• Fashion & Textile Research Journal
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• v.12 no.2
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• pp.194-202
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• 2010

There may be some problems in size fitness for ready-made-clothes purchasers with Obese body shape. The purpose of this study was to improve the wearing comfort of Junior-High School Girls' slacks by setting grading points and developing grading rules proper to the obesity. The subjects in this study was over 23 kg/m2 of the BMI. The subjects were 124 Junior-High School Girls of 12 to 14 year-old. The results of this study are as follows: (1) The size intervals of waist girth and hip girth were 3 cm and 4 cm respectively. The sizing system, which had frequencies more than 5%, was classified 8 cases. The majority segment is 76-97 size accounting for the 11.29% of subjects. (2) The measurements on 8 size from two groups after drawing slacks pattern on them revealed that the changed values of slacks front and back on the grading point marked are differ, indicating that it is needed to apply body shape. (3) The evaluation on the appearance for wearing slacks showed relatively high score, indicating that the grading between sizes within each group was effective. The studies on the body size distribution on each obesity pattern and on the setting size system reflecting characteristics of each body shape should be performed continuously.

• BMB Reports
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• v.42 no.2
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• pp.91-95
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• 2009

Peroxisome proliferator-activated receptor $\alpha$ and estrogen are believed to be involved in metabolic changes leading to obesity. To test this relationship, we divided female wildtype and PPAR$\alpha$-deficient mice fed on a high fat diet into the following groups: mock-operated, ovariectomized (OVX), and $E_2$-treated. The visceral white adipose tissue and plasma cholesterol levels were increased significantly in wild type OVX and decreased in the $E_2$-treated group, but interestingly not in PPAR$\alpha$-deficient mice. The mRNA levels of lipoprotein lipase in adipose tissue were also increased in only wild type OVX and decreased significantly in $E_2$-treated mice. These novel results suggest the possibility of signaling crosstalk between PPAR$\alpha$ and $E_2$, causing obesity in vivo.

• Journal of the Korean Society of Food Culture
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• v.30 no.6
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• pp.797-803
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• 2015

Atopic dermatitis (AD) is usually caused by foods such as wheat, egg, milk, and peanuts, leading to common health problems in early childhood with complications like urtication. The aim of this study was to evaluate ethanol extracts of rice and rice snacks concentrated until the ethanol was completely eliminated and hot-air dried. In vitro analyses were carried out using murine macrophage RAW 264.7 cells. We measured cytotoxicity, nitric oxide (NO) production, and inflammatory cytokine level. The NO level of the cells exposed to lipopolysaccharide (LPS) was significantly reduced by rice and rice snack extracts. $TNF-{\alpha}$ level decreased in contrast to the LPS group, although a significant difference was not observed. On the other hand, IL-6 significantly decreased in both rice and rice snack extracts in a dose-dependent manner. The results of the present study suggest that rice and rice snack decreased NO and inflammatory cytokine levels. Therefore, rice could be useful as a raw material for relieving child atopic dermatitis caused by snacks made from wheat.

• Nutrition Research and Practice
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• v.7 no.2
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• pp.96-102
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• 2013

