• Title/Summary/Keyword: Evaluation of Research and Development Performance

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Development on Antibiotic Concrete Mixed with Antibacterial Metals and Metallic Salts (금속 및 금속염계 항균제가 혼입된 항균 콘크리트 개발)

  • Choi, Hong-Shik;Heo, Kwon;Lee, Ho-Beom;Lee, Si-Woo;Kwak, Hong-Shin
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.1 no.2
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    • pp.136-143
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    • 2013
  • In the sewage structures and wastewater facilities, concrete is exposed to hydrogen sulfide ($H_2S$) which acts as an acid material in a solution, and a strongly acidic sulfate ion ($SO{_4}^{-2}$) is generated by a sulfuric bacteria. Hence, a degradation of concrete with biochemical corrosion would be accelerated. Finally, durability of concrete and concrete structures may be greatly reduced. In this study, in order to remove the hydrogen sulfide which is used by the sulfuric bacteria organic-biologically, the antibiotic metal and metallic salt powders were mixed to concrete, and a suppressing performance of the sulfate ion was assessed. For the sulfuric acid bacteria, a comparative evaluation of antimicrobial performance on neutralized concrete specimens were carried out, also by a rapid chloride penetration test, chloride penetration depths and diffusion coefficients were measured for antibiotic concrete in accordance with the amount of metal and metallic salt-based antibacterial agents. Eventually, by an observation of the biochemical state of the surface of concrete specimens exposed outdoors, the performance and applicability of antibiotic concrete were confirmed.

Development and Evaluation of a Nursing Handoff Protocol for Intensive Care Units (중환자실 간호 인수인계 프로토콜의 개발 및 평가)

  • Cho, Young Shin;Kwon, Sun Ju;Yun, Mi Young;Lee, Mi Hwa;An, So Hee;Kong, Yu Jeong
    • Journal of Korean Critical Care Nursing
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    • v.9 no.2
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    • pp.1-12
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    • 2016
  • Purpose: This study aimed to develop a nursing handoff protocol for intensive care units and test its relevance. Methods: This is a methodological research to develop a protocol. A preliminary protocol was developed by composing items and testing content validity through literature review and experts' review. We revised and complemented the preliminary protocol following practical relevance assessment of 38 intensive care unit nurses at a university hospital to test content validity and to assess practical relevance of the final protocol. Results: On the basis of the content validity test for the final protocol, 40 items were adopted. The scores for the practical relevance of the final protocol increased significantly for items such as accuracy of handoff, reduction of handoff-related errors, convenience in using the protocol, reduction in handoff time, and simplification of handoff. Conclusions: The nursing handoff protocol for intensive care units in this study is expected to improve nursing performance with a standardized handoff in intensive care units, promote patient safety, and improve communication among the medical staff.

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Similarity Model Analysis and Implementation for Enzyme Reaction Prediction (효소 반응 예측을 위한 유사도 모델 분석 및 구현)

  • Oh, Joo-Seong;Na, Do-Kyun;Park, Chun-Goo;Ceong, Hyi-Thaek
    • The Journal of the Korea institute of electronic communication sciences
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    • v.13 no.3
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    • pp.579-586
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    • 2018
  • With the beginning of the new era of bigdata, information extraction or prediction are an important research area. Here, we present the acquisition of semi-automatically curated large-scale biological database and the prediction of enzyme reaction annotation for analyzing the pharmacological activities of drugs. Because the xenobiotic metabolism of pharmaceutical drugs by cellular enzymes is an important aspect of pharmacology and medicine. In this study, we apply and analyze similarity models to predict bimolecular reactions between human enzymes and their corresponding substrates. Thirteen models select to reflect the characteristics of each cluster in the similarity model. These models compare based on sensitivity and AUC. Among the evaluation models, the Simpson coefficient model showed the best performance in predicting the reactivity between the enzymes. The whole similarity model implement as a web service. The proposed model can respond dynamically to the addition of reaction information, which will contribute to the shortening of new drug development time and cost reduction.

