• Title/Summary/Keyword: Extracellular

Search Result 3,597, Processing Time 0.028 seconds

Antigen Delivery Systems: Past, Present, and Future

  • Hyun-Jeong Ko;Yeon-Jeong Kim
    • Biomolecules & Therapeutics
    • /
    • v.31 no.4
    • /
    • pp.370-387
    • /
    • 2023

  • The COVID-19 pandemic has increased demand for safe and effective vaccines. Research to develop vaccines against diseases including Middle East respiratory syndrome, Ebolavirus, human immunodeficiency virus, and various cancers would also contribute to global well-being. For successful vaccine development, the advancement of technologies such as antigen (Ag) screening, Ag delivery systems and adjuvants, and manufacturing processes is essential. Ag delivery systems are required not only to deliver a sufficient amount of Ag for vaccination, but also to enhance immune response. In addition, Ag types and their delivery systems determine the manufacturing processes of the vaccine product. Here, we analyze the characteristics of various Ag delivery systems: plasmids, viral vectors, bacterial vectors, nanoparticles, self-assembled particles, natural and artificial cells, and extracellular vesicles. This review provides insight into the current vaccine landscape and highlights promising avenues of research for the development and improvement of Ag delivery systems.

  • https://doi.org/10.4062/biomolther.2023.006 인용 PDF

Bacillus sp. 세균이 생산하는 extracellular polysaccharides

  • 윤병대
    • The Microorganisms and Industry
    • /
    • v.18 no.1
    • /
    • pp.41-46
    • /
    • 1992

  • 본고에서는 현재 본 연구실에서 수행중인 3종의 Bacillus sp. 세균이 생산하는 ECP에 관한 물성연구결과 및 개발방향 등에 관해 기술하고, ECP에 관한 review는 국내.외적으로 발표한 우수한 논문들이 다수 있으므로 참고문헌의 소개만으로 생략한다.

  • PDF