• Title/Summary/Keyword: Failure Life

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Pharmacokinetics of Sulfamethoxazole in Rabbits with Experimental Renal Failure (실험적 신장장해 가토에서 설파메톡사졸의 약물동태학적 연구)

  • Choi, Jun-Shik;Lee, Chong-Ki
    • Journal of Pharmaceutical Investigation
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    • v.16 no.4
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    • pp.152-157
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    • 1986
  • The pharmacokinetics of sulfamethoxazole were investigated in rabbits with folate-induced renal failure. The blood level, area under the blood concentration curve (AUC) and biological half-life were increased significantly, and the urinary excretion was decreased significantly compared with those of normal rabbits. Correlation of serum creatinine concentration and AUC, biological half-life, and correlation of creatinine clearance and renal clearance have linear relationship respectively. From these results, dosage regimen of sulfamethoxazole is considered to be adjusted for effective and safe therapy in renal failure.

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Reliability Evaluation of Thruster Break for Aerogenerator (풍력발전기용 쓰러스터 브레이크의 신뢰성 평가)

  • Jung, Dong Soo
    • Journal of Applied Reliability
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    • v.13 no.3
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    • pp.165-174
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    • 2013
  • Thruster break for aerogenerator performs a role that is stopping the rotor in case of emergency such as strong wind, system abnormality or maintenance check. In this study, failure analysis and test evaluation on the thruster break for aerogenerator are proposed, and the entire process to improve reliability of the product through design improvement is presented. The typical failure case is fatigue and wear, and failure cause on these are identified and improvement plan is presented. Lastly, reliability improvement is established to analyse test results before after the life test.

Fatigue failure of decks in highway bridge (도로교 RC 바닥판의 피로파괴에 관한 연구)

  • 김경찬;사림신장;정상정일;권혁문
    • Proceedings of the Korea Concrete Institute Conference
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    • 1993.04a
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    • pp.169-175
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    • 1993
  • Possibility of fatigue failure in punching shear of reinforced concrete decks of highway bridges is analytically investigated by applying Matsui et al.'s experimental finding to models of 2-meter span decks designed in compliance with previous and current codes. Decks made of concrete of compressive strength of 240㎏/㎠ showed longer fatigue life than decks made of 210㎏/㎠ concrete at the same Md/U rations ; higher Md/U ratio resulted in linger fatigue life but its effect is insignificant in decks having effective depths of 14 and 15cm. Decks designed to higher load factors as specified by current codes showed longer fatigue life than decks designed to lower load factors specified by previous codes ; yet fatigue failure appeared to occur in both decks within their normal life span, thus indicating need for redefining the minimum deck thickness.

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Reliability Assessment of Elevators Using Life Data of the Components (부품의 수명 데이터를 이용한 승강기의 신뢰성 평가)

  • Sohn, S.H.;Sohn, H.J.;Kim, S.J.;Yang, B.S.;Yoon, M.C.
    • Journal of Power System Engineering
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    • v.14 no.6
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    • pp.61-66
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    • 2010
  • Engineering asset management (EAM) requires the accurate assessment of current and the prediction of future asset health condition. Suitable mathematical models that are capable of predicting time-to-failure and the probability of failure in future time are essential. In general reliability models, lifetime of component and system is estimated using failure time data. This paper deals with the reliability assessment of elevators using life of main components. Especially this work is concerned with the stochastic nature of life of elevator components. First, we investigate the Weibull statistical analysis of lifetime data for the components. The final goal is to establish the mathematical model for reliability assessment. This work provides more perspectives to future research in the fields of reliability and maintainability.

Probabilistic Assessment of life Time for Gas Pipe Lines (통계적 방법을 통한 가스배관의 잔여수명 예측)

  • Choe, B.H.;Lee, S.H.;Kim, Y.P.;Kim, W.S.;Ko, Y.T.
    • Proceedings of the KSME Conference
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    • 2004.04a
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    • pp.234-239
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    • 2004
  • A study on the probabilistic methodology for the estimation of the remaining life of Pressurized pipelines containing active corrosion defects is presented. This reliability assessment is earned out using extream value distribution of the corroded defects instead of already published failure perssure moded like NG18 or ASME B31G. The failure probability of pipelines depends on the number of corroded defects. and it could be calculated directly as the area exceeded a defined L V(Limited Value of corrosion depth). The remaining life of pressurized pipelines can also be estimated by the PDF of extream value distribution as calculating the exceeded area with a defined failure probability.