Development and Application of a Source for Crosshole Seismic Method to Determine Body Wave Velocity with Depth at Multi-layered Sites (다층 구성 부지에서의 깊이별 실체파 속도의 결정을 위한 시추공간 탄성파 탐사 발진 장치 개발 및 적용)

  • Sun, Chang-Guk;Mok, Young-Jin
    • Geophysics and Geophysical Exploration
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    • v.9 no.3
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    • pp.193-206
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    • 2006
  • Among various borehole seismic testing techniques for determining body wave velocity, crosshole seismic method has been known as one of the most suitable technique for evaluating reliably geotechnical dynamic properties. In this study, to perform successfully the crosshole seismic test for rock as well as soil layers regardless of the groundwater level, multi-purposed spring-loaded source which impact horizontally a subsurface ground in vertical borehole was developed and applied at major facility sites in Korea. The geotechnical dynamic properties were evaluated by determining efficiently the body wave velocities such as shear wave velocity and compressional wave velocity from the horizontally impacted crosshole seismic tests at study sites, and were provided as the fundamental parameters for the seismic performance evaluation and seismic design of the target facilities.

Performance evaluation of Wave observation system using GPS (GPS를 이용한 파고 관측 시스템의 성능 평가)

  • Huh, Yong;Hwang, Chang-Su;Kim, Dae Hyun;Heo, Sin;Kim, Joo-Youn;Lee, Kee-Wook;Hong, Sung-Doo
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.15 no.4
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    • pp.357-362
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    • 2012
  • Despite the Wave observations data is very important information to human life at sea, the technology development and research for wave equipments are lacking. In this study, the wave observation system using GPS was evaluated the quality of wave observation data by comparing of long-term observations. The result of the comparison of the acceleration sensor (Hippy-40) and GPS sensor (Mose-1000), the correlation coefficient of the significant wave height and significant wave periods is 0.997 and 0.990 respectively. Also in case of BIAS, the significant wave height is 0.014 m, the significant wave period is -0.212 sec. It makes no significant differences whether the acceleration sensor (Hippy-40) and GPS sensor (Mose-1000). These results of the wave observation data using GPS quality will be evaluated as very good.

Monte Carlo Simulation for Radiation Protection Sheets of Pb-Free (무연 방사선 차폐 시트에 대한 몬테카를로 전산모사)

  • Chon, Kwon Su
    • Journal of the Korean Society of Radiology
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    • v.11 no.4
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    • pp.189-195
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    • 2017
  • Radiation protection equipment has widely used to protect human body from radiations, for example X-ray and gamma ray. The material of the radiation protection equipment is mainly lead (Pb) which has brought out lead poisoning and pollution when the equipment is fallen into disuse. This problem makes research and development find new Pb-free materials for use of radiation protection. Manufacturing and evaluation processes for developing those material were carried out repletely until obtaining the performance of protection rate. In this study, combination possibility of shielding material was studied using Geant4 monte carlo simulation. X-ray tube under the same condition in the real measurement of the protection rate was simulated, and X-ray tube spectrum was obtained. The X-ray tube spectrum was applied to study on the protection rate and lead equivalent. The porosity effect was simulated, and was one of key factors to determine protection rate or lead equivalent in radiation protection sheet of Pb-free.

Time Series Analysis for Predicting Deformation of Earth Retaining Walls (시계열 분석을 이용한 흙막이 벽체 변형 예측)

  • Seo, Seunghwan;Chung, Moonkyung
    • Journal of the Korean Geotechnical Society
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    • v.40 no.2
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    • pp.65-79
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    • 2024
  • This study employs traditional statistical auto-regressive integrated moving average (ARIMA) and deep learning-based long short-term memory (LSTM) models to predict the deformation of earth retaining walls using inclinometer data from excavation sites. It compares the predictive capabilities of both models. The ARIMA model excels in analyzing linear patterns as time progresses, while the LSTM model is adept at handling complex nonlinear patterns and long-term dependencies in the data. This research includes preprocessing of inclinometer measurement data, performance evaluation across various data lengths and input conditions, and demonstrates that the LSTM model provides statistically significant improvements in prediction accuracy over the ARIMA model. The findings suggest that LSTM models can effectively assess the stability of retaining walls at excavation sites. Additionally, this study is expected to contribute to the development of safety monitoring systems at excavation sites and the advancement of time series prediction models.

