• Title/Summary/Keyword: Exposure doses

Search Result 559, Processing Time 0.026 seconds

Relationship between the Changes of Catecholamines and Blood Pressure Induced by Exposure to Low- and High-levels of Lead in Rats

  • Yoon, Suh-Young;Yoo, Kyeong-Seok;Cheong, Jae-Hoon
    • Biomolecules & Therapeutics
    • /
    • v.7 no.4
    • /
    • pp.322-328
    • /
    • 1999
  • In this study, it was tested whether the changes of catecholamines and its metabolites are related with the changes of blood pressure(BP) induced by different levels of lead exposure. Adult male SD rats were exposed to lead by giving drinking water containing 50(low doses), 200 and 1,000 ppm(high doses) of lead(as lead acetate) or sodium acetate(for control groups, supplying an identical amount of acetate) for 7 or 16 weeks. The systolic BP was measured in the unanesthetized state by the tail-cuff technique. Levels of catecholamines and its metabolites in urine were measured by HPLC-ECD. Rats receiving 200 and 1,000 ppm developed an elevation of systolic BP at 3 and 7 weeks compared with week 0, but blood pressure levels at 16 weeks returned to normal. For the 50 ppm lead treated group, systolic BP increased significantly at 7 weeks and 16 weeks. The concentrations of norepinephrine and VMA in the urine of lead exposed rats changed similarly to the changes of blood pressure, but blood viscosity levels in all lead treated rats increased continuously during all lead treatment periods. This result suggests that the changes of catecholamines and its metabolites in urine by lead intoxication may influence the changes of blood pressure.

  • PDF

Accumulation of Butyltin Compounds in Shellfish and Fish from Korean Coastal Areas

  • Choi, Hee-Gu;Kim, Sang-Soo;Moon, Hyo-Bang;Lee, Pil-Yong;Gu, Bon-Kyu
    • Journal of the korean society of oceanography
    • /
    • v.37 no.2
    • /
    • pp.82-89
    • /
    • 2002
  • Butyltins (BTs) were measured in 2 species of shellfish and 16 species of fish collected along the Korean coast. Tributyltin (TBT) was detected in the mussels and oysters of sentinel organisms (20 to 940 ng Sn/g dry wt), indicating widespread contamination of TBT in the Korean coast. The elevated concentrations of TBT in the shellfish found in the sites near harbors or shipyards suggested that antifouling paints are probable major sources of butyltins in these areas. The TBT compound was detected in 12 out of 16 fish samples. The concentrations of TBT in fish muscles wee between 7 and 151 ng Sn/g dry wt, while the level in whole body of anchovy was very high (793 ng Sn/g dry wt). Exposure doses to Korean people via consumption of these marine products wee evaluated. The results suggested that the environmental levels of TBT were below the level of concern.

Measurements and Assessments on Shielding Performance of FCTC10 60Co Transport Container

  • Zhuang, Dajie;Zhang, Guoqing;Li, Guoqiang;Wang, Renze
    • Journal of Radiation Protection and Research
    • /
    • v.41 no.3
    • /
    • pp.310-314
    • /
    • 2016
  • Background: FCTC10 container is designed to transport $^{60}Co$ radioactive sources used in irradiation industry. It belongs to Type B(U) Category III (yellow) package when being loaded with a $^{60}Co$ source of $1.8{\times}10^5$ Ci. Materials and Methods: The container is constituted of shielding container, basket, protective cover and bracket. Shielding ability is provided mainly by stainless steel shells, tungsten alloy and lead among steel shells. Radiation level around the container has been calculated with both Monte Carlo simulations and measurements. Results and Discussion: It is proven that the shielding performance of the container fulfills the requirements in GB11806-2004 (Regulations for the safe transport of radioactive material, China Standard Press). Exposure doses to workers and to critical groups of public were calculated based on hypothetical exposure scene according to transport practice experience. Conclusion: The results show that doses to workers and public are less than the constraint dose considered in design, and the radiation level would be increased less than a factor of 2 under design basis accidents.

