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고립된 왜소불규칙은하 NGC 1156의 새로운 거리 결정

  • Kim, Sang-Cheol;Park, Hong-Su;Gyeong, Jae-Man;Lee, Jun-Hyeop;Lee, Chang-Hui;Kim, Min-Jin
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.80.2-80.2
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    • 2012
  • 홀로 고립되어 존재하는 은하는 주변 은하와 상호작용을 하지 않은 채 진화하므로 은하의 진화를 연구하기에 아주 좋은 대상이다. 은하의 정량적 연구를 위해 꼭 알아야 하는 중요한 물리량으로 거리와 성간소광량이 있다. 우리는 허블 우주망원경(HST) Advanced Camera for Surveys(ACS)/High Resolution Channel(HRC)로 관측한 고립된 왜소불규칙은하 NGC 1156 ($RA_{2000}$=02:59:42.19, $DEC_{2000}$=+25:14:14.2) 중심부($26^{\prime\prime}{\times}29^{\prime\prime}$)의 archive 자료를 분석하여 이 은하의 거리와 성간소광량을 새로 구했다. 이 은하의 거리를 측정한 과거 자료는 Tully(1988, Nearby Galaxies Catalog) 목록과 Special Astrophysical Observatory 6m 망원경/VI(각 300s) 영상자료의 가장 밝은 별로 거리를 구한 Karachentsev et al. (1996) 자료 뿐이다. 우리는 HST/ACS/HRC+UBVI 자료 중 U자료를 이용하여 아주 신뢰할 만한 소광량 값($E(B-V)=0.35{\pm}0.05$)을 얻었고, 가장 밝은 빨간 별과 파란 별 자료를 이용하여 새로운 거리지수($(m-M)_0=29.39{\pm}0.20$, $d=7.6{\pm}0.7$ Mpc)를 결정했다. 이 거리 값은 과거의 값들(Tully $6.4{\pm}1.2$ Mpc; Karachentsev et al. $7.8{\pm}0.5$ Mpc)과 크게 다르지 않으며, 기존의 거리 자료들 역시 신뢰할만함을 보여준다. ACS/Wide Field Channel과 달리 ACS/HRC의 경우 등급 표준화 방정식이 완벽하지 않은데, 우리의 경우 F550M자료를 표준화할 수 없었다. 그러나 우리는 여러 파장, 많은 관측자료가 존재하는 47 Tucanae (NGC 104) 구상성단의 관측자료와 Padova 등연령곡선을 이용하여 성공적인 등급변환을 수행할 수 있었다.

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Fasudil Increases the Establishment of Somatic Cell Nuclear Transfer Embryonic Stem Cells in Mouse

  • So, Seongjun;Karagozlu, Mustafa Zafer;Lee, Yeonmi;Kang, Eunju
    • Journal of Animal Reproduction and Biotechnology
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    • v.35 no.1
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    • pp.21-27
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    • 2020
  • Somatic cell nuclear transfer derived embryonic stem cells (NT-ESCs) have significant advantages in various fields such as genetics, embryology, stem cell science, and regenerative medicine. However, the poor establishment of NT-ESCs hinders various research. Here, we applied fasudil, a Rho-associated kinase (ROCK) inhibitor, to develop somatic cell nuclear transfer (SCNT) embryos and establish NT-ESCs. In the study, MII oocytes were isolated from female B6D2F1 mice and performed SCNT with mouse embryonic fibroblasts (MEFs). The reconstructed NT-oocytes were activated artificially, and cultured to blastocysts in KSOM supplemented with 10 μM fasudil. Further, the blastocysts were seeded on inactivated MEFs in embryonic stem cell medium supplemented with 10 μM fasudil. A total of 26% of embryos formed into blastocysts in the fasudil treated group, while this ratio was 44% in the fasudil free control group. On the other hand, 30% of blastocysts were established NT-ESCs after exposure of fasudil, which was significantly higher than the control group (10%). The results suggest that fasudil reduced blastocyst development after SCNT due to inhibition of 2 cell cleavage while improved the establishment of NT-ESCs through the anti-apoptotic pathway.

Can Narrow Band Chirp Stimulus Shake the Throne of 500 Hz Tone Burst Stimulus for Cervical Vestibular Myogenic Potentials?

