• 제목/요약/키워드: Exact test

검색결과 1,479건 처리시간 0.026초

참치 기름담금 통조림의 $F_0$-값 설정에 관한 연구 (Establishment of $F_0$-value Criterion for Canned Tuna in Cottonseed Oil)

  • 한봉호;조현덕;유홍식;김상호;정윤수
    • 한국수산과학회지
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    • 제27권6호
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    • pp.675-681
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    • 1994
  • 통조림 식품의 가열살균 공정은 에너지 소비와 제품의 미생물학적 안전성, 영양적 및 기호적 품질을 감안하여 최적화되어야 한다. 본 연구에서는 일차적으로 가열살균에 따른 에너지 소비와 제품의 미생물학적 안전성과의 관계를 최적화하고자 하였다. 참치 기름담금 통조림을 서로 다른 살균조건 즉, $F_0$-값을 달리하여 열처리하고, 마이크로 컴퓨터를 이용하여 자체 개발한 $F_0$-값 측정 씨스템을 사용하여 측정한 $F_0$-값과 미생물학적 안전성과의 관계를 조사하여 적정 $F_0$-값을 제시하였다. 참치 기름담금 통조림의 냉점은 시험대상 통조림의 기하학적 중심이 아니라 내용물의 무게 중심이었으며, 시험대상 통조림들을 레토르트에 무작위하게 넣는 경우에 레토르트 내의 통조림의 위치는 F0-값에 영향을 미치지 않았다. 또한 미생물에 의한 원료의 오염방지를 위하여서는 가열살균 이전의 공정을 가능한 한 단축시켜야 함을 확인하였다. 원료 및 자숙한 참치에서 분리된 내열성 박테리아는 S. subtilis, B. cereus 및 B. pasteurii였고 이 중 내열성이 가장 큰 것은 B. subtilis였으나, $F^0$-값 6분 이상의 제품에서는 저장 중에도 미생물이 전혀 검출되지 않았으며, 상업적 살균에 의해 생산되는 참치 기름담금 통조림의 가열살균 기준으로는 $F_0$-값 6분이 적당한 것으로 판단되었다.

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일부 특수학교 장애인의 구강보건의식행태에 관한 조사연구 (Study on the oral health awareness and behavior in the special school for students of disability)

  • 송윤신;장우성
    • 한국치위생학회지
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    • 제11권1호
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    • pp.103-111
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    • 2011
  • Objectives : This study of oral health problems was conducted to 311 students in Special Schools in order to inquire into the state of their oral health behaviors, to find out the main obstacles against dental services, to secure dental reasonable basis for oral health promotion. Methods : A questionnaire survey was conducted in the Special School of the 311 students in the area of the metropolitan Seoul. By means of Chi-squared test and Fisher's exact test, oral hygiene habits for each type of the subjects, the contents of dental care services, the prerequisites to improve oral health, were inquired. To evaluate the effects to the current oral health status of types of disability, 2-way ANOVA was practiced. Results : The handicapped with Visual impairment, mental retardation, multiplicity with disabilities, answered negatively in their own oral health status. 47.4% of the deaf can do brush for theirselves without the inconvenience, but in other types of disability they showed that they were helped by others. Subjects did not use the secondary oral hygiene necessaries because, except brain damage, almost of types of disability impeded the convenient use. 60 to 88.2 percent of the total respondents were the recent visitors to dental clinique within 1 year, and the most common motives of the visiting dentist, is a routine medical examination, their movements to the dentist in all types of disabilities, needed helps of others. Most of them received medical treatment at a private dentist, the handicapped preferred the private care and place(49.8%). Only in the case of the brain disorders, extremely much of the disabled answered that they were needed the preventive treatment, and the another cases of disability were largely needed the treatment of the decayed teeth. To improve the oral health of the people with disabilities, at the opening of the clinics and hospitals over a certain size, the mandatory medical facilities for the care of the disabled should be preceded and followed by the improvement of dental insurance system so as to reduce the burdens of the cost of dental care. Conclusions : The improvement of oral health policy for the disabled are needed inevitably: Development of secondary oral hygienic easy to use for the disabled, the building systems of medical dental hospital with the disabled facilities, by the improvement of the insurance system, the reduction of the burden of payments.

