TTUR)을 사용한다. 본 논문에서 제시한 평가 지표들을 적용한 실험 결과에 따르면, 제한된 목소리 변환만이 가능한 기존 StarGAN-VC 기법 대비, 본 논문의 제안 방법을 통해 다양한 발화자에 대한 성능이 개선된 음성 변환을 제공할 수 있음을 정량적으로 확인하였다.

• 사물인터넷융복합논문지
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• 제10권2호
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• pp.1-15
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• 2024

스마트 지역사회의 구축은 지역사회의 안전을 보장하는 새로운 방법이자 중요한 조치이다. 촬영 각도로 인한 얼굴 기형 및 기타 외부 요인의 영향으로 인한 신원 인식 정확도 문제를 해결하기 위해 이 논문에서는 네트워크 모델을 구축할 때 전체 그래프 컨벌루션 모델을 설계하고, 그래프 컨벌루션 모델에 협력하여 얼굴의 핵심을 추출한다. 또한 얼굴의 핵심을 특정 규칙에 따라 핵심 포인트를 구축하며 이미지 컨벌루션 구조를 구축한 후 이미지 컨벌루션 모델을 추가하여 이미지 특징의 핵심을 개선한다. 마지막으로 두 사람의 얼굴의 이미지 특징 텐서를 계산하고 전체 연결 레이어를 사용하여 집계된 특징을 추출하고 판별하여 인원의 신원이 동일한지 여부를 결정한다. 최종적으로 다양한 실험과 테스트를 거쳐 이 글에서 설계한 네트워크의 얼굴 핵심 포인트에 대한 위치 정확도 AUC 지표는 300W 오픈 소스 데이터 세트에서 85.65%에 도달했다. 자체 구축 데이터 세트에서 88.92% 증가했다. 얼굴 인식 정확도 측면에서 이 글에서 제안한 IBUG 오픈 소스 데이터 세트에서 네트워크의 인식 정확도는 83.41% 증가했으며 자체 구축 데이터 세트의 인식 정확도는 96.74% 증가했다. 실험 결과는 이 글에서 설계된 네트워크가 얼굴을 모니터링하는 데 더 높은 탐지 및 인식 정확도를 가지고 있음을 보여준다.

• 디자인학연구
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• 제19권5호
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• pp.119-128
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• 2006

미디어의 발전과 함께 시각표현은 정지화면에서 동영상으로 그 영역이 확대되었다. 애니메이션 영화, TV CM, GUI 등과 같은 분야는 프레임이 누적된 가현운동 현상이 나타나면서 쇼트, 씬과 같은 단위 구조가 만들어지므로 정지화면에 비해 움직임이 필연적인 조형요소가 된다. 따라서 형태, 색채, 공간, 크기, 움직임과 같은 조형요소 중에서 움직임은 특히 중요한 요소로 부각된다고 볼 수 있다. 소쉬르(Saussure)가 설명한 기표와 기의의 관계처럼 이미지의 표현과 형식은 그 내용과 서로 제약을 주는 반면 상호 보완에 의해 하나의 기호로서 수용된다. 이는 움직임 역시 그 형식적 특성이 메시지가 담고 있는 내용에 어떠한 관여를 할 것이라는 추론을 가능하게 한다. 이를 분석하기 전 먼저 게슈탈트이론 중 '그룹핑의 원리'를 이론적 근거로 하여 동영상 시지각 실험을 실시하여 움직임과 타 조형요소의 관계를 조사하였다. 그 결과 약 70-80%의 피실험자가 '움직임'을 지각 상 중요한 그룹핑 단서로 생각하는 것으로 나타났다. 이러한 형식적 특성을 토대로 동영상의 구조를 분석했을 때 움직임은 커뮤니케이션 과정에서 메시지의 의미의 맥락을 유지하는데 영향을 준다. 사람이나 사물, 배경의 형태와 색 등이 변하더라도 움직임이 유사한 지향점을 가지면 그 대상의 정체성은 유지될 수 있다. 둘째, 움직임에 의해 형상(figure)으로서 대상이 부각되므로 내용의 명료성을 높여준다. 셋째 추후 정보처리에 있어서 유사한 움직임의 진행을 예측할 수 있는 지식표상으로 작용하게 된다. 넷째, 교차편집과 같이 둘 이상의 씬이 빠르게 전환되고 복잡한 편집구조를 가지더라도 움직임이 내용에 일관성을 부여하는 성격을 갖는다. 움직임은 기본적인 시지각적 반응으로서 입력되는 시각정보를 그룹화시키는 하나의 단서가 된다. 또한 영상 메시지의 구조적인 틀을 형성하는데 관계하여 자칫 현란하고 남용될 수 있는 시각적 표현에 질서를 부여하고 의미 작용에 명료함을 높이는 효율성을 가진다. 동영상은 본질적으로 시간성을 내포하므로 다수의 단위 구조가 조합된 담화를 가지며, 미디어믹스 환경에 의해 공통적이면서도 차별화된 표현이 요구되고 있다. 따라서 본 연구는 게슈탈트 이론의 그룹핑 원리를 동영상 범주로 확대하여 적용해 봄으로써 움직임이 다른 조형요소보다 부각되는 속성이 됨과 의미구조 형성에 영향을 줌을 분석하였으며, 이는 미디어 특성에 따라 각 영상분야에서 구조적 조형미와 새로운 영상표현을 개발하는 관점이 될 수 있음을 제안한다.

