• Title/Summary/Keyword: FD & C Yellow No.5

Search Result 3, Processing Time 0.021 seconds

Effects of Excipients on Colour Fading of FD & C Yellow No. 5 and FD & C Red No. 2 by Use Tintometer (Tintometer를 이용한 FD & C Yellow No. 5와 FD & C Red No.2의 퇴색에 미치는 부형제의 영향에 관한 연구)

  • Kim, Jung-Woo
    • Journal of Pharmaceutical Investigation
    • /
    • v.5 no.2
    • /
    • pp.57-62
    • /
    • 1975
  • It was many differances to evaluate of the effect of excipients on colour fading in FD & C Yellow No.5 by use Tintometer and nearly is not effective in FD & C Red No. 2. When we observed colour fading in suger coating formulations by tintometer, FD & C Red No.2 was appeared to follow zero order reaction and FD & C Yellow No. 5 was not follow zero order reaction or first order reaction. Also, we could know the tendency of colour fading by visible spectrum, but it was net suitable method for this experiment more than by tintometer. The relative colour fading effect of the surfactants(Polysorbate) was as follows: Tween 60> Tween 80> Tween 20. In addition to, Benzalkonium chloride was reacted with FD & C Yellow No.5, so the stronger colour was appeared. On the other hand, the weaker colour was appeared in FD & C Red No.2. While, the sunscreening agents was not almost effective in colour fading of FD & Yellow No. 5 and FD & C Red No. 2.

  • PDF

The Effects of Food Azo Dyes on the Hepatic Microsomal Mixed Function Oxidase System in Rats (식용 Azo색소가 Hepatic Microsomal Mixed Function Oxidase System에 미치는 영향)

  • 윤혜정;김백화
    • YAKHAK HOEJI
    • /
    • v.31 no.6
    • /
    • pp.361-369
    • /
    • 1987
  • The four azo dyes such as Amaranth (FD & C Red No. 2), Tartrazine (FD & C Yellow No. 4), sunset Yellow (FD & C Yellow No. 5) and Allura red (FD & C Red No. 40) are currently employed as a food additives in Korea. In this study, the effects of these azo dyes on the hepatic microsomal mixed function oxidase systems in Rats. (i.e., Cyt. P-450, Cyt. b$_5$, NADPH cyt. c-reductase and azo reductase) were investigated. Furthermore, to determine the relationship among the electron transport systems, each level of azo reductase, Cyt. P-450 and NADPH cyt. c-reductase was measured upon the administration of phenobarbital (known as an inducer of Cyt. P-450), 3-methylcholanthrene (Known as an inducer of Cyt. P-448), CoCl$_2$ (inhibitor on Cyt. P-450) or $CCl_4$ (inhibitor on Cyt. P-450). The results of these studies are as follows; (1) The levels of Cyt. P-450 and Cyt. b$_5$ were decreased upon the administration of these azo dyes. (2) When the level of Cyt. P-450 was decreased, the azo reductase activity was also decreased. (3) These azo dyes did not show any significant effect on the level of NADPH cyt. c-reductase. (4) The administration of 3-methylcholanthrene resulted in the elevation of azo reductase activity. The 3-methylcholanthrene may be responsible for the induction of CO-insensitive electron transport system.

  • PDF

Adsorption Charateristics of Tartrazine by Activated Carbon (활성탄에 의한 Tartrazine의 흡착 특성)

  • Yoon, Sung Wook;Lee, Jong-Jib
    • Journal of Korean Society on Water Environment
    • /
    • v.25 no.4
    • /
    • pp.568-572
    • /
    • 2009
  • The adsorption characteristics of tartrazine by granular activated carbon were experimentaly investigated in the batch adsorber and the packed column. The adsorptivity of activated carbon for tartrazine was largely improved by pH control, and 98 percent of initial concentration could be removed at pH 3. It was estabilished that the adsorption equilibrium of tartrazine on granular activated carbon was sucessfully fitted by Freundlich isotherm equation in the concentration range from 50 mg/L to 1,000 mg/L. The characteristics of breakthrough curve of activated carbon packed column, which depend on the design variables such as initial concentration, bed height, and flow rate, were studied.