Preparation and Food Characteristics of Seasoned Anchovy Sauce with Improved Bitterness by Treatment of Aminopeptidase Active Fraction Derived from Common Squid Todarodes pacificus Hepatopancreas (살 오징어(Todarodes pacificus) 간췌장 유래 Aminopeptidase 활성획분에 의해 쓴맛이 개선된 멸치 조미소스의 제조 및 식품특성)

  • Yoon, In Seong;Kim, Jin-Soo;Choe, Yu Ri;Sohn, Suk Kyung;Lee, Ji Un;Kang, Sang In;Kwon, In Sang;Heu, Min Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.54 no.6
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    • pp.849-860
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    • 2021
  • This study investigated the preparation of seasoned anchovy sauce (SAS) and its functional characteristics by using aminopeptidase active fractions (AAFs) derived from squid Todarodes pacificus hepatopancreas as a bitter taste improver. As the base of the SAS, a hydrolysate (AAAH) prepared by continuously treating raw anchovies with Alcalase-AAF was used. The high-performance liquid chromatography profile of the AAAH suggested that the action of AAFs decreased the hydrophobicity of the N-terminal peptide related to bitterness in the protein hydrolysates. SAS was prepared by blending with the AAAH and other ingredients. The crude protein (2.5%), carbohydrates (18.4%), amino acid-nitrogen (1,325.1 mg/100 mL), and total free and released amino acids (FRAAs, 700.2 mg/100 mL) of SAS were higher than those of commercial anchovy sauce (CAS). Sensory evaluation revealed that SAS was superior to CAS in flavor, color, and taste. The main FRAAs of SAS were glycine (16.8%), alanine (13.2%), glutamic acid (7.8%), and leucine (7.3%). The amino acids that had a major influence on the taste according to the SAS taste values were glutamic acid, aspartic acid, alanine, and histidine. The angiotensin-converting enzyme inhibitory (2.21 mg/mL) and antioxidant activities (3.58 mg/mL) of SAS were superior to those of CAS.

Development of Maintenance Scenario Method for Small and Medium-sized Bridges Using Risk Matrix (리스크매트릭스를 활용한 중소규모 교량의 유지관리 시나리오 기법 개발)

  • Park, Hyun-Chan;Shin, Byoung-Gil;Cho, Choong-Yuen;Kim, Young-Min;Chang, Buhm-Soo
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.6
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    • pp.161-168
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    • 2021
  • This paper is a maintenance system for bridge represented by Class 3 and other than by law bridges. Domestic bridge are divided into Class 1 & 2 bridges and Class 3 & other than by law bridges. The number of type 3 and other than by law bridges is very large. But, it is considered to be of relatively low importance compared to Class 1 & 2 Bridge Bridge. So, in this paper is propose a maintenance system and procedure for small & medium-sized bridges. However, because the number of small & medium-sized bridges is large, it is not possible to evaluate the performance of all bridges like Class 1 & 2 bridge. The reason is the lack of manpower and budget. Based on the Risk Matrix method, a maintenance procedure was created to select the bridge for which performance evaluation should be performed first. For this purpose, basic information of the bridge is used. And, the developed maintenance procedures were applied to the bridges in actual use.

Evaluation of Experimental Formulated Diets and Commercial Diets for Growing Korean Rockfish (Sebastes schlegeli) (조피볼락 육석용 배합사료와 시판사료의 사육효과 비교)

  • Lee Sang-Min;Jeon Im-Gi
    • Journal of Aquaculture
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    • v.9 no.4
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    • pp.377-384
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    • 1996
  • A 15-week of growth trial was conducted to evaluate practical diets for growing Korean rockfish (Sebastes schlegeli). Two replicate groups of the fish average weighing 125 g were fed one of four experimental diets containing $41\~45\%$ protein and $6\~8\%$ lipid. A control diet with $58\%$ fish meal as protein source was included and practical form diets with $40\%$ fish meal and various practical ingredients such as meat meal, blood meal, soybean meal, and corn gluten meal were included. These experimental dry pellet diets were compared with commercial diets containing $51\~53\%$ protein and $5\~13\%$ lipid for marine fish or raw fish-based moist pellet (RMP) diet containing $58\%$ protein and $9\%$ lipid consisted of $50\%$ frozen horse mackerel and $50\%$ commercial binder meal. Weight gain, feed efficiency, daily feed intake and protein efficiency ratio in the fish fed the experimental diets and commercial diets were not significantly different to those in the fish fed the control diet. However weight gain, feed efficiency and protein efficiency ratio in the fish fed the RMP diet were significantly higher than those in the fish fed the experimental diets and commercial diets. These differences of growth performance between experimental diets and RMP diet may be reason for different dietary protein and energy levels. The experimental diet can save up to $20\%$ cost of fish production compare with control diet, whereas RMP diet is more expensive than other diets in the fish production.

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