  • Ocal, F Ceyda Akin;Karacayli, Ceren;Coban, Volkan Kenan;Satar, Bulent
    • Journal of Audiology & Otology
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    • v.25 no.2
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    • pp.98-103
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    • 2021
  • Background and Objectives: The aim of the study was to compare effects of tone-burst (TB) and narrow-band (NB) Claus Elberling (CE)-chirp stimuli on amplitude, latency and interaural asymmetry ratio (IAR) of cervical vestibular evoked myogenic potentials (cVEMP) in healthy individuals. Subjects and Methods: The study included 50 healthy volunteers. cVEMP procedure was carried out using 500 Hz TB and NB-CE-chirp stimulus (360-720 Hz, up-chirp) in random order. cVEMP were recorded at 100 dB nHL. For each ear and each stimulus, P1 latency, N1 latency and P1N1 amplitude were measured. IAR was also calculated. Results: Mean age was 26.66±9.48 years. cVEMP's in response to both TB and NB CE-chirp stimuli were obtained in all subjects. No statistically significant difference in P1 latency, N1 latency, and P1N1 amplitude was found between the right and left ears for both TB and NB CE-chirp stimuli (p>0.05). In both sides, P1 and N1 latencies were significantly shorter in NB CE-chirp stimulation compared to TB stimulation (p=0.000). In both sides, no statistically significant difference was found in P1N1 amplitude between two types of stimuli (p>0.05). Conclusions: The chirp stimulus produces robust but earlier cVEMP than TB does. This largest series study on NB chirp cVEMP shows that NB chirp is a good and new reliable alternative.

Can Narrow Band Chirp Stimulus Shake the Throne of 500 Hz Tone Burst Stimulus for Cervical Vestibular Myogenic Potentials?

  • Ocal, F Ceyda Akin;Karacayli, Ceren;Coban, Volkan Kenan;Satar, Bulent
    • Korean Journal of Audiology
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    • v.25 no.2
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    • pp.98-103
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    • 2021
  • Background and Objectives: The aim of the study was to compare effects of tone-burst (TB) and narrow-band (NB) Claus Elberling (CE)-chirp stimuli on amplitude, latency and interaural asymmetry ratio (IAR) of cervical vestibular evoked myogenic potentials (cVEMP) in healthy individuals. Subjects and Methods: The study included 50 healthy volunteers. cVEMP procedure was carried out using 500 Hz TB and NB-CE-chirp stimulus (360-720 Hz, up-chirp) in random order. cVEMP were recorded at 100 dB nHL. For each ear and each stimulus, P1 latency, N1 latency and P1N1 amplitude were measured. IAR was also calculated. Results: Mean age was 26.66±9.48 years. cVEMP's in response to both TB and NB CE-chirp stimuli were obtained in all subjects. No statistically significant difference in P1 latency, N1 latency, and P1N1 amplitude was found between the right and left ears for both TB and NB CE-chirp stimuli (p>0.05). In both sides, P1 and N1 latencies were significantly shorter in NB CE-chirp stimulation compared to TB stimulation (p=0.000). In both sides, no statistically significant difference was found in P1N1 amplitude between two types of stimuli (p>0.05). Conclusions: The chirp stimulus produces robust but earlier cVEMP than TB does. This largest series study on NB chirp cVEMP shows that NB chirp is a good and new reliable alternative.

Deep Learning for Classification of High-End Fashion Brand Sensibility (딥러닝을 통한 하이엔드 패션 브랜드 감성 학습)

  • Jang, Seyoon;Kim, Ha Youn;Lee, Yuri;Seol, Jinseok;Kim, Seongjae;Lee, Sang-goo
    • Journal of the Korean Society of Clothing and Textiles
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    • v.46 no.1
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    • pp.165-181
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    • 2022
  • The fashion industry is creating innovative business models using artificial intelligence. To efficiently utilize artificial intelligence (AI), fashion data must be classified. Until now, such data have been classified focusing only on the objective properties of fashion products. Their subjective attributes, such as fashion brand sensibilities, are holistic and heuristic intuitions created by a combination of design elements. This study aims to improve the performance of collaborative filtering in the fashion industry by extracting fashion brand sensibility using computer vision technology. The image data set of fashion brand sensibility consists of high-end fashion brand photos that share sensibilities and communicate well in fashion. About 26,000 fashion photos of 11 high-end fashion brand sensibility labels have been collected from the 16FW to 21SS runway and 50 years of US Vogue magazines beginning from 1971. We use EfficientNet-B1 to establish the main architecture and fine-tune the network with ImageNet-ILSVRC. After training fashion brand sensibilities through deep learning, the proposed model achieved an F-1 score of 74% on accuracy tests. Furthermore, as a result of comparing AI machine and human experts, the proposed model is expected to be expanded to mass fashion brands.

