• 한국의류산업학회지
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• 제12권2호
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• pp.194-202
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• 2010

There may be some problems in size fitness for ready-made-clothes purchasers with Obese body shape. The purpose of this study was to improve the wearing comfort of Junior-High School Girls' slacks by setting grading points and developing grading rules proper to the obesity. The subjects in this study was over 23 kg/m2 of the BMI. The subjects were 124 Junior-High School Girls of 12 to 14 year-old. The results of this study are as follows: (1) The size intervals of waist girth and hip girth were 3 cm and 4 cm respectively. The sizing system, which had frequencies more than 5%, was classified 8 cases. The majority segment is 76-97 size accounting for the 11.29% of subjects. (2) The measurements on 8 size from two groups after drawing slacks pattern on them revealed that the changed values of slacks front and back on the grading point marked are differ, indicating that it is needed to apply body shape. (3) The evaluation on the appearance for wearing slacks showed relatively high score, indicating that the grading between sizes within each group was effective. The studies on the body size distribution on each obesity pattern and on the setting size system reflecting characteristics of each body shape should be performed continuously.

• BMB Reports
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• 제42권2호
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• pp.91-95
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• 2009

Peroxisome proliferator-activated receptor $\alpha$ and estrogen are believed to be involved in metabolic changes leading to obesity. To test this relationship, we divided female wildtype and PPAR$\alpha$-deficient mice fed on a high fat diet into the following groups: mock-operated, ovariectomized (OVX), and $E_2$-treated. The visceral white adipose tissue and plasma cholesterol levels were increased significantly in wild type OVX and decreased in the $E_2$-treated group, but interestingly not in PPAR$\alpha$-deficient mice. The mRNA levels of lipoprotein lipase in adipose tissue were also increased in only wild type OVX and decreased significantly in $E_2$-treated mice. These novel results suggest the possibility of signaling crosstalk between PPAR$\alpha$ and $E_2$, causing obesity in vivo.

• 한국식생활문화학회지
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• 제30권6호
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• pp.797-803
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• 2015

Atopic dermatitis (AD) is usually caused by foods such as wheat, egg, milk, and peanuts, leading to common health problems in early childhood with complications like urtication. The aim of this study was to evaluate ethanol extracts of rice and rice snacks concentrated until the ethanol was completely eliminated and hot-air dried. In vitro analyses were carried out using murine macrophage RAW 264.7 cells. We measured cytotoxicity, nitric oxide (NO) production, and inflammatory cytokine level. The NO level of the cells exposed to lipopolysaccharide (LPS) was significantly reduced by rice and rice snack extracts. $TNF-{\alpha}$ level decreased in contrast to the LPS group, although a significant difference was not observed. On the other hand, IL-6 significantly decreased in both rice and rice snack extracts in a dose-dependent manner. The results of the present study suggest that rice and rice snack decreased NO and inflammatory cytokine levels. Therefore, rice could be useful as a raw material for relieving child atopic dermatitis caused by snacks made from wheat.

• Nutrition Research and Practice
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• 제7권2호
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• pp.96-102
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• 2013

