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Factors affecting pregnancy rates following transfer of bovine embryos derived from in vitro fertilization of oocytes matured in vitro (체외수정란 이식시 수태율에 미치는 요인에 관한 연구)

  • Kim, Sung-ki;Roh, Sang-ho;Lee, Eun-song;Lee, Byeong-chun;Hwang, Woo-suk
    • Korean Journal of Veterinary Research
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    • v.36 no.4
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    • pp.919-927
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    • 1996
  • In the last few years, methods for in vitro culture of early embryo stages from oocytes matured and fertilized in vitro using suitable cell culture systems have been established. But the factors affecting pregnancy rates following transfer of bovine embryos produced in vitro were not evaluated enough. So this study was performed to investigate the effects of quality and stage of embryos, parity and Corpus Luteum quality of recipients on pregnancy rates following non-surgical transfer of bovine embryos produced in vitro. Oocytes aspirated from small antral follicles of ovaries obtained at a local slaughter house were matured, fertilized with frozen-thawed semen and co-cultured for 6-7 days by utilizing co-culture system with bovine oviduct epithelial cell in vitro. After co-culture, embryos were transfered to recipients on day 7 (estrus=day 0). Recipients were monitored by ultrasonic scanning method or observation for estrus and rectal palpation after 50 days from transfer. The results of this study are follows. 1. Of the 70 recipients, 70%(49 of 70) had not showed estrus sign between day 0 and day 50, but 22.9%(16 of 70) was diagnosed not pregnant. Therefore the overall pregnancy rate of this study was 47.1%(33 of 70). 2. The pregnancy rate of recipients transfered with excellent(66.7%) and good(54.5%) embryos were higher than that of recipients transfered with fair embryos(15.8%) (p<0.05). 3. The pregnancy rate of recipients transfered with morula, compacted morula, blastocyst and expanded blastocysts were 46.2, 55.0, 62.5 and 50.0%, respectively. 4. The pregnancy rates of recipients transfered to heifer and cow were 54.5 and 55.2%, respectively. 5. The pregnancy rates of recipients with CL score I, II(66.7, 63.6%) were higher than those of recipients with CL score III (10%), (p<0.05). Success of transfer of embryos produced in vitro depends on many variables. The important factors identified in this study were the quality of embryos and the CL score of recipient animals after non-surgical transfer of embryos matured, fertilized and cultured in vitro.

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Usefulness of Comorbidity Indices in Operative Gastric Cancer Cases (위암 수술 환자의 건강결과 측정을 위한 동반상병 측정도구의 유용성 연구)

  • Hwang, Se-Min;Yoon, Seok-Jun;Ahn, Hyeong-Sik;An, Hyong-Gin;Kim, Sang-Hoo;Kyeong, Min-Ho;Lee, Eun-Kyoung
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.1
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    • pp.49-58
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    • 2009
  • Objectives : The purpose of the current study was to evaluate the usefulness of the following four comorbidity indices in gastric cancer patients who underwent surgery: Charlson Comorbidity Index(CCI), Cumulative Illness rating scale(CIRS), Index of Co-existent Disease(ICED), and Kaplan-Feinstein Scale(KFS). Methods : The study subjects were 614 adults who underwent surgery for gastric cancer at K hospital between 2005 and 2007. We examined the test-retest and inter-rater reliability of 4 comorbidity indices for 50 patients. Reliability was evaluated with Spearman rho coefficients for CCI and CIRS, while Kappa values were used for the ICED and KFS indices. Logistic regression was used to determine how these comorbidity indices affected unplanned readmission and death. Multiple regression was used for determining if the comorbidity indices affected length of stay and hospital costs. Results : The test-retest reliability of CCI and CIRS was substantial(Spearman rho=0.746 and 0.775, respectively), while for ICED and KFS was moderate(Kappa=0.476 and 0.504, respectively). The inter-rater reliability of the CCI, CIRS, and ICED was moderate(Spearman rho=0.580 and 0.668, and Kappa=0.433, respectively), but for KFS was fair(Kappa=0.383). According to the results from logistic regression, unplanned readmissions and deaths were not significantly different between the comorbidity index scores. But, according to the results from multiple linear regression, the CIRS group showed a significantly increased length of hospital stay(p<0.01). Additionally, CCI showed a significant association with increased hospital costs (p<0.01). Conclusions : This study suggests that the CCI index may be useful in the estimation of comorbidities associated with hospital costs, while the CIRS index may be useful where estimatation of comorbiditie associated with the length of hospital stay are concerned.

