• Clinical Psychopharmacology and Neuroscience
• /
• 제16권4호
• /
• pp.361-375
• /
• 2018

We aimed to compare the efficacy and safety of long-acting injectable (LAI) and oral second-generation antipsychotics (SGAs) in treating schizophrenia by performing a systematic review and meta-analysis. MEDLINE, EMBASE, PsycINFO, CINAHL, and the Cochrane Library, as well as five Korean databases, were systemically searched to identify studies published from 2000 to 16 April 2015, which compared the efficacy and safety of LAI and oral SGAs. Using data from randomized controlled trials (RCTs), meta-analyses were conducted. In addition, the GRADE (the Grading of Recommendations, Assessment, Development and Evaluation) approach was applied to explicitly assess the quality of the evidence. A total of 30 studies including 17 RCTs and 13 observational studies were selected. The group treated with LAI SGAs was characterized by significantly lower relapse rates, longer times to relapse and fewer hospital days, but also by a higher occurrence of extrapyramidal syndrome and prolactin-related symptoms than that in the group treated with oral SGAs. Our findings demonstrate that there is moderate to high level of evidence suggesting that in the treatment of schizophrenia, LAI SGAs have higher efficacy and are associated with higher rates of extrapyramidal syndrome and prolactin-related symptoms. Additionally, the use of LAI SGAs should be combined with appropriate measures to reduce dopamine $D_2$ antagonism-related symptoms.

• 대한통합의학회지
• /
• 제11권2호
• /
• pp.231-242
• /
• 2023

Purpose : This study aimed to identify ways to improve the quality of physical therapy research and ultimately review the current situation to improve evidence-based decision-making in physical therapy. Methods : For better evidence-based decision-making in physical therapy, researchers should review the quality assessment of articles in more detail and report their findings for valid and appropriate level of evidence and strength of recommendations. The level of evidence affects how well the findings are derived from well-designed literature. The evaluation of the evidence focuses primarily on the study design and the degree of bias that may compromise the validity of the findings. The final recommendation is based on a combination of the study design and literature quality. To uncover gems of information in each paper, a risk of bias assessment should be performed after the literature has been initially selected. Results : Researchers should consider the complexity of the intervention, appropriate grouping, and calculation of effect sizes for the intervention. Researchers conducting systematic reviews should provide a detailed description of the quality assessment performed and present a detailed analysis of their interpretation of the results. The results of systematic reviews and meta-analyses should be interpreted with caution and include a risk of bias assessment. Guidelines for the level of evidence and strength of recommendations should be developed and utilized more broadly to improve reporting practices in physical therapy. Conclusion : Researchers should be knowledgeable about the strengths and limitations of each study design and methodology. In the future, researchers will also need to improve their ability to critically evaluate their findings, given the potential for their results to influence clinical practice.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권10호
• /
• pp.5325-5325
• /
• 2012

• 한국식품조리과학회지
• /
• 제25권2호
• /
• pp.206-218
• /
• 2009

The study assessed the relationship between brand evidence (e.g., brand name, price/value for money, servicescape, core service, employee service and self-image congruence) and positive/negative emotion and brand satisfaction, and between positive/negative emotion and brand satisfaction in the family restaurant setting. Also, the relationship of positive/negative emotion and brand satisfaction with customer loyalty were assessed. Customers who used five brands of family restaurant in Daegu and Pusan during October of 2008 were surveyed by questionnaires. Brand evidence was positively related to positive emotion and brand satisfaction, and was negatively related to negative emotion. Positive emotion was positively related to brand satisfaction and negative emotion was negatively related to brand satisfaction. Brand satisfaction was positively relatively to customer loyalty. The results indicate that management of family restaurants should focus on brand evidence as a means of increasing profits and sales volume.

