• Title/Summary/Keyword: FP activity

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Effect of Change in Degrees of Inclination during Treadmill Gait Training on EEG of Stroke Patients (경사도 각도에 따른 트레드밀 보행훈련 시 뇌졸중 환자의 뇌파에 미치는 영향)

  • Sun-Min Kim;Dong-Hoon Kim;Sang-Hun Jang
    • PNF and Movement
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    • v.22 no.1
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    • pp.139-149
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    • 2024
  • Purpose: This study aimed to investigate the effects of gradually increasing treadmill inclination on the electroencephalogram (EEG) of stroke patients during gait training. Methods: Three stroke patients who were diagnosed with stroke within six months and capable of walking on a treadmill were selected as subjects. EEG electrodes were attached at Fp1, Fp2, F3, F4, C3, C4, P3, and P4 positions of the cerebral hemispheres using the International 10-20 system. The intervention involved walking for 2 minutes each at 0 degrees, 15 degrees, and 30 degrees inclination on the treadmill while focusing on a target point located in front during the treadmill gait training. The EEG (Smartingmobi, Serbia) generated when the treadmill gradient gradually increased was measured. In addition, relative alpha and relative beta waves were visualized through the Brain mapping program in the TeleScan program to assess the changes in each brain region for the activity of the EEG. Results: The relative alpha wave value decreased as treadmill inclination increased, while the relative beta wave value increased. Conclusion: Gradually increasing the inclination during treadmill gait training appears to be a crucial parameter for increasing the brain activity levels of stroke patients.

The Discriminating Nature of Dopamine Transporter Image in Parkinsonism: The Competency of Dopaminergic Transporter Imaging in Differential Diagnosis of Parkinsonism: $^{123}I-FP-CIT$ SPECT Study (도파민운반체 영상의 파킨슨증 감별진단 성능: $^{123}I-FP-CIT$ SPECT 연구)

  • Kim, Bom-Sahn;Jang, Sung-June;Eo, Jae-Seon;Park, Eun-Kyung;Kim, Yu-Kyeong;Kim, Jong-Min;Lee, Won-Woo;Kim, Sang-Eun
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.4
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    • pp.272-279
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    • 2007
  • Purpose: The aim of this study was to evaluate the discriminating nature of $^{123}I-FP-CIT$ SPECT in patients with parkinsonism. Methods: $^{123}I-FP-CIT$ SPECT images acquired from the 18 normal controls; NC ($60.4{\pm}10.0$ yr) and 237 patients with parkinsonism ($65.9{\pm}9.2$ yr) were analyzed. From spatialIy normalized images, regional counts of the caudate, putamen, and occipital lobe were obtained using region of interest method. Binding potential (BP) was calculated with the ratio of specific to nonspecific binding activity at equilibrium. Additionally, the BP ratio of putamen to caudate (PCR) and asymmetric Index (ASI) were measured. Results: BPs of NC $3.37{\pm}0.57,\; 3.10{\pm}0.41,\; 3.23{\pm}0.48$ for caudate, putamen, whole striatum, respectively) had no significant difference with those of essential tremor; ET ($3.31{\pm}0.64,\; 3.06{\pm}0.61,\; 3.14{\pm}0.63$) and Alzheimer's disease; AD (3.33 $\pm$0.60, 3.29$\pm$0.79, 3.31$\pm$0.70), but were higher than those of Parkinson's disease; PD (1.92$\pm$0.74, 1.39$\pm$0.68, 1.64$\pm$0.68), multiple system atrophy; MSA (2.36$\pm$1.07, 2.16$\pm$0.91, 2.26$\pm$0.96), and dementia with Lewy body; DLB (1.95$\pm$0.72, 1.64$\pm$0.65, 1.79$\pm$0.66)(p<0.005). PD had statisticalIy lower values of PER and higher values of ASI than those of NC (p<0.005). And PD had significantIy lower value of PCR, higher ASI and lower BP in the putamen and whole striatum than MSA (p<0.05). Conclusion: Dopamine transporter image of $^{123}I-FP-CIT$ SPECT was a good value in differential diagnosis of parkinsonism.