• 디자인학연구
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• 제18권4호
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• pp.277-286
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• 2005

새로운 문화 시대의 대두와 동아시아의 문화적 역할 증대는 한국문화의 위상과 정체성 확립을 필요로 하게 되었다. 이에 본 연구는 조형의 기본인 의장, 특히 색채와 재료, 문양을 중심으로 실제 조사를 통해 유사한 한중일 삼국 문화 속에서 공통성과 차별성을 파악하고 이를 통해 한국 의장 군화의 정체성을 규명하는 것을 그 목적으로 한다. 연구는 문헌조사와 현지 답사조사를 함께 진행하였으며 조사의 대상이 된 한중일의 궁궐은 창덕궁, 자금성, 니조성이다. 본 연구의 결과 파라된 한국 의장 문화의 정체성은 다음과 같다. 한국의 의장 문화는 삼국 문화의 공통 기반을 이루는 자연 친화 사상, 조화론, 유교 문화를 기본으로 인본주의의 영향이 가장 강하게 나타난 것으로서 이는 중국에서의 중화사상, 일본의 집단주의적 특성과 차별화 되어 나타난다. 문화와 건축 위에 나타나는 한국의 의장은 자연 재료와 자연색 사용, 자연 모티브의 문양 등의 한중일 공통적 특성과 함께 재료에 있어 자연적 가공도가 높고 대체적으로 거친 질감을 살리고 있으며 색채 면에서도 따뜻하고 부드러운 색 변화, 유사배색으로 자연스러움을 추구하였다. 또한 한국의 문양은 부드럽고 도톰한 선을 사용하여 인간적인 소박성을 보이고 있었다. 이에 비해 중국의 의장은 재료의 가공도가 높고, 표면 질감이 매끈하며 색채는 매우 화려하고 사실적 표현의 장식을 주로 하는 특성을 지닌다. 일본은 재료의 가공도가 높으나 질감 면에서는 자연스러운 거친 질감이 많으며 색채는 차분하고 안정적이며 무채색, 중성색을 중심으로 유사배색을 즐긴다. 일본의 문양은 표현은 매우 추상화되고 양식화되어 있으나 세부 표현에서는 기교와 장식을 즐기는 이중적 성격을 띠고 있다.지 않은 요소임을 밝혀내었다. 본 연구는 예배공간의 종교적 숭고미와 관련되는 감성적 요구를 표현하는데 있어 디자이너의 주관적인 해석을 객관화, 정량화시켜 사용자의 감성적 만족을 높이고 공간의 유형과 목적을 만족시킬 수 있는 공간 디자인 접근에 도움이 되리라 본다.분석(conjoint analysis), (3) 상기의 2가지 접근방법의 상호보완적 및 동시적 결합 및 피드백의 주장(Pullman, Moore and Wardell, 2002)을 들 수 있다. 그러나 본 연구의 실증적 분석결과에는 품질경쟁력이 제품 디자인과 고객만족사이에 교량적 역할을 담당한다. 이 분석결과는 제품 디자인에 대한 품질경쟁력의 2가지 접근방법(QFD의 접근방법과 컨조인트 분석)의 조화를 이룰 수 있는 이론적 기초가 될 수 있다. 즉, 제품디자인의 결정요인 분석결과는 QFD의 접근방법에, 제품 디자인 파급효과 분석결과는 컨조인트 분석에 각각 보완적 기여를 할 수 있다. 이와 동시에, 실증적 분석결과는 Ettlie(1997)의 디자인 통합(DI) 이론에 대한 실증적 기반을 제공할 수 있다. 마지막으로, 성공적인 디자인 경영(DM)을 위해서는 최고 경영자의 지원뿐만 아니라 부처 간 의사소통의 장애요인을 제거하고 CFT(cross-functional team)를 운영함으로써 동시적 엔지니어링(CE) 및 제품 및 공정 디자인의 개발이 제품 개발의 속도를 가속화하고 디자인 품질을 높이며 시장 성공을 보증할 수 있도록 해야 한다.임과 채팅은 긍정적인 상호관련을 가진 것으로 나타난 반면 전자메일 서비스 이용은 성적 만족과 부정적인 상호관련을 가진 것으로 분석되었다. 이는 대학생들이 지루하게 느끼거나 외로움을 느낄 때 전자메일을

