• Title/Summary/Keyword: Fast Fourier Transform

Search Result 847, Processing Time 0.024 seconds

Receptor binding motif surrounding sites in the Spike 1 protein of infectious bronchitis virus have high susceptibility to mutation related to selective pressure

  • Seung-Min Hong;Seung-Ji Kim;Se-Hee An;Jiye Kim;Eun-Jin Ha;Howon Kim;Hyuk-Joon Kwon;Kang-Seuk Choi
    • Journal of Veterinary Science
    • /
    • v.24 no.4
    • /
    • pp.51.1-51.17
    • /
    • 2023
  • Background: To date, various genotypes of infectious bronchitis virus (IBV) have co-circulated and in Korea, GI-15 and GI-19 lineages were prevailing. The spike protein, particularly S1 subunit, is responsible for receptor binding, contains hypervariable regions and is also responsible for the emerging of novel variants. Objective: This study aims to investigate the putative major amino acid substitutions for the variants in GI-19. Methods: The S1 sequence data of IBV isolated from 1986 to 2021 in Korea (n = 188) were analyzed. Sequence alignments were carried out using Multiple alignment using Fast Fourier Transform of Geneious prime. The phylogenetic tree was generated using MEGA-11 (ver. 11.0.10) and Bayesian analysis was performed by BEAST v1.10.4. Selective pressure was analyzed via online server Datamonkey. Highlights and visualization of putative critical amino acid were conducted by using PyMol software (version 2.3). Results: Most (93.5%) belonged to the GI-19 lineage in Korea, and the GI-19 lineage was further divided into seven subgroups: KM91-like (Clade A and B), K40/09-like, QX-like (I-IV). Positive selection was identified at nine and six residues in S1 for KM91-like and QX-like IBVs, respectively. In addition, several positive selection sites of S1-NTD were indicated to have mutations at common locations even when new clades were generated. They were all located on the lateral surface of the quaternary structure of the S1 subunits in close proximity to the receptor-binding motif (RBM), putative RBM motif and neutralizing antigenic sites in S1. Conclusions: Our results suggest RBM surrounding sites in the S1 subunit of IBV are highly susceptible to mutation by selective pressure during evolution.

Investigation of thermal hydraulic behavior of the High Temperature Test Facility's lower plenum via large eddy simulation

  • Hyeongi Moon ;Sujong Yoon;Mauricio Tano-Retamale ;Aaron Epiney ;Minseop Song;Jae-Ho Jeong
    • Nuclear Engineering and Technology
    • /
    • v.55 no.10
    • /
    • pp.3874-3897
    • /
    • 2023
  • A high-fidelity computational fluid dynamics (CFD) analysis was performed using the Large Eddy Simulation (LES) model for the lower plenum of the High-Temperature Test Facility (HTTF), a ¼ scale test facility of the modular high temperature gas-cooled reactor (MHTGR) managed by Oregon State University. In most next-generation nuclear reactors, thermal stress due to thermal striping is one of the risks to be curiously considered. This is also true for HTGRs, especially since the exhaust helium gas temperature is high. In order to evaluate these risks and performance, organizations in the United States led by the OECD NEA are conducting a thermal hydraulic code benchmark for HTGR, and the test facility used for this benchmark is HTTF. HTTF can perform experiments in both normal and accident situations and provide high-quality experimental data. However, it is difficult to provide sufficient data for benchmarking through experiments, and there is a problem with the reliability of CFD analysis results based on Reynolds-averaged Navier-Stokes to analyze thermal hydraulic behavior without verification. To solve this problem, high-fidelity 3-D CFD analysis was performed using the LES model for HTTF. It was also verified that the LES model can properly simulate this jet mixing phenomenon via a unit cell test that provides experimental information. As a result of CFD analysis, the lower the dependency of the sub-grid scale model, the closer to the actual analysis result. In the case of unit cell test CFD analysis and HTTF CFD analysis, the volume-averaged sub-grid scale model dependency was calculated to be 13.0% and 9.16%, respectively. As a result of HTTF analysis, quantitative data of the fluid inside the HTTF lower plenum was provided in this paper. As a result of qualitative analysis, the temperature was highest at the center of the lower plenum, while the temperature fluctuation was highest near the edge of the lower plenum wall. The power spectral density of temperature was analyzed via fast Fourier transform (FFT) for specific points on the center and side of the lower plenum. FFT results did not reveal specific frequency-dominant temperature fluctuations in the center part. It was confirmed that the temperature power spectral density (PSD) at the top increased from the center to the wake. The vortex was visualized using the well-known scalar Q-criterion, and as a result, the closer to the outlet duct, the greater the influence of the mainstream, so that the inflow jet vortex was dissipated and mixed at the top of the lower plenum. Additionally, FFT analysis was performed on the support structure near the corner of the lower plenum with large temperature fluctuations, and as a result, it was confirmed that the temperature fluctuation of the flow did not have a significant effect near the corner wall. In addition, the vortices generated from the lower plenum to the outlet duct were identified in this paper. It is considered that the quantitative and qualitative results presented in this paper will serve as reference data for the benchmark.

