• Proceedings of the KIPE Conference
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• 2015.11a
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• pp.119-120
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• 2015

ITER 한국사업단은 AC/DC Converter 최종설계검토(FDR)를 2014년 4월에 끝내고, 제작에 관련된 준비사항 점검인 MRR (Manufacturing Readiness Review)를 2014년 10월에 수행하였다. 1차 제작공정인 CCU/L 컨버터와 관련 I&C System은 2014년 11월부터 제작에 착수하여 곧 FAT(Factory Acceptance Test)를 앞두고 있다. 이 시점에서 중요한 것은 FAT를 앞둔 제작된 기기가 ITER의 설계요건을 충분히 만족하는지에 대한 검증을 하는 것이다. 본 논문은 초전도자석 및 컨버터의 이상상태 또는 고장 시에 장치를 보호하는 중요한 Plant Interlock System(PIS)이 ITER의 설계요건을 충실히 반영하였는지 확인하기 위한 요건추적매트릭스(RTM) 기법을 소개하고, Interlock System의 중요기능인 사고 시 초전도 코일에 충전된 에너지를 급속 방전하기 위한 장치인 DLIB와의 연계기능에 적용한 예를 보이고자 한다.

• Microbiology and Biotechnology Letters
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• v.47 no.3
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• pp.423-433
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• 2019

Midgut microbiota is known to play a fundamental role in the biology and physiology of the agricultural pest, Spodoptera litura. This study reports the difference in the larval midgut microbiota of field-caught and laboratory-reared populations of S. litura by performing 16S rDNA amplicon pyrosequencing. Field populations for the study were collected from castor crops, whereas laboratory-reared larvae were fed on a regular chickpea based diet. In total, 23 bacterial phylotypes were observed from both laboratory-reared and field-caught caterpillars. Fisher's exact test with Storey's FDR multiple test correction demonstrated that bacterial genus, Clostridium was significantly abundant (p < 0.05) in field-caught larvae of S. litura as compared to that in the laboratory-reared larvae. Similarly, bacterial genera, such as Bradyrhizobium, Burkholderia, and Fibrisoma were identified (p < 0.05) predominantly in the laboratory-reared population. The Bray-Curtis dissimilarity matrix depicted a value of 0.986, which exhibited the maximum deviation between the midgut microbiota of the laboratory-reared and field-caught populations. No significant yeast diversity was seen in the laboratory-reared caterpillars. However, two yeast strains, namely Candida rugosa and Cyberlindnera fabianii were identified by PCR amplification and molecular cloning of the internal transcribed space region in the field-caught caterpillars. These results emphasize the differential colonization of gut residents based on environmental factors and diet.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.1
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• pp.751-758
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• 2021

This research is conducted to measure the efficiency level of Islamic banking in Indonesia and also to analyze the factors that can affect its efficiency level. This research used a purposive sampling technique to determine the sample size that will be used, with criteria that the bank has been operating since 2010 and consistently published its financial reports during the research period from 2011 until 2019; therefore, the total sample obtained was 11 samples. Analysis for efficiency level is done by using linear programming Stochastic Frontier Analysis (SFA), with test tool in the form of Frontier 4.1 and Eviews9 to find out what factors that affect efficiency. Efficiency test is done by involving input and output, while influence test used bank-specific variables comprising bank size, bank financial ratio, and macro-economy variable. Research result shows that there are only two banks that are almost close to being fully efficient firms, but the result still does not indicate that Islamic bank works efficiently. Results of the influence test show that factors affecting Islamic banking efficiency in Indonesia are bank size, Capital Adequacy Ratio (CAR), Non-Performing Finance (NPF), and Financing to Deposit Ratio (FDR), while other factors are not influential over the study period.

• Journal of Radiation Industry
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• v.17 no.4
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• pp.359-367
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• 2023

In this study, the function and purpose of the disposal cover, which is an engineering barrier installed to isolate the disposal vault of the near-surface disposal facility for radioactive waste from natural/man-made intrusion, and the design details of the demonstration facility for performance verification were described. The Demonstration facility was designed in a partially divided form to secure the efficiency of measurement while being the same as the actual size of the surface disposal facility to be built in the Intermediate & low-level radioactive waste disposal site of the Korea Radioactive Waste Agency (KORAD). The instruments used for measurement consist of a multi-point thermometer, FDR (Frequency Domain Reflectometry) sensor, inclinometer, acoustic sensor, flow meter, and meteorological observer. It is used as input data for the monitoring system. The 3D monitoring system was composed of 5 layers using the e-government standard framework, and was developed based on 4 components: screen, control module, service module, and DBIO(DataBase Input Output) module, and connected them to system operation. The monitoring system can provide real-time information on physical changes in the demonstration facility through the collection, analysis, storage, and visualization processes.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2017.04a
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• pp.132-132
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• 2017