• 만화애니메이션 연구
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• 통권48호
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• pp.359-383
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• 2017

3000년 전 이집트에서 인류 최초의 포스터가 등장한 이후 인쇄술의 발명과 문명의 발전으로 포스터 제작기술이 가속화 되었다. 이에 발맞추어 포스터의 표현 또한 단순 문자 배열에서 예술적 감성을 함께 표현하려는 시도로 발전되었으며, 이제는 전문 디자이너의 영역으로 자리 잡은 하나의 예술 형식이 되었다. 하지만 포스터의 표현 방식에 대한 기술적 변화는 이차원적 발전에 머무르고 있으며, 현대의 멀티미디어를 기반으로 하는 ICT 환경변화와는 무관한 듯 인쇄에만 의존하고 있는 상황이다. 특히, 수많은 종류의 포스터 가운데 유일하게 영상물을 대상으로 하는 영화 포스터의 양식이 아직도 종이인쇄에 그치고 있고, 지금까지 여러 시도는 있어 왔지만 영화계는 여전히 ICT 접목에 대해서는 전혀 고려치 않는 듯 같다. 이 연구는 영화포스터의 대상이 영상물을 다루고 있다는 특징으로부터 시작하여 영화의 동적 이미지를 정적 포스터에 접목시키기 위해 증강현실을 도입하는 시도를 하였다. 국내 한 대학의 영상디자인전공 졸업작품에서 학생들의 영상작품홍보를 위한 각 작품들의 포스터를 일반 상업영화 포스터 형식으로 디자인하여 인쇄하였으며, 이 중 증강현실 적용에 적합하다고 판단되는 6작품을 선별하여 증강현실을 도입하고 전시하였다. 모바일 디바이스를 통해 포스터와 정합되어 나타나는 콘텐츠는 영상물의 한 장면이 포스터 위에서 재현되지만, 원래 포스터가 표현하고 있는 텍스트 정보 등은 그대로 유지되도록 하여, 마치 영화 "해리포터"에서 등장한 현상수배 포스터와 같이 움직이는 포스터를 구현할 수 있었다. 본 증강현실 포스터 제작을 위해 두 가지 다른 형식으로 제작된 기존 상업영화의 포스터에 증강현실을 도입해 봄으로써 AR 콘텐츠의 특징을 배가시킬 수 있는 방법을 찾아 본 작품에 적용할 수 있었다. 이를 통해 AR 표현이 적합한 포스터디자인을 알 수 있었으며, 증강현실 콘텐츠 제작의 정합과정에서 증강현실의 안정적 구동을 위한 기술적 표현에 대해 정리할 수 있었다.

• 정보처리학회논문지A
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• 제11A권5호
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• pp.383-390
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• 2004

