• Title/Summary/Keyword: Expression Form

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Anti-Proliferative and Anti-Carcinogenic Enzyme-inducing Activities of Delphinidin in Hepatoma Cells

  • Jang, Chan-Ho;Lee, In-Ae;Lim, Hyun-Ae;Kim, Ju-Ryoung;Ha, Young-Ran;Yu, Hoon;Sung, Mi-Kyung;Kim, Jong-Sang
    • Food Science and Biotechnology
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    • v.16 no.4
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    • pp.641-645
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    • 2007
  • Delphinidin, an aglycone form of anthocyanins, was demonstrated to have anti-carcinogenic potential. The compound at $50\;{\mu}g/mL$ caused a significant increase of quinone reductase activity, an anti-carcinogenic marker enzyme, in mouse hepatoma cell lines (Hepa1c1c7 and BPRc1). Delphinidin enhanced the expression of other detoxifying or antioxidant enzymes including glutathione s-transferase, gamma-glutamylcysteine synthetase, heme oxygenase 1, and glutathione reductase. It suppressed the proliferation of murine hepatoma cells in a dose-dependent manner, with approximately $IC_{50}$ of $70\;{\mu}g/mL$. These results suggest that delphinidin might be useful for cancer prevention.

Optimal sensing period in cooperative relay cognitive radio networks

  • Zhang, Shibing;Guo, Xin;Zhang, Xiaoge;Qiu, Gongan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.12
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    • pp.5249-5267
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    • 2016
  • Cognitive radio is an efficient technique to improve spectrum efficiency and relieve the pressure of spectrum resources. In this paper, we investigate the spectrum sensing period in cooperative relay cognitive radio networks; analyze the relationship between the available capacity and the signal-to-noise ratio of the received signal of second users, the target probability of detection and the active probability of primary users. Finally, we derive the closed form expression of the optimal spectrum sensing period in terms of maximum throughput. We simulate the probability of false alarm and available capacity of cognitive radio networks and compare optimal spectrum sensing period scheme with fixed sensing period one in these performance. Simulation results show that the optimal sensing period makes the cognitive networks achieve the higher throughput and better spectrum sensing performance than the fixed sensing period does. Cooperative relay cognitive radio networks with optimal spectrum sensing period can achieve the high capacity and steady probability of false alarm in different target probability of detection. It provides a valuable reference for choosing the optimal spectrum sensing period in cooperative relay cognitive radio networks.

Individual Channel Estimation Based on Blind Interference Cancellation for Two-Way MIMO Relay Networks

  • He, Xianwen;Dou, Gaoqi;Gao, Jun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.8
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    • pp.3589-3605
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    • 2018
  • In this paper, we investigate an individual channel estimation problem for multiple-input multiple-output (MIMO) two-way amplify-and-forward (AF) relay networks. To avoid self-interference during the estimation of the individual MIMO channels, a novel blind interference cancellation (BIC) approach is proposed based on an orthogonal preceding framework, where a pair of orthogonal precoding matrices is utilized at the source nodes. By designing an optimal decoding scheme, we propose to decompose the bidirectional transmission into a pair of unidirectional transmissions. Unlike most existing approaches, we make the practical assumption that the nonreciprocal MIMO channel and the mutual interference of multiple antennas are both taken into consideration. Under the precoding framework, we employ an orthogonal superimposed training strategy to obtain the individual MIMO channels. However, the AF strategy causes the noise at the terminal to be the sum of the local noise and the relay-propagated noise. To remove the relay-propagated noise during the estimation of the second-hop channel, a partial noise-nulling method is designed. We also derive a closed-form expression for the total mean square error (MSE) of the MIMO channel from which we compute the optimal power allocation. The simulation results demonstrate that the analytical and simulated curves match fully.