Congestion Control based on Genetic Algorithm in Wireless Sensor Network (무선 센서 네트워크에서 유전자 알고리즘 기반의 혼잡 제어)

  • Park, Chong-Myung;Lee, Joa-Hyoung;Jung, In-Bum
    • Journal of KIISE:Information Networking
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    • v.36 no.5
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    • pp.413-424
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    • 2009
  • Wireless sensor network is based on an event driven system. Sensor nodes collect the events in surrounding environment and the sensing data are relayed into a sink node. In particular, when events are detected, the data sensing periods are likely to be shorter to get the more correct information. However, this operation causes the traffic congestion on the sensor nodes located in a routing path. Since the traffic congestion generates the data queue overflows in sensor nodes, the important information about events could be missed. In addition, since the battery energy of sensor nodes exhausts quickly for treating the traffic congestion, the entire lifetime of wireless sensor networks would be abbreviated. In this paper, a new congestion control method is proposed on the basis of genetic algorithm. To apply genetic algorithm, the data traffic rate of each sensor node is utilized as a chromosome structure. The fitness function of genetic algorithm is designed from both the average and the standard deviation of the traffic rates of sensor nodes. Based on dominant gene sets, the proposed method selects the optimal data forwarding sensor nodes for relieving the traffic congestion. In experiments, when compared with other methods to handle the traffic congestion, the proposed method shows the efficient data transmissions due to much less queue overflows and supports the fair data transmission between all sensor nodes as possible. This result not only enhances the reliability of data transmission but also distributes the energy consumptions across the network. It contributes directly to the extension of total lifetime of wireless sensor networks.

How can the development of neighbourhood renewal strategies in Malaysia be informed by best practice and transferable lessons from developed countries (선진국 도시재생 사례비교를 통한 말레이시아 주거재생 전략의 모색)

  • Tin, Wan Jiun;Lee, Seok-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.4
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    • pp.469-486
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    • 2017
  • Economy-based urban redevelopment is the main priority in Malaysia, but has resulted in social problems such as gentrification, loss of heritage and identity, inequity, etc. Hence, it is crucial for the government to seek other alternatives rather than being solely reliant on urban redevelopment. Neighborhood renewal is a strategy involving the integration of redevelopment, rehabilitation, revitalization and preservation that aims to improve deprived areas using a more holistic approach. The aim of this paper is to review the neighborhood renewal policies in developed countries and to identify those elements that can be adopted in Malaysia. This study is conducted via a literature review. It was found that neighborhood renewal which integrates people-based, place-based and system-based policies highlights the importance of diversity, thereby aiming for resource optimization, community engagement and urban governance with the focal point of the fair, equity and systematic provision of resources. This paper concluded that neighborhood renewal in Malaysia should be initiated by locals with an emphasis on real local participation and a sustainable funding system. The government and local authorities should be observers rather than implementers.

Multi-Level Anterior Interbody Fusion with Internal Fixation in Cervical Spine (다분절 경추 유합 및 내고정 수술결과)

  • Jeon, Woo-Youl;Bae, Jang-Ho;Jung, Byoung-Woo;Kim, Seong-Ho;Kim, Oh-Lyong;Choi, Byung-Yon;Cho, Soo-Ho
    • Journal of Korean Neurosurgical Society
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    • v.30 no.sup1
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    • pp.55-60
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    • 2001
  • Objective : The purpose of the present study was to examine neurologic changes, fusion rate and degree of kyphosis from the surgical results of those patients who underwent multi-level anterior interbody fusion and internal fixation. Methods : Among 63 cases of the patients who received multi-level anterior interbody fusion and internal fixation in 5 years between 1995 to 1999 at the neurosurgery department, we performed a retrospective study in 52 cases that could be followed up with dynamic view imaging ; the results were compared and analyzed. The analysis was based on the results of history taking, physical findings and radiologic findings, and Odom criteria were used to classify those cases with neurologic changes. Results : Among those 52 cases in whom the follow-up was possible for at least a year and dynamic view imaging was possible, bone fusion was seen in 93% of the trauma cases and 95% in the non-trauma cases and overall bone fusion was observed in 94% of the cases. Bone fusion was seen in 93% of the autobone cases, 95% of the allobone cases, and 94% of the Mesh cases. Radiologic changes were observed by comparing the lateral view after surgery ; kyphosis was seen in 53% of the autobone cases, in 70% of the allobone cases, and in 35% of Mesh cases ; in 45% and 60% of the non-trauma cases and trauma cases, respectively ; and in 55% of the 2 level fusion cases and 46% of the 3 level fusion cases. Neurologic changes classified according to Odom criteria showed excellent result in 48% of all the cases, good in 23%, fair in 4%, and poor in 25%. Conclusion : Even those cases with multi-level fusion, a high fusion rate could be obtained by performing anterior interbody fusion and internal fixation ; those cases with kyphosis were related more with the presence or absence of posterior compartment injury rather than the fusion level ; and those trauma cases showed not much difference in the fusion rate compared with non-trauma cases but had a high possibility of kyphosis.

