• Proceedings of the Korean Geotechical Society Conference
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• 2008.10a
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• pp.508-518
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• 2008

Reliability and sensitivity analysis of the design parameters for a section of caisson type quaywall which is the most applicable in Korea were performed. It was tried to estimate probabilities of failure for the system of the multiple failure modes and to analyze LCC in the quaywall structure. The reliability analysis was performed by FORM. Also, sensitivity indices were estimated using the reliability indices, which may be used inferring effects of each design parameter on the reliability indices. As a result, the coefficient of friction between caisson and rubble, the moment by self weight and the moment of resistance mostly affected on the reliability indices in the sliding, overturning and foundation failure, respectively. System reliability theorem was applied in order to estimate the probabilities of failure for the system of the multiple failure modes. As the results of estimation of the probabilities of failure for the system, all cases were more conservative than those for the elements, according to both failure mode and load combination applied to series system. It entirely exceeded the target reliability index, but it was consistent with the theorem. According to the optimum LCC with the width of the caisson, the probability of failure exceeded the target probability of failure at then time. Therefore, it was judged to be insufficient to the practical application.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.54 no.11
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• pp.548-556
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• 2005

Reliability evaluation of power distribution system is very important to both power utilities and customers. It present the probabilistic number and duration of interruption such as failure rate, SATDI, SAIFI, and CAIDI. However, it has a fatal weakness at reliability index because of accuracy of failure rate. In this paper, the Time-varying Failure Rate(TFR) of power distribution system equipment is extracted from the recorded failure data of KEPCO(Korea Electric Power Corporation) in Korea. For TFR extraction, it is used that the fault data accumulated by KEPCO during 10 years. The TFR is approximated to bathtub curve using the exponential(random failure) and Weibull(aging failure) distribution function. In addition, Kaplan-Meier estimation is applied to TFR extraction because of incomplete failure data of KEPCO. Finally, Probability plot and regression analysis is applied. It is presented that the extracted TFR is more effective and useful than Mean Failure Rate(MfR) through the comparison between TFR and MFR

• Geomechanics and Engineering
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• v.29 no.2
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• pp.193-205
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• 2022

The face stability of shield tunnelling is the most important control index for safety risk management. Based on the reliability of the transparent clay (TC) model test, a series of TC model tests under different buried depth were conducted to investigate the progressive failure mechanism of tunnel face. The support pressure was divided into the rapid descent stage, the slow descent stage and the basically stable stage with company of the local failure and integral failure in the internal of the soil during the failure process. The relationship between the support pressure and the soil movement characteristics of each failure stage was defined. The failure occurred from the soil in front of the tunnel face and propagated as the slip zone and the loose zone. The fitted formulas were proposed for the calculation of the failure process. The failure mode in clay was specified as the basin shape with an inverted trapezoid shape for shallow buried and appeared as the basin shape with a teardrop-like shape in deep case. The implications of these findings could help in the safety risk management of the underground construction.

• Smart Structures and Systems
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• v.16 no.2
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• pp.367-382
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• 2015

This paper aims to conduct the reliability-based assessment of the welded joint in the orthotropic steel bridge deck by use of a mesh-insensitive structural stress (MISS) method, which is an effective numerical procedure to determine the reliable stress distribution adjacent to the weld toe. Both the solid element model and the shell element model are first established to investigate the sensitivity of the element size and the element type in calculating the structural stress under different loading scenarios. In order to achieve realistic condition assessment of the welded joint, the probabilistic approach based on the structural reliability theory is adopted to derive the reliability index and the failure probability by taking into account the uncertainties inherent in the material properties and load conditions. The limit state function is formulated in terms of the structural resistance of the material and the load effect which is described by the structural stress obtained by the MISS method. The reliability index is computed by use of the first-order reliability method (FORM), and compared with a target reliability index to facilitate the safety assessment. The results achieved from this study reveal that the calculation of the structural stress using the MISS method is insensitive to the element size and the element type, and the obtained structural stress results serve as a reliable basis for structural reliability analysis.

• Computers and Concrete
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• v.18 no.6
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• pp.1175-1194
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• 2016

Nonlinear models, capable of taking into account all the phenomena involved in the cracking and in the failure of lightly reinforced concrete beams, are nowadays available for a rigorous calculation of the minimum reinforcement. To simplify the current approaches, a new procedure is proposed in this paper. Specifically, the ductility index, which is lower than zero for under-reinforced concrete beams in bending, is introduced. The results of a general model, as well as the data measured in several tests, reveal the existence of two linear relationships between ductility index, crack width, and the amount of steel reinforcement. The above relationships can be applied to a wide range of lightly reinforced concrete beams, regardless of the geometrical dimensions and of the mechanical properties of materials. Accordingly, if only a few tests are combined with this linear relationships, a new design-by-testing procedure can be used to calculate the minimum reinforcement, which guarantees both the control of cracking in service and the ductility at failure.