• 한국콘텐츠학회논문지
• /
• 제6권5호
• /
• pp.153-160
• /
• 2006

디지털 영상매체와 관련된 과학적 기술이 빠르게 진보함에 따라 경찰수사 활동에도 디지털 영상장비의 활용이 보편화되고 있는 추세이다. 그러나, 디지털 영상자료는 종전의 필름방식 사진에 비해 위 변조의 가능성이 높기 때문에 법정에서 확실한 증거로 채택되지 못 할 우려가 있다. 그러므로 본 논문에서는 외국 법정에서 디지털 영상의 지위를 고찰하고 이와 관련하여 우리나라에서 경찰 수사활동시 예상되는 문제점을 검토함으로써 적절한 대응방안을 제시하고자 한다.

• 대한전기학회논문지:전력기술부문A
• /
• 제48권10호
• /
• pp.1335-1343
• /
• 1999

This paper presents concrete pattern recognition method to identify the strength of concrete by evidence accumulation with multiple parameters based on artificial intelligence techniques. At first, zero-crossing(ZCR), mean frequency(MEANF), median frequency(MEDF) and autoregressive model coefficient(ARC) are extracted as feature parameters from ultrasonic signal of concrete. Pattern recognition is carried out through the evidence accumulation procedure using distance measured with reference parameters. A fuzzy mapping function is designed to transform the distances for the application of the evidence accumulation method. Results are presented to support the feasibility of the suggested approach for concrete pattern recognition.

• Ocean and Polar Research
• /
• 제25권4호
• /
• pp.633-644
• /
• 2003

The distribution and abundance of Antarctic krill (Euphausia superba), particularly in the South Atlantic, has traditionally been viewed as primarily determined by the flow of the Antarctic Circumpolar Current. Krill are viewed as being particles on a conveyor belt that carries them around the Antarctic continent resulting in a single circumpolar population. The evidence to support this viewpoint is largely circumstantial and there is very little direct evidence available of krill being moved by the currents-krill flux. There is also considerable biological and physical evidence which suggests that other factors may play a dominant role in the life history and distribution of krill. This review examines the evidence fur krill flux and also examines evidence that does not accord with this theory. The management implications of assuming krill flux are outlined and some lines for future research are suggested.

• 한국중재학회지:중재연구
• /
• 제23권4호
• /
• pp.77-96
• /
• 2013

International Arbitration has distinguished itself as a method for dispute resolution that pleases both common and civil law practitioners. It, however, is not free of criticism, especially when fact-finding and evidentiary issues are at play. Perhaps because fact-finding is very closely linked to the culture in which they lie, perhaps because of the lack of a clear evidentiary rules governing international arbitration, a theory of evidence in international arbitration is still far fetched. Through the analysis of the distinctions between dispute resolution systems and the search for truth paradigm, this paper aims to develop and present an outline for the development of a theory of evidence in international arbitration.

• 한국임상약학회지
• /
• 제23권3호
• /
• pp.185-196
• /
• 2013

This study aims to explore the difficulties of evidence-based pharmaceutical policy-making in the Korean context where several pharmaceutical policies were introduced within a short period. Semi-structured in-depth interviews were performed with eight experts in the Korean pharmaceutical arena. The key challenge in Korean situation might be the apparent lack of available evidence caused by the limited resources, the lack of policy consistency and coordination ability in the authorities and distrust across stakeholders. To build an evidence-based tradition, it is essential to resolve the tangible lack. At once, more fundamental changes seem to be required in the intangible policy environments.

• Journal of information and communication convergence engineering
• /
• 제13권2호
• /
• pp.74-80
• /
• 2015

In cognitive radios, spectrum sensing plays an important role in accurately detecting the presence or absence of a licensed user. However, the intervention of malicious users (MUs) degrades the performance of spectrum sensing. Such users manipulate the local results and send falsified data to the data fusion center; this process is called spectrum sensing data falsification (SSDF). Thus, MUs degrade the spectrum sensing performance and increase uncertainty issues. In this paper, we propose a method based on the Hausdorff distance and a similarity measure matrix to measure the difference between the normal user evidence and the malicious user evidence. In addition, we use the Dempster-Shafer theory to combine the sets of evidence from each normal user evidence. We compare the proposed method with the k-means and Jaccard distance methods for malicious user detection. Simulation results show that the proposed method is effective against an SSDF attack.