• Radiation Oncology Journal
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• v.36 no.2
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• pp.103-113
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• 2018

Purpose: Anaplastic thyroid cancer (ATC) is a rare tumor with a lethal clinical course despite aggressive multimodal therapy. Intensity-modulated radiotherapy (IMRT) may achieve a good therapeutic outcome in ATC patients, and the role of IMRT should be assessed. We retrospectively reviewed outcomes for ATC treated with three-dimensional conformal radiotherapy (3D-CRT) or IMRT to determine the optimal treatment option and explore the role of radiotherapy (RT). Materials and Methods: Between December 2000 and December 2015, 41 patients with pathologically proven ATC received RT with a sufficient dose of ${\geq}40Gy$. Among them, 21 patients (51%) underwent surgery before RT. Twenty-eight patients received IMRT, and 13 received 3D-CRT. Overall survival (OS) and progression-free survival (PFS), patterns of failure, and toxicity were examined. Results: The median follow-up time for survivors was 38.0 months. The median and 1-year OS and PFS rates were 7.2 months and 29%, 4.5 months and 15%, respectively. Surgery significantly improved the prognosis (median OS: 10.7 vs. 3.9 months, p = 0.001; median PFS: 5.9 vs. 2.5 months, p = 0.007). IMRT showed significantly better PFS and OS than 3D-CRT, even in multivariate analysis (OS: hazard ratio [HR] = 0.30, p = 0.005; PFS: HR = 0.33, p = 0.005). Significantly higher radiation dose could be delivered with IMRT than 3D-CRT ($EQD2_{10}$ 66 vs. 60 Gy, p = 0.005). Only 2 patients had grade III dermatitis after IMRT. No other severe toxicity ${\geq}grade$ III occurred. Conclusion: Patients with ATC showed better prognosis through multimodal treatment. Furthermore, IMRT could achieve favorable survival rates by safely delivering higher dose than 3D-CRT.

• Korean Journal of Medicinal Crop Science
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• v.23 no.3
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• pp.223-230
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• 2015

To study the effect of crop rotation on the control of ginseng root rot, growth characteristics and root rot ratio of 2-year-old ginseng was investigated after the crops of 18 species were cultured for one year in soil contaminated by the pathogen of root rot. Fusarium solani and Cylindrocarpon destructans were detected by 53.2% and 37.7%, respectively, from infected root of 4-year-old ginseng cultivated in soil occurring the injury by continuous cropping. Content of $NO_3$, Na, and $P_2O_5$ were distinctly changed, while content of pH, Ca, and Mg were slightly changed when whole plant of crops cultured for one year were buried in the ground. All of EC, $NO_3$, $P_2O_5$, and K were distinctly increased in soil cultured sudangrass, peanut, soybean, sunnhemp, and pepper. All of EC, $NO_3$, $P_2O_5$, and K among inorganic component showed negative effect on the growth of ginseng when they were excessively applied on soil. The growth of ginseng was promoted in soil cultivated perilla, sweet potato, sudangrass, and welsh onion, while suppressed in Hwanggi (Astragalus mongholicus), Deodeok (Codonopsis lanceolata) Doraji (Platycodon grandiflorum), Gamcho (Glycyrrhiza uralensis), Soybean. All of chicory, lettuce, radish, sunnhemp, and welsh onion had effective on the inhibition of ginseng root rot, while legume such as soybean, Hwanggi, Gamcho, peanut promoted the incidence of root rot. Though there were no significant correlation, $NO_3$ showed positive correlation, and Na showed negative correlation with the incidence of root rot.

• Journal of the Korea institute for structural maintenance and inspection
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• v.18 no.6
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• pp.60-71
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• 2014

Cable-stayed bridge, which is one of the representative long-spanned bridge, needs prompt maintenances when a stay cable is damaged because it may cause structural failure of the entire bridge. Many researches are being conducted to develop abnormal behavior detection algorithms for the purpose of shortening the reaction time after the occurrence of structural damage. To improve the accuracy of the damage detection algorithm, ample observation data from various kinds of damage responses is needed. However, it is difficult to measure an abnormal response by damaging an existing bridge, numerical simulation can be an effective alternative. In most previous studies, which simulate the damage responses of a cable-stayed bridge, the damages has been considered as a load variation without regard to its stiffness variation. The analyses of using these simplification could not calculate exact responses of damaged structure, though it may reserve a sufficient accuracy for the purpose of bridge design. This study suggests Gradual Bilinear Method (GBM) which simulate the damage responses of cable-stayed bridge considering the stiffness and mass variation, and develops an analysis program. The developed program is verified from the responses of a simple model. The responses of a existing cable-stayed bridge model are analyzed with respect to the fracture delay time and damage ratio. The results of this study can be used to develop and verify the highly accurate abnormal behavior detection algorithm for safety management of architecture/large structures.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.34 no.6
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• pp.1677-1685
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• 2014

