• Title/Summary/Keyword: Evidence Based Diagnosis

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Material Diagnosis of Metalbased Pigments in Paintings Using Terahertz Imaging (테라헤르츠 이미징을 이용한 금속 성분 회화 재료 진단 연구)

  • Baek Nayeon;Lee Hanhyoung;Song Youna
    • Conservation Science in Museum
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    • v.29
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    • pp.111-132
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    • 2023
  • Terahertz radiation cannot pass through metal and therefore reflect and return most signals. Utilizing this property, this study analyzed information on paintings to verify the usage of metal materials on paintings and the scope of their application. First, the study tested specimens of metal-based pigments and synthetic pearl pigments with metallic colors and textures in order to compare basic characteristics of terahertz images, such as signal severance caused by metallic substances, traits reflected in cross-section images, and high degree of reflection. Subsequently, based on the collected information, the study diagnosed various types of paintings including Korean traditional paintings and oil paintings using the terahertz imaging technique to confirm the usage of metal-based pigments in the inner layers of paintings and their scope of application. The terahertz imaging technique could has the potential to provide scientific evidence for previously-undiscovered information and art-historical records about various types of paintings that used metalbased pigments, thereby rendering significant utility for the conservation and authentication of paintings.

A Human Case of Ballbladder Fascioliasis in Korea (담석을 동반한 담낭내 간질 감염 1례)

  • 홍성태;이순형
    • Parasites, Hosts and Diseases
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    • v.24 no.1
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    • pp.89-94
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    • 1986
  • The authors would record the fifth case of human fascioliasis in Korea, occurring in a 48 year old Korean man who lived in Munkyong, Kyongsangbuk-do. The diagnosis was based on the morphology and measurements of the eggs which were collected in necrotic debris from the tunnel-like ulcerations of the gallbladder wall which was surgically removed for a gall stone. Although we failed to find out the fluke in the specimen, there found an evidence of once presence of Fasciola in the inflamed wall of the gallbladder in this patient.

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Inflammation and hyponatremia: an underrecognized condition?

  • Park, Se Jin;Shin, Jae Il
    • Clinical and Experimental Pediatrics
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    • v.56 no.12
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    • pp.519-522
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    • 2013
  • Timely diagnosis of hyponatremia is important for preventing potential morbidity and mortality as it is often an indicator of underlying disease. The most common cause of eurvolemic hyponatremia is the syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Recent studies have demonstrated that proinflammatory cytokines such as interleukin (IL) $1{\beta}$ and IL-6 are involved in the development of hyponatremia, a condition that is associated with severe inflammation and is related to antidiuretic hormone (ADH) secretion. Serum sodium levels in hyponatremia are inversely correlated with the percentage of neutrophils, C-reactive protein, and N-terminal-pro brain type natriuretic peptide. Additionally, elevated levels of serum IL-6 and IL-$1{\beta}$ are found in inflammatory diseases, and their levels are higher in patients with hyponatremia. Because it is significantly correlated with the degree of inflammation in children, hyponatremia could be used as a diagnostic marker of pediatric inflammatory diseases. Based on available evidence, we hypothesize that hyponatremia may be associated with inflammatory diseases in general. Understanding the mechanisms responsible for augmented ADH secretion during inflammation, monitoring patient sodium levels, and selecting the appropriate intravenous fluid treatment are important components that may lower the morbidity and mortality of patients in a critical condition.

Prediction Model for Breast Cancer Diagnosis using Baysian Algorithm (베이지안 알고리즘을 이용한 유방암 진단 예측모델)

  • Jung, Yong-Gyu;Lee, Yeon-Joo;Won, Jae-Kang
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.12 no.2
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    • pp.175-180
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    • 2012
  • Currently datamining sector is interested and applied in many areas. In other words, datamining is predicting the future to discover hidden correlations and make decisions. To interpret data on various aspects can be converted to real expectation. Analyzing the results even a simple can be found big difference. The properties associated with breast cancer by about applying bayesian theory is used to predict the probability. In the past patient data, doctors may be obtaining by applying evidence-based care for patients with the results of examination and By using the the past patient data.

