• Clinical and Experimental Pediatrics
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• v.58 no.12
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• pp.505-508
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• 2015

It is uncommon for pediatric patients with rhabdomyosarcoma to present with clinical and/or laboratory features of disseminated intravascular coagulation (DIC). We report a case of metastatic alveolar rhabdomyosarcoma with severe bleeding because of DIC in a 13-year-old boy. He experienced persistent oozing at the site of a previous operation, gross hematuria, and massive epistaxis. Two weeks after initiating combination chemotherapy consisting of vincristine, doxorubicin, and cyclophosphamide, the patients' laboratory indications of DIC began to resolve. During this period, the patient received massive blood transfusion of a total of 311 units (26 units of red blood cells, 26 units of fresh frozen plasma, 74 units of platelet concentrates, 17 units of single donor platelets, and 168 units of cryoprecipitate), antithrombin-III and a synthetic protease inhibitor. Despite chemotherapy and radiation therapy, he died 1 year later because of disease progression. In children with metastatic rhabdomyosarcoma and massive DIC, prompt chemotherapy and aggressive supportive care is important to decrease malignancy-triggered procoagulant activities.

• Computers and Concrete
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• v.24 no.6
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• pp.561-570
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• 2019

Understanding the realistic behavior of concrete up to failure under different loading conditions within the framework of damage mechanics and plasticity would lead to an enhanced design of concrete structures. In the present investigation, QR (Quick Response) code based random speckle pattern is used as a non-contact sensor, which is an innovative approach in the field of digital image correlation (DIC). A four-point bending test was performed on RC beams of size 1800 mm × 150 mm × 200 mm. Image processing was done using an open source Ncorr algorithm for the results obtained using random speckle pattern and QR code based random speckle pattern. Load-deflection curves of RC beams were plotted for the results obtained using both contact and non-contact (DIC) sensors, and further, Moment (M)-Curvature (κ) relationship of RC beams was developed. The loading curves obtained were used as input data for material model parameters in finite element analysis. In finite element method (FEM) based software, concrete damage plasticity (CDP) constitutive model is used to predict the realistic nonlinear quasi-static flexural behavior of RC beams for monotonic loading condition. The results obtained using QR code based DIC are observed to be on par with conventional results and FEM results.

• Journal of the Korean Society of Safety
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• v.26 no.5
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• pp.27-32
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• 2011

Recently new technological development needs the advances in the fields of new materials. The most advanced design is not useful if new material's performance is not realized adequately for bearing the service loads and conditions. FGMs suggests the reasonable solution for the those requirements because of its wide range microstructure and the continuous constitutions. It's especially good for the heat-resisting components, piezoelectricity and aerocraft fields. However the fabrication and its experimental estimation methods have not been established because of its various freedom of material's properties. Therefore it is necessary to develope the fabrication method and estimation of strength and deformation. The experiments are conducted under a four point flexural test. According to results, this study shows that FGMs is well fabricated and the deformation and strain fields are expressed very well by digital image correlation method.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.4
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• pp.689-696
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• 1997

The effects of Aralia canescens and Phellodendron amurense(AP) extracts on the experimental diabetes in ICR mice were investigated. 96male ICR mice were induced diabetes mellitus by intrape-ritoneal streptozotocin injection(75mg/kg B.W.) and divided into two injection groups which are 5 day injection and 10 day injection group. Then, each injection group was subdivided into 8 groups of 6 animals repspectively. CIC served as control and CI1, CI2 and CI3 were treated with 50, 150, 250mg/kg B.W. of AP extracts powder in 0.9% NaCl solution. Animals of groups DIC, DI1, DI2 and DI3 were strepto-zotocin-induced diabetes. DIC served as diabetic control and the rest groups received 50, 150, 250mg/kg B.W of AP extracts powder in saline solution respectively. The body weight, liver and kiney weight changes and blood levels of glucose, cholesterol and triglyceride were measured. Thiobarbituric acid reactive substance(TBARS), and glutathione reductase(GR) and glutathione peroxidase(GPx) activities were also measured for determining antioxidant effects. AP extracts increased the body weight in diabetic groups. The liver and kidney weight/100g B.W. in DIC group were greater than those of normal ICR group but after AP extracts injection, liver and kidney weight were decreased significantly. These effects were more efficient at 10 days injection group. The total, LDL, VLDL cholesterol and triglyceride levels were significantly higher in DIC group and the extent of decrement responded to AP injection dose. The contents of TBARS and antioxidant enzyme activities were relatively decreased after AP extracts injection. These results suggest that the intraperitoneally administered AP extracts may have not only hypoglycemic effect but act as antioxidants by reducing lipid peroxidation.

• Journal of the Korean housing association
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• v.24 no.3
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• pp.27-35
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• 2013

The purpose of this study is to develop an evaluation system for integrative comfort values of Hanok residence. For this study, a mock-up located in Yongin, Gyeonggi province built by an ongoing governmental research project has been chosen. Then, SSN (Smart Sensor Network) has been utilized for monitoring quantitative factors in the environment and detailed face-to-face surveys have been performed for analyzing qualitative comfort indexes from residents in the experimental settings. Then, this study employs a combined evaluation system using AHP (Analytic Hierarchy Process) established for estimating overall DIC (Degree of Integrative Comfort) of the Hanok residence. As a result, the evaluation system could verify the total comfort indexes of Hanok residence and suggest converged methodologies for establishing value assessment system for traditional residential facilities. The method of DIC suggested in this paper would be examined with current residents in a built mock-up to see its applicability as a comprehensive evaluation model, and it is expected that collected year-round comfort data from the facility would provide more practical information towards future strategies for the Hanok residence.

