• 한국산학기술학회논문지
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• 제13권8호
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• pp.3405-3416
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• 2012

음악줄넘기가 남중생의 건강체력, 혈중지질 및 성장관련인자에 미치는 영향을 구명하기 위하여 G시에 거주하는 남자 중학생 20명을 대상으로 실시하였다. 운동프로그램은 12주간, 주 4회, 1일 45분, 1주기(1-6주)는 RPE 11-12(저강도), 2주기(6-12주)는 RPE 13-15로 실시하여 비교 분석한 결과 다음과 같은 결론을 얻었다. 첫째, 건강체력에서 각 집단 내의 음악줄넘기 실시 전 후의 변화에서 운동군은 제지방량, 근력, 근지구력, 심폐지구력, 유연성에서 유의하게 증가하였으나, 체지방률은 유의하게 감소하였다. 대조군은 근력, 근지구력, 심폐지구력에서 유의하게 증가하였으며, 각 집단 간의 변화량에 대한 차이검정에서는 제지방량, 체지방률, 근력, 유연성에서 유의한 차이가 나타났다. 둘째, 혈중지질에서 각 집단 내의 전 후의 변화에서 운동군은 HDL-C에서 유의하게 증가하였으나, 대조군은 TG에서 유의하게 감소하였으며, HDL-C는 유의하게 증가하였고, 각 집단 간의 변화량에 대한 차이검정에서는 모두 유의한 차이가 나타나지 않았다. 셋째, 성장관련인자에서 각 집단 내의 전 후의 변화에서 운동군은 성장호르몬, IGF-I에서 유의하게 증가하였다. 대조군은 IGF-I에서 유의하게 감소하였고, 각 집단 간의 변화량에 대한 차이검정에서는 IGF-I에서 유의한 차이가 나타났다. 이상의 연구결과에서 남자 중학생에게 음악줄넘기가 제지방량, 근력, 유연성, 성장호르몬, IGF-I에 긍정적인 효과가 있는 것으로 나타났다.

• Experimental and Molecular Medicine
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• 제50권12호
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• pp.2.1-2.12
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• 2018

Glucagon-like peptide-1 (GLP-1) has a broad spectrum of biological activity by regulating metabolic processes via both the direct activation of the class B family of G protein-coupled receptors and indirect nonreceptor-mediated pathways. GLP-1 receptor (GLP-1R) agonists have significant therapeutic effects on non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) in animal models. However, clinical studies indicated that GLP-1 treatment had little effect on hepatic steatosis in some NAFLD patients, suggesting that GLP-1 resistance may occur in these patients. It is well-known that the gut metabolite sodium butyrate (NaB) could promote GLP-1 secretion from intestinal L cells. However, it is unclear whether NaB improves hepatic GLP-1 responsiveness in NAFLD. In the current study, we showed that the serum GLP-1 levels of NAFLD patients were similar to those of normal controls, but hepatic GLP-1R expression was significantly downregulated in NAFLD patients. Similarly, in the NAFLD mouse model, mice fed with a high-fat diet showed reduced hepatic GLP-1R expression, which was reversed by NaB treatment and accompanied by markedly alleviated liver steatosis. In addition, NaB treatment also upregulated the hepatic p-AMPK/p-ACC and insulin receptor/insulin receptor substrate-1 expression levels. Furthermore, NaB-enhanced GLP-1R expression in HepG2 cells by inhibiting histone deacetylase-2 independent of GPR43/GPR109a. These results indicate that NaB is able to prevent the progression of NAFL to NASH via promoting hepatic GLP-1R expression. NaB is a GLP-1 sensitizer and represents a potential therapeutic adjuvant to prevent NAFL progression to NASH.