Analysis of Clinical Research Trends on Cold-Heat Pattern Identification in Korea - Focused on Quantitative Indicators for General People (한열변증의 국내 임상연구 동향 분석 - 일반인의 정량지표를 중심으로)

  • Yeo, Min Kyung;Lee, Young Seop
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.2
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    • pp.145-152
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    • 2017
  • The purpose of this study was to investigate the clinical research of Cold-Heat of pattern identification(PI) focused on quantitative indicators for general people in Korea, through the review of OASIS, KISS, DBpia, NDSL database. Ten clinical researches were analyzed in this study. These research gradually started from 2004 to 2009 but there was no research after 2010. Diagnosis of Cold-Heat PI all was done through a questionnaire, 7 or most researches had not used the intervention methods. Quantitative indicators related to the Cold-Heat PI mentioned in the selected 10 researches are seven, these indicators include heart rate variability(HRV), electroencephalogram, Yangdorak, respiratory index, electrogastrography, acoustic analysis index, western health test index. Related to the HRV were 3 researches, but correlation of significant indicators was a few levels(R=0.026-0.090). So far, studies regarding at the quantitative indicators of the prior the Cold-Heat PI were few, and the results of the study showed that low statistical precision, a lack of biological basis. Refer to the current state, in the future, we expect that research of quantitative indicators of scientific evidence-based through calculated and precise research concerning Cold-Heat PI be regarded as important in Korean Medicine.

Benign Osteopetrosis : Report of a Case (양성형 골화석증)

  • Kim Kyung-A;Lim Suk-Young;Koh Kwang-Joon
    • Imaging Science in Dentistry
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    • v.30 no.1
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    • pp.80-86
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    • 2000
  • A 37-year-old male with the complaint of intermittent gingival swelling and dull pain associated with the food impaction of the mandibular third molar area was referred to our department of Chonbuk National University Hospital. The dental history of the patient showed that he had extracted the maxillary left third molar without complications two years ago. Intraoral and panoramic radiographs showed diffuse increased radiopacity of the maxilla and mandible. The trabecular pattern was obliterated. Postero-anterior skull and lateral skull radiographs showed thickening of cortical bone and diffuse increased radiopacity of the skull. Additional radiographs showed similar changes in the lumbar spine, clavicles, iliac bone and femur. However, no evidence of osteomyelitis was observed clinically and radiographically. Laboratory findings showed normal values of serum calcium, phosphorus, and alkaline phosphatase. Based on the radiographic examinations and the laboratory findings, final diagnosis was made as a benign osteopetrosis.

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PCR-Based Detection of Mycoplasma Species

  • Sung Hyeran;Kang Seung Hye;Bae Yoon Jin;Hong Jin Tae;Chung Youn Bok;Lee Chong-Kil;Song Sukgil
    • Journal of Microbiology
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    • v.44 no.1
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    • pp.42-49
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    • 2006
  • In this study, we describe our newly-developed sensitive two-stage PCR procedure for the detection of 13 common mycoplasmal contaminants (M. arthritidis, M. bovis, M. fermentans, M. genitalium, M. hominis, M. hyorhinis, M. neurolyticum, M. orale, M. pirum, M. pneumoniae, M. pulmonis, M. salivarium, U. urealyticum). For primary amplification, the DNA regions encompassing the 16S and 23S rRNA genes of 13 species were targeted using general mycoplasma primers. The primary PCR products were then subjected to secondary nested PCR, using two different primer pair sets, designed via the multiple alignment of nucleotide sequences obtained from the 13 mycoplasmal species. The nested PCR, which generated DNA fragments of 165-353 bp, was found to be able to detect 1-2 copies of the target DNA, and evidenced no cross-reactivity with the generated DNA of related microorganisms or of human cell lines, thereby confirming the sensitivity and specificity of the primers used. The identification of contaminated species was' achieved via the performance of restriction fragment length polymorphism (RFLP) coupled with Sau3AI digestion. The results obtained in this study furnish evidence suggesting that the employed assay system constitutes an effective tool for the disagnosis of mycoplasmal contamination in cell culture systems.