본 논문은 사용자로 하여금 얼굴표정들의 공간으로부터 일련의 표정을 실시간 적으로 선택하게 함으로써 3차원 아바타의 얼굴 표정을 제어하는 기법을 제안하고, 해당 시스템을 구축한다. 본 시스템에서는 얼굴 모션 캡쳐 데이터로 구성된 2400여개의 표정 프레임을 이용하여 표정공간을 구성하였다. 본 기법에서는 한 표정을 표시하는 상태표현으로 얼굴특징 점들 간의 상호거리를 표시하는 거리행렬을 사용한다. 이 거리행렬의 집합을 표정공간으로 한다. 그러나 이 표정공간은 한 표정에서 다른 표정까지 이동할 때 두 표정간의 직선경로를 통해 이동할 수 있는 그런 공간이 아니다. 본 기법에서는 이 경로를 표정 데이터로부터 근사적으로 유추한다. 우선, 각 표정상태를 표현하는 거리행렬간의 거리가 일정 값 이하인 경우 두 표정을 인접해 있다고 간주한다. 임의의 두 표정 상태가 일련의 인접표정들의 집합으로 연결되어 있으면 두 표정간에 경로가 존재한다고 간주한다. 한 표정에서 다른 표정으로 변화할 때 두 표정간의 최단경로를 통해 이동한다고 가정한다. 두 표정간의 최단거리를 구하기 위해 다이내믹 프로그래밍 기법을 이용한다. 이 거리행렬의 집합인 표정공간은 다차원 공간이다. 3차원 아바타의 얼굴 표정은 사용자가 표정공간을 항해하면서 원하는 표정을 실시간 적으로 선택함으로써 제어한다. 이를 도와주기 위해 표정공간을 다차원 스케일링 기법을 이용하여 2차원 공간으로 가시화 했다. 본 시스템이 어떤 효과가 있는지를 알기 위해 사용자들로 하여금 본 시스템을 사용하여 3차원 아바타의 얼굴 표정을 제어하게 해본 결과, 3차원 아바타의 실시간 얼굴 표정 제어가 필요한 각 분야에서 매우 유용하게 사용될 것으로 판단되었다.24시간 경과시킨 후 치아의 장축에 따라 절단하여 침투된 색소의 정도를 광학현미경상에서 40배로 관찰하였다. 각각의 실험결과는 ANOVA/Tukey's test 및 Kruskal-Wallis non-parametric independent analysis와 Mann-Whitney U test에 의하여 통계 분석하여 다음과 같은 결론을 얻었다. 1. 대조군에 있어서 혼합형 복합레진의 미세인장 결합강도는 미세혼합형에 비하여 높았으며, 실험군 사이에는 유의차를 보이지 않았다. 2.모든 복합레진의 미세인장 결합강도는 와동의 C-factor증가에 따라 감소하는 경향을 나타내었고, 혼합형 복합레진의 실험군은 대조군에 비하여 낮게 나타났으며, 미세혼합형 복합레진에서는 유의차를 보이지 않았다. 3. 절단측 및 치은측 변연부의 미세누출정도는 혼합형 복합레진이 미세혼합형에 비하여 대체로 높게 나타났다. 4. 모든 실험군에서 미세누출은 C-factor증가에 따라 증가하였고 절단측에 비하여 치은측 변연이 높게 나타났으나 통계학적 유의차는 보이지 않았다. C-factor의 변화에 대하여 필러함량과 탄성계수가 높은 혼합형 복합레진이 미세혼합형에 비하여 더 민감한 결과를 보인다. 이는 복합레진 수복시 재료의 선택과 중합수축의 적절한 조절이 중요한 요소임을 시사한다.s에서는 1주, 2주에서 강한 염증반응을 보였으나 12주에서는 염증반응이 감소하였다. 4) 새로 개발된 봉함제 Adseal-1,2는 1주, 2주에서는 가장 약한 염증반응을 보이나 4주, 12주 후에는 AH Plus와 비슷한 수준의 염증 반응을 보였다. 5) Pulp Canal Sealer를 제외한 모든 군에서 인정할 만한 생체친화성을 보였다. 6)

• 한국전통조경학회지
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• 제29권4호
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• pp.27-39
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• 2011