Headdress Designs appearing in Haute Couture Collection -Focused on 2010 S/S~2015 S/S- (오트 쿠튀르 컬렉션에 나타난 헤드드레스 디자인 -2010 S/S~2015 S/S 컬렉션을 중심으로-)

  • Choi, Jinyoung;Kim, Jiyoung
    • Journal of Fashion Business
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    • v.20 no.2
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    • pp.59-77
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    • 2016
  • The purpose of this study is to use data from studies of headdresses which might be helpful for creating new fashion styles. Headdresses in 2010 S/S-2015 S/S Paris haute couture collections were analyzed in the following categories: years, season, brand, type, color, material, and image. The types of headdresses were categorized as hat, hood, decorative or complex types. The hat type was elegant with a modern style, and coexisted with an exaggerated avant garde style. The hood type wrapped around the head with many examples having a distinctive sculpture on top of the knot. The decorative type varied dramatically in form and materials. The complex type was a blend of all the other types with the designer's individuality being outstanding. The characteristics of headdresses were revealed first, as an enlargement of the materials category, second, as an expression of dramatic forms, and third, as complete coordination of the creative fashion image. The headdresses illustrate the designer's creativity in producing a variety of images. Henceforth they will be important as fashion items and independent designs in fashion styling.

A Study on the Characteristics and Design of Korean Kitsch Fashion (국내(國內) 키치패션의 특성(特性)과 디자인 연구(硏究))

  • Seo, Seung-Mi;Yang, Sook-Hi
    • Journal of Fashion Business
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    • v.4 no.2
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    • pp.1-17
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    • 2000
  • Kitsch is one of the various mass-cultural phnomena in the late 20th century, with it's own new aesthetic value, 'self-expression' through 'destruction', denying the existing established way of thinking and escaping from the stereotypes or fixed ideas. This is called 'aesthetic inadequacy'. The purposes of this study are to examine the different preferences between the western and the domestic Kitsch Fashions to investigate the formative and aesthetic characteristics of domestic Kitsch Fashion based on substantial data, and to propose the creative Kitsch design. The results of this study are as follows; 1. The formative characteristics of domestic Kitsch Fashion are marked by amusement, disharmony, epicureanism, satire, and use of imitation. 2. Then, based on theoretic research, this study applies aesthetic characteristics of Kitsch to the creative design. According to the formative characteristics for Kitsch Fashion, the Design Concepts are developed in order of Optimism, Multi Form, Decadence Chic, Neo-Naturalism, and Poor Vintage. And the Fabric direction is given in Design Story with sub theme such as Cheerful, Game, Decadence, Environment, and Grunge.

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A Study on the Effect of Herbal-acupuncture with Acanthopanacis cortex solution on Arthritis (오가피약침(五加皮藥鍼)이 류마토이드 관절염(關節炎)에 미치는 실험적(實驗的) 연구(硏究))

  • Kim, Jun-Pyo;Lee, Byung-Ryul
    • Korean Journal of Acupuncture
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    • v.22 no.2
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    • pp.75-87
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    • 2005
  • Objective : The purpose of this study is to observe the effect of Herbal-cupuncture with Acanthopanacis cortex Herbal-Acupuncture Solution (AC-HAS) on rheumatoid arthritis. Methods : The author performed several experimental items : it is paw thickness, weight of spleen, expression of $CD4^+,\;CD8^+,\;B220^+$ in the spleen, production of IL-6, $TNF-{\alpha}$, and examination of histology. Results : The obstain results are summarized s follows. 1. Treatment group were significantly inhibited the incidence of arthritis, hind paw edema and index of arthritis of CIA mice. 2. Treatment group were significantly decreased splenetic weight 3. The number of $CD4^+,\;CD8^+,\;B220^+$ activated cells were significantly inhibited in treatment group. 4. Treatment group were significantly decreased the amout of IL-4, $TNF-{\alpha}$ of CIA mice.. 5. Treatment group were expressed form of new bone, synoviumin and new margine in histology imperison to control group. Conclusions : Taking all these observations into account, AC-HAS injection is considered to be effective in treating rheumatoid arthritis and put to practical use in future rheumatoid arthritis clinic.

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Effect of Glycyrrhizae Radix on the Expression of UDP-Glucuronosyltransferase-1A1 (UGT1A1) in Rat Liver

