• 대한안과학회지
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• 제59권11호
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• pp.1087-1090
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• 2018

목적: 중뇌(midbrain) 등쪽(dorsal)의 사구수조지방종(quadrigeminal cistern lipoma)에 의한 도르래신경마비를 경험하였기에 이를 보고하고자 한다. 증례요약: 65세 남자가 2년 전부터 간헐 양안 수직 복시가 있었으나 별다른 치료 없이 지내다가 2주 전부터 항상 증상이 생겨 내원하였다. 1달 전 진단받은 당뇨 이외에 다른 전신질환의 과거력은 없었다. 시력은 우안 20/25, 좌안 20/20이었고, 상대구심동공운동장애는 없었다. 안구운동검사에서 원거리 주시에서 4프리즘디옵터(prism diopters, PD)의 좌안 상사시와 근거리에서 4PD의 외사시를 보였다. 좌안은 내전시상전(elevation in adduction)이 있었다. 머리기울임검사에서 좌측 기울임에서 6PD의 좌안 상사시가 보였고, 우측 기울임에서는 정위를 보였다. 안저검사에서 우안 외회선과 좌안 내회선이 보였다. 뇌자기공명영상(brain magnetic resonance imaging)에서 중뇌 등쪽에서 나오는 도르래신경에 인접한 사구수조지방종을 확인하였다. 복시 증상의 완화를 위해 프리즘 안경을 처방하였고, 다른 신경 증상을 동반하지 않아 뇌 병변에 대한 경과관찰을 시행하기로 하였다. 결론: 중뇌 등쪽의 사구수조지방종으로 인해 도르래신경마비를 확인하였다. 종양의 압박에 의한 도르래신경마비는 드물지만, 본 증례와 같이 비특이적인 증상을 보인 도르래신경마비 환자에서는 빠른 뇌영상검사가 원인 감별에 도움을 줄 수 있다.

• Journal of Veterinary Science
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• 제22권5호
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• pp.65.1-65.12
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• 2021

Background: To assess the normal retina of the pigeon eye using spectral domain optical coherence tomography (SD-OCT) and establish a normative reference. Methods: Twelve eyes of six ophthalmologically normal pigeons (Columba livia) were included. SD-OCT images were taken with dilated pupils under sedation. Four meridians, including the fovea, optic disc, red field, and yellow field, were obtained in each eye. The layers, including full thickness (FT), ganglion cell complex (GCC), thickness from the retinal pigmented epithelium to the outer nuclear layer (RPE-ONL), and from the retinal pigmented epithelium to the inner nuclear layer (RPE-INL), were manually measured. Results: The average FT values were significantly different among the four meridians (p < 0.05), with the optic disc meridian being the thickest (294.0 ± 13.9 ㎛). The average GCC was thickest in the optic disc (105.3 ± 27.1 ㎛) and thinnest in the fovea meridian (42.8 ± 15.3 ㎛). The average RPE-INL of the fovea meridian (165.5 ± 18.3 ㎛) was significantly thicker than that of the other meridians (p < 0.05). The average RPE-ONL of the fovea, optic disc, yellow field, and red field were 91.2 ± 5.2 ㎛, 87.7 ± 5.3 ㎛, 87.6 ± 6.5 ㎛, and 91.4 ± 3.9 ㎛, respectively. RPE-INL and RPE-ONL thickness of the red field meridian did not change significantly with measurement location (p > 0.05). Conclusions: Measured data could be used as normative references for diagnosing pigeon retinopathies and further research on avian fundus structure.

• 한방안이비인후피부과학회지
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• 제31권2호
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• pp.152-159
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• 2018

Objectives : The aim of this study is to report the effect of Korean medicine treatment on diabetic retinopathy vitreous hemorrhage. Methods : A 66-year-old female who had diabetes for over 20 years showed vitreous hemorrhage of Grade 4 at initial visit. For about 2 months, acupuncture, moxibustion and herbal medicine treatment were performed. Prognosis was confirmed by funduscopic examination, automatic refractive examination and visual acuity test. Results : In the fundus photographs, we can observe the recovery of turbidity in Grade 4, which decreases to Grade 1, and the result of refraction in the right eye and visual acuity that was not measured when the turbidity is severe. Conclusions : This study was a case of a patient with diabetic retinopathy vitreous hemorrhage complaining of decreased visual acuity. Patients were given herbal medication, acupuncture and moxibustion. Through the funduscopic examination, the treatment effect on the absorption of vitreous hemorrhage was confirmed.