• 시큐리티연구
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• 제57호
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• pp.85-110
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• 2018

경호원은 경호 대상자의 신변을 외부의 우발상황과 위협에 대비하고 대처하기 위해 기본적인 체력훈련과 경호무도를 지속적으로 수련하고 있으며, 현재 경호전공 대학생들은 보편적으로 상대를 잡고 메치고 제압하는 기술을 유용하게 사용할 수 있는 경호무도 중 하나인 유도 수업을 의무적으로 실시하고 있다. 따라서 본 연구는 10주간의 유도수련 운동프로그램을 통해 체계적인 훈련이 경호무도전공 남자대학생들의 신체구성, 행동체력, 성장 호르몬 및 IGF-1에 어떠한 영향을 미치는지 파악하여 경호무도로써 유도의 가치를 제고할 수 있는 객관적 자료를 제공하는데 의의를 두었으며, 그 결과 다음과 같은 결론을 얻었다. 10주간의 유도수련 후 근육량은 유의하게 증가하는 것으로 나타났으며, 체지방률과 BMI 등은 유의하게 감소하는 것으로 나타났다. 행동체력의 근력과 순발력은 유의하게 증가하는 것으로 나타났으며, 성장호르몬은 유의하게 증가하는 것으로 나타났다. 이상의 결과를 종합해 볼 때, 유도수련 대학생들은 전반적으로 신체구성은 긍정적으로 개선되었고 행동체력의 근력과 순발력은 향상되었으며, 성장호르몬을 증가 시켰다. 따라서 유도수련을 통한 근력과 성장호르몬의 증가는 신체의 근육의 발달로 인해 지방 분해를 촉진시키고 척추의 골밀도를 높여서 골절의 위험을 줄여 수련자들의 부상을 방지해 줄 것이다. 또한 비만 예방, 심혈관질환, 대사성질환을 방지하여 경호업무기능을 높여 주고 경호원으로서의 수명을 연장하는 계기가 될 것으로 사료된다.

• 방사선산업학회지
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• 제7권1호
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• pp.37-43
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• 2013

We examined the forage quality to provide the basic information for the utilization of blackberry by-products (leaf and stem) among thirty-five mutant lines derived from gamma-ray. The leaves had higher crude protein (CP) contents than stems. In addition, the leaves showed broad ranges of variation in crude fat, crude fiber and crude ash. The overall forage quality of the stems were similar to those of the original variety. The mean of neutral detergent fiber (NDF) content of leaves and stems in mutant lines were 25.88% and 58.98%, respectively. Also, the mean of acid detergent fiber (ADF) content of leaves and stems in mutant lines were 15.43% and 49.27%, respectively. Forage quality grades of all blackberry leaf were special quality class. However, the blackberry stem ranked $1^{st}$ to $5^{th}$ in quality class. The stem diameter was negatively ($P{\leq}0.05$) correlated with the moisture and crude protein. Also, the fruit length was highly negatively ($P{\leq}0.01$) correlated with the RFV (relative feed value) in blackberry leaf. The one hundred fruit weight was highly negatively ($P{\leq}0.01$) correlated with the crude ash. Based on these results, the by-products of blackberry could provide high quality forage for feeding of live stock.

• 대한영양사협회학술지
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• 제21권3호
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• pp.203-214
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• 2015

A survey was conducted to determine the perception of youku meat among college students majoring in food and/or nutrition. The survey participants were located nationwide, and the responses from the 2,454 students were analyzed. More male and higher grade students answered that they had heard about youku while only 20.0% had learned about Youku from class. Approximately 37.8% of the subjects recognized youku as 'dairy cattle which are too old to produce milk', 54.0% as 'all cattle grown for the purpose of meat', and 23.1% as 'all cattle except for Hanwoo'. Only 37.4% recognized youku correctly. Compared with the same quality grade, 25.3% recognized youku meat as being cheaper than imported beef, and only 25.6% of them recognized that youku meat has less fat than imported beef. As much as 83.3% of subjects did not know whether or not they were served youku meat, and 23.7% of subjects wanted increased availability of youku meat. As much as 22.9% of subjects opposed the increased use of youku meat, and the reasons were "it does not taste good" (18.1%), "it is not Hanwoo" (15.1%), "it is not sanitary" (13.1%), and "it is imported" (6.0%). The findings provide basic information on barriers regarding youku meat promotion among subjects who will be dieticians in food service or managers in purchase departments of catering companies in the future.