  • Moon, A-Ree;Lee, Song-Deuk
    • Biomolecules & Therapeutics
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    • v.4 no.3
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    • pp.280-284
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    • 1996
  • Licorice has been widely used in combination with other herbs or synthetic drugs for various disorders. In an effort to study the effect of licorice roots (Glycyrrhizae Radix, GR) and glycyrrhizin on the hepatic glucuronidation, we have previously found that the pretreatment of GR or glycyrrhizin for 6 days resulted in a marked increase in the enzymatic activity of 3-methylcholanthrene (3-MC)-inducible hepatic UDP-glucuronosyltransferase (UGT) isozyme that has high affinity toward phenolic substrates (p-nitrophenol form, UGTIA) in Sprague-Dawley rats. As an approach to elucidate the mechanism for the enzyme activation by licorice in rat liver, we examined the levels of hepatocellular mRNAs for UGTIA upon the treatment of GR or glycyrrhizin. The hepatic mRNAs were extracted from Sprague-Dawley rats and Wistar rats after the treatment of the methanol extract of GR (1 g/kg, p.o.), glycyrrhizin (23 mg/kg, p.o.) for 6 days, or 3-MC (40 mg/kg, i.p.) for 3 days. Using the UGT1A1 CDNA as a probe, we found that the mRNAs for the enzyme were induced by 3-MC treatment while those were influenced neither by GR nor by glycyrrhizin in both strains of rats. These results indicate that the activation of rat liver UGTI A by licorice and glycyrrhizin was not due to the induction of mRNAs for the enzyme.

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The construction of multivariable Reissner-Mindlin plate elements based on B-spline wavelet on the interval

  • Zhang, Xingwu;Chen, Xuefeng;He, Zhengjia
    • Structural Engineering and Mechanics
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    • v.38 no.6
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    • pp.733-751
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    • 2011
  • In the present study, a new kind of multivariable Reissner-Mindlin plate elements with two kinds of variables based on B-spline wavelet on the interval (BSWI) is constructed to solve the static and vibration problems of a square Reissner-Mindlin plate, a skew Reissner-Mindlin plate, and a Reissner-Mindlin plate on an elastic foundation. Based on generalized variational principle, finite element formulations are derived from generalized potential energy functional. The two-dimensional tensor product BSWI is employed to form the shape functions and construct multivariable BSWI elements. The multivariable wavelet finite element method proposed here can improve the solving accuracy apparently because generalized stress and strain are interpolated separately. In addition, compared with commonly used Daubechies wavelet finite element method, BSWI has explicit expression and a very good approximation property which guarantee the satisfying results. The efficiency of the proposed multivariable Reissner-Mindlin plate elements are verified through some numerical examples in the end.

Analytic Prediction of Friction Factors for Turbulent Flow in Longitudinally Finned Rod Bundles (길이 방향 핀이 달린 봉 다발에서의 난류 마찰계수 산출을 위한 해석적 방법)

  • Kim, Nae-Hyun;Hong, Sung-Deok;Kwon, Hyuk-Sung;Lee, Sang-Keun
    • Nuclear Engineering and Technology
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    • v.23 no.4
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    • pp.401-409
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    • 1991
  • This work is concerned with the development of an analytical model to predict the friction in longitudinally finned rod bundles. Such bundles are currently considered in KMRR design. The present model assumes the validity of the Law of the Wall over entire flow area. The flow channel area is divided into the interfin region and a number of element channels, and the algebraic form of the Law of the Wall is integrated over each element channel and interfin region to yield an analytic expression for the pressure drop. The model reasonably predicts the 6 fin KMRR data, and overpredicts the 8 fin data about 15 percent.

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Characterization of the NF-$textsc{k}$B Activation Induced by TR8, an Osteoclastogenic Tumor Necrosis Factor Receptor Family Member

  • Kim, Hong-Hee
    • Archives of Pharmacal Research
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    • v.22 no.5
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    • pp.454-458
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    • 1999
  • TR8 is a recently identified member of the tumor necrosis factor (TNF) receptor superfamily. TR8 seems to play important roles in bone metabolism as stimulation of this receptor with its ligand, TL8 or osteoclast differentiation factor (ODF), induced the differentiation and activation of osteoclasts. Despite its important biological functions, the biochemcial events ensuing form TR8 activation have not been revealed in detail. Most of TNF receptor family proteins provoke the activation of the NF-$textsc{k}$B transcription factor. In the present study, we examined the signaling potential of TR8 to induce NF-B activation. When overexpressed in a human embryonic kidney cell line by transient transfection, TR8 caused a strong activation of NF-$textsc{k}$B, which was further increased upon stimulation with TL8. The TR8-induced NF-B activation was abrogated by the co-expression of the TRAF6 mutnat lacking the Ring and zinc finger domains and that of the kinase-inactive mutant NIK. Taken together, our study suggests that the presence of intact TRAF6 and the kiase activity of NIK may be essential for TR8 to induce NF-$textsc{k}$B activation.

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