• Journal of Yeungnam Medical Science
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• 제23권2호
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• pp.227-231
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• 2006

기도가 닫힌 상태에서 강하게 숨을 뿜어내는 발살바법은 망막의 정맥압을 상승시키고 이에 따라 망막 출혈을 유발시킬 수 있다. 힘든 배변을 경험한 55세 남자가 우안의 중심시력 감소로 인해 본원을 방문하였다. 전신적인 질환으로 고혈압, 만성 변비를 앓고 있었고 동공을 산대하여 정밀 안저검사를 한 결과 유두 한 개 정도 크기의 망막전 출혈과 황반와주위로 작은 크기의 망막내 출혈이 관찰되었다. 특별한 치료없이 망막 출혈은 자연 흡수되어 시력은 정상으로 회복되었다. 배변으로 인해 급작스런 시력감퇴를 나타낸 발살바 망막증을 경험하였기에 보고하는 바이다.

• 한국임상수의학회지
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• 제26권5호
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• pp.480-482
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• 2009

A 2-year-old, castrated male, Scottish fold cat was referred to Veterinary Medical Teaching Hospital of Seoul National University (VMTH-SNU) for evaluation of acute bilateral blindness after general anesthesia. For dental prophylaxis in local animal hospital, general anesthesia had been induced with intravenous acepromazine and ketamine, and maintained with isoflurane after intubation. At VMTH-SNU on next day, complete blood count, electrolytes and serum chemistry values were within normal ranges. On neurologic examination, visual placing and postural reactions like as hopping, hemiwalking and wheelborrowing were reduced on right hindlimb. On ophthalmic examination, menace responses were absent on both eyes and pupillary light reflex (PLR) reduced on right eye, but other reflex and fundus were normal. Prednisolone (2 mg/kg sid for 3 days) was administrated orally and tapered. Visual placing was possible on 2nd day, and postural reactions were recovered on 4th day after dental prophylaxis. Based on the process and recovery, this case was considered as postoperative visual loss (POVL) after general anesthesia.

• Journal of Yeungnam Medical Science
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• 제41권4호
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• pp.300-305
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• 2024

Cytomegalovirus (CMV) retinitis is a rare disease, and overlapping manifestations involving the anterior segment are extremely uncommon. We report a patient who initially presented with persistent corneal edema and was later diagnosed with CMV retinitis. A 72-year-old man with uncontrolled intraocular pressure (IOP) in his right eye visited a tertiary hospital. At initial presentation, the IOP was 36 mmHg and the fundus was not clear due to corneal edema. Spectral domain optical coherence tomography revealed paracentral acute middle maculopathy (PAMM). Panretinal obstructive vasculopathy was observed on ultra-widefield fluorescein angiography. Three weeks later, trabeculectomy was performed to resolve the persistently high IOP. Once corneal edema improved, a white patch-like peripheral lesion and silver wire-like retinal vasculature were observed. Polymerase chain reaction of the aqueous humor was positive for CMV. Oral valganciclovir and intravitreal ganciclovir were administered as antiviral therapies. Despite treatment for 4 months, the final visual acuity was no light perception, with persistent corneal edema and neovascularization of the iris. We describe a rare case of the simultaneous occurrence of hypertensive uveitis and CMV retinitis. The presence of PAMM could be an initial identifiable sign of CMV retinitis, even in the presence of media opacity.

• 과학기술학연구
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• 제18권1호
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• pp.177-217
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• 2018

이 글은 사회문제 해결형 기술개발사업에서 진행된 리빙랩 활동을 검토하고 그 의의와 과제를 분석하고자 한다. 분석 사례는 2014년에서 2015년에 과학기술정보통신부(구 미래창조과학부)가 추진한 사회문제 해결형 기술개발사업 중 대표 사례인 '안저카메라 기술개발'과 '보행자 자동감지 시스템 개발'을 대상으로 한다. 분석 결과 두 사례 모두 리빙랩 방법론을 활용하여 기술개발부터 실용화 단계까지 사용자 참여형 연구개발 구조로 설계되었다. 즉 리빙랩은 최종 사용자의 지속적인 상호작용을 통해 최종 수요를 구체화하고, 제품과 서비스를 개선 실증할 수 있는 있는 하부구조로 기술-제품-서비스를 진화시키는 시스템으로 작동하였다. 1차 시도된 단계이나, 그 과정에서 최종 수혜자인 국민의 관점을 반영하면서 R&D 성과를 확산시키고 새롭게 일하는 방식을 만드는 계기를 만들어내고 있다. 향후 리빙랩이 확대되기 위해서는 중앙정부 및 지자체의 명확한 문제 인식과 일하는 방식의 변화가 필요하다. 또한 최종사용자, 매개사용자, 기업, 시민사회 등 관련 주체의 적극적인 참여 및 조직화를 필요로 한다. 현재 리빙랩 활동은 소수의 전문가가 의제를 주도하고 있기 때문에 다양한 리빙랩 실험과 함께 시행착오를 통한 학습 체계의 구축이 중요한 과제이다. 또한 현장지향성 문제해결을 위해서는 일반시민 담당 공무원을 포함한 과학기술자, 정책 전문가, 현장 활동가 등을 포함하는 다학제 초학제 연구팀의 구성과 운영이 필수적이다.

