• 제목/요약/키워드: FG-5

검색결과 226건 처리시간 0.022초

Effects of vitamin D supplementation on metabolic indices and hs-CRP levels in gestational diabetes mellitus patients: a randomized, double-blinded, placebo-controlled clinical trial

  • Yazdchi, Roya;Gargari, Bahram Pourghassem;Asghari-Jafarabadi, Mohammad;Sahhaf, Farnaz
    • Nutrition Research and Practice
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    • 제10권3호
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    • pp.328-335
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    • 2016
  • BACKGROUND/OBJECTIVES: Vitamin D plays an important role in the etiology of gestational diabetes mellitus (GDM). This study evaluated the effect of vitamin D supplementation on metabolic indices and hs-C-reactive protein (CRP) levels in GDM patients. SUBJECTS/METHODS: The study was a randomized, placebo-controlled, double-blinded clinical trial. Seventy-six pregnant women with GDM and gestational age between 24-28 weeks were assigned to receive four oral treatments consisting of 50,000 IU of vitamin $D_3$ (n = 38) or placebo (n = 38) once every 2 weeks for 2 months. Fasting blood glucose (FG), insulin, HbA1c, 25-hydroxyvitamin D, lipid profile, hs-CRP, and homeostasis model assessment-insulin resistance (HOMA-IR) were measured before and after treatment. Independent and paired t-tests were used to determine intra- and intergroup differences, respectively. ANCOVA was used to assess the effects of vitamin D supplementation on biochemical parameters. RESULTS: Compared with the placebo group, in the vitamin D group, the serum level of 25-hydroxyvitamin D increased (19.15 vs. -0.40 ng/ml; P < 0.01) and that of FG (-4.72 vs. 5.27 mg/dl; P = 0.01) as well as HbA1c (-0.18% vs. 0.17%; P = 0.02) decreased. Improvements in the lipid profiles were observed in the vitamin D group, but without statistical significance. Significant increases in concentrations of hs-CRP, FG, HbA1c, total cholesterol, and LDL cholesterol were observed in the placebo group. No significant change in fasting insulin and HOMA-IR was observed in either group. CONCLUSIONS: In GDM patients, vitamin D supplementation improved FG and HbA1c but had no significant effects on lipid profile or hs-CRP.

SWAT을 이용한 장기간 지하수 양수와 산림 성장이 수문에 미치는 영향 평가 (Assessment of long-term groundwater abstraction and forest growth impacts on watershed hydrology using SWAT)

  • 김원진;우소영;김세훈;김진욱;김성준
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2021년도 학술발표회
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    • pp.101-101
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    • 2021
  • 본 연구에서는 금강 유역(9,645.5 km2)을 대상으로 SWAT(Soil and Water Assessment Tool)을 이용하여 장기간 지하수 양수와 산림 성장이 수문에 미치는 영향을 평가하였다. 1976년부터 2015년까지 40년의 지하수 이용량(GU)과 산림 성장(FG) 자료를 10년 단위(1980s; 1976~1985, 1990s; 1986~1995, 2000s; 1996~2005, 2010s; 2006~2015)로 구축하고, SWAT 입력자료와 증발산량 매개변수로 사용하여 연대별 지하수 양수와 산림 생장을 반영하였다. 금강 유역 내 위치한 2개의 다목적댐과 3개의 다기능 보에서 관측된 일별 유량으로 2006년부터 2015까지 10년을 검·보정하여 모델의 적용성을 검증하였다. 5지점에 대한 검보정 결과, NSE는 0.76에서 0.79, R2는 0.78에서 0.81, RMSE는 0.55 mm/day에서 1.96 mm/day, PBIAS는 -5.48%에서 8.56%로 통계적으로 유의한 수준으로 분석되었다. 적용성을 검증한 SWAT에 각 연대에 맞는 GU와 FG 정보를 입력하여 수문을 모의하였으며, 두 요인이 물순환에 미치는 영향을 평가하기 위하여 기상조건은 2010s로 고정하였다. 모의결과, GU와 FG 변화가 주는 영향으로 유역 출구의 총유출량은 7.8%(60.7 mm/year) 감소하였으며, 1980s과 2010s에서 각각 775.0 mm/year, 714.3 mm/year의 값을 보였다. 물순환 분석 결과, 지표유출, 중간유출, 기저유출, 침투량, 토양수분은 감소하는 경향을 보였고, 증발산량과 지하수 충전량(GWR)은 증가하는 경향을 보였다. GU의 증가로 인한 지하수위의 지속적인 감소가 GWR이 증가하는 원인으로 판단하였으며, 강우 기간에 포장용수량 이상의 토양수가 빠르게 흘러 지하수 충전량을 증가시켰다고 추론하였다. 또한, 유황 곡선을 분석한 결과, 유량이 지하수 양수와 산림 생장에 영향을 받은 지역에서 시간 흐름에 따라 감소하였고, 저유량 구간에서 상대적으로 많이 감소하였다.