The non-saponin fraction of Korean Red Ginseng ameliorates sarcopenia by regulating immune homeostasis in 22-26-month-old C57BL/6J mice

  • Oh, Hyun-Ji;Jin, Heegu;Lee, Boo-Yong
    • Journal of Ginseng Research
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    • v.46 no.6
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    • pp.809-818
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    • 2022
  • Background: The non-saponin fraction (NSF) of Korean Red Ginseng is a powder in which saponin is eliminated from red ginseng concentrate by fractionation. In this study, we examined the effect of NSF on age-associated sarcopenia in old mice. Methods: NSF (50 or 200 mg/kg/day) was administered orally daily to young (3-6-month-old) and old (20-24-month-old) C57BL/6 J mice for 6 weeks. Body weight and grip strength were assessed once a week during the oral administration period. The gastrocnemius and quadriceps muscle were excised, and the muscle fiber size was compared through hematoxylin and eosin staining. In addition, the effect of NSF on sarcopenia and inflammation/oxidative stress-related factors in hindlimb muscles was investigated by western blotting. Flow cytometry analysis was conducted to investigate the effect of NSF on immune homeostasis. Blood samples were collected by cardiac puncture, and the serum levels of insulin-like growth factor 1, pro-inflammatory cytokines, and glutathione were evaluated. Results: NSF significantly alleviated muscle strength, mass, and also fiber size in old mice. Age-associated impairment of immune homeostasis was recovered by NSF through retaining CD11b+F4/80+ macrophages and regulating inflammatory biomarkers. NSF also decreased the age-induced expression of oxidative stress factors. Taken together, NSF showed the effect of improving sarcopenia by inhibiting low-grade chronic inflammatory/oxidative stress factors. Conclusion: NSF exhibited anti-sarcopenia effects by regulating chronic inflammation and oxidative stress in old mice. Thus, we suggest that NSF is a promising restorative agent that can be used to improve sarcopenia in the elderly as well as maintain immune homeostasis.

COVID-19 Diagnosis from CXR images through pre-trained Deep Visual Embeddings

  • Khalid, Shahzaib;Syed, Muhammad Shehram Shah;Saba, Erum;Pirzada, Nasrullah
    • International Journal of Computer Science & Network Security
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    • v.22 no.5
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    • pp.175-181
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    • 2022
  • COVID-19 is an acute respiratory syndrome that affects the host's breathing and respiratory system. The novel disease's first case was reported in 2019 and has created a state of emergency in the whole world and declared a global pandemic within months after the first case. The disease created elements of socioeconomic crisis globally. The emergency has made it imperative for professionals to take the necessary measures to make early diagnoses of the disease. The conventional diagnosis for COVID-19 is through Polymerase Chain Reaction (PCR) testing. However, in a lot of rural societies, these tests are not available or take a lot of time to provide results. Hence, we propose a COVID-19 classification system by means of machine learning and transfer learning models. The proposed approach identifies individuals with COVID-19 and distinguishes them from those who are healthy with the help of Deep Visual Embeddings (DVE). Five state-of-the-art models: VGG-19, ResNet50, Inceptionv3, MobileNetv3, and EfficientNetB7, were used in this study along with five different pooling schemes to perform deep feature extraction. In addition, the features are normalized using standard scaling, and 4-fold cross-validation is used to validate the performance over multiple versions of the validation data. The best results of 88.86% UAR, 88.27% Specificity, 89.44% Sensitivity, 88.62% Accuracy, 89.06% Precision, and 87.52% F1-score were obtained using ResNet-50 with Average Pooling and Logistic regression with class weight as the classifier.

Effects of Hospital Ethical Climate and Communication Self-Efficacy on Nursing Cares Left Undone among Nurses (간호사의 병원윤리풍토와 의사소통 자기효능감이 미완료간호에 미치는 영향)

  • Noh, Yoon Goo;Sim, Bong Hee;Lee, Eun Su
    • Korean Journal of Occupational Health Nursing
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    • v.32 no.1
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    • pp.20-29
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    • 2023
  • Purpose: This study aimed to identify the effects of hospital ethical climate and communication self-efficacy on nursing care left undone. Methods: The participants were 142 nurses working in a general hospital. Data were collected from July 18 to August 30, 2021. Data were analyzed by t-test, ANOVA, Pearson correlation, and multiple regression analysis using the SPSS/WIN 25.0 program. Results: (a) The mean value of hospital ethical climate was 3.54±0.41, communication self-efficacy was 5.03±0.81, and the sum of nursing cares left undone was 3.68±3.14. (b) Nursing cares left undone had a negative correlation with hospital ethical climate(r=-.25, p=.003) but not with communication self-efficacy (r=-.13, p=.116). (c) Factors that affected nursing cares left undone included education (≥master) (β=.23, p=.005), marital status (single) (β=-.19, p=.018), age (26~27) (β=-.18, p=.022), and hospital ethical climate (β=-.18, p=.029); the explanation power was 18.0% (F=8.66, p<.001). Conclusion: Our study shows that hospital ethical climate plays a significant role in nursing cares left undone of nurses. It is important to strengthen hospital ethical climate to lower the incidence of nursing cares left undone. These results may serve as basic data to help develop strategies for reducing the incidence of nursing cares left undone.