• Nuclear Engineering and Technology
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• v.54 no.9
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• pp.3205-3214
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• 2022

The aim of this study is to provide a clear and accessible method to obtain accurate true-stress strain data, and to extend the limited material data beyond the ultimate tensile strength (UTS) for AISI 304L. AISI 304L is used for the outer construction for some types of nuclear transport packages, due to its post-yield ductility and high failure strain. Material data for AISI 304L beyond UTS is limited throughout literature. 3D digital image correlation (DIC) was used during a series of uniaxial tensile experiments. Direct method extracted data such as true strain and instantaneous cross-sectional area throughout testing such that the true stress-strain response of the material up to failure could be created. Post processing of the DIC data has a considerable effect on the accuracy of the true stress-strain data produced. Influence of subset size and smoothing of data was investigated by using finite element analysis to inverse model the force displacement response in order to determine the true stress strain curve. The FE force displacement response was iteratively adapted, using subset size and smoothing of the DIC data. Results were validated by matching the force displacement response for the FE model and the experimental force displacement curve.

• Transactions of Materials Processing
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• v.28 no.6
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• pp.368-374
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• 2019

The past recent years have seen an increasing use of high-strength steel sheets in the automotive industry. However, the formability and damage prediction of these materials requires accurate acquisition of necking and fracture strains. Digital image correlation (DIC) is used to accurately capture the necking and fracture strains during testing. The fact that single time points of capturing vary with frame rate makes the need for an investigation necessary. For the high-strength steel DP980, the frame-rate dependences of the final necking and fracture strains values are analyzed here. To eliminate the influence of gauge length, the strains were measured locally by DIC. Results for three specimen shapes obtained with frame rates of 1 and 900 fps (frames per second) were considered and based on them, triaxiality failure diagrams (TFD) are established. It was observed that after diffuse necking, the deformation path departed from the initially linear one, and the stress triaxiality grew with ongoing deformation. It was further revealed that the frame rate-dependence of the necking strain was rather low (< 2%), whereas the fracture strain could be underestimated by up to 8% when the lower frame rate of 1 fps was used (compared with 900 fps). In this study, this issue is investigated while taking into consideration the three different triaxialities. These results demonstrate the importance of choosing an appropriate frame rate for the determination of necking and fracture strains in particular.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.39-46
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• 2022

As the limit state design method is applied as the design method of reinforced concrete structure, the ultimate state is considered when analyses or designing. In fact, when the reinforced concrete member is bent, there is a confining effect by stirrup, but the material curve of unconfined concretes applied when designing. In this study, to evaluate the suitability of the confined concrete model for flexural members, a 4-point bending test was conducted on RC simple beam with a double-reinforced rectangular cross-section, and the behavior of the member after yield was analyzed in detail using image processing method. For detailed analysis, the DIC method was adopted as an image analysis method, and the validity of DIC method was verified by comparing the measurement results with the LVDT. The distribution of the strain on the concrete surface calculated as a result of the DIC method could be obtained, and the average strain distribution of the cross-section was calculated. Using the average strain distribution, the stress distribution applied existing confined concrete model as a material curve could be derived. Through the comparison of the experimental results and the existing model application results, the suitability of the confined concrete model for RC flexural members having a rectangular cross-section was evaluated.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.1
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• pp.218-223
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• 2005

According to the Chinese and Korean medicinal and herbal literature, SSG(Silsosangami) is effective for the treatment of inflammation, hyperlipemia and arteriosclerosis. The pharmacological action of SSG has been limitedly studied in regard to ischemic infarction. This herbal medicine has been shown to express diverse activities such as immunomodulating, anti-infarction, anti-allergic and anti-inflammatory effects. Antisclerotic effects of SSG in experimentally induced atherosclerosis in rabbits have also been reported. However, pharmacological mechanisms of SSG on lipid metabolism and atherosclerosis formation are poorly understood. The present paper reports the effect of extracts obtained from SSG on endotoxin-induced experimental DIC in rats. Also, these were tested for their effect on endotoxin-induced blood platelet aggregation, thrombin-induced conversion of fibrinogen and fibrinolysis in vitro experiments with aspirin as a positive agent. The anti-thrombic properties of SSG were also investigated by means of analytical parameters of bood composition. The extracts of SSG and its seven herbs, except Cnidii Rhizoma and Carthami Flos, inhibited the endotoxin-induced DIC and thrombosis in rats. Also the extract inhibited the endotoxin-induced decrease in blood platelets and fibrinogen, and endotoxin-induced increase in fibrin degradation products (FDP) on disseminated intravascular coagulation in normal rats.

• Proceedings of the PSK Conference
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• 2000.04a
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• pp.107.2-107.2
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• 2000