Obesity, an intractable metabolic disease, currently has no medical treatment without side effects, so studies have been actively carried out to find natural compounds that have anti-obesity activity with minimum side effects. In this study, the anti-obesity effects of water extracts of seven Capsicum annuum L. varieties being Putgochu (Pca), Oyee gochu (Oca), Kwari putgochu (Kca), Green pepper (Gca), Yellow paprika (Yca), Red paprika (Rca) and Cheongyang gochu (Cca), were examined through the evaluation of lipoprotein lipase (LPL) mRNA expression level in 3T3-L1 cells (mouse pre-adipocytes). After capsaicin elimination by chloroform defatting, freeze-dried powder of Cca was treated to 3T3-L1 cells and anti-obesity effects were examined by determining the LPL mRNA level using the RT-PCR method. Of the primary fractions, only proven fractions underwent secondary and tertiary refractionating to determine anti-obesity effects. From seven different Capsicum annuum L., there was a significant decrease of the LPL mRNA expression level of 50.9% in Cca treatment compared to the control group. A significant decrease of the LPL mRNA expression level was shown in primary fractions (Fr) 5 (36.2% decrease) and 6 (30.5% decrease) of the Cca water extracts. Due to the impurities checked by UPLC chromatography, Fr 5 and 6 were refractionated to determine the LPL mRNA expression level. Treatment of Fr 6-6 (35.8% decrease) and Fr 5-6 (35.3% decrease) showed a significant decrease in the LPL mRNA expression level. When analyzed using UPLC, major compounds of Fr 6-6 and Fr 5-6 were very similar. Subsequently, we refractionated Fr 6-6 and Fr 5-6 to isolate the major peak for structure elucidation. Treatment of Fr 5-6-1 (26.6% decrease) and Fr 6-6-1 (29.7% decrease) showed a significant decrease in the LPL mRNA expression level. Consequently, the fractions may have a possibility to ameliorate obesity through the decrease of the LPL mRNA expression level.

• Journal of Nutrition and Health
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• 제57권2호
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• pp.196-210
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• 2024

본 연구에서는 정향과 마가목 복합물 (SS)의 항비만 효과를 알아보기 위해 실험을 진행하였다. SS 투여는 3T3-L1 세포 내 TG와 TC가 유의적으로 감소하는 효과를 나타냈으며, 지질 합성 관련 유전자와 지방산 산화 관련 유전자 발현을 조절하는 효과를 보여주었다. 비만이 유도된 C57BL/6 mice에서 SS 투여는 혈청 내 leptin 호르몬 수치를 감소시켰으며, AMPK/ACC/SREBP-1 경로를 경유하여 TG 합성을 억제하였다. 또한, 조직병리학적 분석을 통해 지질 축적과 지방세포의 크기가 감소된 것을 확인하였다. 따라서 SS는 비만의 예방과 치료를 위한 잠재력을 갖춘 소재로 사료된다.

• 한국산학기술학회논문지
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• 제19권11호
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• pp.166-181
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• 2018

본 연구의 목적은 비만환자의 비만을 감소시키기 위한 침술요법의 현황을 파악하고 침술요법의 내용과 효과를 파악하는 것이다. 문헌검색은 '비만', '침', '이침', '전기침' 등을 검색어로 하여 한국학술정보, 한국교육학술정보원, 국회도서관, Pubmed, CINAHL 등을 통해 2003년 1월부터 2017년 12월까지 발표된 연구논문을 검색하였다. 연구자가 원본을 확인한 후, 선정한 19편의 논문을 최종 분석 하였다. Scottish Intercollegiate Guideline Network의 체크리스트로 논문의 질적 평가를 실시한 결과 10점 만점에 9점인 연구가 1편, 10점 만점에 7-8점인 연구가 15편, 10점 만점에 6점인 연구가 2편, 10점 만점에 3점인 연구가 1편이었다. 침술요법의 내용을 파악한 결과 비만을 감소시키기 위한 경혈점은 shemen, hunger, LI-11(Quchi), LI-4(Hegu), St-25(Tianshu), St-44(Neiting) 등이었다. 침술요법 총 시행 횟수는 평균 16.9회이었고, 침술요법 중재 기간이 20일 혹은 72일인 연구에서의 침술요법 중재 빈도는 1회/1-2일이었고, 침술요법 중재 기간이 4-18주인 연구에서의 침술요법 중재빈도는 1-3회/주이었다. 분석한 연구결과에 의하면 침술요법은 신체계측수치의 감소, 혈당 및 혈중 지질 농도의 감소, 혈중호르몬 변화 등을 일으켜 비만환자의 비만을 감소시키는 효과가 있었다. 향후 비만환자의 비만감소를 위한 침술요법의 효과성을 평가하기 위해 잘 설계된 연구가 시급히 필요하다.