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Static stability and of symmetric and sigmoid functionally graded beam under variable axial load

  • Melaibari, Ammar;Khoshaim, Ahmed B.;Mohamed, Salwa A.;Eltaher, Mohamed A.
    • Steel and Composite Structures
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    • 제35권5호
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    • pp.671-685
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    • 2020
  • This manuscript presents impacts of gradation of material functions and axial load functions on critical buckling loads and mode shapes of functionally graded (FG) thin and thick beams by using higher order shear deformation theory, for the first time. Volume fractions of metal and ceramic materials are assumed to be distributed through a beam thickness by both sigmoid law and symmetric power functions. Ceramic-metal-ceramic (CMC) and metal-ceramic-metal (MCM) symmetric distributions are proposed relative to mid-plane of the beam structure. The axial compressive load is depicted by constant, linear, and parabolic continuous functions through the axial direction. The equilibrium governing equations are derived by using Hamilton's principles. Numerical differential quadrature method (DQM) is developed to discretize the spatial domain and covert the governing variable coefficients differential equations and boundary conditions to system of algebraic equations. Algebraic equations are formed as a generalized matrix eigenvalue problem, that will be solved to get eigenvalues (buckling loads) and eigenvectors (mode shapes). The proposed model is verified with respectable published work. Numerical results depict influences of gradation function, gradation parameter, axial load function, slenderness ratio and boundary conditions on critical buckling loads and mode-shapes of FG beam structure. It is found that gradation types have different effects on the critical buckling. The proposed model can be effective in analysis and design of structure beam element subject to distributed axial compressive load, such as, spacecraft, nuclear structure, and naval structure.

A simple quasi-3D HSDT for the dynamics analysis of FG thick plate on elastic foundation

  • Boukhlif, Zoulikha;Bouremana, Mohammed;Bourada, Fouad;Bousahla, Abdelmoumen Anis;Bourada, Mohamed;Tounsi, Abdelouahed;Al-Osta, Mohammed A.
    • Steel and Composite Structures
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    • 제31권5호
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    • pp.503-516
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    • 2019
  • This work presents a dynamic investigation of functionally graded (FG) plates resting on elastic foundation using a simple quasi-3D higher shear deformation theory (quasi-3D HSDT) in which the stretching effect is considered. The culmination of this theory is that in addition to taking into account the effect of thickness extension (${\varepsilon}_z{\neq}0$), the kinematic is defined with only 4 unknowns, which is even lower than the first order shear deformation theory (FSDT). The elastic foundation is included in the formulation using the Pasternak mathematical model. The governing equations are deduced through the Hamilton's principle. These equations are then solved via closed-type solutions of the Navier type. The fundamental frequencies are predicted by solving the eigenvalue problem. The degree of accuracy of present solutions can be shown by comparing it to the 3D solution and other closed-form solutions available in the literature.

Vibration analysis of damaged core laminated curved panels with functionally graded sheets and finite length

