• Title/Summary/Keyword: Event duration

Search Result 305, Processing Time 0.03 seconds

Photodynamic Action by Endogenous Non-Chlorophyll Sensitizer As a Cause of Photoinhibition

  • Suh, Hwa-Jin;Kim, Chang-Sook;Jin Jung
    • Journal of Photoscience
    • /
    • v.7 no.3
    • /
    • pp.87-95
    • /
    • 2000
  • As sunlight not always optimized for every terrestrial plant in terms of light quality, quantity and duration, some plants suffer detrimental effects of sunlight exposure under certain conditions. Photoinhibition of photosynthesis is a typical phenomenon representing harmful light effects, commonly observed in many photosynthetic organisms. It is generally accepted that functional, structural loss of photosystem II complex(PSII) is the primary event of photoinhibition. Accumulating data also suggest that singlet oxygen($^1$O$_2$) is the main toxic species directly involved in it. There are two different views on the specific site and mechanism of $^1$O$_2$ production in the photosynthetic membrane. One of them favors the PSII reaction center, where the primary charge pairs recombination occurs as a prerequisite for the generation of $^1$O$_2$, and the other inclines to photosensitized $^1$O$_2$ formation by a substance located outside PSII. This article describes how we, as the advocators of the latter concept, have arrived at the conclusion that $^1$O$_2$ immediately involved in PSII photodamage is largely generated from the Rieske center of the cytochrome b$_{6}$/f complex and diffuses into PSII, attacking the reaction center subunits.s.

  • PDF

Automatic Detection Algorithm for Snoring and Heart beat Using a Single Piezoelectric Sensor (압전센서를 이용한 코골이와 심박 검출을 위한 자동 알고리즘)

  • Urtnasan, Erdenebayar;Park, Jong-Uk;Jeong, Pil-Soo;Lee, Kyoung-Joung
    • Journal of Biomedical Engineering Research
    • /
    • v.36 no.5
    • /
    • pp.143-149
    • /
    • 2015
  • In this paper, we proposed a novel method for automatic detection for snoring and heart beat using a single piezoelectric sensor. For this study multi-rate signal processing technique was applied to detect snoring and heart beat from the single source signal. The sound event duration and intensity features were used to snore detection and heart beat was found by autocorrelation. The performance of the proposed method was evaluated on clinical database, which is the nocturnal piezoelectric snoring data of 30 patients that suffered obstructive sleep apnea. The method achieved sensitivity of 88.6%, specificity of 96.1% with accuracy of 95.6% for snoring and sensitivity of 94.1% and positive predictive value of 87.6% for heart beat, respectively. These results suggest that the proposed method can be a useful tool in sleep monitoring and sleep disordered breathing diagnosis.

Numerical Analysis for Booster Effect in DME HCCI Engine with Fuel Stratification (연료의 불균질성을 갖는 DME HCCI엔진에서 과급의 효과에 관한 수치해석)

  • Kwon, O-Seok;Lim, Ock-Taeck
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.18 no.3
    • /
    • pp.19-25
    • /
    • 2010
  • The purpose of this study is to gain a better understanding of the effects of fuel stratification on reducing the pressure-rise rate at high load in HCCI combustion. It was found that fuel stratification offers good potential to achieve a staged combustion event and reduced pressure-rise rates. The engine is fueled with Di-Methyl Ether (DME) which has unique 2-stage heat release. Numerical analysis is conducted with single and multi-zones model and detailed chemical reaction scheme is done by chemkin and senkin. Calculation result shows that proper fuel stratification prolongs combustion duration and reduce pressure rise rate. Besides IMEP, combustion efficiency and indicated thermal efficiency keep constant. However, too wide fuel stratification increases pressure rise rate and CO and NOx emissions in exhaust gas.

Effect of Valve Lift and Timing on Internal Exhaust Gas Recirculation and Combustion in DME Homogeneous Charge Compression Ignition Engine (DME 예혼합 압축 착화 엔진에서 밸브 양정과 개폐시기가 내부 배기가스 재순환과 연소에 미치는 영향)