영어캠프에서 원어민과 비원어민 교수의 수업운영에 대한 대학생들의 인식 연구 (University Students' Perceptions of NESTs' and NNESTs' Class Management in English Conversation Classes of an English Camp)

  • 방준
    • 한국콘텐츠학회논문지
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    • 제17권4호
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    • pp.72-82
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    • 2017
  • 본 연구의 목적은 원어민과 비원어민 교수가 함께 진행한 영어캠프에서의 수업과 수업운영에 대한 대학생들의 인식 차이에 대해 고찰하는 것이다. 연구 목적을 달성하기 위해 A 대학교 캠프에 참가한 남 녀 대학생 172명을 대상으로 캠프 만족도, 두 교수들에 대한 일반적 교수 자질, 수업 운영, 수업 내용 등에 대해 설문을 실시하였다. 원어민과 비원어민 교수가 진행한 캠프 수업과 수업운영에 대한 학생들의 인식 차이를 알아보기 위해 빈도분석 및 카이제곱 검증을 통해 설문자료를 분석하였다. 그 결과, 캠프에 참가한 대부분의 학생들은 원어민과 비원어민 교수가 함께 수업한 캠프에 대해 만족하였지만, 원어민과 비원어민 교수들의 교수자질, 수업 운영, 수업 내용에 대한 인식에는 차이가 있었다. 먼저, 학생들은 원어민 교수들이 수업을 흥미롭게 진행했다고 인식한 반면에 비원어민 교수들은 체계적으로 수업을 준비하고 운영한 것으로 인식하였다. 또한, 학생들은 원어민 교수들이 즉흥적으로 수업을 진행한 반면에 비원어민 교수들은 교재에 의존하며 더 많은 부교재를 제공한 것으로 인식하였다. 마지막으로 학생들은 비원어민 교수들이 원어민 교수에 비해 스피킹과 문법에 더 초점을 맞추어서 수업을 진행하였고, 과제, 시험, 피드백을 더 많이 제공하였고, 학생들과 의사소통을 더 원활하게 한 것으로 인식하였다. 이러한 결과를 바탕으로 본 연구는 원어민과 비원어민 교수들의 효과적인 수업을 위한 교육적인 제언을 하고자 한다.

Comparison of Efficacy and Toxicity of First Line Chemotherapy with or without Epirubicin for Patients with Advanced Stage Soft Tissue Sarcoma

  • Cao, Jie;Huang, Xin-En;Liu, Jin;Wu, Xue-Yan;Lu, Yan-Yan
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7171-7177
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    • 2013
  • Purpose: To compare the safety and efficacy of first-line chemotherapy regimen with or without doxorubicin in treating patients with advanced soft tissue sarcoma (STS). Patients and Methods: We retrospectively analyzed a cohort of 56 patients histologically confirmed with STS who were treated at Jiangsu Cancer Hospital and Research Institute from July 2011 to June 2012.The basic element of first line chemotherapy contained epirubicin in group B and lacked epirubicin in group A. Response was assessed using RECIST criteria. The Kaplan-Meier method was used to estimate progress free survival (PFS). Results: According to RECIST criteria, patients in group treated by chemotherapy without epirubicin, the objective response (OR) ratio was 6.5 % (CR0%+PR6.5%). Disease control rate (DCR=CR+PR+SD) was 25.8% with a median follow-up of 14.6 months, including 2 patients achieving a partial response (PR 6.5%) and a stable response (SD 19.4%) in 6. In group B with epirubicin based regimens, no patient had complete response, PR (28 %) was observed in 7 and SD (24 %) in 6. DCR was observed in 13 patients (52%). By Fisher's exact test, the DCR difference between the two groups was statistically significant (p=0.046). In group A, median PFS was 3.0 months (95%CI:2.1-3.8), compared with 4.0 months (95% CI:3.03-4.97) in group B (p=0.0397 by log-rank test). Epirubicin based chemotherapy and ECOG performance status 0-1 were identified as favorable factors for progression in our cohort of patients. Differences of nonhematologic and hematologic toxicities were not statistically significant between the two groups, and the addition of epirobicin was not associated with cardiac toxicity (p=0.446). Conclusion: Our study demonstrates that epirubicin-based chemotherapy is effective and well tolerated, and is superior to chemotherapy without epirubicin regarding efficacy. Therefore it is recommended that epirubicin-based chemotherapy should be considered as first line for patients with advanced STS.