Short discrete fibers compounded with concrete can enhance the tensile resistance and ductility of concrete. Recently, the effectiveness of the reinforcement has increased according to the increasing length of steel fiber. However, the lengthening of steel fiber requires reducing the ratio of the fiber content to remain the workability and quality of concrete. Thus, the present study evaluated the flexural performance of fiber reinforced concrete with less than l.0% fiber volume ratios of steel fiber, 30mm and 60mm long, and polypropylene fiber, being evaluated as a good reinforcing material with chemical stability, long-term durability, and cost effectiveness. Concrete with more than 0.25% steel and 0.5% polypropylene fibers improved the brittle failure of concrete after reaching cracking strength. Concrete reinforced with polypropylene exhibited deflection-softening behavior, but that with more than 0.5% polypropylene delayed stress reduction and recovered flexural strength by 60 to 80% after cracking strength. In conclusion, concrete reinforced with more than 0.75% polypropylene could improve structural flexural performance. In particular, energy absorption capacity of reinforced concrete with 1.0% polypropylene fiber was similar to that with 0.5% and 0.7% steel fibers.

• Journal of the Korea Concrete Institute
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• v.13 no.3
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• pp.261-267
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• 2001

The objective of this experimental study is to find the allowable level of axial load to give the proper flexural ductility according to the yield strength of lateral ties, and the distribution and amount of longitudinal bars used in confined high-strength concrete columns. Twelve concrete columns with a 20 cm square section and 80 cm high were tested under hi-axial loads. It was observed that the ductility tends to be improved at the axial loads not less than 0.4f$\_$ck/A$\_$g/. The utilization of high-strength ties in accordance with the ACI 318-99 can cause the brittle failure due to the wide tie spacing. Under the high level of axial loads not less than 0.4f$\_$ck/A$\_$g/. it is necessary for the buckling prevention of the longitudinal bars and the proper ductility improvement to use the high-strength ties with the consideration of the volumetric ratio and confinement type of the lateral ties, and the distribution of the longitudinal bars.

• Journal of the Korea Concrete Institute
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• v.25 no.2
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• pp.217-224
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• 2013

Design provisions for the development length of headed bars in ACI 318-08 include concrete compressive strength and yield strength of headed bars as design parameters but do not consider the effects of transvers reinforcement. In addition, they have very strict limitation for clear spacing and material strengths because these provisions were developed based on limited tests. In this study, splice tests using SD600 headed bars with $2d_b$ clear spacing and transverse reinforcement were conducted. Test results show that unconfined specimens failed due to prying action and bottom cover concrete prematurely spalled. The contribution of head bearing on the anchorage strength is only 15% on average implying that unconfined specimens failed before the head bearing was not sufficiently developed. Confined specimens with stirrups placed along whole splice length have enhanced strengths in bearing as well as bond because the stirrups prevented prying action and improved bond capacity. Bond failure occurred in locally confined specimens where stirrups were placed only at the ends of splice length. The stirrups at ends of splice lengths can prevent prying action but the bond capacity did not increase. From regression analysis of test results, an equation to predict anchorage strength of headed bars was developed. The proposed equation consists of bond and bearing contributions and includes transverse reinforcement index. The average ratio of tests to predictions is 1.0 with coefficient of variation of 6%.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.29 no.5
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• pp.383-393
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• 2007