고품질 농산물을 대량 생산하기 위한 가장 중요한 것은 적절한 관개관리이다. 생육시기별 작물 재배에 있어서 꼭 필요한 만큼의 물을 필요한 때에 준다면, 농업용수를 절약할 수 있을 뿐만 아니라, 작물의 한발 및 습해에 따른 피해를 최소화 할 수 있을 것이다. 기존의 토양 및 증발산량 기반의 자동 물관리 기술의 경우 직접적으로 작물의 상태변화를 실시간으로 확인할 수 없으며, 측정오차가 크고 작물수량이 많을 경우 측정시간 및 소요비용이 크다는 단점이 있다. 이를 극복하기 위해 최근 작물의 수분 스트레스를 비파괴적으로 측정하여 관개계획에 활용하는 연구가 해외에서 활발히 이루어지고 있다. 본 연구에서는 열영상 기술을 활용한 적정 관개계획 수립과 관련된 국내외 연구 사례를 소개하고, 오이를 대상으로 토양수분함량 변화에 따른 엽온 변화를 측정하고, 실시간으로 작물의 수분스트레스 여부를 분석하기 위한 예비실험을 실시하였다. 엽온 측정을 위해 적외선 센서(CT-300-232, DiWell, Korea)를 사용하였으며, 관개조건에 따른 엽온 및 FDR센서를 이용하여 토양수분변화를 모니터링 하였다. 세 가지 토양수분조건, 즉 200% $ET_c$(과다관개), 100% $ET_c$(적정관개), 30% $ET_c$(과소관개),을 시험구에 조성하고, 각각의 처리구에 따른 엽온변화를 측정하였다. 동일한 대기온도하에서 엽온의 변화를 살펴본 결과, 과소관개한 시험구에서의 엽온변화 폭이 가장 컸으며, 적정관개의 엽온 변화폭이 가장 작게 나타났다. 이는 물관리 조건에 따라 많이 줘도, 적게 줘도 스트레스 요인으로 작용함을 확인할 수 있었다. 향후 연구에서는 실시간 엽온자료와 더불어 기상자료를 활용하여 작물 수분스트레스 지수(Crop Water Stress Index, CWSI)을 산정하고, 이를 관개시설 운영 및 제어에 활용하기 위한 모듈 개발을 수행할 계획이다.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.608-612
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• 2009

본 연구에서는 하수재이용에 따른 토양에서의 염분변화를 추정하기 위하여 SWAP(Soil-Water-Atmosphere-Plant) 모형을 선정하여 경기도 화성시 수원환경사업소 인근에 위치한 병점지구를 대상으로 모형의 적용성을 분석하였다. 실험에 사용한 관개용수는 1) 지하수(TR#1), 2) 하수처리장 방류수+여과+UV (TR#3)로 분류하여 실험에 사용하였다. 영농기간 동안 논으로 유입되는 총 유입수는 $1,724.2^{\sim}1,733.7$ mm 범위였으며, 이 중 약 64%가 강우에 의해 공급되었고, 나머지는 관개에 의하여 유입되었다. 유입관개수의 EC는 지하수 관개수인 TR#1이 다른 처리구에 비해 작았고, TR#3의 경우 $0.442{\sim}0.698$ dS/cm의 범위를 보였다. 모형의 보정과 검정을 위해서 대상지구에 FDR(Frequency Domain Reflection)을 설치하여 토양수분함유량과 염분농도를 토심에 따라 일단위로 모니터링 하였다. 토양함수량의 보정기간 중 토심별(50, 100, 140 cm) RMSE는 TR#1에서 $0.001^{\sim}0.002$ $cm^3cm^{-3}$, TR#3에서 $0.002^{\sim}0.006$ $cm^3cm^{-3}$으로 나타났으며, 검정기간 중 토심별 RMSE는 TR#1에서 $0.003^{\sim}0.064$ $cm^3cm^{-3}$, TR#3에서 0.001$cm^3cm^{-3}$로 나타났다. 토양염분의 보정기간 중 토심별 RMSE는 TR#1에서 $0.001^{\sim}0.023{\times}10^{-3}$ dS $m^{-1}$, TR#3에서 $0.028^{\sim}0.045{\times}10^{-3}$ dS$m^{-1}$로 나타났으며, 검정기간의 토심별 RMSE는 TR#1에서 $0.018^{\sim}0.037{\times}10^{-3}$ dS$m^{-1}$, TR#3에서 $0.004^{\sim}0.014{\times}10^{-3}$ dS$m^{-1}$로 적용성이 있는 것으로 나타났다.