Effect of Feeding Chemically Treated Mustard (Brassica campestris) Straw on Rumen Fibre Degrading Enzymes in Sheep

  • Vaithiyanathan, S.;Raghuvanshi, S.K.S.;Mishra, A.S.;Tripathi, M.K.;Misra, A.K.;Prasad, R.;Jakhmola, R.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.11
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    • pp.1610-1613
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    • 2003
  • The aim of the experiment was to study the changes in the activities of various rumen fibre degrading enzymes due to the feeding of chemically treated mustard (Brassica campestris) straw in sheep. Mustard straw (MS) (<5 cm particle size) was treated either with urea (4% (w/w), or with 2% sodium hydroxide (NaOH), or with alkaline hydrogen peroxide (2% NaOH and 1.5% hydrogen peroxide ($H_2O_2$)) and/or supplemented with 2% (w/w) urea. Seven maintenance type rations were prepared using MS (70 parts) with molasses (5 parts) and concentrate (25 parts). They were untreated MS (CMS), urea treated MS (UMS), urea supplemented MS (MSUS), alkali treated MS (AMS), alkali treated and urea supplemented MS (AMS-US), alkali $H_2O_2$ treated MS (AHMS) and alkali $H_2O_2$ treated and urea supplemented MS (AHMS-US). They were then compressed into a complete feed block with the help of block making machine. Forty two male hoggets of Malpura breed sheep were equally distributed into each treatment group and (were) offered feed and water ad libitum. At the end of 21 days of feeding trial, rumen liquor was collected through stomach tube from three animals in each group at 0 h, 4 h, 8 h, 12 h of post feeding. Results showed that the level of enzyme varied from 8.52 to 11.12, 40.85 to 50.37, 3.22 to 3.78, 2.09 to 2.77 and 31.44 to 44.24 units/100 ml SRL respectively for carboxymethyl cellulase (CMCase), $\alpha$-amylase, microcrystalline cellulase (MCCase), filter paper (FP) degrading enzyme and $\alpha$-glucosidase. Processing of MS affected the enzyme activities, in a way, that NaOH and AHP treatment significantly reduced CMCase and FP degrading enzyme. The effect of urea treatment showed an increase in the activity of MCCase and $\alpha$-glucosidase. But the supplementation of urea increased the activity of CMCase, FP degrading enzyme and $\alpha$-glucosidase. The CMCase, $\alpha$-amylase, $\alpha$-glucosidase activities were highest at 4hr whereas MCCase and FP degrading enzyme had maximum activities at 12 h post feeding Results suggested that MS might need longer time in the rumen for its effective degradation.

Immunomodulatory Effects of Propolis and Fermented-propolis in BALB/c Mice (프로폴리스 및 발효 프로폴리스의 섭취가 BALB/c mice의 면역활성에 미치는 영향)

  • Kim, Yoon-Hee;Kwon, Hyuck-Se;Kim, Dae-Hwan;Park, IL-Hwan;Park, Sang-Jae;Shin, Hyun-Kyung;Kim, Jin-Kyung
    • Korean Journal of Food Science and Technology
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    • v.40 no.5
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    • pp.574-579
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    • 2008
  • Propolis is the generic term for the resinous substance collected by honey bees from a variety of plant sources. In this study, we have assessed the immunomodulatory properties of propolis (P) and fermented-propolis (FP) in BALB/c mice. Mice were subjected to gavage once a day (for 14 days) with 50, 100, 200 mg/kg body weight P, FP, or vehicle. Lymphocytes were isolated from the spleen and mesenteric lymph nodes (MLN) and the immune cell proportions, proliferative activities, and cytokine production were evaluated. The P- and FP-administration induced similar, but differential, alterations in the percentage of immune cell populations and their biological functions, including cytokine production and NK cell cytotoxicity. The proportion of$ CD4^+$ and $CD8^+$ T cells in the spleen was increased slightly in the P- and FP-administered mice as compared to the vehicle-treated mice. In MLN, the percentage of $CD4^+$ T cells was increased significantly in the 200 mg/kg P-treated mice. The mice which were treated with P and FP evidenced significantly increased interferon-$\gamma$ and interleukin-4 production in concanavalin A-stimulated splenocytes, whereas the production of theses cytokines was not shown to be induced by P-treatment. In addition, NK cell activity was also increased dramatically by the administration of P and FP. Collectively, these findings showed that P and FP are wide-spectrum immunomodulators, which may modulate both innate and adaptive immune responses.