• Preventive Nutrition and Food Science
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• 제8권3호
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• pp.253-259
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• 2003

Conjugated linoleic acid (CLA) is a class of positional, geometric conjugated dienoic isomers of linoleic acid (LA). CLA activates the immune system, protects against tumorigenesis, and reduces the incidence of atherosclerosis. Trans-10, cis-12 CLA has specific effects on lipid metabolism, it has been shown to reduce body fat gain and regulates some adipocyte secreted proteins in vivo and in vitro. Here we report that a CLA mixture affects cytokine secretion from rat primary adipocytes. Rat primary adipocytes were treated with 1 mM, 100 $\mu$M, 1 $\mu$M or 100 nM CLA mixture doses; and leptin, tumor necrosis factor alpha (TNF a ), interleukin-6 (IL-6) and glycerol levels in the medium were measured. Leptin secretion was lower, TNF $\alpha$ secretion higher and IL-6 secretion did not change in response to the CLA mixture. Leptin and TNF $\alpha$ secretions did not change with CLA mixture treatment in a dose-dependent manner. In addition, the CLA mixture did not appear to enhance lipolysis in rat primary adipocytes. In conclusion, our study demonstrates that the decrease in leptin and increase in TNF $\alpha$ secretion in adipocytes treated with CLA mixture may be due to the apoptotic effect and to a reduction in peroxisome proliferator-activated receptor gamma (PPAR ${\gamma}$ ) ligands.

• Journal of Animal Science and Technology
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• 제56권8호
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• pp.31.1-31.9
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• 2014

The objective of this study was to describe the population structure and inbreeding, and to quantify their effects on weights at different ages of Mehraban sheep in Iran. The analysis was based on the pedigree information of 26990 animals and 10278 body weight records from birth to yearling age. Data and pedigree information were collected during 1994 to 2011 by the breeding station of Mehraban sheep. The population structure was analyzed using the CFC program. Inbreeding of all animals was calculated by INBUPGF90 program. All animals were grouped into three classes according to their inbreeding coefficients: the first class included non-inbred animals (F=0); and the second and third classes included inbred animals (0$F{\geq}0.05$, respectively). The average inbreeding in Mehraban sheep was 1.69%. Founder equivalent ($f_e$) values were estimated to be 4244, 3116 and 2965 during 1994-1999, 2000-2005 and 2006-2011, respectively. The effective population sizes ($N_e$) were 363, 5080 and 5740 during 1994-1999, 2000-2005 and 2006-2011, respectively. Generation interval was 2.15 years for this breed of sheep. Regression coefficients of birth weight, 3-month weight, 6-month weight and yearling weight on lamb inbreeding were estimated to be -6.340.69, -14.685.33, 48.009.43 and 98.6515.65, respectively. Both positive and negative inbreeding effects were found in the current study. The utilization of a program for designed mating system, in the present flock, could be a suitable approach to keep the level of inbreeding under control.

• 한국양식학회지
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• 제15권1호
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• pp.7-13
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• 2002

Since 1993, the White Spot Syndrome Virus (WSSV) disease occurred in China among cultured shrimps resulting in mass mortality. Epizootiological surveys undertaken during the outbreak period of 1993-1994 indicated that all stages of Penaeus chinensis, P. japonicus and P. monodon were infected. Consequent to the transport of contaminated shrimp seedlings and seawater, the disease spread all over the farms of China. The disease was more rapidly transmitted at temperatures above $25^{\circ}C$. Challenge experiments showed the causative agent was highly virulent. White spots appeared on the carapace of both span-taneous and experimentally infected shrimps. Moribund shrimps contained turbid hemolymph, hypertrophied Iymphoid organ and a necrotic mid-gut gland. Electron microscopy showed the presence of viral particles in the gills, stomach, lymphoid organ, and epidermal tissue of the infected shrimp. The visions were slightly ovoid with an envelope and averaged 350 $\times$ 150 nm; nucleocapsids measured 375 $\times$ 157 nm. With discontinuous sucrose gradient of 35, 50 and 60% (w/v), the virus was separated from hemolymph of the infected shrimp. The estimated molecular weight of genomic DNA was 237 Kb with EcoR I, 247 Kb with Hind III and 241kb with Pst I. A total of 9 hybridoma colones secreting monoclonal antibodies (MAbs) were produced from mouse myeloma and spleen cells immunized with WSSV. The immunofluorescence assay of gill tissue showed that the MAbs reacted with diseased but not with healthy shrimp. The MAbs belonged to IgGl, IgG2b subclass and IgM class, all with kappa light Immune-electron-microscopy with colloidal gold marker showed the presence of 5 MAbs epitopes on the envelope and one on the capsid of the virus. Baculoviral mid-gut gland necrosis showed the specificity of the MAbs produced. For diagnosis 5 different methods were selected. Using Kimura primers for PCR, or MAbs for immunoblot, ELISA or FAT method, in situ hybridization was carried out to show the gene. All these methods detected WSSV in the organ samples of the diseased shrimp but not in healthy one.