  • Jang, Jin-Young;Bae, Choong-Sik
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.17 no.4
    • /
    • pp.93-100
    • /
    • 2009
  • Intake/exhaust valve timing and exhaust cam lift were changed to control the internal exhaust gas recirculation (IEGR) and combustion phase of homogeneous charge compression ignition (HCCI) engine. To measure the IEGR rate, in-cylinder gas was sampled during from intake valve close to before ignition start. The lower exhaust cam made shorter valve event than higher exhaust cam and made IEGR increase because of trapping the exhaust gas. IEGR rate was more affected by exhaust valve timing than intake valve timing and increased as exhaust valve timing advanced. In-cylinder pressure was increased near top dead center due to early close of exhaust valve. Ignition timing was more affected by intake valve timing than exhaust valve timing in case of exhaust valve lift 8.4 mm, while ignition timing was affected by both intake and exhaust valve timing in case of exhaust valve 2.5 mm. Burn duration with exhaust valve lift 2.5 mm was longer than other case due to higher IEGR rate. The fuel conversion efficiency with higher exhaust valve lift was higher than that with lower exhaust valve lift. The late exhaust and intake maximum open point (MOP) made the fuel conversion efficiency improve.

Statistical study of phase reversal locations on the SC-associated preliminary impulse

  • Sung, Suk-Kyung;Kim, Khan-Hyuk;Cho, Kyung-Suk
    • Bulletin of the Korean Space Science Society
    • /
    • 2008.10a
    • /
    • pp.30.3-30.3
    • /
    • 2008
  • In this study, we investigate the magnetic latitude of phase reversal on the sudden commencement (SC)-associated preliminary impulse with 267 SC events using the ground magnetometer data of the IMAGE from 1997 to 2005. During SC event, geomagnetic fields are affected by various currents flowing in the magnetosphere and/or ionosphere. In particular, high-latitude geomagnetic field variations are significantly dominated by the change of SC-associated field aligned current (FAC). Until now, however, there are few studies to examine where the location of the FAC in the ionosphere is and what determines the location of the FAC. The location of the SC-associated FAC can be examined by using magnetometer data obtained from high-latitude stations distributed along the same magnetic meridian. The phase reversal locations are concentrated two regions, ~62 deg (L~4.5) and ~70 deg (L~8.5) in magnetic latitude. If FAC is a result of a mode conversion from fast mode to Alfven mode, then the FAC location could be determine by the duration time of the input energy. When we use the rise time, dT, as the input energy, there is no relationship between dT and the location where the first pulse of SC is reversed. We consider other factors such as local time and solar wind condition.

  • PDF

Prognostic factors and treatment of pediatric acute lymphoblastic leukemia

  • Lee, Jae Wook;Cho, Bin
    • Clinical and Experimental Pediatrics
    • /
    • v.60 no.5
    • /
    • pp.129-137
    • /
    • 2017
  • The event-free survival (EFS) for pediatric acute lymphoblastic leukemia (ALL) has shown remarkable improvement in the past several decades. In Korea also, a recent study showed 10-year EFS of 78.5%. Much of the improved outcome for pediatric ALL stems from the accurate identification of prognostic factors, the designation of risk group based on these factors, and treatment of appropriate duration and intensity according to risk group, done within the setting of cooperative clinical trials. The schema of first-line therapy for ALL remains mostly unchanged, although many groups have now reported on the elimination of cranial irradiation in all patients with low rates of central nervous system relapse. Specific high risk subgroups, such as Philadelphia chromosome-positive (Ph+) ALL and infant ALL continue to have significantly lower survival than other ALL patients. The introduction of tyrosine kinase inhibitors into therapy has led to enhanced outcome for Ph+ ALL patients. Infant ALL patients, particularly those with MLL rearrangements, continue to have poor outcome, despite treatment intensification including allogeneic hematopoietic cell transplantation. Relapsed ALL is a leading cause of mortality in pediatric cancer. Recent advances in immunotherapy targeting the CD19 of the ALL blast have shown remarkable efficacy in some of these relapsed and refractory patients. With improved survival, much of the current focus is on decreasing the long-term toxicities of treatment.

Low-power Routing Algorithm using Routing History Cache for Wireless Sensor Network (RHC(Routing History Cache)를 사용한 저전력 소모 라우팅 알고리즘)

  • Lee, Doo-Wan;Jang, Kyung-Sik
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.13 no.11
    • /
    • pp.2441-2446
    • /
    • 2009
  • Wireless Sensor Network collects a data from the specific area and the control is composed of small sensor nodes. Like this sensors to after that is established at the beginning are operated with the battery, the operational duration until several years must be continued from several months and will be able to apply the resources which is restricted in efficiently there must be. In this paper RHC (rounting history cache) applies in Directed Diffusion which apply a data central concept a reliability and an efficiency in data transfer course set. RHC algorithms which proposes each sensor node updated RHC of oneself with periodic and because storing the optimization course the course and, every event occurrence hour they reset the energy is wasted the fact that a reliability with minimization of duplication message improved.