  • Zhao, Li-Cai;Chen, Shi-Shuenn;Xu, Yi-Peng;Tahouneh, Vahid
    • Steel and Composite Structures
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    • 제38권5호
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    • pp.477-496
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    • 2021
  • The main objective of this paper is to study vibration of sandwich open cylindrical panel with damaged core and FG face sheets based on three-dimensional theory of elasticity. The structures are made of a damaged isotropic core and two external face sheets. These skins are strengthened at the nanoscale level by randomly oriented Carbon nanotubes (CNTs) and are reinforced at the microscale stage by oriented straight fibers. These reinforcing phases are included in a polymer matrix and a three-phase approach based on the Eshelby-Mori-Tanaka scheme and on the Halpin-Tsai approach, which is developed to compute the overall mechanical properties of the composite material. Three complicated equations of motion for the panel under consideration are semi-analytically solved by using 2-D differential quadrature method. Several parametric analyses are carried out to investigate the mechanical behavior of these multi-layered structures depending on the damage features, through-the-thickness distribution and boundary conditions. It is seen that for the large amount of power-law index "P", increasing this parameter does not have significant effect on the non-dimensional natural frequency parameters of the FG sandwich curved panel. Results indicate that by increasing the value of isotropic damage parameter "D" up to the unity (fully damaged core) the frequency would tend to become zero. One can dictate the fiber variation profile through the radial direction of the sandwich panel via the amount of "P", "b" and "c" parameters. It should be noticed that with increase of volume fraction of fibers, the frequency parameter of the panels does not increase necessarily, so by considering suitable amounts of power-law index "P" and the parameters "b" and "c", one can get dynamic characteristics similar or better than the isotropic limit case for laminated FG curved panels.

Mechanical behaviour analysis of FGM plates on elastic foundation using a new exponential-trigonometric HSDT

  • Fatima Z. Zaoui;Djamel Ouinas;Abdelouahed Tounsi;Belkacem Achour;Jaime A. Vina Olay;Tayyab A. Butt
    • Steel and Composite Structures
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    • 제47권5호
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    • pp.551-568
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    • 2023
  • In this research, a new two-dimensional (2D) and quasi three-dimensional (quasi-3D) higher order shear deformation theory is devised to address the bending problem of functionally graded plates resting on an elastic foundation. The displacement field of the suggested theories takes into account a parabolic transverse shear deformation shape function and satisfies shear stress free boundary conditions on the plate surfaces. It is expressed as a combination of trigonometric and exponential shear shape functions. The Pasternak mathematical model is considered for the elastic foundation. The material properties vary constantly across the FG plate thickness using different distributions as power-law, exponential and Mori-Tanaka model. By using the virtual works principle and Navier's technique, the governing equations of FG plates exposed to sinusoidal and evenly distributed loads are developed. The effects of material composition, geometrical parameters, stretching effect and foundation parameters on deflection, axial displacements and stresses are discussed in detail in this work. The obtained results are compared with those reported in earlier works to show the precision and simplicity of the current formulations. A very good agreement is found between the predicted results and the available solutions of other higher order theories. Future mechanical analyses of three-dimensionally FG plate structures can use the study's findings as benchmarks.

Investigation of the mechanical behavior of functionally graded sandwich thick beams

  • Mouaici, Fethi;Bouadi, Abed;Bendaida, Mohamed;Draiche, Kada;Bousahla, Abdelmoumen Anis;Bourada, Fouad;Tounsi, Abdelouahed;Ghazwani, Mofareh Hassan;Alnujaie, Ali
    • Steel and Composite Structures
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    • 제44권5호
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    • pp.721-740
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    • 2022
  • In this paper, an accurate kinematic model has been developed to study the mechanical response of functionally graded (FG) sandwich beams, mainly covering the bending, buckling and free vibration problems. The studied structure with homogeneous hardcore and softcore is considered to be simply supported in the edges. The present model uses a new refined shear deformation beam theory (RSDBT) in which the displacement field is improved over the other existing high-order shear deformation beam theories (HSDBTs). The present model provides good accuracy and considers a nonlinear transverse shear deformation shape function, since it is constructed with only two unknown variables as the Euler-Bernoulli beam theory but complies with the shear stress-free boundary conditions on the upper and lower surfaces of the beam without employing shear correction factors. The sandwich beams are composed of two FG skins and a homogeneous core wherein the material properties of the skins are assumed to vary gradually and continuously in the thickness direction according to the power-law distribution of volume fraction of the constituents. The governing equations are drawn by implementing Hamilton's principle and solved by means of the Navier's technique. Numerical computations in the non-dimensional terms of transverse displacement, stresses, critical buckling load and natural frequencies obtained by using the proposed model are compared with those predicted by other beam theories to confirm the performance of the proposed theory and to verify the accuracy of the kinematic model.