• 한국산학기술학회논문지
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• 제17권6호
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• pp.438-448
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• 2016

본 연구는 대학생들의 체중조절행동에 영향을 미치는 요인을 파악하고자 실시하였다. 연구대상자는 C지역 대학에 재학 중인 대학생을 대상으로 자가보고식 설문조사로 시행되었다. 조사기간은 2015.12.01-12.20일 까지였고, 분석대상은 289명 이었다. 자료는 기술적 통계, t-tset, ANOVA, pearson correlation과 stepwise multiple regression으로 분석 하였다. 그 결과 대학생들은 자신의 체형에 대한 인식에 왜곡된 현상이 두드러지며, 특히 타인평가에 의한 체형인식과 비만스트레스, 체중조절경험이 체중조절행동에 영향을 미치는 것으로 나타났다. 체중조절행동과의 상관관계에서는 본인체형인식(r=.31, p<.001), 타인평가체형(r=.30, p<.001), 비만스트레스(r=.43, p<.001)등이 체중조절행동과 관련성이 높게 나타났다. 다중회귀분석결과, 체중조절행동에 영향을 미치는 요인으로는 비만스트레스(${\beta}=.37$, p<.001), 타인평가체형(${\beta}=.15$, p=.009)이 밀접하게 관련되는 영향요인임을 알 수 있었으며, 이 변수들의 설명력은 20% 인 것으로 나타났다(F=37.30, p<.001). 결론적으로, 대학생의 체형인식에서 타인평가체형, 비만스트레스가 체중조절행동관련 예측요인으로 나타났다. 이러한 예측요인 등을 파악하여 자신의 체형을 객관적으로 판단하여 인식할 수 있고 적절한 체중조절을 할 수 있는 정보제공, 식이와 운동을 격려하는 예방프로그램, 건강교육 및 중재 프로그램의 개발과 실시가 필요하다고 생각된다.

• 사상체질의학회지
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• 제15권2호
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• pp.124-128
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• 2003

Background: Sasang Constitutional Medicine (SCM) is a component of Korean traditional medicine that classifies humans into four categories, according to their constitution (Taeyangin, Taeumin, Soyangin and Soeumin). We are unaware of previous assessments of SCM in non-Asian race groups. Objectives: To quantify body composition components in three race groups and to determine whether SCM has an independent effect on body composition components. Design: A cross-sectional evaluation of 76 adults (28 Caucasian, 21 African-American, 27 Asian). Body composition was estimated using dual energy x-ray absorptiometry. Results: SCM component had a significant effect on weight, fat, and lean mass regardless of race group (p <0.001).

• 동의생리병리학회지
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• 제25권4호
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• pp.715-720
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• 2011

We performed this study to assess pain in patients with knee osteoarthritis. Participants were 120 Patients(men 26 and women 94) with knee osteoarthritis. Pain evaluations were conducted using survey composed of 12 items by interview with oriental medicine doctor. Collected data were analyzed by IBM SPSS Statistics 19.0. Women were 3.8 times more than men(21.7% vs 78.3%). Approximately 80% of participants were overweight and obesity. Descending stair is most painful action for knee osteoarthritis patients. The average degree of knee pain was more than moderate. 5. People diagnosed as arthritis before had the much higher knee pain than never diagnosed before. This study showed female gender, overweight and obesity were associated with the risk of knee arthritis and participants complained knee pain more than moderate. It is hoped that our findings provide information that help the treatment of knee osteoarthritis.

• 보건교육건강증진학회지
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• 제14권2호
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• pp.1-16
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• 1997

Recently obesity which had not been at issue very much before comes to the fore as an important health problem. But women frequently attempt excessive weight controls not to cure obesity but to fit false norms of women's appearances. Both these trends and tendencies of perceiving themselves to be fatter than what thay are work as a kind of stressor which impose psychological burden on most women, and finally threaten their mental health. In this point, the purpose of this study was to analize the factors having an effect on women's weight-related stress. This study included a survey and obese level measurement of a systematic random samples of 431 E. University senior students for 17 days(from 13 May 1996 to 29 May 1996). As results, obese level, especially the subject's evaluation for her obese level, history of weight control, and strong weigh control beliefs that the success depends on herself influenced stress.