• Title/Summary/Keyword: False-positive rate

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Histopathologic Comparative Study of Aspiration Biopsy Cytology from 139 Thyroid Nodules (갑상선결절(甲狀腺結節)에서의 흡인세포학적(吸引細胞學的) 소견(所見)과 병리조직학적(病理組織學的) 진단(診斷)에 대한 비교연구(比較硏究))

  • Kim Kwang-Chul;Wang Hee-Jung;Suh Yeon-Lim;Chang Surk-Hyo;Lee Hyuck-Sang
    • Korean Journal of Head & Neck Oncology
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    • v.8 no.2
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    • pp.97-105
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    • 1992
  • One hundred and thirty-nine thyroid nodules were evaluated by aspiration biopsy cytology (ABC) and were compared with the postoperative histologic diagnosis during the period from May 1, 1986 through Aug. 31, 1992. The correlation betwen the two diagnoses proved to be comparable with a low incidence of false-negative diagnoses, but with a relatively high incidence of false-positive ones. The sensitivity was 93.5%, specificity 89.6%, false-negative rate 6.5%, false-positive rate 10.4%, positive predictability 87.9%, negative predictability 94.5%, and overall diagnostic accuracy 91.4%.

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Design of T-N2SCD Detection Model based on Time Window (타임 윈도우 기반의 T-N2SCD 탐지 모델 구현)

  • Shin, Mi-Yea;Won, Il-Young;Lee, Sang-Ho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.11
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    • pp.2341-2348
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    • 2009
  • An intrusion detection technique based on host consider system call sequence or system call arguments. These two ways are suitable when system call sequence or order and length of system call arguments are out of order. However, there are two disadvantages which a false positive rate and a false negative rate are high. In this paper we propose the T-N2SCD detection model based on Time Window in order to reduce false positive rate and false negative rate. Data for using this experiment is provided from DARPA. As experimental results, the proposed model showed that the false positive rate and the false negative rate are lowest at an interval of 1000ms than at different intervals.

Availability of urine toxicologic screening tests in the emergency department: focused on illegal drugs (응급실에서 시행한 소변 독성 검사의 유용성: 마약을 중심으로)

  • Lee, Se Kyu;Choi, Sangchun
    • Journal of The Korean Society of Clinical Toxicology
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    • v.19 no.1
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    • pp.24-30
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    • 2021
  • Purpose: In Korea, it is predicted that the proportion of drug abusers among patients visiting the emergency room will soon increase. Several emergency medical institutions in Korea are conducting field urine screening tests for poisoning. In this study, we investigated the characteristics and usefulness of urine toxicology screening tests. Methods: The medical records of patients with positive results for tetrahydrocannabinol and methamphetamine from urine toxicology screening tests at a tertiary university hospital from August 2016 to August 2019 were reviewed retrospectively. The subjects were classified into positive and false-positive groups, and their clinical characteristics were compared and analyzed. Results: Of the 2,026 patients surveyed, 823 patients (40.6%) tested positive for one or more drugs. Among them, 12 cases (0.6%) were positive for methamphetamine and 40 cases (2.0%) were positive for tetrahydrocannabinol. The positive and the false-positive rates for methamphetamine were 66.7% and 33.3%, respectively. The positive and the false-positive rates for tetrahydrocannabinol were 2.5% and 97.5%, respectively. Conclusion: Methamphetamine showed a relatively low false-positive rate in our study. Therefore, this test seemed to assist in diagnosing methamphetamine poisoning when considered together with the present illness and physical examination results. On the other hand, the high false-positive rate for tetrahydrocannabinol tests indicates that this test was unlikely to assist in diagnosing tetrahydrocannabinol poisoning. However, considering the growing trend of illegal drug abusers in Korea, it may still be useful as a diagnostic tool for identifying drug users.

Bivariate ROC Curve and Optimal Classification Function

  • Hong, C.S.;Jeong, J.A.
    • Communications for Statistical Applications and Methods
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    • v.19 no.4
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    • pp.629-638
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    • 2012
  • We propose some methods to obtain optimal thresholds and classification functions by using various cutoff criterion based on the bivariate ROC curve that represents bivariate cumulative distribution functions. The false positive rate and false negative rate are calculated with these classification functions for bivariate normal distributions.

High Resolution Melting Analysis for Epidermal Growth Factor Receptor Mutations in Formalin-fixed Paraffin-embedded Tissue and Plasma Free DNA from Non-small Cell Lung Cancer Patients

  • Jing, Chang-Wen;Wang, Zhuo;Cao, Hai-Xia;Ma, Rong;Wu, Jian-Zhong
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6619-6623
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    • 2013
  • Background:The aim of the research was to explore a cost effective, fast, easy to perform, and sensitive method for epidermal growth factor receptor (EGFR) mutation testing. Methods: High resolution melting analysis (HRM) was introduced to evaluate the efficacy of the analysis for dectecting EGFR mutations in exons 18 to 21 using formalin-fixed paraffin-embedded (FFPE) tissues and plasma free DNA from 120 patients. Results: The total EGFR mutation rate was 37.5% (45/120) detected by direct sequencing. There were 48 mutations in 120 FFPE tissues assessed by HRM. For plasma free DNA, the EGFR mutation rate was 25.8% (31/120). The sensitivity of HRM assays in FFPE samples was 100% by HRM. There was a low false-positive mutation rate but a high false-negative rate in plasma free DNA detected by HRM. Conclusions: Our results show that HRM analysis has the advantage of small tumor sample need. HRM applied with plasma free DNA showed a high false-negative rate but a low false-positive rate. Further research into appropriate methods and analysis needs to be performed before HRM for plasma free DNA could be accepted as an option in diagnostic or screening settings.

