• Journal of Integrative Natural Science
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• v.8 no.1
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• pp.1-12
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• 2015

CRTh2 receptor is an important mediator of the inflammatory effects and act as beneficial target for the treatment of asthma, COPD, allergic rhinitis and atopic dermatitis. In the present work, Hologram QSAR studies were conducted on a series of 50 training set CRTh2 antagonists (2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl acetic acids). The best HQSAR model was obtained using atoms, bonds, connections and donor/acceptor as fragment distinction parameter using hologram length 257 and 6 components with fragment size of minimum 7 and maximum 10. Significant cross-validated correlation coefficient ($q^2=0.786$) and non cross-validated correlation coefficients ($r^2=0.954$) were obtained. The model was then used to evaluate the 15 external test compounds which are not included in the training set and the predicted values were in good agreement with the experimental results ($r^2_{pred}=0.739$). Contribution map show that presence of C ring and its substituents makes big contributions for activities. The HQSAR model and analysis from the contribution map could be useful for further design of novel structurally related CRTh2 antagonists.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.4
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• pp.585-588
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• 1997

The polymerase chain reaction (PCR) technique was used to distinguish from two morphologically similar red algal species; Acrosorium polyneurum and A. yendoi. Total DNA was extracted by the LiCl method. The extracted DNA (15 ng) in a $25{\mu}\ell$ reaction volume was amplified by the PCR technique using primers covering with mitochondrial D-loop gene, nuclear rDNA internal transcribed spacer (ITS), and nuclear rDNA external transcribed spacer. A. yendoi could be distinguished from A. polyneurum on the producible basis of amplified ITS fragment of 650 bp.

• Journal of the Society of Naval Architects of Korea
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• v.53 no.2
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• pp.162-169
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• 2016

A new concept of membrane type LNG CCS was proposed. Also, its static behavior was numerically analyzed considering the interaction between primary and secondary barrier together with securing device. Hull deflection was taken into account as an external load, together with temperature distribution across the barriers. The suggested numerical model considers both sliding and contact between the two mating surfaces of both the primary and secondary barrier, and anisotropic material behavior of plywood, R-PUF was also taken into account. Furthermore, detailed local strength was evaluated for the securing device, which is arranged between two barriers to hold the primary barrier. It was confirmed through the numerical analysis that the new concept of membrane type CCS was structurally safe under static loading condition and securing concept was structurally reliable.

• Proceedings of the KIEE Conference
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• 1997.07f
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• pp.1971-1973
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• 1997

Space Vector control of linear induction motor without speed sensor is one of the most up-to-date researching subjects to the engineers in the fields of power electronics and control theory. A conveyance SLIM (Single-sided Linear Induction Motor) has required a stable speed and a soft start/stop when the goods convey. So, the close loop control method to use a speed sensor have been adopted and as the speed sensor, a linear encorder has been used. But when the speed sensor used, the application boundary is limited and the confidence of system is diminished because it is sensitive to external environment variations and its cost is very expensive. So, to solve these problems, this paper deals with speed control of the conveyance SLIM using space vector without speed sensorless.

• Journal of the Korean Society for Precision Engineering
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• v.17 no.4
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• pp.163-172
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• 2000

The postbuckling behavior and progressive damage of composite laminated cylindrical shell under uniform external pressure were investigated by nonlinear finite element method programming. For the finite element analysis, nine-node 3-D degenerated elements were utilized, and arc-length method including line search was adopted for the iteration and load-increment along postbuckling equilibrium path. As results. buckling load, postbucking behavior, and progressive failure f3r various composite laminated cylindrical shells were discussed.

• Journal of the Korea Safety Management & Science
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• v.9 no.3
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• pp.173-182
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• 2007

We suggested the policy of labor management in pump manufacturing industry through survey in order to improve competitive ability. In pump manufacturing industry, since it is difficult to find sufficient worker having technical skill and knowledge concerning pump manufacturing technology, therefore the industry must cultivate the employee systematically. We reached the result, production engineer and R&D engineer play an important role to improve competitive ability in pump manufacturing industry. Though they need technical education, the effect of education was not satisfactory. To solve this problem, suitable technical education course must be devised. Marketing reinforcement is a important factor in pump manufacturing industry. To achieve marketing reinforcement, each company must develop their present technology further and raise marketing ability to expand internal and external business. It is also consulted to use IT technology.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.10
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• pp.837-843
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• 2016

This paper presents a position control strategy for a pump-controlled electro-hydrostatic actuator (EHA) using feedforward control with disturbance compensation. As the disturbance observer is used to estimate nonlinear dynamics of EHA, which has valve-opening conditionals, as well as external disturbances, an additional feedforward control is adopted to achieve rapid response. The effectiveness of the proposed control strategy is verified through experiment using an EHA test bench. The proposed controller shows better tracking performance compared with a conventional PID controller.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2004.11a
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• pp.201-208
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• 2004

In this study a general Galerkin FE lubrication analysis method was utilized to analyze the complex lubrication performance of a spiral groove seal having an additional inner circular groove, which was designed for a chemical process mixer operating at a low speed of the maximum 500 rpm. Equilibrium seal clearance analyses under varying outer pressure revealed that the seal maintains a certain levitation seal clearance under the outer pressure of more than about 1.5 bar, regardless of a rotating speed. Also, under the normal outer pressure of 11 bar, the axial stiffness of the seal was predicted to have a high value of more than 7.0e+07 N/m, regardless of a rotating speed and thereby, the seal is expected to maintain a stable thickness of lubrication film under a certain external excitation acting.

• International Journal of Contents
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• v.13 no.2
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• pp.57-65
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• 2017

Recently, due to the significance of Industry 4.0, the manufacturing industry is developing globally. Conventionally, the manufacturing industry generates a large volume of data that is often related to process, line and products. In this paper, we analyzed causes of defective products in the manufacturing process using the decision tree technique, that is a well-known technique used in data mining. We used data collected from the domestic manufacturing industry that includes Manufacturing Execution System (MES), Point of Production (POP), equipment data accumulated directly in equipment, in-process/external air-conditioning sensors and static electricity. We propose to implement a model using C4.5 decision tree algorithm. Specifically, the proposed decision tree model is modeled based on components of a specific part. We propose to identify the state of products, where the defect occurred and compare it with the generated decision tree model to determine the cause of the defect.

• International Journal of Aeronautical and Space Sciences
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• v.18 no.2
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• pp.334-343
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• 2017

The optimum design of an SAR (Synthetic Aperture Radar) satellite constellation is developed herein using a genetic algorithm. The performance of Earth observations using a satellite constellation can be improved by minimizing the maximum revisit time. Classical orbit design using analytic methods has limitations when addressing orbit dynamics due to various disturbances. To overcome this issue, an optimization technique based on a genetic algorithm is used. STK (Systems Tool Kit) is utilized to propagate the satellite orbit when considering external disturbances, and the maximum revisit time on the earth observation area is calculated. By minimizing the performance index using a genetic algorithm, the optimum orbit of the satellite constellation is designed. Numerical results are provided to demonstrate the performance of the proposed method.