Acoustic Emission (AE) Technology-based Leak Detection System Using Macro-fiber Composite (MFC) Sensor (Macro fiber composite (MFC) 센서를 이용한 음향방출 기술 기반 배관 누수 감지 시스템)

  • Jaehyun Park;Si-Maek Lee;Beom-Joo Lee;Seon Ju Kim;Hyeong-Min Yoo
    • Composites Research
    • /
    • v.36 no.6
    • /
    • pp.429-434
    • /
    • 2023
  • In this study, aimed at improving the existing acoustic emission sensor for real time monitoring, a macro-fiber composite (MFC) transducer was employed as the acoustic emission sensor in the gas leak detection system. Prior to implementation, structural analysis was conducted to optimize the MFC's design. Consequently, the flexibility of the MFC facilitated excellent adherence to curved pipes, enabling the reception of acoustic emission (AE) signals without complications. Analysis of AE signals revealed substantial variations in parameter values for both high-pressure and low-pressure leaks. Notably, in the parameters of the Fast Fourier Transform (FFT) graph, the change amounted to 120% to 626% for high-pressure leaks compared to the case without leaks, and approximately 9% to 22% for low-pressure leaks. Furthermore, depending on the distance from the leak site, the magnitude of change in parameters tended to decrease as the distance increased. As the results, in the future, not only will it be possible to detect a leak by detecting the amount of parameter change in the future, but it will also be possible to identify the location of the leak from the amount of change.

A study of Development of Transmission Systems for Terrestrial Single Channel Fixed 4K UHD & Mobile HD Convergence Broadcasting by Employing FEF (Future Extension Frame) Multiplexing Technique (FEF (Future Extension Frame) 다중화 기법을 이용한 지상파 단일 채널 고정 4K UHD & 이동 HD 융합방송 전송시스템 개발에 관한 연구)

  • Oh, JongGyu;Won, YongJu;Lee, JinSeop;Kim, JoonTae
    • Journal of Broadcast Engineering
    • /
    • v.20 no.2
    • /
    • pp.310-339
    • /
    • 2015
  • In this paper, the possibility of a terrestrial fixed 4K UHD (Ultra High Definition) and mobile HD (High Definition) convergence broadcasting service through a single channel employing the FEF (Future Extension Frame) multiplexing technique in DVB (Digital Video Broadcasting)-T2 (Second Generation Terrestrial) systems is examined. The performance of such a service is also investigated. FEF multiplexing technology can be used to adjust the FFT (fast Fourier transform) and CP (cyclic prefix) size for each layer, whereas M-PLP (Multiple-Physical Layer Pipe) multiplexing technology in DVB-T2 systems cannot. The convergence broadcasting service scenario, which can provide fixed 4K UHD and mobile HD broadcasting through a single terrestrial channel, is described, and transmission requirements of the SHVC (Scalable High Efficiency Video Coding) technique are predicted. A convergence broadcasting transmission system structure is described by employing FEF and transmission technologies in DVB-T2 systems. Optimized transmission parameters are drawn to transmit 4K UHD and HD convergence broadcasting by employing a convergence broadcasting transmission structure, and the reception performance of the optimized transmission parameters under AWGN (additive white Gaussian noise), static Brazil-D, and time-varying TU (Typical Urban)-6 channels is examined using computer simulations to find the TOV (threshold of visibility). From the results, for the 6 and 8 MHz bandwidths, reliable reception of both fixed 4K UHD and mobile HD layer data can be achieved under a static fixed and very fast fading multipath channel.

Changes of the Prefrontal EEG(Electroencephalogram) Activities according to the Repetition of Audio-Visual Learning (시청각 학습의 반복 수행에 따른 전두부의 뇌파 활성도 변화)