The aim of the present study is to investigate the effect of anodized surface of osseointegration implants by using of resonance frequency analysis (RFA) and histomorphometric analysis. A total of 96 screw-shaped implants were devided into 4 groups. Seventy-two implants were prepared by electrochemical oxidation with 3 different ways; Group 1 (n=24) were prepared at galvanostatic mode in 0.25M sulfuric acid and phosphoric acid, Group 2 (n=24) were prepared at galvanostatic mode in calcium glycerophosphate and calcium acetate, and Group 3 (n=24) were prepared at galvanostatic mode in 0.25M sulfuric acid and phosphoric acid followed by Calcium metaphosphate(CMP) coating. Control group (n=24) were the RBM surfaced implants. The implants were placed in the mandibles of 12 mini pigs. Bone tissue responses were evaluated by resonance frequency analysis(RFA) and histomorphometric analysis that were undertaken at 2, 4 and 6weeks after implant placement. The following result were obtained. 1. Twenty-two of 96 implants (4 in control group, 5 in group 1, 7 in group 2, and 6 in group 3) were failed due to faliure of osseoitegration. The failure rate of osseointegration was 22.9%. 2. The mean values of RFA in control, group 2 and groups 3 showed the similar values, but there was no significant difference among groups. 3. Histomorphometric evaluation demonstrated significantly higher bone-to-implant contact ratio in group 2 at 3 and 4 weeks after implant placement than other groups (p<0.05), but there was no significant difference among groups at 6weeks after implant placement.

• Journal of the Korea Society of Computer and Information
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• v.25 no.2
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• pp.221-229
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• 2020

As the cosmetics beauty industry grows into a key next-generation industry, the establishment of an industrialization center is needed, but failure to verify the adequacy and feasibility of the investment could lead to financial burdens. In this study, the project costs and facilities of an industrial center are reviewed to analyze its economic feasibility based on the cost estimates, revenue estimates, estimated profit or loss calculations, and estimated operating cash flows. The profit estimation criteria were analyzed by applying 90 per cent of expected orders for research projects (24 billion won) and 12 per cent of rental rates for testing equipment (4.5 billion won for construction), and the benefit/cost ratio is higher than 1.02 per cent and the net present value is higher than '0' won, and the internal rate of return is also more than 5.06 per cent for all three analytical methods. Therefore, in order for the construction of a cosmetics beauty industrialization center to be economically feasible, it is necessary to maintain research project orders of more than 90 percent and return on equipment rent of more than 12 percent, and a strategic approach is needed to diversify business profits.

• Korean Journal of Clinical Laboratory Science
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• v.38 no.3
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• pp.208-211
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• 2006

Microalbuminuria is most frequently caused by kidney damage from diabetes. Moreover, many other conditions can lead to kidney damage, such as high blood pressure, heart failure, cirrhosis, or systemic lupus erythematosus (SLE). The measurement of the microalbumin in urine may be useful for the early diagnosis or as a predictor of nephropathy in diabetes. The most common method for getting a quantitative measurement of urinary protein relies on a 24-hour urine collection. The result of this method is accurate. But 24hr urine collection is difficult to obtain and variations in volume are frequent. Also the patients complain about urine collection. We tried to measure reference values for microalbumin using fasting urine and compare them with the albumin/creatinine ratio using 24hr urine. The concentrations of microalbumin in fasting urine and 24hr urine were $7.1{\pm}3.8mg/L$, $5.7{\pm}2.9mg/L$ (r=0.61, p=0.27), respectively. The albumin/creatinine ratios using fasting urine and 24hr urine were $8.7{\pm}4.2{\mu}g/mg$, $8.7{\pm}4.0{\mu}g/mg$ (r=0.76, p=0.88), respectively. This study indicated that the measurement of microalbumin in fasting urine was an easy and simple method for early diagnosis or to predict nephropathy in diabetes. Thus, setting up the reference value using fasting urine may be useful in the screening test for the diabetic nephropathy patients instead of using the 24hr albumin excretion rate (AER).

• Geotechnical Engineering
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• v.9 no.4
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• pp.103-118
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• 1993

This paper presents the results of investigation of the rainstorm induced landslides occurred in the districts of Yongin, Ansung and Osan on July 21st 1991. More than two thousand and sirs hundred landsilides took place during or after a 3-t hours heavy rainfall and about 466 ha mountain slopes were affected by slope failures. The result of study on the effect of-iainfall on landslides shows that landslides began to occur where daily and maximum hourly rainfall exceeded 114mm and 40mm respectively, and all districts (myun) where maximum hourly rainfall exceeded 62mm were affected by landslides. The morphological study on landslides on Talbongsan area reveals that, by Walker's classi fication using D IL(failure depth ratio), 50% of the landslides were classified as flows, 20% of them as translational slides, and 30% were between flow and slide and there were few rotational slides. Over 90% of landslides tookplace at slopes of 20$^{\circ}$-40$^{\circ}$ in slope and 50m or shorter in length And more than 50% of the crown of slides locates at higher than 0.7 times of slope hight. Any differences between the kinds of tree in landslide resisting effects are shown in this case.