• Proceedings of the Safety Management and Science Conference
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• 2004.11a
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• pp.165-170
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• 2004

It used the flow system of the stone polishing machine head and it developed a multi axis whetstone polishing system. With the result, the defect by line contact polishing does not occur in both ends of the stone, and it came to trim smoothly. As the index of the surface roughness decreased to 3.6 times, the polishing effect improved greatly. It decreased greatly the dust and a noise with the wet polishing, and the factors of the duty evasion at production site were solved with the work environment improvement against the polishing process of the stone industry and work intensive reduction.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.30 no.4
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• pp.54-61
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• 2007

This research relates to the patent application tendency about the components and modules of the intelligent robot among the robotics industry in which the market is more and more expanded. The patent about the components and modules of intelligent robot was analyzed from not only Korea but also U.S, Japanese and Europe which is called as the 3 pole of patent. By this research the government which supervises the nation's research policy can obtain the objective information of the industrial tendency, so it can establish the investment policy of national research and development. And the researchers can set up the research direction for evasion from patent infringement trouble by obtaining the patent application information. This also shows whether their research can be competitive or not.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.30 no.4
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• pp.46-53
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• 2007

This research relates to the patent application tendency about the hardware platform of the intelligent robot among the robotics industry in which the market is more and more expanded. The patent about the hardware field of intelligent robot was analyzed from not only Korea but also U.S., Japanese and Europe which is called as the 3 pole of patent. By this research the government which supervises the nation's research policy can obtain the objective information of the industrial tendency, so it can establish the investment policy of national research and development. And the researchers can set up the research direction for evasion from patent infringement trouble by obtaining the patent application information. This also shows whether their research can be competitive or not.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.04a
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• pp.468-470
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• 2015

ActiveX가 법규제로 인해 없어지고 새로운 간편 절제 시스템이 출시되고 있다. 새롭게 도입되는 간편 결제 시스템의 경우 사용자가 한 번 내려 받으면 인터넷 익스플로러뿐만 아니라 사파리나 크롬 등 다른 브라우저를 사용 시 따로 보안프로그램을 내려 받지 않아도 된다고 한다. ActiveX대신 새로운 결제 시스템의 'exe'방식의 프로그램은 한 번 내려 받아 영구 사용할 수 있으며, 이러한 'exe' 프로그램은 인증우회가 가능하여 해커가 제3자의 금융정보를 가지게 된다면 간단한 우회를 통한 공격이 가능할 것으로 예측된다. 본 논문에서는 이러한 인증우회 공격에 관한 시나리오 및 'exe'프로그램 내부의 보안프로그램에서의 이상 징후 조기 탐지를 이용한 사전 예방기법을 제안한다.

• Journal of Cancer Prevention
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• v.22 no.4
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• pp.203-210
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• 2017

After transcription, RNAs are always associated with RNA binding proteins (RBPs) to perform biological activities. RBPs can interact with target RNAs in sequence- and structure-dependent manner through their unique RNA binding domains. In development and progression of carcinogenesis, RBPs are aberrantly dysregulated in many human cancers with various mechanisms, such as genetic alteration, epigenetic change, noncoding RNA-mediated regulation, and post-translational modifications. Upon deregulation in cancers, RBPs influence every step in the development and progression of cancer, including sustained cell proliferation, evasion of apoptosis, avoiding immune surveillance, inducing angiogenesis, and activating metastasis. To develop therapeutic strategies targeting RBPs, RNA interference-based oligonucleotides or small molecule inhibitors have been screened based on reduced RBP-RNA interaction and changed level of target RNAs. Identification of binding RNAs with high-throughput techniques and integral analysis of multiple datasets will help us develop new therapeutic drugs or prognostic biomarkers for human cancers.