The Experimental Study on Biochemical Changes of Rat Liver Following Single Irradiation of High Energy X-ray (고(高)에너지 방사선(放射線)을 1회조사(一回照射)한 흰쥐 간(肝)의 생화학적(生化學的) 변화(變化))

  • Lee, Joon-Il;Park, Myeong-Hwan;Park, Chong-Sam
    • Journal of radiological science and technology
    • /
    • v.16 no.2
    • /
    • pp.87-94
    • /
    • 1993
  • In order to investigate radiation effects on the liver, functional changes of liver were analyzed after irradiation. Doses of 10 Gy, 15 Gy and 20 Gy were exposed partially to the liver of male rats(Sprague-Dawley) with X-ray(4MV linear accelerator) at room temperature. On 1, 2, 4 and 8 weeks after irradiation, liver tissues and sera of the animals were compared with those of unirradiated animal by liver function tests. Enzyme activities in sera such as alanine aminotransferase, aspartate aminotransferase, malondialdehyde. The content of malondialdehyde in the activities of many enzymes including alanine aminotransferase, aspartate aminotransferase in sera were increased slightly with increasing exposure dose in all experiments and the activities of these enzymes increased markedly in 20 Gy irradiated groups. From these above results, functional changes of the liver were induced in all irradiated groups. Damaged liver was recovered along with time collapse after irradiation to the doses of 10 Gy and 15 Gy while no recovery was deteced within 8 weeks after irradiation to 20 Gy. These results suggest that careful attention must be paid to liver not to be included in exposure field in radiation therapy.

  • PDF

A Study on the Comparision of Performance between Three-phase Full-wave and Single-phase Full-wave X-ray Generators (삼상(三相)12펄스 전파정류장치(全波整流裝置)와 단상(單相) 전파정류장치(全波整流裝置)의 성능(性能) 비교(比較))

  • Kim, Young-Ill;Kim, Chang-Kyun;Huh, Joon
    • Journal of radiological science and technology
    • /
    • v.3 no.1
    • /
    • pp.81-86
    • /
    • 1980
  • To compare three-phase 12-pulse full-wave X-ray generators with single-phase full-wave X-ray generators on their performance of outputs, authors studied the generating X-ray by means of exposure dose and radiographic density. The results were as follows; 1. The exposure doses of three-phase full-wave X-ray generators showed a 30%-60% increase as compared against of single-phase full-wave generators. 2. The transmitted doses of three-phase full-wave generators were more increased than single-phase full-wave X-ray generators. 3. To obtain the same density, 60kVp in three-phase full-wave generators were equivalent to $60{\sim}65kVp$ in single-phase full-wave generators, and 100kVp in those generators were equivalent to $100{\sim}125kVp$ in these generators.

  • PDF

A Review of Radiation Field Characteristics and Field Tests for Estimating on the Extremity Dose under Contact Tasks with Radioactive Materials (방사성물질과 접촉하는 작업의 손·발이 받는 피폭방사선량 평가에 대한 고찰)

  • Kim, Hee-Geun;Kong, Tae-Young;Dong, Kyung-Rae;Choi, Eun-Jin
    • Journal of Radiation Industry
    • /
    • v.11 no.3
    • /
    • pp.123-130
    • /
    • 2017
  • Concerns about high radiation exposure to the hands of radiation workers who may contact with radioactive contamination on surfaces in a nuclear power plant (NPP) had been raised, and the Korean regulatory body required the extremity dose estimation during contact tasks with radioactive materials. Korean NPPs conducted field tests to identify the incident radiation to the hands of radiation workers who may contact with radioactive contamination during maintenance periods. The results showed that the radiation fields for contact tasks are dominated by high energy photons. It was also found that the radiation doses to the hands of radiation workers in Korean NPPs were much less than the annual dose limits for extremities. This approach can be applicable to measure and estimate the extremity dose to the hands of medical workers who handle the radioactive materials in a hospital.

Doses of Pediatric and X-ray Examination Assistants according to Changes in Pediatric X-ray Exposure Conditions (소아 X선 촬영조건 변화에 따른 소아 및 촬영보조자 선량)

  • Beom-Jin Jang;Ha-Yun Nam;Hye-Min Shin;Dong-Min Yun;Seung-Kook Lee;In-Hwa Jang;Sungchul Kim
    • Journal of radiological science and technology
    • /
    • v.46 no.5
    • /
    • pp.409-415
    • /
    • 2023
  • Although pediatric X-ray examinations are continuously increasing, there are not many studies on the radiation exposure to children and X-ray examination assistants according to X-ray Exposure conditions. Accordingly, we measured the radiation exposure dose of pediatric and X-ray examination assistants according to the standard guidelines and clinical average X-ray Exposure conditions when X-ray examination 10-year-old children. The effective dose and organ dose to pediatric were measured using an Dose area production meter and Monte Carlo-based PCXMC program, and the exposure dose of X-ray examination assistants was measured using an ion-chamber. When performing abdominal supine AP projection, the effective dose to children was up to 2.38 times higher under clinical average X-ray Exposure conditions than the standard guidelines. In addition, during abdominal supine AP projection, the radiation exposure dose to the X-ray examination assistants was highest on the hands at 0.0148 ~ 0.0709 mSv, and exposure dose could be reduced by up to 35% when wearing protective gloves. In conclusion, because the X-ray Exposure conditions used in clinical are unnecessarily high, unnecessary medical radiation exposure could be reduced if appropriate X-ray Exposure conditions and the radiation field area were minimized and the assistant wore shielding gloves.