Characteristics of Phytoplankton Succession Based on the Functional Group in the Enclosed Culture System (대형 배양장치에서 기능그룹에 기초한 식물플랑크톤 천이 특성)

  • Lee, Kyung-Lak;Noh, Seongyu;Lee, Jaeyoon;Yoon, Sungae;Lee, Jaehak;Shin, Yuna;Lee, Su-Woong;Rhew, Doughee;Lee, Jaekwan
    • Korean Journal of Ecology and Environment
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    • v.50 no.4
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    • pp.441-451
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    • 2017
  • The present study was conducted from August to December 2016 in a cylindrical water tank with a diameter of 1 m, a height of 4 m and a capacity of 3,000 L. The field water and sediment from the Nakdong River were also sampled for the experimental culture (field water+sediment) and control culture (field water), respectively. In this study, we aimed to investigate phytoplankton succession pattern using the phytoplankton functional group in the enclosed culture system. A total of 50 species in 27 genera including Chlorophyceae (30 species), Bacillariophyceae (11 species), Cyanophyceae (7 species), and Cryptophyceae (2 species) were identified in the experimental and control culture systems. A total of 19 phytoplankton functional groups (PFGs) were identified, and these groups include B, C, D, F, G, H1, J, K, Lo, M, MP, N, P, S1, $T_B$, $W_0$, X1, X2 and Y. In particular, $W_0$, J and M groups exhibited the marked succession in the experimental culture system with higher biovolumes compared to those of the control culture system, which may be related to the internal cycling of nutrients by sediment in the experimental culture system. The principal component analyses demonstrated that succession patterns in PFG were associated with the main environmental factors such as nutrients(N, P), water temperature and light intensity in two culture systems. In conclusion, the present study showed the potential applicability of the functional group for understanding the adaptation strategies and ecological traits of the phytoplankton succession in the water bodies of Korea.

Effects of Experimental Warming on Physiological Responses of Four Deciduous Tree Species Seedlings (실외 실험적 온난화 처리에 따른 활엽수 4개 수종 묘목의생리적 반응)

  • An, Jiae;Han, Seung Hyun;Chang, Hanna;Park, Min Ji;Son, Yowhan
    • Journal of Korean Society of Forest Science
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    • v.105 no.4
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    • pp.510-516
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    • 2016
  • This study was conducted to investigate the physiological responses of newly-germinated seedlings of Fraxinus rhynchophylla Hance, Zelkova serrata (Thunb.) Makino, Betula costata Trautv. and Quercus variabilis Blume to open-field experimental warming. The seedlings in the warmed plots were warmed with $2.7^{\circ}C$ higher air temperature than those in the control plots using infrared heaters since April, 2015. Physiological responses (stomatal conductance, transpiration rate, chlorophyll content and net photosynthetic rate) to experimental warming varied with the species and the time of the measurement. Stomatal conductance ($mmol{\cdot}m^{-2}{\cdot}s^{-1}$) tended to decrease for F. rhynchophylla (Control: $158.97{\pm}42.76$; Warmed: $42.07{\pm}8.24$), Z. serrata (Control: $170.53{\pm}27.22$; Warmed: $101.17{\pm}42.27$) and B. costata (Control: $249.93{\pm}47.39$; Warmed: $150.73{\pm}26.52$). Transpiration rate ($mmol{\cdot}m^{-2}{\cdot}s^{-1}$) also decreased for F. rhynchophylla (Control: $4.08{\pm}0.62$; Warmed: $1.74{\pm}0.39$), Z. serrata (Control: $4.32{\pm}0.44$; Warmed: $3.24{\pm}1.14$) and B. costata (Control: $6.21{\pm}0.38$; Warmed: $4.66{\pm}0.28$). However, warming exhibited only minimal effects on stomatal conductance and transpiration rate of Q. variabilis seedlings. Chlorophyll content increased by the warming treatment while the effect of warming was not significant on net photosynthetic rate, since the warming treatment had a weak influence for changing net photosynthetic rate.