  • Kim, Yong-Jin;Chang, Nam-Kee
    • Journal of The Korean Association For Science Education
    • /
    • v.21 no.3
    • /
    • pp.516-528
    • /
    • 2001
  • In the educational study, the measure of EEG(brain waves) can be useful method to study the functioning state of brain during learning behaviour. This study investigated the changes of neuronal response according to four times repetition of audio-visual learning. EEG data at the prefrontal$(Fp_{1},Fp_{2})$ were obtained from twenty subjects at the 8th grade, and analysed quantitatively using FFT(fast Fourier transform) program. The results were as follows: 1) In the first audio-visual learning, the activities of $\beta_{2}(20-30Hz)$ and $\beta_{1}(14-19Hz)$ waves increased highly, but the activities of $\theta(4-7Hz)$ and $\alpha$ (8-13Hz) waves decreased compared with the base lines. 2). According to the repetitive audio-visual learning, the activities of $\beta_{2}$ and $\beta_{1}$ waves decreased gradually after the 1st repetitive learning. And, the activity of $\beta_{2}$ wave had the higher change than that of $\beta_{1}$ wave. 3). The activity of $\alpha$ wave decreased smoothly according to the repetitive audio-visual learning, and the activity of $\theta$ wave decreased radically after twice repetitive learning. 4). $\beta$ and $\theta$ waves together showed high activities in the 2nd audio-visual learning(once repetition), and the learning achievement increased highly after the 2nd learning. 5). The right prefrontal$(Fp_{2})$ showed higher activation than the left$(Fp_{1})$ in the first audio-visual learning. However, there were not significant differences between the right and the left prefrontal EEG activities in the repetitive audio-visual learning. Based on these findings, we can conclude that the habituation of neuronal response shows up in the repetitive audio-visual learning and brain hemisphericity can be changed by learning experiences. In addition, it is suggested once repetition of audio-visual learning be effective on the improvement of the learning achievement and on the activation of the brain function.

  • PDF

A Polarization-based Frequency Scanning Interferometer and the Measurement Processing Acceleration based on Parallel Programing (편광 기반 주파수 스캐닝 간섭 시스템 및 병렬 프로그래밍 기반 측정 고속화)

  • Lee, Seung Hyun;Kim, Min Young
    • Journal of the Institute of Electronics and Information Engineers
    • /
    • v.50 no.8
    • /
    • pp.253-263
    • /
    • 2013
  • Frequency Scanning Interferometry(FSI) system, one of the most promising optical surface measurement techniques, generally results in superior optical performance comparing with other 3-dimensional measuring methods as its hardware structure is fixed in operation and only the light frequency is scanned in a specific spectral band without vertical scanning of the target surface or the objective lens. FSI system collects a set of images of interference fringe by changing the frequency of light source. After that, it transforms intensity data of acquired image into frequency information, and calculates the height profile of target objects with the help of frequency analysis based on Fast Fourier Transform(FFT). However, it still suffers from optical noise on target surfaces and relatively long processing time due to the number of images acquired in frequency scanning phase. 1) a Polarization-based Frequency Scanning Interferometry(PFSI) is proposed for optical noise robustness. It consists of tunable laser for light source, ${\lambda}/4$ plate in front of reference mirror, ${\lambda}/4$ plate in front of target object, polarizing beam splitter, polarizer in front of image sensor, polarizer in front of the fiber coupled light source, ${\lambda}/2$ plate between PBS and polarizer of the light source. Using the proposed system, we can solve the problem of fringe image with low contrast by using polarization technique. Also, we can control light distribution of object beam and reference beam. 2) the signal processing acceleration method is proposed for PFSI, based on parallel processing architecture, which consists of parallel processing hardware and software such as Graphic Processing Unit(GPU) and Compute Unified Device Architecture(CUDA). As a result, the processing time reaches into tact time level of real-time processing. Finally, the proposed system is evaluated in terms of accuracy and processing speed through a series of experiment and the obtained results show the effectiveness of the proposed system and method.

Characteristics of EMG Median Frequency and Torque During Isometric Back Extension Exercises (등척성 요추 신전운동 시 중앙주파수와 토크의 특성)

  • Kang, S. J.;Park, S. J.;Jang, K.;Park, K. H.;Kwon, O. Y.;Kim, Y. H.
    • Journal of Biomedical Engineering Research
    • /
    • v.23 no.1
    • /
    • pp.9-16
    • /
    • 2002
  • Localized muscle fatigue can be identified by a downward shift of the EMG frequency typically represented by a fall in the median frequency The Present experimental study was Performed to investigate the time change of the median frequency and the muscle torque during maximal isometric back extension exercises at different exercise angles (0$^{\circ}$, 12$^{\circ}$, 36$^{\circ}$and 72$^{\circ}$) Twenty heath subjects (mean age : 24.35 $\pm$ 2.70) were Participated in this study Median frequency was extracted from EMG signals by employing the fast Fourier transform. Initial median frequency and the slope of median frequency was not significantly correlated with the muscle torque. Pearson's Product moment correlation was used to quantify the relationship between slopes of median frequency and torque. The results may suggest that the exorcise angle during maximal isometric back extension exercises does not affect the slopes of the median frequency and torque, and y-intercept of the median frequency among exercise angles There was no significant correlation between slopes of median frequency and torque. But there was a moderate correlation between median frequency and torque at each exercise angle. In conclusion, the exercise angle during maximal isometric back extension exercise is not a direct effect on slopes of median frequency and torque. But results showed that the shift of median frequency and torque shift were highly correlated in all subjects.