• Genomics & Informatics
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• v.5 no.4
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• pp.143-151
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• 2007

To understand the mechanism of transcriptional regulation, it is essential to detect promoters and regulatory elements. Various kinds of methods have been introduced to improve the prediction accuracy of regulatory elements. Since there are few experimentally validated regulatory elements, previous studies have used criteria based solely on the level of scores over background sequences. However, selecting the detection criteria for different prediction methods is not feasible. Here, we studied the calibration of thresholds to improve regulatory element prediction. We predicted a regulatory element using MATCH, which is a powerful tool for transcription factor binding site (TFBS) detection. To increase the prediction accuracy, we used a regulatory potential (RP) score measuring the similarity of patterns in alignments to those in known regulatory regions. Next, we calibrated the thresholds to find relevant scores, increasing the true positives while decreasing possible false positives. By applying various thresholds, we compared predicted regulatory elements with validated regulatory elements from the Open Regulatory Annotation (ORegAnno) database. The predicted regulators by the selected threshold were validated through enrichment analysis of muscle-specific gene sets from the Tissue-Specific Transcripts and Genes (T-STAG) database. We found 14 known muscle-specific regulators with a less than a 5% false discovery rate (FDR) in a single TFBS analysis, as well as known transcription factor combinations in our combinatorial TFBS analysis.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.2
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• pp.103-113
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• 2012

본 연구에서는 하수재이용에 따른 논에서의 토양염분 변화를 추정하기 위하여 경기도 화성시 수원환경사업소 인근에 위치한 병점지구를 대상으로 수문순환과 작물성장과의 관계를 고려한 SWAP (Soil-Water-Atmosphere-Plant) 모형을 이용하여 평가하였다. 실험에 사용한 관개용수는 지하수 (TR#1), 하수처리장 방류수+여과+UV (TR#3)로 분류하여 모형에 사용하였다. 유입관개수의 EC (Electrical Conductivity)는 지하수 관개수인 TR#1이 다른 처리구에 비해 작았고, TR#3의 경우 0.442~0.698 dS $m^{-1}$의 범위를 보였다. 모형의 보정과 검정을 위해서 대상지구에 FDR (Frequency Domain Reflection)을 설치하여 토양수분함유량과 염분농도를 토심에 따라 일단위로 모니터링 하였다. 토심 (50, 100, 140 cm)에 따른 토양함수량의 RMSE는 검정기간 중 TR#1에서 0.003~0.064 $cm^3\;cm^{-3}$, TR#3에서 0.001 $cm^3\;cm^{-3}$ 범위를 보여 주었고, 토양염분의 보정기간 중 토심별 RMSE는 TR#1에서 0.018~0.037 dS $m^{-1}$, TR#3에서 0.004~0.014 dS $m^{-1}$ 범위를 보여 적용성이 있는 것으로 나타났다. 토양내의 염분수지 분석 결과, 토양에서의 염분저장량이 (-)로 나타나 토양내로 침출되는 것으로 나타났으며, WMRI (Water Management Response Indicators)을 이용한 분석 결과, 높은 침투능으로 인하여 토양에서의 염분 집적 영향은 낮은 것으로 평가되었다.

• Molecular & Cellular Toxicology
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• v.2 no.4
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• pp.273-278
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• 2006

95 squamous cell lung carcinoma samples (normal tissue: 40 samples, tumor: 55 samples) were analyzed with 8 K cDNA microarray. 1-way ANOVA test was employed to select differentially expressed genes in tumor with FDR<0.01. Among the selected 1,655 genes, final 212 genes were chosen according to the expression fold change and used for following analysis. The expression of up-regulated 64 genes was verified with Reverse Transcription PCR and 10 genes were identified as candidates for SCC markers. In our opinion, those candidates can be exploited as diagnostic or therapeutic purposes. Gene Ontology (GO) based analysis was performed using those 212 genes, and following categories were revealed as significant biological processes: Immune response (GO: 0006955), antigen processing (GO: 0030333), inflammatory response (GO: 0006954), Cell adhesion (GO: 0007155), and Epidermis differentiation (GO: 0008544). Gene set enrichment analysis (GSEA) also carried out on overall gene expression profile with 522 functional gene sets. Glycolysis, cell cycle, K-ras and amino acid biosynthesis related gene sets were most distinguished. These results are consistent with the known characteristics of SCC and may be interconnected to rapid cell proliferation. However, the unexpected results from ERK activation in squamous cell carcinoma gripped our attention, and further studies are under progress.

• Genomics & Informatics
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• v.4 no.4
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• pp.161-166
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• 2006

The establishment of DNA microarray technology has enabled high-throughput analysis and molecular profiling of various types of cancers. By using the gene expression data from microarray analysis we are able to investigate diagnostic applications at the molecular level. The most important step in the application of microarray technology to cancer diagnostics is the selection of specific markers from gene expression profiles. In order to select markers of Immortalization and transformation we used c-myc and $H-ras^{V12}$ oncogene-transfected NIH3T3 cells as our model system. We have identified 8751 differentially expressed genes in the immortalization/transformation model by multivariate permutation F-test (95% confidence, FDR<0.01). Using the support vector machine algorithm, we selected 13 discriminative genes which could be used to predict immortalization and transformation with perfect accuracy. We assayed $H-ras^{V12}$-transfected 'transformed' cells to validate our immortalization/transformation dassification system. The selected molecular markers generated valuable additional information for tumor diagnosis, prognosis and therapy development.