본 연구는 경남 진주시 용호정원에 조성된 무산십이봉이 전통적 축산(Mount)의 원형이자, 지형의 단조로움을 극복하고 변화와 흥미를 유발할 수 있는 설계요소라는 전제 아래 시작되었다. 또한 연구 결과가 축산되는 유사공간의 재현 및 현대적 변용에 필요한 자료 및 시사점을 제공할 수 있을 것이란 기대 또한 크다. 무산십이봉 축산을 통해 조영자가 추구하고자 했던 12봉우리의 상징성과 공간구성원리 그리고 시각구성상의 기능 및 효과를 조망경관적 측면에서 분석 또는 해석한 본 연구의 결과는 다음과 같다. 용호정원의 핵심인 용호지는 비보 풍수적 차원에서 만들어진 인공혈구의 전형적 사례로 풍수형국의 완결을 위한 비보(裨補)의 장치이자 용과 관련한 지명의 연계를 통해 온전함을 강화시키고자 했던 산물이다. 축산의 크기는 높이 2~3.5m, 지름 약 6~12m정도의 오성상 금성산형을 하고 있으며, 봉우리의 높이는 1.9~3.2m, 평균값은 2.5m로 밝혀졌다. 봉우리의 면적은 $35{\sim}138m^2$의 범위에 있고, 면적 평균값은 $73.4m^2$로 나타났으며 이에 비례한 체적은 $30.7{\sim}115.0m^3$, 그 평균값은 $62.5m^3$으로 추산되었다. 용호정과 소선 그리고 본채 터 및 용산재의 일치된 축에서도 알 수 있듯이 선과 속의 의미 부여를 통해 용호지를 피안의 세계로 상정하였으며, 조영자는 무산십이봉의 형상을 구현시키기 위한 의도로 호두 자리에서 대응되는 지점과 교차되도록 용의 골격을 형상화한 12개의 봉우리를 축산하고, 그 중심에 '여의주를 문 용이 욱일승천(旭日昇天)하는 형상'의 무산십이봉과 용호정을 배치한 것으로 보인다. 무산십이봉 주변 중경권역은 남북으로 금성산형의 산봉으로 둘러싸여, 용호지를 중심으로 동질감을 유지한채 다층의 층위구조를 보이는 바, 이는 유사 형태조화에 기인하며 무산십이봉의 조성 시 기획된 축산의도라 사료된다. 무산십이봉 축산에는 은폐와 노출을 통한 점진적인 경관연출과 전망-은신처이론 그리고 틀에넣기 기법 등의 공간 질서가 깊숙이 내재되어 있는데, 이는 무산십이봉 각 봉우리의 노출과 둘러싸임 정도의 다양함, 전망과 시선차단 조합의 다채로움을 통해 경관의 심도와 기대감을 높이고자한 의도가 반영된 것으로 보인다. 무산십이봉에 의해 '닫힌경관'은 흥미롭고 생기 있으며 매력적인 경관인식을 배태(胚胎)하는데, 특히 축산은 용호지와 용호정 주변에 관한 경관의 심도와 흥미를 불러일으키는 지형설계적 차원에서 매우 유용하게 작용하고 있다. 더불어 용호정에서 조망하였을 때 섬을 통해 또 다른 섬이 보이도록 하는 중층적 노출효과를 의도해 특수한 위치를 배려한 경관짜임의 결과인 12개 봉우리의 묶음이 이루어졌음을 확인하였다.

• 대중서사연구
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• 제27권3호
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• pp.13-51
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• 2021

본 논문의 목적은 만화 연구에서 소외되었던 1970년대 순정만화를 조명하는 것이다. 본 논문에서는 1970년대의 잡지인 『여학생』의 기사와 연재만화를 분석하고 당시의 이상적인 소녀상을 고찰한다. 순정만화는 1960년대와 1970년대의 차이가 상당히 크다. 단행본 순정만화 분석만으로는 이러한 간극에 대해 설명되지 않는다. 만화 검열이 만화 전반의 발전을 저해하는 요소로 작용했지만 다른 장르의 만화와 비교했을 때 1970년대 순정만화의 정체는 지나치다. 순정만화와 함께 소녀를 대상으로 하는 대표적인 대중매체였던 잡지 연구를 통해 순정만화 변화의 원인에 대한 답을 얻을 수 있을 것이다. 잡지의 기사는 그 잡지의 편집방침과 특징을 보여주기도 하지만 그 시대의 가치관과 이념을 반영한다. 잡지에 실린 만화 역시 마찬가지이다. 특히 잡지 만화는 검열에서 비교적 자유로웠다. 본 논문에서는 1970년대 소녀잡지의 기사와 만화가 당시의 소녀상을 어떻게 형성했는지 『여학생』의 특집 기사와 만화를 통해 분석했다. 『여학생』에 연재된 만화 중에서 엄희자의 <푸른 지대>와 방영진의 <미니 행진곡>을 살펴보았다. <푸른 지대>와 <미니 행진곡> 모두 『여학생』의 기사에서 강조한 이상적인 소녀상을 보여준다. <푸른 지대>는 가정 안의 성실하고 순종적인 딸의 모습을, <미니 행진곡>은 명랑하고 밝은 소녀의 모습을 그린다. 연구를 통해 1970년대 잡지는 사회에 순응하면서 화목한 가정을 돕는 소녀를 이상적인 소녀로 평가했다는 것 그리고, 잡지에서 끊임없이 주장했던 이상적인 소녀상은 순정만화의 검열과 창작의 기준이 되어 많은 작품의 내용과 표현에 큰 영향을 주었다는 것을 알 수 있었다. 1970년대는 만화 검열과 합동 출판사의 독과점 전횡으로 연구사적 의미에서 그 중요성이 희석된 시기이다. 검열의 틀에서 표현의 한계가 명확했고 그 결과 양질의 작품도 많지 않아 1970년대 한국만화 연구는 많은 부분이 공백으로 남아 있다. 본 연구는 1970년대 만화 연구의 공백을 채우는 데에 의미가 있다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.