• Title/Summary/Keyword: Experimental formula

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Synergic Effects of Mixed Formula Consisted of Polycan and Calcium-gluconate on the Experimental Periodontitis and Alveolar Bone Loss in Rats

  • Lee, Won-Ho;Kim, Kyung Hu;Kang, Su Jin;Lee, Young Joon;Ku, Sae Kwang
    • Journal of Society of Preventive Korean Medicine
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    • v.18 no.1
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    • pp.125-138
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    • 2014
  • Objective : Polycan, exopolymers purified from Aureobasidium pullulans SM-2001 and calcium gluconate have been showed favorable inhibitory effects on the periodontitis and related alveolar bone losses through antioxidant and anti-inflammatory activities, respectively. In the present study, we intended to observe the possible synergic effects of mixed formula consisted of Polycan and calcium gluconate on ligation-induced experimental periodontitis and related alveolar bone losses in rats, and to select the fittest compositions for further developing as effective agents to ameliorate periodontal diseases. Method : Experiments were conducted as two separated two tests - first is synergic effects of Polycan and calcium gluconate 1:1, 1:9 and 9:1 mixtures, and second is 1:99, 2:98, 4:96, 8:92 and 1:9 mixtures. Experimental periodontal diseases were induced by ligature placed around the cervix of upper left incisior teeth of rats. One day after ligation placements, 200mg/kg of each single or mixed formulas of Polycan or/and calcium gluconate were orally administered for 10 days. The changes on the alveolar bone loss index and maxillary bone mineral density (BMD) were observed for detecting alveolar bone losses, and for anti-inflammatory effects, myeloperoxidase (MPO) activities and proinflammatory cytokine (tumor necrosis factor; TNF-${\alpha}$) contents were also evaluated in gingival tissues around ligature placed incisior teeth. The results of mixtures were compared with those of singe Polycan and calcium gluconate treated rat. Results : Each single or mixed formulas of Polycan or/and calcium gluconate favorably and significantly inhibited the inflammatory changes. The inhibitory effects of mixed formula consisted of Polycan and calcium gluconate 1:9 showed against periodontitis and related alveolar bone losses as compared with those of each Polycan and calcium gluconate single formula (p<0.05). In second experiment, Polycan and calcium gluconate 2:98, 4:96, 8:92 and 1:9 mixed formulas also showed significant increased anti-inflammatory and inhibitory effects against alveolar bone losses as compared with those of each single formula. Among them, Polycan and calcium gluconate 2:98 showed the highest efficacy against to ligation-induced experimental periodontitis and related alveolar bone losses. Conclusion : The results obtained in this study suggest that appropriated mixtures of Polycan and calcium gluconate showed synergic inhibitory effects against ligation-induced experimental periodontitis and related alveolar bone losses in rats. Moreover, Polycan and calcium gluconate 2:98 showed the highest efficacies in this experiment, suggesting the fittest composition for further developing as effective agents to ameliorate periodontal diseases.

Rotordynamic Analysis of a Labyrinth Seal Using the Moody's Friction-Factor Model (Moody 마찰계수식을 사용한 래버린스 실의 회전체 동역학적 해석)

  • Ha, Tae Woong
    • The KSFM Journal of Fluid Machinery
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    • v.2 no.3 s.4
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    • pp.52-58
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    • 1999
  • The leakage and rotordynamic coefficients of see-through type gas labyrinth seals are determined using a two-control-volume-model analysis with Moody's wall-friction-factor formula which is defined with a large range of Reynolds number and relative roughness. Jet flow theory are used for the calculation of the recirculation velocity in the cavity. For the reaction force from the labyrinth seal, linearized zeroth-order and the first-order perturbation equations are developed for small motion about a centered position. The leakage and rotordynamic coefficient results of the present analysis are compared with Scharrer's theoretical analysis using Blasius' wall-friction-factor formula and Pelletti's experimental results. The comparison shows that the present analysis using Moody's wall-friction-factor formula and Scharrer's theoretical analysis using Blasius' wall-friction-factor formula give the same results for a smooth seal surface and the range of Reynolds number less than $10^5$.