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Preliminary Experience with Cervical Implantable Titanium Cage(RABEA) in Patients with Monosegmental Degenerative Disease : Clinical and Radiological Outcomes without Cancellous Bone Filling into Cage (단일 분절 퇴행성 경추질환에서 Titanium Cage를 이용한 전방 융합술의 조기 치험 : 골편 이식을 동반하지 않은 경우의 임상적 방사선학적 초기 결과)

  • Lee, Young-Kyun;Han, Young-Min;Kim, Jong-Tae;Chung, Dong-Sup;Park, Young-Sup;Park, Chun-Kun;Kang, Joon-Ki
    • Journal of Korean Neurosurgical Society
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    • v.30 no.sup2
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    • pp.300-308
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    • 2001
  • Objectives : Anterior cervical discectomy and interbody fusion has become a well-accepted surgical treatment of degenerative cervical diseases. Implatable cages have a stabilizing effect without plates and no need for autogenous bone graft. The authors evaluates the effect of implatable titanium cage(RABEA) on the clinical and radiological outcomes. Methods : 34 patients with symptomatic cervical degenerative diseases due to one level disc pathology were underwent anterior cervical discectomy and interbody fusion with titanium cages(RABEA) which were not filled with cancallous bone grafts from January 1999 to May 2001. Patients with osteoporosis and older than 65 years were not included. Among them, 15 patients could be followed-up for at least 1 year. The authors retrospectively reviewed the charts and radiographic data. Mean follow-up period was $1.3{\pm}0.2years$. Results : Clinical results according to the Odom's criteria was exellent and good in 14(93%) patients. One patient with fair result showed complete loss of the disc space height due to settlement of the cage. Preoperatively, the mean height of the disc space(${\pm}$standard deviation) was $3.42{\pm}1.10mm$(range 2.0-5.5mm), and at 1 day postoperatively it was $7.88{\pm}0.90mm$(range 6.50-9.0). The mean height of the disc space after 1 year was $6.50{\pm}1.38mm$(range 3.0-8.0). The restoration of the height was statistically significant(p<0.05). The mean height after 1 year was $82.7{\pm}15.9%$ of the height at 1 day postoperatively. Preoperatively the mean value of the cervical lodortic angle was $21.8{\pm}11.8^{\circ}$ and 1 year postopertively, it was $24.5{\pm}8.3^{\circ}$, which was statistically not significant. All patients showed no abnormal movements on flexion and extension lateral film after 6 months. Conclusion : Implantable titanium cages appear safe and effective in selected patients, and their use helps to avoid complications associated with bone graft harvest. Subsidence of the cage seems to be a potential risk factor for recurrence of the symptoms. For long-term results, a longer follow-up is required.