Obesity, an intractable metabolic disease, currently has no medical treatment without side effects, so studies have been actively carried out to find natural compounds that have anti-obesity activity with minimum side effects. In this study, the anti-obesity effects of water extracts of seven Capsicum annuum L. varieties being Putgochu (Pca), Oyee gochu (Oca), Kwari putgochu (Kca), Green pepper (Gca), Yellow paprika (Yca), Red paprika (Rca) and Cheongyang gochu (Cca), were examined through the evaluation of lipoprotein lipase (LPL) mRNA expression level in 3T3-L1 cells (mouse pre-adipocytes). After capsaicin elimination by chloroform defatting, freeze-dried powder of Cca was treated to 3T3-L1 cells and anti-obesity effects were examined by determining the LPL mRNA level using the RT-PCR method. Of the primary fractions, only proven fractions underwent secondary and tertiary refractionating to determine anti-obesity effects. From seven different Capsicum annuum L., there was a significant decrease of the LPL mRNA expression level of 50.9% in Cca treatment compared to the control group. A significant decrease of the LPL mRNA expression level was shown in primary fractions (Fr) 5 (36.2% decrease) and 6 (30.5% decrease) of the Cca water extracts. Due to the impurities checked by UPLC chromatography, Fr 5 and 6 were refractionated to determine the LPL mRNA expression level. Treatment of Fr 6-6 (35.8% decrease) and Fr 5-6 (35.3% decrease) showed a significant decrease in the LPL mRNA expression level. When analyzed using UPLC, major compounds of Fr 6-6 and Fr 5-6 were very similar. Subsequently, we refractionated Fr 6-6 and Fr 5-6 to isolate the major peak for structure elucidation. Treatment of Fr 5-6-1 (26.6% decrease) and Fr 6-6-1 (29.7% decrease) showed a significant decrease in the LPL mRNA expression level. Consequently, the fractions may have a possibility to ameliorate obesity through the decrease of the LPL mRNA expression level.

• Journal of Nutrition and Health
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• v.57 no.2
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• pp.196-210
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• 2024

Purpose: This study investigated the anti-obesity effects of a combination of Syzygium aromaticum L. and Sorbus commixta Hedl. (SS) in vitro and in vivo. Methods: The extracts of Syzygium aromaticum extract (SA) and Sorbus commixta extract (SC) were prepared individually using distilled water. They were mixed in a 1:2 ratio for use in the experiment. To assess the anti-obesity potential of SS in vitro, we examined cell proliferation, cellular triglyceride (TG), and total cholesterol (TC) levels, as well as lipogenesis and β-oxidation in 3T3-L1 cells. To confirm its anti-obesity potential in vivo, C57BL/6J mice were fed a 60% high-fat diet (HFD) to induce obesity. SA alone, SC alone, and their combination compound, SS (at a dosage of 200 mg/kg) were orally administered for 6 weeks. Thereafter, to conduct a comparative evaluation, serum analysis, western blotting of liver tissues, and histopathological analysis were performed. Results: Both SS200 and SS400 significantly inhibited the cellular TG and TC contents in the 3T3-L1 cells. Furthermore, treatment of the cells with SS (at a dose 200 and 400 ㎍/mL) also led to a noticeable regulation of key lipogenic and β-oxidation factors. Treatment of obese mice with SS resulted in a greater reduction in serum leptin and TG levels compared to treatment with the individual compounds (SA and SC). Furthermore, activation of AMP-activated protein kinase α by SS treatment resulted in the suppression of sterol regulatory element-binding proteins (SREBP)-1, leading to the inhibition of acetyl-CoA carboxylase (ACC) expression. Conclusion: Our results suggest that SS may have the potential to prevent obesity through a reduction in the TG and TC levels and regulation of lipogenesis and β-oxidation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.166-181
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• 2018

The aim of this review was to determine the status of acupuncture therapies in reducing obesity in obese patients and to determine the scheme and effectiveness of acupuncture therapies. Existing reports published between January 1, 2003 and December 31, 2017 in Kiss, Riss, National Assembly Library, Pubmed and CINAHL databases were searched electronically with the keywords obesity, acupuncture, auricular acupuncture, and electroacupuncture. After checking the original sources of the articles, 19 articles were included in the review. In a qualitative evaluation of the papers using a checklist from the Scottish Intercollegiate Guideline Network, one study scored 9 out of 10 points, 15 studies scored 7-8 out of 10 points, two studies scored 6 out of 10 points, and one study scored 3 out of 10 points. In the acupuncture therapy schemes, acupoints to reduce obesity included shemen, hunger, LI-11 (Quchi), LI-4 (Hegu), St-25 (Tianshu) and St-44 (Neiting). Acupuncture therapies were conducted for an average of 16.9 total sessions. In the studies that involved 20-day or 72-day duration for acupuncture therapies, the frequency of acupuncture therapies was 1 time/1-2 days. In the studies that involved 4- to 18-week duration for acupuncture therapies, the frequency of acupuncture therapies was 1-3 times/week. This study found acupuncture therapies were effective in reducing obesity, and acupuncture therapies reduced anthropometry, blood glucose and lipids and changed blood hormones. In the future, there is an urgent need for well-planned studies of the effectiveness of acupuncture therapies for reducing obesity in obese patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.438-448
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• 2016