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Analysis of Primary and Secondary Thrust of a Metal Belt CVT Part I : New Formula for Speed Rtio-Torque-Thrust Relationship Considering Band Tension and Block Compression (금속벨트 CVT 의 구동 및 종동 드러스트 해석 Part I : 밴드 장력과 블록 압축력을 고려한 새로운 변속비-토크-트러스트 관계식)

  • 이희라;김현수
    • Transactions of the Korean Society of Automotive Engineers
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    • v.7 no.8
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    • pp.132-142
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    • 1999
  • In this paper, a new formula for primary and secondary thrust of metal belt CVT is proposed considering variation of band tension, block compression and active arc for each of the primary and secondary pulleys. For the secondary thrust, effective friction coefficient is introduced considering the effect of flange deflection. Nondimensional primary and secondary thrust of the metal belt CVT by the new formula agree well with the experimental results except for low torque range, $0\;<\;{\lambda}\;<\;0.2$ at speed ration i = 1.0. The new formula can be used in design of the primary and secondary thrusts control system for the metal belt CVT.

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A Study on the Measurement of the Personal Exposure Dose by Film Badge Dosimeter (필름배지선량계에 의한 개인피폭선량 측정에 관한 연구)

  • Chung, Woon-Kwan
    • Journal of Radiation Protection and Research
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    • v.19 no.1
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    • pp.37-50
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    • 1994
  • The experimental evaluation of exposure conversion formula using the relationship between optical photo-density, exposure dose and the quality of radiation characteristics of radiation energy to X-ray and ${\gamma}-rays$. The film badge dosimeter is analysed by exposure conversion formula which evaluate image fading characteristics for development time and directional characteristics for incident beam angle. In conclusion, exposure conversion formula evaluated of this study is satisfied with quality decision criterion of the film badge dosimeter.

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A Study on an Earthwork Calculation for Reclamation of the Harbor (해안매립을 위한 토공량 산정에 관한 연구)

  • Lee, Y.H;Mun, D.Y
    • Journal of Korean Port Research
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    • v.11 no.2
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    • pp.257-271
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    • 1997
  • The calculation of earthwork plays a major role in plan or design of many civil engineering projects and thus it has become very important to advanced the accuracy of earthwork calculation. The purpose of this paper is to calculate the excavation volume of terrain using a proposal area formular in eathwork volume determination for reclamation of the harbor. A proposal area formular by first and third equation is compared with end area, middle area, prismoidal formula by trapezoidal, simpson formular to excavation volume for an experimental terrian $1\sim12$. As a result of this study, algorithm of a proposal area formula by prismoidal formula should provide a better accuracy than end area, middle area, prismoidal formula by trapezoidal formular, simpson formular.

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A Numerical Study of Flame Spread of A Surface Forest Fire (지표화 산불의 화염전파 수치해석)

  • Kim, Dong-Hyun;Lee, Myung-Bo;Kim, Kwang-Il
    • 한국전산유체공학회:학술대회논문집
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    • 2008.03b
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    • pp.80-83
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    • 2008
  • The characteristics of the spread of a forest fire are generally related to the attributes of combustibles, geographical features, and meteorological conditions, such as wind conditions. The most common methodology used to create a prediction model for the spread of forest fires, based on the numerical analysis of the development stages of a forest fire, is an analysis of heat energy transmission by the stage of heat transmission. When a forest fire breaks out, the analysis of the transmission velocity of heat energy is quantifiable by the spread velocity of flame movement through a physical and chemical analysis at every stage of the fire development from flame production and heat transmission to its termination. In this study, the formula used for the 1-dimensional surface forest fire behavior prediction model, derived from a numerical analysis of the surface flame spread rate of solid combustibles, is introduced. The formula for the 1-dimensional surface forest fire behavior prediction model is the estimated equation of the flame spread velocity, depending on the condition of wind velocity on the ground. Experimental and theoretical equations on flame duration, flame height, flame temperature, ignition temperature of surface fuels, etc., has been applied to the device of this formula. As a result of a comparison between the ROS(rate of spread) from this formula and ROSs from various equations of other models or experimental values, a trend suggesting an increasing curved line of the exponent function under 3m/s or less wind velocity condition was identified. As a result of a comparison between experimental values and numerically analyzed values for fallen pine tree leaves, the flame spread velocity reveals has a error of less than 20%.