요골두아탈구 환자에서 방사선 검사 시행과 연관된 인자 분석 (Factors Associated with Radiologic Tests in Patients with Radial Head Subluxation)

  • 장익완;김도균;박소영;서동범;정재윤;곽영호
    • Journal of Trauma and Injury
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    • 제27권2호
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    • pp.13-19
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    • 2014
  • Purpose: In general, X-ray examinations are not recommended for radial head subluxation (pulled elbow) patients. The purpose of this study was to determine the frequency of X-ray examinations and to investigate the factors associated with the decision to perform an X-ray examination on a patient with a pulled elbow. Methods: Patients who visited the pediatric emergency department (ED) of one tertiary hospital from January 1, 2011, to December 31, 2012, with a diagnosis of radial head subluxation at discharge were enrolled in this study. Through retrospective chart reviews, factors that could have influenced the decision to perform an X-ray examination and their statistical relevance were analyzed. Results: A total 308 patients were enrolled, and 101 patients (32.8%) underwent X-ray examinations. Among the 252 patients with a typical pulled elbow, 65 underwent X-ray examination. This result showed statistical significance compared to atypical pull-elbow group (25.8% vs. 64.3%, p<0.001). Factors associated with the decision to perform an X-ray examination were analyzed using the Chi-square test and the Fisher's exact test. The mechanism of injury and consultation with an orthopedic surgeon (p=0.001) showed statistical significance. In the multivariable logistic regression, the odds ratio (OR) for the injury mechanism was 4.7 (95% CI: 1.8~8.8, p<0.001) and that for consultation with an orthopedic surgeon was 8.0 (95% CI: 1.6~40.7, p=0.004). Conclusion: One third of patients with a pulled elbow underwent X-ray examination, and patients with an atypical mechanism of injury underwent more frequent X-ray examinations than did patients with a typical mechanism of injury. The factors that could have influenced the decision to perform an X-ray examination were mechanism of injury and consultation with an orthopedic surgeon.

정신 지체아 부모의 스트레스, 대응 및 적응 비교 (A Comparison Study of Stress, Coping and Adaptation between Fathers and Mothers of Mentally Retarded Children)

  • 문영임;구현영
    • 대한간호학회지
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    • 제26권1호
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    • pp.165-176
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    • 1996
  • The purpose of this study was to contribute to family nursing in the areas of reducing stress and improving coping for parents of mentally retarded children. Data were collected through self-report questionnaires during a period of 2 months between November 1994 and January 1995 in the Kyoung-in area. The subjects consist of 176 parents (88 mothers and 88 fathers) of mentally retarded children attending schools for the handicapped. The levels of general stress and of parental role stress were measured with the General stress scale and the Parental role stress scale, respectively. The coping scale developed by Folkman & LaZarus was adopted to measure the level of coping, and the patterns of adaptation scale developed by Damrosch & Perry was adopted to measure the patterns of adaptation. The data were analyzed by a SAS program using Fisher's exact test, paired t-test, and oneway ANOVA. The results are as follows ; 1. The level of general stress was significantly higher in mothers than in fathers. Mothers experienced a significantly greater level of parental role stress than fathers did. No significant difference in the level of coping was observed between mothers and fathers. There were differences in maternal and paternal patterns of adaptation. 2. The adaptation pattern of fathers was different according to their level of general stress, parental role stress and coping. The adaptation pattern of mothers was not different according to their level of general stress and parental role stress, but was according to their level of coping. 3. General stress experienced by fathers was different according to education, health status and support from their spouses. Satisfaction with family life, satisfaction with spouse and the support from spouse influenced coping used by fathers. Their level of parental role stress was not associated with any of their general characteristics. 4. In mothers, the level of general stress was different according to their health status, the level of parental role stress was related to satisfaction with family life and satisfaction with spouse. Their level of coping was associated with the sup port from spouse. The above findings indicate that mothers did not have more coping strategies than fathers did, despite the results which showed that mothers experienced greater stress than fathers did. Especially, the adaptation pattern of mothers was different according to their level of coping. Hence, nursing interventions directed at managing stress and improving coping should be used with mothers who use adaptation pattern 1. In particular, fathers should actively participate in parenting, and support their spouses.