Impact identification and localization using a sample-force-dictionary - General Theory and its applications to beam structures

  • Ginsberg, Daniel;Fritzen, Claus-Peter
    • Structural Monitoring and Maintenance
    • /
    • v.3 no.3
    • /
    • pp.195-214
    • /
    • 2016
  • Monitoring of impact loads is a very important technique in the field of structural health monitoring (SHM). However, in most cases it is not possible to measure impact events directly, so they need to be reconstructed. Impact load reconstruction refers to the problem of estimating an input to a dynamic system when the system output and the impulse response function are usually known. Generally this leads to a so called ill-posed inverse problem. It is reasonable to use prior knowledge of the force in order to develop more suitable reconstruction strategies and to increase accuracy. An impact event is characterized by a short time duration and a spatial concentration. Moreover the force time history of an impact has a specific shape, which also can be taken into account. In this contribution these properties of the external force are employed to create a sample-force-dictionary and thus to transform the ill-posed problem into a sparse recovery task. The sparse solution is acquired by solving a minimization problem known as basis pursuit denoising (BPDN). The reconstruction approach shown here is capable to estimate simultaneously the magnitude of the impact and the impact location, with a minimum number of accelerometers. The possibility of reconstructing the impact based on a noisy output signal is first demonstrated with simulated measurements of a simple beam structure. Then an experimental investigation of a real beam is performed.

Associations between Clinical Characteristics and Plasma BDNF Levels of Panic Disorder (공황장애의 임상적 특성과 Brain-Derived Neurotrophic Factor 농도와의 관계)

  • Hwang, In-Ho;Park, Jong-Il;Yang, Jong-Chul
    • Anxiety and mood
    • /
    • v.11 no.2
    • /
    • pp.129-135
    • /
    • 2015
  • Objective : Brain-derived neurotrophic factor (BDNF) is implicated in the pathophysiology of several neuropsychiatric disorders. However, there are few studies on BDNF of panic disorder. In this study, we investigated plasma BDNF levels in patients with panic disorder, and evaluated whether there are associations between clinical characteristics of panic disorder and plasma BDNF levels. Methods : We included 110 patients with panic disorder and 110 health controls in the current study. Plasma BDNF levels were measured by the enzyme-linked immunosorbent assay (ELISA). Plasma BDNF level differences were evaluated according to the clinical characteristics, such as duration of illness, recent stressful life event, agoraphobia, and insomnia. Results : The mean plasma BDNF levels of patients with panic disorder were significantly lower, as compared with those of controls (192.50 pg/mL vs. 693.75 pg/mL, t=8.838, p<0.001). The mean plasma BDNF levels of patients who had recent stressful life events were significantly higher, as compared with those who did not ($269.79{\pm}358.96pg/mL$ vs. $136.94{\pm}187.06pg/mL$, t=-2.525, p=0.013). Conclusion : These results suggested that BDNF plays a potential role in the pathophysiology of panic disorder.

Significance of Oligoclonal Bands after Stem Cell Transplantation in Multiple Myeloma Cases

  • Liu, Ai-Jun;Zong, Hong;Yang, Guang-Zhong;Zhai, Yu-Hua;Li, Li-Hong
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.4
    • /
    • pp.1483-1486
    • /
    • 2012
  • Objective: To determine the characteristics of oligoclonal bands that are frequently detected by serum protein electrophoresis (SPEP) and immunofixation electrophoresis (IFE) after stem cell transplantation. Methods: We retrospectively analyzed 56 patients with multiple myeloma (MM) undergoing transplantation, and standard immunofixation electrophoresis was used to identify and quantify paraproteins. Results: The median follow-up was 35 months (range, 10-76months) and 21 patients relapsed. Twelve (25.0%) demonstrated oligoclonal bands after a median time 1.4 months (range, 1-3months), with a median duration of 5.8 months (range, 1-15months). The majority patients with oligoclonal bands had normal quantities of immunoglobulins and the one year event free survival (EFS) was 92%, even higher than for patients without OBs (P=0.002). Conclusion: Oligoclonal bands frequent develop post-transplantation in MM cases. In the vast majority of patients, they may not represent relapsed disease, and more likely represent a transient phenomenon representing recovery of impaired immunoglobulin production.