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A Study on the Construction of an Artificial Neural Network for the Experimental Model Transition of Surface Roughness Prediction Results based on Theoretical Models in Mold Machining (금형의 절삭가공에서 이론 모형 기반 표면거칠기 예측 결과의 실험적 모형 전환을 위한 인공신경망 구축에 대한 연구)

  • Ji-Woo Kim;Dong-Won Lee;Jong-Sun Kim;Jong-Su Kim
    • Design & Manufacturing
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    • v.17 no.4
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    • pp.1-7
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    • 2023
  • In the fabrication of curved multi-display glass for automotive use, the surface roughness of the mold is a critical quality factor. However, the difficulty in detecting micro-cutting signals in a micro-machining environment and the absence of a standardized model for predicting micro-cutting forces make it challenging to intuitively infer the correlation between cutting variables and actual surface roughness under machining conditions. Consequently, current practices heavily rely on machining condition optimization through the utilization of cutting models and experimental research for force prediction. To overcome these limitations, this study employs a surface roughness prediction formula instead of a cutting force prediction model and converts the surface roughness prediction formula into experimental data. Additionally, to account for changes in surface roughness during machining runtime, the theory of position variables has been introduced. By leveraging artificial neural network technology, the accuracy of the surface roughness prediction formula model has improved by 98%. Through the application of artificial neural network technology, the surface roughness prediction formula model, with enhanced accuracy, is anticipated to reliably perform the derivation of optimal machining conditions and the prediction of surface roughness in various machining environments at the analytical stage.

An Experimental Study of Pneumatic Damping at the Air Chamber for OWC type Wave Energy Device (OWC형 파력발전 공기챔버의 공기감쇠력 실험연구)

  • CHOI Hark-Sun;LEW Jae-Moon;HONG Seok-Won;KIM Jin-Ha
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2004.05a
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    • pp.138-144
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    • 2004
  • Pneumatic damping through a orifice type duct for OWC type wave energy device is studied experimentally. Forced oscillation tests are made to measure chamber pressure and velocity of air flaw through orifice. Pneumatic damping coefficient are deducted from the experimental research, and discussion are made far the influence of frequency, heave amplitude, and orifice size. Finally two formula are proposed for the estimation of non-dimensional pneumatic damping coefficient by regression analysis. The proposed formula proves to be a reliable method far practical application.

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Size-Effect Analyses of Shear Behavior in Reinforced Concrete Beams (철근콘크리트 보의 전단거동의 크기효과 해석)

  • 변근주;하주형;송하원
    • Proceedings of the Korea Concrete Institute Conference
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    • 1998.04a
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    • pp.321-326
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    • 1998
  • Shear failure of reinforced concrete beams is serious problem due to sudden brittle failure and many experimental results proved that size effect in shear behavior is an important feature of reinforced concrete members. For this reason, the structural safety of the reinforced concrete beams for shear has been checked by applying empirical design formula, which includes the size-effect, derived from experimental data. However, as the sizes of reinforced concrete members become extremely large, experiments sometimes become very difficult so that the formula or the experimental data could not be obtained and size-effect analyses of shear behavior become significant. In this study, size-effect analysis of shear behavior in reinforced concrete beams is performed by modeling tension stiffening/shear stiffening on reinforced concrete and the tension softening/shear softening on plain concrete. Then, the influences of models in the size-effect analyses of shear behavior in reinforced concrete beams are analyzed.

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Comparison of Accuracy of Stability Formulas for Breakwater Armor Stones (방파제 피복석 안정 공식의 정밀도 비교)

  • 서경덕;유동훈
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.15 no.3
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    • pp.186-189
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    • 2003
  • Various empirical formulas have been developed to describe the stability of breakwater armor stones. The Hudson formula is known to have needs to be refined in many ways. but it is most widely used because of its simplicity. The van der Meer formula is sometimes used for the cross-check, but it is not very popularly used due to its complexity and the uncertainty of the relevant parameters. Recently, on the other hand, Yoo(2003) proposed a formula of a simple form using a new non-dimensional number which is called 'action slope' (abbreviated as Yoo formula hereinafter). In this study, in order to provide coastal engineers with some idea of the use of these formulas, their accuracies were estimated by comparing with the experimental data reported by van der Meer in 1987 and 1988. It was found that the van der Meer formula showed the highest accuracy, while the Hudson formula of very low accuracy needed considered judgment on its use. On the other hand, the Yoo formula of slightly lower accuracy but simpler expression than the van der Meer formula seems to be able to be used in engineering practice if a slightly higher safety factor is taken.