The Effect of Saturated Fatty Acids on Cellulose Digestion by the Rumen Anaerobic Fungus, Neocallimatix frontalis C5-1

  • Ha, J.K.;Lee, S.S.;Gao, Z.;Kim, C.-H.;Kim, S.W.;Ko, Jong Y.;Cheng, K.-J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.7
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    • pp.941-946
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    • 2001
  • The effects of various concentrations of saturated fatty acids (SFA; caprylic, capric and stearic acids) on the growth of the anaerobic fungus, Neocallimastix frontalis C5-1 isolated from the rumen of a Korean native goat were investigated. At higher concentrations of fatty acids (0.1%, w/v), the addition of SFA strongly decreased filter paper (FP) cellulose digestion and polysaccharide-degrading enzyme activity. The sensitivity of the rumen anaerobic fungus to the added fatty acids increased in the following order: caprylic ($C_{8:0}$)>capric($C_{10:0}$)>stearic($C_{18:0}$) acid, although stearic acid had no significant (p<0.05) inhibitory effects at any of the concentrations tested. However, the addition of SFA at lower concentrations (0.01 and 0.001% levels), did not inhibit FP cellulose degradation and enzyme activity. Furthermore, although these parameters were slightly stimulated by the addition of SFA, they were not statistically different from control values. This is the first report examining the effects of fatty acids on anaerobic gut fungi. We found that the lower levels of fatty acids used in this experiment were able to stimulate the growth and specific enzyme activities of rumen anaerobic fungi, whereas the higher levels of fatty acids were inhibitory with respect to fungal cellulolysis.

Effects of Single or Mixed Supplementation of Bacterial Phytase and Fungal Phytase on Laying Performance and Nutrient Digestibility (Bacterial 및 Fungal Phytase의 단일 및 혼합 급여가 산란계의 생산성과 영양소 이용에 미치는 영향)

  • Kang, H.K.;Park, S.Y.;Yu, D.J.;Kim, J.H.;Kang, G.H.;Na, J.C.;Kim, D.W.;Suh, O.S.;Lee, S.J.;Lee, W.J.;Kim, S.H.
    • Korean Journal of Poultry Science
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    • v.35 no.2
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    • pp.137-142
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    • 2008
  • This study was conducted to investigate the effect of single or mixed supplementation of bacterial and fungal phytase using 45-wk-old 450 Hy-Line Brown laying hens housed in individual cages for 12-wk period. The birds were reallocated to have similar egg productivity by examining the egg production for one wk before starting the experiment. Two sources of phytase, bacterial (BP) and fungal (FP), were used either in single or mixture to determine the effects of these phytase. Five dietary treatments consisted of control (BP 0, FP 0), T1 (BP 300, FP 0), T2 (BP 300, FP 300), T3 (BP 300, FP 3000), and T4 (BP 0, FP 3000). The DPU was used for phytase activity in this experiment. The nonphytate phosphorus (NPP) content of control was 0.30%, and those of phytase treatments were set to 60% of the Control. Experimental diets were fed ad libitum throughout the experimental period. The lighting schedule of 17L7D was employed. The egg production was not different between control and bacterial phytase treatments, but the T4 showed significantly low productivity compared to control (P<0.05). No difference was found in average egg weight among all treatments. The daily egg mass did not show any statistical differences among all treatments: however, it was significantly low in T4 compared to ther control during the latter half of the experiment (P<0.05). No significant difference was found among treatments in terms of feed intake, feed conversion and egg quality. The digestibilities of dry matter, crude protein, and fat digestibility were similar regardless of the treatments. No significant trends were detected in Ca and P availability. In conclusion, the BP level of 300 DPU contributed to achieve 40% reduction of recommended nonphytate phosphorus addition. The synergistic effect of bacterial and fungal phytase was not confirmed.

Production of Cellulase by Trichoderma reesei Rut C30 in Wheat Bran-containing Media

  • Yu, Xiao-Bin;Yun, Hyun-Shik;Koo, Yoon-Mo
    • Journal of Microbiology and Biotechnology
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    • v.8 no.3
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    • pp.208-213
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    • 1998
  • The effect of the addition of wheat bran to the growth medium on the production of cellulolytic enzymes of Trichoderma reesei Rut C30 was studied in batch culture using shake flasks. The activity of cellulase was enhanced by the addition of wheat bran to the cellulase production medium. $KH_2PO_4$-$K_2HPO_4$ buffer was used for pH control during cellulase production. As a result, high cellulase activities were obtained in shake flask culture; a CMC (carboxymethyl cellulose) activity of 125.78 U/ml was obtained from 2% Avicel- and 3% wheat bran-containing medium and an FP (filter paper) activity of 12.85U/ml was obtained from 1% Avicel- and 5% wheat bran-containing medium after 6 days of cultivation.