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Detection of the Factors Related to spermatization in Sclerotinia trifoliorum -I. Course of Fertilization (Sclerotinia trifoliorum의 Spermatization에 관여하는 요인(要因)의 검색(檢索) -I. 균(菌)의 수정과정(受精過程))

  • Uhm, Jae Youl;Kim, Young Tae
    • Current Research on Agriculture and Life Sciences
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    • v.5
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    • pp.127-133
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    • 1987
  • The process of fertilization and changes in anatomical structure of sclerotia during the apothecial formation in Sclerotinia trifoliorum, the causal fungus of sclerotial rot of forage legumes, were investigated. The time of fertilization could be estimated with fair accuracy by the sequencial spermatization of the sclerotia which kept at 15C in saturated moisture. In the case of one strain used in this experiment, fertilization between the sclerotia and spermatia were estimated to take place at around 18days after the sclerotia were placed under the conditions for apothecial induction (15C, saturated moisture). The fertilizable state was maintained for about 45 days and the spermatization thereafter did not induce the apothecial formation. When the sclerotia reached fertilizable state, a number of interwoven hyphal nests were developed within the medulla of sclerotia, regardless of the sexuality of the cultures. Comparing the process of multiplication and growth of the hyphal nests in homothallic and heterothallic culture, they were identified as ascogonium. These ascogonia were persisted for about 45 days. This observation was well coincided with the duration of fertilizable state elucidated by the sequencial spermatization experiment.

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Study of Selective Cell Drop Scheme using Fuzzy Logic on TCP/IP (TCP/IP에서 퍼지 논리를 사용한 선택적 셀 제거 방식에 관한 연구)

  • 조미령;양성현;이상훈;강준길
    • Journal of the Korea Computer Industry Society
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    • v.3 no.1
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    • pp.95-104
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    • 2002
  • This paper presents some studies on the Internet TCP/IP(Transmission Control Protocol-Internet Protocol) traffic over ATM(Asynchronous Transfer Mode) UBR(Unspecified Bit Rate) and ABR(Available Bit Rate) classes of service. Fuzzy logic prediction has been used to improve the efficiency and fairness of traffic throughput. For TCP/IP over UBR, a novel fuzzy logic based cell dropping scheme is presented. This is referred to as fuzzy logic selective cell drop (FSCD). A key feature of the scheme is its ability to accept or drop a new incoming packet dynamically based on the predicted future buffer condition in the switch. This is achieved by using fuzzy logic prediction for the production of a drop factor. Packet dropping decision is then based on this drop factor and a predefined threshold value. Simulation results show that the proposed scheme significantly improves TCP/IP efficiency and fairness. To study TCP/IP over ABR, we applied the fuzzy logic ABR service buffer management scheme from our previous work to both approximate and exact fair rate computation ER(Explicit cell Rate) switch algorithms. We then compared the performance of the fuzzy logic control with conventional schemes. Simulation results show that on zero TCP packet loss, the fuzzy logic control scheme achieves maximum efficiency and perfect fairness with a smaller buffer size. When mixed with VBR traffic, the fuzzy logic control scheme achieves higher efficiency with lower cell loss.

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The Effect of Corporate Social Responsibility Activities on Brand Equity and Consumer Attitude (사회적 책임활동이 브랜드자산과 소비자태도에 미치는 영향 연구)

  • Park, Nam-Goo;Choi, Ho-Gyu
    • Journal of Distribution Science
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    • v.12 no.8
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    • pp.17-29
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    • 2014
  • Purpose - The use of corporate social activities to implement the concept of corporate social responsibility enhances brand equity and attitude, and strengthens economic competitiveness. In areas such as mobile communications, companies take the responsibility of protecting customers and enhance the quality of the mobile communication service, helping to make an effort to obey the regulations of the public trade order and fair trade agreement, enabling a healthy society through communication with elderly living alone or youths without parents, and enhancing marketing strategies. Research design, data, and methodology - To test the hypothesis, a survey was conducted. The surveyed population includes people who use the big three mobile communication services. The survey was conducted from October 4th to October 14th, 2013. A total of 500 survey questionnaires were circulated and 483 were collected; out of these, 32 were excluded due to missing or incomprehensible information. The data was analyzed with SPSS 18.0 via frequency analysis, trust analysis, search factor analysis, relationship analysis, confirmation factor analysis using AMOS 18.0, and structural equation model analysis. Results - Research on corporate social responsibility has been frequently conducted recently. Companies are perceived as social constituents satisfying the social desires of people in addition to customer needs. Further, companies are returning profits to society to satisfy community needs, because there is greater emphasis on the social responsibilities of companies. Companies' social responsibilities should include marketing strategies and the identification of customer needs. This study shows that social service activities influence brand value, which influences customer attitudes; therefore, social service activities indirectly influence customer attitudes. In order to increase customers' purchasing intention, it is essential to improve brand image via social services and provide a distinctive quality of service. Conclusions - This research has used the purposive selection method in the empirical analysis to identify the effect of social services on brand value and customer attitude. Therefore, this study revealed that businesses, whose ultimate objective is to improve customers' purchasing intention, should promote their brand equity through corporate social responsibility activities and offer a distinct service quality. Limitations in the progress of research were found and future indications to overcome these limitations are suggested as follows. First, survey responders had a limited understanding of social responsibilities; therefore, this concept needs to be explained to people first. Second, the research was done on people who live in Daejeon; thus, it is not representative of the entire country. The research has to be repeated with people in other cities. Third, there is a limitation in the study because the purposive selection method was used on Daejeon customers. In the future, a more precise selection of the population is needed. Fourth, Daejeon has unique geographical and size characteristics. Thus, customers in Seoul and other areas may display different characteristics and research on them may reveal different findings. Therefore, again, this study has to be repeated in other areas.