• Journal of Fisheries and Marine Sciences Education
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• v.12 no.1
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• pp.22-82
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• 2000

The ship hull construction materials of fishing boat has changed in order that wooden, steel, and fiber glass reinforced plastic(FRP). The fishing boat made from FRP has increased every year because that materials has proved excellent of the characteries for fishing boats construction members. Recently, FRP tend towards evasion for the pollution of air enviroment. Therefore. the materials of fishing boat construction must be exchanged by another one. Aluminium alloys must be recommended for fishing boats construction mateials because that is light weight and corrosion resisting in the sea water. Regulation of the standard of ship hull construction for aluminium alloys fishing boats did not enact laws in the interior now. Therefore, this regulation was studied by the following items. that is Rudder, Bottom construction, Side hull plate construction, Deck plate construction, piller. Water tight bulkhead, Deep tank, Fish tank, Stern construction, Superstructure, Deck house construction, Hatch, Engine room opening, Hatch opening, Bulwark, Welding and Rivet etc. A study on the regulation will be contributed to enact laws for fishing boat construction of aluminium alloys.

• Journal of Industrial Convergence
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• v.8 no.1
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• pp.49-64
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• 2010

Penalty tax of basic law that has been revised in December 30, 2006 has been amended to tax 40 percent on no report and under-reporting in unjustifiable way. This revision is a punitive regulation that reflects the national tax service's will to not sit back and watch taxpayers' intentional tax evasion by imposing a heavier tax burden, and it raised penalty tax rate that has been applied leniently compared to foreign countries. Therefore, this study examines how changes in penalty tax rate affected faithful tax report and in what level the punitive penalty tax rate should be legislated so that the effect of the penalty tax rate can be maximized by performing empirical analysis on the effect on income tax rate reporting standard of self-employed businesses before and after the time the penalty tax rate increased dramatically from 33.3% to 300% based on the items.

• Genomics & Informatics
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• v.16 no.4
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• pp.17.1-17.6
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• 2018

Tumor heterogeneity, the cellular mosaic of multiple lineages arising from the process of clonal evolution, has continued to thwart multi-omics analyses using traditional bulk sequencing methods. The application of single-cell sequencing, in concert with existing genomics methods, has enabled high-resolution interrogation of the genome, transcriptome, epigenome, and proteome. Applied to cancers, these single-cell multi-omics methods bypass previous limitations on data resolution and have enabled a more nuanced understanding of the evolutionary dynamics of tumor progression, immune evasion, metastasis, and treatment resistance. This review details the growing number of novel single-cell multi-omics methods applied to tumors and further discusses recent discoveries emerging from these approaches, especially in regard to immunotherapy.

• Journal of Information Processing Systems
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• v.15 no.1
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• pp.100-115
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• 2019

Malicious code distribution on the Internet is one of the most critical Internet-based threats and distribution technology has evolved to bypass detection systems. As a new defense against the detection bypass technology of malicious attackers, this study proposes the automated tracing of malicious websites in a malware distribution network (MDN). The proposed technology extracts automated links and classifies websites into malicious and normal websites based on link structure. Even if attackers use a new distribution technology, website classification is possible as long as the connections are established through automated links. The use of a real web-browser and proxy server enables an adequate response to attackers' perception of analysis environments and evasion technology and prevents analysis environments from being infected by malicious code. The validity and accuracy of the proposed method for classification are verified using 20,000 links, 10,000 each from normal and malicious websites.

• BMB Reports
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• v.54 no.11
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• pp.541-544
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• 2021

Protein glycosylation is a common post-translational modification found in all living organisms. This modification in bacterial pathogens plays a pivotal role in their infectious processes including pathogenicity, immune evasion, and host-pathogen interactions. Importantly, many key proteins of host immune systems are also glycosylated and bacterial pathogens can notably modulate glycosylation of these host proteins to facilitate pathogenesis through the induction of abnormal host protein activity and abundance. In recent years, interest in studying the regulation of host protein glycosylation caused by bacterial pathogens is increasing to fully understand bacterial pathogenesis. In this review, we focus on how bacterial pathogens regulate remodeling of host glycoproteins during infections to promote the pathogenesis.