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The Measurement and Prediction of Flash Point for Binary Mixtures of Methanol, Ethanol, 2-Propanol and 1-Butanol at 101.3 kPa (Methanol, Ethanol, 2-Propanol 그리고 1-Butanol 이성분 혼합계에 대한 101.3 kPa에서의 인화점 측정 및 예측)

  • Oh, In Seok;In, Se Jin
    • Fire Science and Engineering
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    • v.29 no.5
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    • pp.1-6
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    • 2015
  • Flash point is one of the most important variables used to characterize fire and explosion hazard of liquids. The lower flash point data were measured for the binary systems {methanol + 1-butanol}, {ethanol + 1-butanol} and {2-propanol + 1-butanol} at 101.3 kPa. Experiments were performed according to the standard test method (ASTM D 3278) using a SETA closed cup flash point tester. The measured flash points were compared with the predicted values calculated using the following activity coefficient models: Wilson, Non-Random Two Liquid (NRTL), and UNIversal QUAsiChemical (UNIQUAC). The measured FP data agreed well with the predicted values of Raoult's law, Wilson, NRTL and UNIQUAC models. The average absolute deviation between the predicted and measured lower FP was less than 1.14 K.

Evaluation of Cranial Sacral Therapy (CST) Based Pillow on Sleep Induction Using the Electroencephalogram (EEG) (뇌파를 이용한 두개천골요법 기반 베개의 수면유도 효과 검증)

  • Kwon, Hyeok Chan;Phyo, Jung Bin;Park, Yong Gil;Lee, Hyun Ju;Tae, Ki Sik
    • Journal of Biomedical Engineering Research
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    • v.39 no.1
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    • pp.55-61
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    • 2018
  • The purpose of this study was to investigate the effect of a pillow simulated with cranial sacral therapy (CST) on sleep induction using electroencephalography (EEG). This study included 12 voluntary participants divided into experimental group (CST group) and control group (Non-CST group) to observe EEG changes. The position of the electrode for EEG measurement consists of 8 channels electrodes (Fp1, Fp2, F3, F4, T3, T4, P3 and P4). In this study, we measured the fall asleep time, change of brain activity and sleep wave ratio using EEG wave (${\delta}$, ${\theta}$, ${\alpha}$, ${\beta}$ and ${\gamma}$). As a result, the mean fall asleep time of the experimental group was shorter than that of the control group significantly (p < 0.001). Also in comparison with the control group, both the delta (d) and theta (q) wave corresponding to the slow waves showed a larger increase and the alpha (a) wave showed a larger decrease significantly. The slow waves of experimental group showed a higher rate of significant increase than the control group (p < 0.001). Therefore this study showed that pillow based on CST had an effective in improving sleep induction and quality.

Improved Production of Ligninase and Laccase by Phanerochaete chrysosporium and Ceriporiopsis subvermispora (Phanerochaete chrysosporium과 Ceriporiopsis subvermispora 균주(菌株)의 Ligninase 및 Laccase 생산최적조건에 관한 연구(硏究))

  • Kang, An-Seok;Cha, Dong-Yeul;Kim, Kyung-Soo;Hong, In-Pyo;Croan, Suki C.;Yu, Seung-Hun
    • The Korean Journal of Mycology
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    • v.22 no.3
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    • pp.254-259
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    • 1994
  • The ever increasing demand for energy and the shortage of resources all over the world have generated interest in recycling renewable sources such as lignocelluloses which otherwise would go to waste and cause environmental pollution. Lignin is the incrustation material for cellulose and hemicellulose, therefore, cellulose and hemicellulose are not easily degraded. Recycling lignocellulosic wastes as agricultural material are benefit to everybody and everything. In order to improve ligninase and laccase production of Phanerochaete chrysosporium, BKM-F-1767 and Ceriporiopsis subvermispora, FP 90031-SP, were compared. The ligninase activity of P. chrysosporium was maximum on day 4.5 of shaking culture at 150 rpm 2.5 cm in a back and forth cycle. The laccase activity of C. subvermispora was maximum on day 5.5 for 2% malt extract+0.1% yeast extract+0.1% Tween 20+6 mM Benzyl alcohol culture medium at stationary state.

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