Effects of the Support and Control of Franchisors on Franchisees' Satisfaction and Response Strategies (프랜차이즈 가맹본부의 지원, 통제가 가맹점사업자의 만족 및 반응전략에 미치는 영향)

  • Kwon, Yong-Deok;Yu, Jong-Pil
    • Journal of Distribution Science
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    • v.12 no.8
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    • pp.43-54
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    • 2014
  • Purpose - This study was based on a theoretical consideration of the structural relationship between the support and control of the franchisor and the satisfaction and strategic response (voice, loyalty, exit, neglect) of the franchisee. First, based on the preceding research, this study systematically organized the type of support and control of the franchisor. Second, the study examined the effects of a franchisor's support and control on the expectancy disconfirmation between affiliated franchisees' expectations before a franchise agreement and performance after operating an affiliated store. Third, the study looked into the effects of expectancy disconfirmation relating to a franchisor's support and control on an affiliated franchisees' general satisfaction. Fourth, this study examined the influence of the general satisfaction of a franchisee on affiliated franchisees' response strategies. Research design, data, and methodology - In this study, the population comprised the nation's franchisors, and the sample comprised franchisees conducting business in Seoul and Gyeonggi-do. A self-administered questionnaire was used; the author and examiner explained the study's parameters to the interviewees in advance, to lessen the rate of rejection of the answers and to maintain reliability. The author distributed 350 copies of the questionnaire and collected 327 copies (93.4%). The author removed 54 copies of the sample, as these copies belonged to franchisees that were not registered by the Fair Trade Commission and/or were thought to have either defects or inadequate answers. The author selected an effective sample of 273 copies to enter data and to do the statistical analysis. Results - Both a reliability analysis and a confirmatory factor analysis were performed to measure reliability and validity, and a structural equation model was used to conduct the hypothesis test and investigate the models. The hypothesis was tested (Table 5). The models had a suitable fit, for instance, χ2 = 447.663(df = 212, p = .000), χ2/df = 2.112, GFI = .881, AGFI = .858, RMR = .083, RMSEA = .067, NFI = .932, and CFI = .961. The hypothesis test results were as follows. Hypothesis 1 was accepted (C.R. = -2.339, p = .019). Hypothesis 2 was accepted (C.R. = 15.213, p = .000). Hypothesis 3 was accepted (C.R. = -2.631, p = .006). Hypothesis 4 was accepted (C.R. = 16.271, p = .000). Hypothesis 5 was accepted (C.R. = 2.391, p = .017). Hypothesis 6 was accepted (C.R. = 5.777, p = .000). Hypothesis 7 was accepted (C.R. = 17.153, p = .000). Hypothesis 8 was accepted (C.R. = 24.746, p = .000). Hypothesis 9 was accepted (C.R. = -10.150, p = .000). Hypothesis 10 was accepted (C.R. = -12.124, p = .000). Conclusions - The research results showed that expectations for a franchisor's support and control had a significant influence on expectation disconfirmation in a negative way, whereas the performance of support and control were found to have a significant influence on expectation disconfirmation in a positive way. In addition, the expectation disconfirmation of support and control was found to have a significant influence on satisfaction of franchisees in a positive way. Generally, regarding the research on control, control is found to have a negative influence on the satisfaction of franchisees, but this study proves that control is found to affect it in a positive way through conformity.