The Value and Limitations of Guidelines, Expert Consensus, and Registries on the Management of Patients with Thoracic Aortic Disease

  • Pacini, Davide;Murana, Giacomo;Leone, Alessandro;Marco, Luca Di;Pantaleo, Antonio
    • Journal of Chest Surgery
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    • v.49 no.6
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    • pp.413-420
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    • 2016
  • Doctors are often faced with difficult decisions and uncertainty when patients need a certain treatment. They routinely rely on the scientific literature, in addition to their knowledge, experience, and patient preferences. Clinical practice guidelines are created with the intention of facilitating decision-making. They may offer concise instructions for the diagnosis, management (medical or surgical treatments), and prevention of specific diseases or conditions. All information included in the final version are the result of a systematic review of scientific articles and an assessment of the benefits and costs of alternative care options. The final document attempts to meet the needs of most patients in most circumstances and clinicians, aware of these recommendations, should always make individualized treatment decisions. In this review, we attempted to define the intent and applicability of clinical practice guidelines, expert consensus documents, and registry studies, focusing on the management of patients with thoracic aortic disease.

Robotic Surgery in Cancer Care: Opportunities and Challenges

  • Mohammadzadeh, Niloofar;Safdari, Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.3
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    • pp.1081-1083
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    • 2014
  • Malignancy-associated mortality, decreased productivity, and spiritual, social and physical burden in cancer patients and their families impose heavy costs on communities. Therefore cancer prevention, early detection, rapid diagnosis and timely treatment are very important. Use of modern methods based on information technology in cancer can improve patient survival and increase patient and health care provider satisfaction. Robot technology is used in different areas of health care and applications in surgery have emerged affecting the cancer treatment domain. Computerized and robotic devices can offer enhanced dexterity by tremor abolition, motion scaling, high quality 3D vision for surgeons and decreased blood loss, significant reduction in narcotic use, and reduced hospital stay for patients. However, there are many challenges like lack of surgical community support, large size, high costs and absence of tactile and haptic feedback. A comprehensive view to identify all factors in different aspects such as technical, legal and ethical items that prevent robotic surgery adoption is thus very necessary. Also evidence must be presented to surgeons to achieve appropriate support from physicians. The aim of this review article is to survey applications, opportunities and barriers to this advanced technology in patients and surgeons as an approach to improve cancer care.

Development of Classification Model for Healthcare Contents on the Online Community (온라인 커뮤니티에서의 건강 관련 콘텐츠 분류 모형 개발)

  • Kim, Tae-Yun;Kim, Yoo-Sin;Choi, Sang-Hyun;Kim, Do-Hun;Chang, You-Jin
    • The Journal of Information Systems
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    • v.26 no.4
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    • pp.285-301
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    • 2017
  • Purpose In this paper we verified the reliabilities of healthcare-related information provided by various users on the site of Naver Jisikin, a Korean typical search platform. Based on Q&A contents we validated answers' reliabilities to the asked questions about a lung cancer with the help of professors at a medical school. Design/methodology/approach The content analysis includes that the types of questions are classified into symptom/diagnosis, therapy, prognosis, after-management and so on. The answers contains advice, advertisement, oriental medicine, and religion as well as the above 5 question categories. The validation results of medical evidence about each answer show that only 49% among all answers have medical grounds. Findings We classified the medical grounded answers into three levels; high, medium and low. Among all answers we need to find out the answers including advertisement because the answers can be harmful to patients. We found the method to select the answers containing advertisement contents with the help of text mining research. The selection model presents high performance as 84% classification accuracy.