• Investigative Magnetic Resonance Imaging
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• v.21 no.3
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• pp.125-130
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• 2017

Purpose: To evaluate the clinical significance of T1 high signal intensity on the globus pallidus as a predictor of severe hepatic encephalopathy in patients with acute-on-chronic liver failure (ACLF), which is a distinct syndrome characterized by multi-organ dysfunction including cerebral failure. Materials and Methods: From January 2002 to April 2014, we retrospectively reviewed the magnetic resonance imaging (MRI) findings and clinical and magnetic resonance (MR) features of 74 consecutive patients (44 men and 30 women; mean age, 59.5 years) with liver cirrhosis. The chronic liver failure-sequential organ failure assessment score was used to diagnose ACLF. The pallidal index (PI), calculated by dividing the mean signal intensity of the globus pallidus by that of the subcortical frontal white matter were compared according to ACLF. The PI was compared with the Model for End-Stage Liver Disease (MELD) score in predicting the development of ACLF. Results: Fifteen patients who were diagnosed with ACLF had higher hepatic encephalopathy grades (initial, P = 0.024; follow-up, P = 0.002), MELD scores (P < 0.001), and PI (P = 0.048). In the ACLF group, the mean PI in patients with cerebral failure was significantly higher than that in the patients without cerebral failure (1.33 vs. 1.20, P = 0.039). In patients with ACLF, the area under the curve (AUC) for PI was 0.680 (95% confidence intervals [CI], 0.52-0.85), which was significantly lower than that for the MELD score (AUC, 0.88; 95% CI, 0.77-0.99) (P = 0.04). Conclusion: The PI can be an ancillary biomarker for predicting the development of ACLF and severe hepatic encephalopathy.

• Korean Journal of Acupuncture
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• v.20 no.2
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• pp.55-66
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• 2003

Objectives : The aim of this experiment is to investigate the effects of moxibustion on SP6, Sp9 and BL28 in uranyl acetate-induced acute renal failure in rats. Methods : To induce experimental acute renal failure, uranyl acetate was intraperitoneally injected to rats by 5mg/kg. 3 days later moxibustion treatment was done at SP6, Sp9 and BL28 bilaterally of the rats. And then 4 days later, we measured rats' body weight, kidney weight, serum BUN, creatinine and serum electrolytic levels(Na, K and Cl). Results : In the SP6 group, serum BUN were significantly decreased (p<0.01). In the BL28 group, serum Na level were significantly decreased (p<0.05). In the $SP6{\cdot}SP9$ group, serum creatinine level were significantly increased but serum Na level, serum Cl level were significantly decreased(p<0.05). In the $SP6{\cdot}BL28$ group, hypertrophy index of kidney and serum creatinine level were significantly decreased(p<0.01) and serum BUN were marginally significantly decreased (0.1

• Structural Engineering and Mechanics
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• v.86 no.3
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• pp.385-397
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• 2023

This study presents an experiment and analysis to compare the seismic behavior of full-scale reinforced concrete beam-column joint strengthened by prestressed steel strips, externally bonded steel plate, and CFRP sheets. For experimental investigation, five specimens, including one joint without any retrofitting, one joint retrofitted by externally bonded steel plate, one joint retrofitted by CFRP sheets, and two joints retrofitted by prestressed steel strips, were tested under cyclic-reserve loading. The failure mode, strain response, shear deformation, hysteresis behavior, energy dissipation capacity, stiffness degradation and damage indexes of all specimens were analyzed according to experimental study. It was found that prestressed steel strips, steel plate and CFRP sheets improved shear resistance, energy dissipation capacity, stiffness degradation behavior and reduced the shear deformation of the joint core area, as well as changed the failure pattern of the specimen, which led to the failure mode changed from the combination of flexural failure of beams and shear failure of joints core to the flexural failure of beams. In addition, the beam-column joint retrofitted by steel plate exhibited a high bearing capacity, energy consumption capacity and low damage index compared with the joint strengthened by prestressed steel strip, and the prestressed steel strips reinforced joint showed a high strength, energy dissipation capacity and low shear deformation, stirrups strains and damage index compared to the CFRP reinforced joint, which indicated that the frame joints strengthened with steel plate exhibited the most excellent seismic behavior, followed by the prestressed steel strips.

• Journal of the Korean GEO-environmental Society
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• v.15 no.2
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• pp.5-15
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• 2014

Target reliability index in the limit state design indicated the safety margin and it is important to determine the partial factor. To determine the target reliability index which is needed in the limit state design, the six design and construction case histories of gravel compaction piles (GCP) were investigated. The limit state functions were defined by bulging failure for the major failure mode of GCP. The reliability analysis were performed using the first order reliability method (FORM) and the reliability index was calculated for each ultimate bearing capacity formulation. The reliability index of GCP tended to be penportional to the safety factor of allowable stress design and average value was ${\beta}$=2.30. Reliability level that was assessed by reliability analysis and target reliability index for existing structure foundations were compared and analyzed. As a result, The GCP was required a relatively low level of safety compared with deep and shallow foundations and the currd t reliability level were similar to the target reliability in the reinforced earth retaining-wall and soil-nailing. Therefore the target reliability index of GCP suggested as ${\beta}_T$=2.33 by various literatures together with the computed reliability level in this study.

• Journal of Pharmaceutical Investigation
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• v.25 no.3
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• pp.265-270
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• 1995

The pharmacokinetics of norfloxacin (100 mg/kg, oral) in renal failure rabbits was studied. Renal failure rabbits were induced by the i.v. injection of folate (50,100 and 150 mg/kg). These produced significant increases of serum creatinine concentration $(S_{cr})$ and blood urea nitrogen (BUN). Plasma concentration and AUC of norfloxacin significantly increased. Elimination rate constant $(K_{el})$ of norfloxacin significantly decreased, and half-life $(t_{1/2})$ of norfloxacin significantly increased. Correlation between serum creatinine concentration $(S_{cr})$ and half-life $(t_{1/2})$ of norfloxacin, and correlation between BUN and AUC of norfloxacin have linear relationship respectively. These results suggest that adjustment or the dosage regimen of norfloxacin is desirable, and serum creatinine concentration $(S_{cr})$ as well as BUN can be used an index for adjusting the dosage regimen of norfloxacin in renal failure.