This study was conducted to identify factors influencing the weight control behavior of college students. The subjects included college students in the C area, and data were collected through a self reported structured questionnaire from Dec 01 to 20 of 2015. Overall, 289 subjects were analyzed. Analyses consisted of descriptive statistics, t-tests, ANOVA, Pearson's correlation analysis, and stepwise multiple regression analysis. The findings showed a prominent distortion of college students' perceptions of their bodies based on evaluation by others and obesity stress, which had special impacts on their weight control behavior. Weight control behavior, body self-awareness (r=.31, p<0.001), assessment of body by others (r=.30, p<0.001), and obesity stress (r=.43, p<0.001) were closely related to their weight control behavior. Stepwise multiple regression revealed that their weight control behavior was closely influenced by obesity stress (${\beta}=.37$, p<0.001) and assessment of body by others (${\beta}=.15$, p=0.009). These variables accounted for 20% of the weight control behavior (F=37.30, p<0.001). Overall, assessment of body by others and obesity stress were found to be predictors of their weight control behavior. These findings indicate that it is necessary to develop and implement information programs and design appropriate prevention programs that can induce healthy weight control behaviors. Such programs should include health education, as well as intervention programs to identify such predictors and help college students judge and perceive their body shapes objectively so that they control their weight in a proper manner.

• Journal of Sasang Constitutional Medicine
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• v.15 no.2
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• pp.124-128
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• 2003

Background: Sasang Constitutional Medicine (SCM) is a component of Korean traditional medicine that classifies humans into four categories, according to their constitution (Taeyangin, Taeumin, Soyangin and Soeumin). We are unaware of previous assessments of SCM in non-Asian race groups. Objectives: To quantify body composition components in three race groups and to determine whether SCM has an independent effect on body composition components. Design: A cross-sectional evaluation of 76 adults (28 Caucasian, 21 African-American, 27 Asian). Body composition was estimated using dual energy x-ray absorptiometry. Results: SCM component had a significant effect on weight, fat, and lean mass regardless of race group (p <0.001).

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.715-720
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• 2011

We performed this study to assess pain in patients with knee osteoarthritis. Participants were 120 Patients(men 26 and women 94) with knee osteoarthritis. Pain evaluations were conducted using survey composed of 12 items by interview with oriental medicine doctor. Collected data were analyzed by IBM SPSS Statistics 19.0. Women were 3.8 times more than men(21.7% vs 78.3%). Approximately 80% of participants were overweight and obesity. Descending stair is most painful action for knee osteoarthritis patients. The average degree of knee pain was more than moderate. 5. People diagnosed as arthritis before had the much higher knee pain than never diagnosed before. This study showed female gender, overweight and obesity were associated with the risk of knee arthritis and participants complained knee pain more than moderate. It is hoped that our findings provide information that help the treatment of knee osteoarthritis.

• Korean Journal of Health Education and Promotion
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• v.14 no.2
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• pp.1-16
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• 1997

Recently obesity which had not been at issue very much before comes to the fore as an important health problem. But women frequently attempt excessive weight controls not to cure obesity but to fit false norms of women's appearances. Both these trends and tendencies of perceiving themselves to be fatter than what thay are work as a kind of stressor which impose psychological burden on most women, and finally threaten their mental health. In this point, the purpose of this study was to analize the factors having an effect on women's weight-related stress. This study included a survey and obese level measurement of a systematic random samples of 431 E. University senior students for 17 days(from 13 May 1996 to 29 May 1996). As results, obese level, especially the subject's evaluation for her obese level, history of weight control, and strong weigh control beliefs that the success depends on herself influenced stress.