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Association of Histopathological Markers with Clinico-Pathological Factors in Mexican Women with Breast Cancer

  • Bandala, Cindy;De la Garza-Montano, Paloma;Cortes-Algara, Alfredo;Cruz-Lopez, Jaime;Dominguez-Rubio, Rene;Gonzalez-Lopez, Nelly Judith;Cardenas-Rodriguez, Noemi;Alfaro-Rodriguez, A;Salcedo, M;Floriano-Sanchez, E;Lara-Padilla, Eleazar
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권18호
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    • pp.8397-8403
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    • 2016
  • Background: Breast cancer (BCa) is the most common malignancy in Mexican women. A set of histopathological markers has been established to guide BCa diagnosis, prognosis and treatment. Nevertheless, in only a few Mexican health services, such as that of the Secretariat of National Defense (SEDENA for its acronym in Spanish), are these markers commonly employed for assessing BCa. The aim of this study was to explore the association of Ki67, TP53, HER2/neu, estrogenic receptors (ERs) and progesterone receptors (PRs) with BCa risk factors. Materials and Methods: Clinical histories provided background patient information. Immunohistochemical (IHC) analysis was conducted on 48 tissue samples from women diagnosed with BCa and treated with radical mastectomy. The Chi square test or Fisher exact test together with the Pearson and Spearman correlation were applied. Results: On average, patients were $58{\pm}10.4$ years old. It was most common to find invasive ductal carcinoma (95.8%), histological grade 3 (45.8%), with a poor Nottingham Prognostic Index (NPI; 80.4%). ERs and PRs were associated with smoking and alcohol consumption, metastasis at diagnosis and Ki67 expression (p<0.05). PR+ was also related to urea and ER+ (p<0.05). Ki67 was associated with TP53 and elevated triglycerides (p<0.05), and HER2/neu with ER+, the number of pregnancies and tumor size (p<0.05). TP53 was also associated with a poor NPI (p<0.05) and CD34 with smoking (p<0.05). The triple negative status (ER-/PR-/HER2/neu-) was related to smoking, alcohol consumption, exposure to biomass, number of pregnancies, metastasis and a poor NPI (p<0.05). Moreover, the luminal B subty was associated with histological type (p=0.007), tumor size (p=0.03) and high cholesterol (p=0.02). Conclusions: Ki67, TP53, HER2/neu, ER and PR proved to be related to several clinical and pathological factors. Hence, it is crucial to determine this IHC profile in women at risk for BCa. Certain associations require further study to understand physiological/biochemical/molecular processes.

전국보건소 치과위생사의 노인의치보철사업 현황 및 전망 (The Present State and Prospect of Geriatric Denture Prosthetic Dentistry Affairs among Community Dental Hygienists)

  • 윤영숙;권양옥
    • 치위생과학회지
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    • 제6권4호
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    • pp.255-261
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    • 2006
  • 본 연구는 국민기초생활수급대상 65세 이상 노인들의 삶의질 향상과 구강건강을 유지, 증진 시키는데 필수적인 노인무료의치보철사업의 개선발전을 위하여 전국 각 구의 보건소 치과 위생사를 대상으로 노인무료의치보철사업의 현황을 파악하였으며 결과를 요약하면 아래와 같다. 현재 노인무료의치 보철사업의 홍보는 비교적 잘되고 있으며 대상자는 주로 동사무소에서 1년에 20~30명 정도를 선정하여 시행하고 있다. 대상치과는 47% 정도 치과의사협회와 연계하며, 주로 총의치를 많이 제작하고 있다. 제작 후 치과에 의존하고 있는 실정이라서 사후관리의 문제점이 많이 나타나고 있다. 또한 음식물섭취의 이로움과 무료시술이라는 점에서 64%의 높은 만족도를 얻고 있지만 의치장착 후 동통, 이물감 등으로 인해 불편함을 49%나 호소하는 것으로 나타났다. 이러한 결과를 토대로 노인의치보철사업의 문제점 및 만족도를 조사하여 향후 보다나은 노인 의료복지사업 중 하나인 노인무료의치보철사업의 앞으로 나아갈 방향에 대한 제언은 다음과 같다. 첫째, 의치 제작 후 지속적인 사후 관리가 이루어지기 위해서는 기초생활수급대상 노인들을 담당하는 방문 간호팀이나 사회복지사와 연계하여 의치 사용유무 및 관리상황 등을 점검하고, 의치관리법에 대한 교육이 시행되어야한다. 둘째, 의치가 가장 필요한 대상자에게 혜택이 주어질 수 있도록 대상자 선정 시 연령 기준이 하향 조정되어야하며, 보다 장기적인 대책으로 노인의치에 대한 보험급여화가 제기되어야한다. 셋째, 보다 양질의 무료의치보철사업을 수행하기 위해서는 환자의 구강 상태에 따른 정확한 수가 적용이 요구되며, 무엇보다도 무료의치보철사업을 시행하는 보건소 담당자와 치과의사의 봉사정신이 바탕이 되어야한다.