• 한국식품영양과학회지
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• 제11권2호
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• pp.13-20
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• 1982

(1) 남녀아(男女兒) 모두 전영양소(全營養素)에 있어서 섭취량(攝取量)이 권장량(勸?量) 보다 부족(不足)했으며 특(特)히 calcium과 vitamin $B_2$가 제일(第一)낮았다(2) 단백질총섭취양중(蛋白質總攝取量中) 동물성단백질(動物性蛋白質)의 비률(比率)은 전체적(全體的)으로 33.38%였다. (3) 열량섭취양(熱豊攝取量)의 구성비(構成比)는 당질(糖質) 지방(脂肪) 단백질(蛋白質)에 있어서 남아(男兒)는 79 : 11 : 10이었고 여아(女兒)는 77 : 12 : 10이었다. (4) 도시학의 주식(主食)은 남아(男兒)에 있어서 열량(熱量), total-protein, iron, vitamin $B_l$, vitamin $B_2$, niacin 등(等)이 도시락 전량(全量)에 비(比)해 83.92%, 65.93%, 37.81%, 31.72%, 56.00%, 36.84%, 53.13%였고, 여아(女兒)에 있어서는 81.19%, 51.91%, 27.73%, 36.65%, 39.96%, 36.84%, 51.00%를 나타냈다. (5) 체위발달(體位發達)에 있어서는 남여아(男女兒) 모두 Rohrer index가 표준(標準)에 미달(未達)했으며, Kaup index, Vervaeck index의 미달(未達)이 영양(營養)과 체위발달(體位發達)에 상호관계(相互關係)가 있음을 나타했다.

• 한국생활과학회지
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• 제17권1호
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• pp.159-170
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• 2008

This study was carried out for the prevalence of metabolic syndrome in obese middle school students. The subjects were 104 obese adolescents of 4 middle schools in Namwon city, Jeonbuk. Average age of the subjects was 12.2 years old, BMI of mild obesity group, moderate obesity group and severe obesity group were 24.6kg/m2, 27.5kg/m2, and 31.8 kg/m2, respectively. Prevalence of metabolic syndrome in obese students was 2.9%. And the person who has more than 2 out of 5 symptoms was 22.1%, and more than 1 was 39.4%. The prevalence of each symptoms were abdomen obesity(46.2%), hyper triglyceride(23.1%), high blood pressure(20.2%), high HDLcholesterol(2.9%), but the hyper glycemia had not been found. Nutrient intakes of 3 groups were not significantly different, energy was 1817.9kcal, carbohydrate was 265.7g, protein was 72.2g, and fat was 51.9g. Nutrient adequacy ratio(NAR) of protein, phosphorus, iron, vitamin A, vitamin B1, vitamin B1, niacin, vitamin C was proper, except calcium. Seventy point two percent of the obese students knew 'obesity is a disease', and 49.0% of the subjects didn't know the complication of the obesity. Only 27.9% of the obese adolescents took nutrition education class, but 51.9% of them thought nutrition education was necessary. We suggest that the nation enforce the policy for early detection and treatment of obesity for adolescents. Obese students and their parents should take nutrition education.