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A Service Life Prediction for Joint and Cracked Concrete Exposed to Carbonation Based on Stochastic Approach (신뢰성 해석을 통한 탄산화에 노출된 타설이음부 및 균열부 콘크리트의 내구수명 평가)

  • Kwon, Seung-Jun;Park, Sang-Sun;Lee, Sang-Min
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.11a
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    • pp.597-600
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    • 2006
  • In this study, field survey of carbonation for RC column in city is carried out and carbonation behavior in sound, joint, and cracked concrete is also analyzed. Futhermore, probability of durability failure with time is calculated through considering probability variables such as concrete cover depth and carbonation depth which are obtained from field survey. The probability of durability failure in cracked concrete with considering crack width and time is also calculated and service life is predicted based on intended failure probability in domestic specification. Through this study, it is known that service life in a RC column is evaluated differently for local conditions and each service life is rapidly decreased with decrease in cover depth and increase in crack width.

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The Estimation of Shape Parameter of Pneumatic Cylinders (공압 실린더의 신뢰성 평가를 위한 형상모수 추정에 관한 연구)

  • Kang, B.S.;Song, C.S.
    • Journal of Power System Engineering
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    • v.10 no.4
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    • pp.127-132
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    • 2006
  • Pneumatic cylinders that are usually applied in the factory automation line have complicated failure cause because they are composed of various elements. In this study, we performed life test and performance test of double acting pneumatic cylinders according to the international standards and then analyzed the life and the main failure mode of the cylinders in the same load condition. On the basis of these processes, we can estimate shape parameter for the reliability estimation of pneumatic cylinders and their data analysis of life distribution.

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A Study on Friction and Wear of TiN Film for the Wear-life Prediction (마모수명평가를 위한 TiN 경질박막의 마찰 및 마모특성에 관한 연구)

  • 정기훈;이영제
    • Tribology and Lubricants
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    • v.13 no.3
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    • pp.28-32
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    • 1997
  • Indentation, scratch and sliding tests were carried out in this paper to predict the critical loads and the failure modes of TiN-coated specimen. The test specimens were S20C steels with three different substrate hardness, roughness and coating thickness. The scratch test shows that the coating thickness has more dominant effect on the critical load of coated disk than the hardness and the roughness. Using the percent contact load, the ratio of sliding load to the critical scratch load, the cycles to failure are measured to predict the wear-life of TiN film. On the wear-life diagram the percent loads and the cycle to failure show the good linear relation on semi-log coordinate. With decreasing loads, the diagram shows the wear-limit at which the coated disk survives more than 4000 cycles.

Study on the Analysis of Failure Cause and Determination of Life Test Mode of Capsule (축열조 캡슐 고장원인 분석과 수명시험 모드 결정에 관한 연구)

  • Kang, Bosik;Lee, Yongbum;Jung, Dongsoo;Lee, Chungsung
    • Journal of Applied Reliability
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    • v.18 no.3
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    • pp.260-270
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    • 2018
  • Purpose: The purpose of this study is to evaluate the life of the capsule, which is a core part of the heat storage cooling system. This paper will develop a life test mode that can reproduce environment conditions through the analysis of capsule shrinkage and expansion characteristics. Methods: In order to determine the life test mode of the capsule, this paper analyzed the case of field failures and analyzed the deformation characteristics according to the pressure fluctuation of the capsule. The method to find out whether the field failure and deformation analysis results are consistent is the testing with the construction of the repetition pressure test equipment and the thermal cycle test to reproduce the freezing and thawing characteristics. Results: In this study, failure mode analysis and analysis of freezing and thawing characteristics regarding to the capsule positions were completed. Based on this test & analysis results, this paper have been able to determine the main parameters for determining the life test mode, the freezing and thawing time. Conclusion: Determining the lifetime mode of the capsule can be used to improve the life and performance of the thermal storage system.