• 대한한의학회지
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• 제37권2호
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• pp.53-61
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• 2016

Objectives: Considering high prevalence of myopia in Asian countries, social cost paid for myopia may gradually increase in Korea. However, studies for developing myopia treatment are deficient. The study was to evaluate whether the periocular acupressure with a medical massager is effective for suppressing myopia progression. Methods: This study was an investigator-sponsored, prospective, open-labeled, and superiority pre and post single-armed study. 14 myopia children aged 7-12 years wore a medical massager for 15 minutes to stimulate periocular acupoints. For 24 weeks, the participants used the device twice a day. Based on prior studies, the refraction change of naturally proceeded myopia was set as -0.38 D. The axial length change of naturally proceeded myopia was set as 0.228 mm. To assess the safety, we performed vital sign check, physical examination, visual acuity test, slit lamp examination, IOP measurement, and fundus examination. Results: The refraction and axial length of the participants increased. For 24 weeks, the change in refraction was -0.38 D at the right eye and -0.40 D at the left. The change in axial length was 0.21 mm at the right and 0.22 mm at the left. In the safety assessment, any adverse event did not occur. Conclusions: There was no significant difference between the control group and the intervention group. The effect of growth may have more contributed to our result than that of acupressure. Based on our result, a full-scale study will not be conducted.

• 한방안이비인후피부과학회지
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• 제27권2호
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• pp.14-32
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• 2014

Objective : This study was carried out to analyze the trends of ophthalmology related articles that have been published in the Journal of Korean Medical Ophthalmology, Otolaryngology, Dermatology(JKOOD). Method : We studied 72 research papers relevant to Ophthalmology that published in JKOOD from 1988 to 2013. All the paper were classified into three categories; original article, review article and case report. We also analyzed the articles according to the sort of diseases. We sub-classified the original articles into three categories descriptive study, analytic study and experimental study. We analyzed the case report according to various types of treatment. Result : 1. The number of searched journals is 72 papers; 21 review articles, 18 original articles, 33 case reports 2. Classification of 18 original articles into three categories; 12 descriptive studies, 0 analytic study, 6 experimental studies. 3. Distribution of diseases in ophthalmology; the percentage of 'strabismus' ranked the highest(25%) in case report. 4. Method of Evaluation in retina disease ; the percentage of fundus photography ranked the highest(50%) Conclusions : It is needed to develop the methods of study in part of eye disease. The studies using modern medical equipment should be increased in ophthalmology of Korean Medicine. It will be helpful to obtain objectivity and increase quality of studies.

• 한국임상수의학회지
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• 제24권2호
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• pp.154-159
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• 2007

The objective of this retrospective study was to investigate the prevalence of retinal diseases in dogs presented to the Veterinary Medical Teaching Hospital, Seoul National University from April 2004 to December 2005. Sixty-five dogs (120 eyes) with retinal diseases involving blindness were included in this study. Age, breed, and gender data for all breeds were collected from medical records documenting vision loss. Generalized progressive retinal atrophy (gPRA) was the most common manifestation. Other prevalent findings included sudden acquired retinal degeneration (SARD) and retinal detachment (RD). Bilateral gPRA was found in 32 dogs with a female-to-male ratio of 1 : 1. The mean $age{\pm}SD$ of all dogs in this group was $4.66{\pm}2.30$ years with a range of 3 to 12 years. Breeds with highest prevalence of gPRA were Miniature Schnauzer (24/32, $mean{\pm}SD$ age: $3.79{\pm}0.78$ yr) and Poodle (2/32, $6.50{\pm}0.71$ yr). Twelve dogs (24 eyes) were diagnosed with SARD bilateraly, ranging from 3 to 13 years of age ($mean{\pm}SD:\;6.91{\pm}2.61$ yr). There were no abnormalities in fundus of 11 dogs at presentation. Electroretinography (ERG) without anesthesia was performed in 7 dogs, and all response was totally extinguished. Retinal detachment was identified in 21 dogs (32 eyes): 11 bilateral and 10 unilateral (7 right eye, 3 left eye). The most common breed was Shih Tzu (15/21, $mean{\pm}SD$ age: $4.39{\pm}3.24$ yr). Four other breeds comprised the remaining 6 cases (8 eyes). The everall mean age of the group was: $4.18{\pm}2.89$ years (range 0.8 to 14 years) with a female-to-male ratio of 1 : 1.1 (10 females, and 11 males).