Thyroid Doses in Children from Radioiodine following the Accident at the Fukushima Daiichi Nuclear Power Plant

  • Kim, Eunjoo;Kurihara, Osamu
    • Journal of Radiation Protection and Research
    • /
    • v.45 no.1
    • /
    • pp.2-10
    • /
    • 2020
  • Background: Huge amounts of radionuclides were released into the environment due to the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, which caused not only serious contamination on the ground, but also radiation exposure to the public. One problem that remains in performing the dose estimation is the difficulty of estimating the internal thyroid dose due to the intake of radioiodine (mainly, 131I) because of limitations to the human data available. Materials and Methods: The relevant papers were collected and reviewed by the authors. The results of thyroid dose estimates from different studies were tabulated for comparison. Results and Discussion: The thyroid dose estimates from the studies varied widely. The dose estimates by the United Nations Scientific Committee on the Effects of Atomic Radiation were higher than the others due to the ingestion dose being based on conservative assumptions. The dose estimates by Japanese experts were mostly below 20-30 mSv. The recent studies suggested that exposure on March 12, 2011 would be crucial for late evacuees from the areas near the FD-NPP because of the possible intake of short-lived radionuclides other than 131I. Further multilateral studies are vital to reduce uncertainties in the present dose estimations. Conclusion: The estimation of the thyroid doses to Fukushima residents still has many uncertainties. However, it is considered unlikely that the thyroid doses exceeded 50 mSv except in some extreme cases. Further multilateral studies are thus necessary to reduce the uncertainties in the present dose estimations.

Assessment of Occupational Dose to the Staff of Interventional Radiology Using Monte Carlo Simulations (몬테카를로 방법을 이용한 중재방사선시술자에 대한 선량평가)

  • Lim, Young-Khi
    • Journal of Radiation Protection and Research
    • /
    • v.39 no.4
    • /
    • pp.213-217
    • /
    • 2014
  • Medical operations and diagnosis using interventional radiology techniques have been increased. The management and monitoring of occupational radiation exposure to the staff of interventional radiology become important, specially because they stand in close proximity to the patient. The operational radiation protection quantity, Hp(10) which can be obtained from personal dosimeter do not always represent the effective dose to the staff. So, in this study, to estimate the critical organ doses to the staff of interventional radiology, Monte Carlo calculations with mathematical human phantom and dose measurements with personal dosimeters were carried out for the major interventional radiology procedures using C-arm. Results showed that the values of Hp(10) measured by personal dosimeters were higher than critical organ doses which were calculated. And the calculated dose to thyroids was much higher than those of other critical organ doses. For the proper radiation protection of the medical staff of interventional radiology, additional radiation protection for thyroids as well as for whole body shielding like wearing a lead apron should be considered.

Radiological safety analysis of a newly designed spent resin mixture treatment facility during normal and abnormal operational scenarios for the safety of radiation workers

  • Jaehoon Byun;Seungbin Yoon;Hee Reyoung Kim
    • Nuclear Engineering and Technology
    • /
    • v.55 no.5
    • /
    • pp.1935-1945
    • /
    • 2023
  • The radiological safety of workers in a newly developed microwave-based spent resin treatment facility was assessed based on work location and operational scenarios. The results show that the remote-operation room worker was exposed to maximum annual dose of 3.19E+00 mSv, which is 15.9% of the dose limit, thereby confirming radiological safety. Inside the pathway, annual doses in the range of 7.87E-02-2.07E-01 mSv were measured initially at the mock-up tank and later at the point between the spent resin separation and treatment parts. The dose of emergency maintenance workers was below the dose limit (4.08E-03-4.99E+00 mSv); however, before treatment (separation and microwave), the dose of maintenance and repair workers exceeded the dose limit. The doses of the effluent removal workers at the zeolite and activated carbon storage tank and spent resin storage tank were the lowest at 2.79E-01-2.87E-01 mSv and 9.27E-01 mSv in "1 h" and "4-5 h of operation", respectively. The immediately lower and upper layers of the facility room exhibited the highest annual doses of 1.84E+00 and 3.22E+00 mSv, respectively. Through this study, a scenario that can minimize the dose considering the movement of spent resin through the facility can be developed.