An Analysis on the Error Probability of A Bloom Filter (블룸필터의 오류 확률에 대한 분석)

  • Kim, SungYong;Kim, JiHong
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.24 no.5
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    • pp.809-815
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    • 2014
  • As the size of the data is getting larger and larger due to improvement of the telecommunication techniques, it would be main issues to develop and process the database. The bloom filter used to lookup a particular element under the given set is very useful structure because of the space efficiency. In this paper, we introduce the error probabilities in Bloom filter. Especially, we derive the revised false positive rates of the Bloom filter using experimental method. Finally we analyze and compare the original false positive probability of the bloom filter used until now and the false decision probability proposed in this paper.

Statistical Analysis of Count Rate Data for On-line Seawater Radioactivity Monitoring

  • Lee, Dong-Myung;Cong, Binh Do;Lee, Jun-Ho;Yeo, In-Young;Kim, Cheol-Su
    • Journal of Radiation Protection and Research
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    • v.44 no.2
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    • pp.64-71
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    • 2019
  • Background: It is very difficult to distinguish between a radioactive contamination source and background radiation from natural radionuclides in the marine environment by means of online monitoring system. The objective of this study was to investigate a statistical process for triggering abnormal level of count rate data measured from our on-line seawater radioactivity monitoring. Materials and Methods: Count rate data sets in time series were collected from 9 monitoring posts. All of the count rate data were measured every 15 minutes from the region of interest (ROI) for $^{137}Cs$ ($E_{\gamma}=661.6keV$) on the gamma-ray energy spectrum. The Shewhart ($3{\sigma}$), CUSUM, and Bayesian S-R control chart methods were evaluated and the comparative analysis of determination methods for count rate data was carried out in terms of the false positive incidence rate. All statistical algorithms were developed using R Programming by the authors. Results and Discussion: The $3{\sigma}$, CUSUM, and S-R analyses resulted in the average false positive incidence rate of $0.164{\pm}0.047%$, $0.064{\pm}0.0367%$, and $0.030{\pm}0.018%$, respectively. The S-R method has a lower value than that of the $3{\sigma}$ and CUSUM method, because the Bayesian S-R method use the information to evaluate a posterior distribution, even though the CUSUM control chart accumulate information from recent data points. As the result of comparison between net count rate and gross count rate measured in time series all the year at a monitoring post using the $3{\sigma}$ control charts, the two methods resulted in the false positive incidence rate of 0.142% and 0.219%, respectively. Conclusion: Bayesian S-R and CUSUM control charts are better suited for on-line seawater radioactivity monitoring with an count rate data in time series than $3{\sigma}$ control chart. However, it requires a continuous increasing trend to differentiate between a false positive and actual radioactive contamination. For the determination of count rate, the net count method is better than the gross count method because of relatively a small variation in the data points.

Design of Web based ID Traffic Analysis System (웹기반의 침입탐지 트래픽 분석 시스템 설계)

  • 한순재;오창석
    • Proceedings of the Korea Contents Association Conference
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    • 2003.11a
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    • pp.144-148
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    • 2003
  • A general administrator's response ability plunged in confusion as intrusion detection system like an existing Snort display much alert messages on administrator's screen. Also, there are some possibilities to cause false positive. In this paper, to solve these problems, we designed Web-based ID(Intrusion Detection) traffic analysis system using correlation, and implemented so that administrator can check easily whole intrusion traffic state in web which dividing into normal and intrusion traffic using Libpcap, Snort, ACID, Nmap and Nessus. As a simulation result, it is proved that alert message number and false positive rate are minimized.

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A Highly Reliable Fall Detection System for The Elderly in Real-Time Environment (실시간 환경에서 노인들을 위한 고신뢰도 낙상 검출 시스템)

  • Lee, Young-Sook;Chung, Wan-Young
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.2
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    • pp.401-406
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    • 2008
  • Fall event detection is one of the most common problems for elderly people, especially those living alone because falls result in serious injuries such as joint dislocations, fractures, severe head injuries or even death. In order to prevent falls or fall-related injuries, several previous methods based on video sensor showed low fall detection rates in recent years. To improve this problem and outperform the system performance, this paper presented a novel approach for fall event detection in the elderly using a subtraction between successive difference images and temporal templates in real time environment. The proposed algorithm obtained the successful detection rate of 96.43% and the low false positive rate of 3.125% even though the low-quality video sequences are obtained by a USB PC camera sensor. The experimental results have shown very promising performance in terms of high detection rate and low false positive rate.

Intrusion Detection for Black Hole and Gray Hole in MANETs

  • She, Chundong;Yi, Ping;Wang, Junfeng;Yang, Hongshen
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.7 no.7
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    • pp.1721-1736
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    • 2013
  • Black and gray hole attack is one kind of routing disturbing attacks and can bring great damage to the network. As a result, an efficient algorithm to detect black and gray attack is important. This paper demonstrate an adaptive approach to detecting black and gray hole attacks in ad hoc network based on a cross layer design. In network layer, we proposed a path-based method to overhear the next hop's action. This scheme does not send out extra control packets and saves the system resources of the detecting node. In MAC layer, a collision rate reporting system is established to estimate dynamic detecting threshold so as to lower the false positive rate under high network overload. We choose DSR protocol to test our algorithm and ns-2 as our simulation tool. Our experiment result verifies our theory: the average detection rate is above 90% and the false positive rate is below 10%. Moreover, the adaptive threshold strategy contributes to decrease the false positive rate.