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농촌 건강증진 시범사업 지역주민과 비 시범사업 지역주민의 건강증진생활 행태 비교 (The Comparison with Health Promoting Life Styles of People between Demonstrating and Non-Demonstrating Health Promotion Services in Rural Community)

  • 이영숙
    • 농촌의학ㆍ지역보건
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    • 제34권1호
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    • pp.124-134
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    • 2009
  • 본 연구는 건강증진 시범사업을 수행하는 보건소와 자체 예산으로 건강증진 사업을 수행하는 보건소간 주민의 건강증진 생활 형태의 차이를 대표성있는 대상자를 선정하여 비교하고자 하였다. 대상은 지난 2004년 1년간 건강증진 시범사업 실시 지역 1개 군(H 군)과 비 실시 지역 1개 군(J 군)을 임의표집하고, 2개 군에 주소를 둔 20세 이상 주민 전체 중 연령별, 남녀별, 읍면별로 인구분포 수에 따라 층화비율 표집을 하여 총 1,300명을 추출하였다. 자료는 훈련받은 조사원이 젊은이는 자가보고식으로 노인은 면접법으로 수집하였고 도구는 한국판 BRFSS설문지를 수정보완하고, 보건복지부의 식생활자가점검표, 박순영이 개발한 스트레스 측정도구의 설문지를 이용하였으며, 두 지역 주민의 건강증진 생활행태를 차이를 x2-test와 Fisher's exact probability test로 비교하였다. 연구결과, 보건복지부 지원의 건강증진 시범사업지역 주민이 더 건강하다고 생각하고, 흡연율, 음주관련 생활행태가 모두 좋았으며 규칙적 운동율도 높았고, 스트레스도 유의하게 낮아 정부 지원건강증진 사업이 효과적이라고 나타났다. 이는 건강증진 5대 요소를 모두 포괄하는 사업계획을 하였으며, 타 보건소와의 경쟁을 통해 사업지역으로 선정되고, 사업 종료 후 내외부 평가 기준과 지침이 명확하며, 사업비 지원이 중요요인으로 작용하였다고 본다. 본 연구 결과를 토대로 다음과 같이 제언하고자한다. 1) 다년간 건강증진사업 시범지역과 비시범지역의 차이를 비교하는 반복연구가 필요하다. 2) 건강증진생활 행태를 중심으로 대도시, 도농복합도시 및 농촌의 건강증진 사업 효과를 비교할 필요가 있다.

광섬유 센서를 이용한 온도 및 변형 모니터링에 대한 현장응용 사례 (Case Studies on Distributed Temperature and Strain Sensing(DTSS) by using an Optical fiber)

  • 김중열;김유성;이성욱;민경주;박동수;방기성;김강식
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2006년도 춘계 학술발표회 논문집
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    • pp.86-95
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    • 2006
  • Brillouin backscatter is a type of reflection that occurs when light is shone into an optical fibre. Brillouin reflections are very sensitive to changes in the fibre arising from external effects, such as temperature, strain and pressure. We report here several case studies on the measurement of strain using Brillouin reflections. A mechanical bending test of an I beam, deployed with both fiber optic sensors and conventional strain gauge rosettes, was performed with the aim of evaluating: (1) the capability and technical limit of the DTSS technology for strain profile sensing; (2) the reliability of strain measurement using fiber optic sensor. The average values of strains obtained from both DTSS and strain gauges (corresponding to the deflection of I beam) showed a linear relationship and an excellent one-to-one match. A practical application of DTSS technology as an early warning system for land sliding or subsidence was examined through a field test at a hillside. Extremely strong, lightweight, rugged, survivable tight-buffered cables, designed for optimal strain transfer to the fibre, were used and clamped on the subsurface at a depth of about 50cm. It was proved that DTSS measurements could detect the exact position and the progress of strain changes induced by land sliding and subsidence. We also carried out the first ever distributed dynamic strain measurement (10Hz) on the Korean Train eXpress(KTX) railway track in Daejeon, Korea. The aim was to analyse the integrity of a section of track that had recently been repaired. The Sensornet DTSS was used to monitor this 85m section of track while a KTX train passed over. In the repaired section the strain increases to levels of 90 microstrain, whereas in the section of regular track the strain is in the region of 30-50 microstrain. The results were excellent since they demonstrate that the DTSS is able to measure small, dynamic changes in strain in rails during normal operating conditions. The current 10km range of the DTSS creates a potential to monitor the integrity of large lengths of track, and especially higher risk sections such as bridges, repaired track and areas at risk of subsidence.

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