Static analysis of nonlinear FG-CNT reinforced nano-composite beam resting on Winkler/Pasternak foundation

  • Mostefa Sekkak;Rachid Zerrouki;Mohamed Zidour;Abdelouahed Tounsi;Mohamed Bourada;Mahmoud M Selim;Hosam A. Saad
    • Advances in nano research
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    • 제16권5호
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    • pp.509-519
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    • 2024
  • In this study, the static analysis of carbon nanotube-reinforced composites (CNTRC) beams resting on a Winkler-Pasternak elastic foundation is presented. The developed theories account for higher-order variation of transverse shear strain through the depth of the beam and satisfy the stress-free boundary conditions on the top and bottom surfaces of the beam. To study the effect of carbon nanotubes distribution in functionally graded (FG-CNT), we introduce in the equation of CNT volume fraction a new exponent equation. The SWCNTs are assumed to be aligned and distributed in the polymeric matrix with different patterns of reinforcement. The rule of mixture is used to describe the material properties of the CNTRC beams. The governing equations were derived by employing Hamilton's principle. The models presented in this work are numerically provided to verify the accuracy of the present theory. The analytical solutions are presented, and the obtained results are compared with the existing solutions to verify the validity of the developed theories. Many parameters are investigated, such as the Pasternak shear modulus parameter, the Winkler modulus parameter, the volume fraction, and the order of the exponent in the volume fraction equation. New results obtained from bending and stresses are presented and discussed in detail. From the obtained results, it became clear the influence of the exponential CNTs distribution and Winkler-Pasternak model improved the mechanical properties of the CNTRC beams.

한반도지역에서의 절대 중력관측 (The Absolute Gravity Measurements in Korean Peninsula)

  • 조진동;김경수;안기덕;우삼용
    • 자원환경지질
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    • 제36권5호
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    • pp.387-389
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    • 2003
  • 한반도지역에서 중력 기준점 설치, 기 설치된 중력 기준점의 중력 값들의 정밀도 향상 및 중력가속도 값을 얻기 위하여, 표준연구원(KRISS)은 한 중 공동으로 1996년 10월8일∼11월8일까지, 국립지리원(NGI)은 한$.$일공동으로 1999년 12월10∼16일까지 각각 대전과 수원에서 절대 중력계(Laser Interferometry Absolute Gravimeter type NIM-II와 FG5 Absolute Gravity meter(#203))를 사용하여 절대중력관측을 수행하였다. 표준연구원과 국립지리원이 관측한 절대 중력 값은 각각 979,829.609${\pm}$006 mGal(대전), 979,918.775${\pm}$0.0001 mGal(수원)이다. 앞으로 한반도에서 지구과학분야 활성화를 위해서 더 많은 절대중력 기준점의 확보가 필요하다고 사려된다.

수퍼커패시터 전극을 위한 폴리아닐린/TiO2 복합체의 제조 및 전기화학적 성질 (Preparation and Electrochemical Properties of PANI/TiO2 Composites for Supercapacitor Electrodes)

  • 박수근;김광만;이영기;정용주;김석
    • Korean Chemical Engineering Research
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    • 제50권1호
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    • pp.50-54
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    • 2012
  • 본 연구는 커패시터 전극 응용을 위한 복합체 전극에 관련된 것으로 PANI와 PANI/$TiO_2$로 구성된 수퍼커패시터 전극을 제조하여 cyclic voltammetry(CV)를 이용하여 6 M KOH 수용액에서 축전량(capacitance) 특성을 조사하였다. PANI/$TiO_2$ 복합체는 간단한 in-situ 방법을 통해 다양한 비율로 합성되었다. PANI/$TiO_2$ 복합체의 형태학(morphology)적 특징을 파악하기 위해서 주사전자현미경(SEM)과 투과전자현미경(TEM)을 통해 분석하였고, X선 회절 분석기(XRD)를 이용하여 복합체의 결정화도와 담지된 $TiO_2$의 입자크기를 확인하였다. 전기화학적 시험 결과, 아닐린 대비 $TiO_2$의 주입량이 10 wt%일 때 가장 우수한 축전량(626 $Fg^{-1}$)을 나타냈고 높은 주사속도인 100 $mVs^{-1}$에서 286 $Fg^{-1}$의 비축전량을 나타내었다. 이는 폴리아닐린(PANI) 매트릭스(matrix)에 균일하게 담지된 $TiO_2$(~6.5 nm)가 효과적인 연결 구조를 형성하여 전하이동현상이 증가하고, 축전이 가능한 반응면적이 증가한 것과 관련있다고 판단된다.