• 대한방사선치료학회지
• /
• 제9권1호
• /
• pp.71-81
• /
• 1997

I. Objective and Importance of the Project We have been using MC-50 cyclotron and NT-50 neutron therapy machine for treating cancer patients since 1986 at Korea Cancer Center Hospital. It is mandatory to measure accurately the dose distribution and the total absorbed dose of fast neutron for putting it to the clinical use. At present the methods of measurement of fast neutron are proposed largely by American Associations of Physicists in Medicine (Task Group 18), European Clinical Neutron Dosimetry Group, and International Commission on Radiation Units and Measurements. The complexity of measurement, however, induce the methodological differences between them. In our study, therefore, we tried to establish a unique technique of measurement by means of measuring the emitted doses and the dose distribution of fast neutron beam from neutron therapy machine, and to invent a standard method of measurement adequate to our situation. II. Scope and Contents of the Project For establishing a unique technique of measurement and inventing a standard method of measurement of fast neutron beam, 1. to grasp the physical characteristics of neutron therapy machine 2. to study the principles for measrement of fast neutron beam 3. to get the dose distribution (dose rate, percent-depth dose, flatness etc) throught the actual measurement 4. to compare our data with those being cited world-widely.

• 한국식품위생안전성학회지
• /
• 제19권3호
• /
• pp.140-150
• /
• 2004

It has been recognized that international food standards should be considered for a long time. The Codex Alimentarius programme initiated in the early 1960s has received valuable background documentation from the ICMSF (International Commission on Microbiological Specification for Foods) and also from ISO(the International Organization for Standardization). There has been a considerable move towards international harmonization of standards and methods of analysis. Many foreign countries recommend the guidelines for food microbiological standards quantitatively. To complement microbiological limits and tolerance levels for permissible number of defective samples, allowances should be made for sampling and other variations in laboratory methods. It may be necessary for guidelines of domestic food microbiological standards to be established so that the domestic food standards can be harmonized with foreign food standards. Food safety related microbiological guidelines of ICMSF, EU (European Union), UK (United Kingdom), China (Hong Kong) and Japan were reviewed and shown in examples.

• Journal of Pharmaceutical Investigation
• /
• 제36권6호
• /
• pp.421-435
• /
• 2006

The objective of this report is to introduce the European Union's variation rules governing medicinal products that are subject to post-approval changes. The EMEA outlines a variety of changes occurring to approved medicinal products. It also recommends a marketing authorisation holder to follow specific post-approval applications in various situations. For instance, the Commission Regulation(EC) No. 1085/2003 explains variation types and suggests post-authorisation procedures with which an applicant should comply. In all cases of minor and major variations the applicant has to investigate and validate whether or not the intended changes would have impact on the safety, efficacy and quality of a drug product. The applicant should then submit to the EMEA a variation application with adequate documentation in support of the notified changes. This procedure is implemented to ensure that changes to the approved medicinal product do not cause my public health concerns. In fact, the post-authorisation guidance categorizes post-approval changes into type IA/IB variations, type II variations, and extension applications. Such classifications determine administrative procedures to be followed in an efficient manner. Based on the type of a variation, the regulatory agency opts to reduce or extend the evaluation time-frame. The thrust of the EU's post-authorisation guidance is introduced in text with appropriate explanation. All these information will be likely to be helpful in updating a Korean regulatory guidance that could better deal with post-approval changes to generic drugs available in the market.

• Earthquakes and Structures
• /
• 제7권4호
• /
• pp.449-462
• /
• 2014

Seismically induced structural damage, as well as any damage caused by a natural catastrophic event, covers a wide area. This suggests to supervise the event consequences by vision tools. This paper reports the evolution from the results obtained by the project RADATT (RApid Damage Assessment Telematics Tool) funded by the European Commission within FP4. The aim was to supply a rapid and reliable damage detector/estimator for an area where a catastrophic event had occurred. Here, a general open-source methodology for the detection and the estimation of the damage caused by natural catastrophes is developed. The suitable available hazard and vulnerability data and satellite pictures covering the area of interest represent the required bits of information for updated telematics tools able to manage it. As a result the global damage is detected by the simple use of open source software. A case-study to a highly dense agglomerate of buildings is discussed in order to provide the main details of the proposed methodology.

• Smart Structures and Systems
• /
• 제4권2호
• /
• pp.195-208
• /
• 2008

This paper summarizes the experimental vibration-based structural health monitoring study on a historical monument in Jordan. In this work, and within the framework of the European Commission funded project "wide-Range Non-Intrusive Devices Toward Conservation of Historical Monuments in the Mediterranean Area", a seven and a half century old minaret located in Ajloun (73 km north of the capital Amman) is studied. Because of their cultural value, touristic importance and the desire to preserve them for the future, only non-destructive tests were allowed for the experimental investigation of such heritage structures. Therefore, after dimensional measurements and determination of the current state of damage in the selected monument, ambient vibration tests are conducted to measure the accelerations at strategic locations of the system. Output-only modal identification technique is applied to extract the modal parameters such as natural frequencies and mode shapes. A Non-linear version of SAP 2000 computer program is used to develop a three-dimensional finite element model of the minaret. The developed numerical model is then updated according to the modal parameters obtained experimentally by the ambient-vibration test-results and the measured characteristics of old stone and deteriorated mortar. Moreover, a parametric identification method using the N4Sid state space model is employed to model the dynamic behavior of the minaret and to build up a robust, immune and noise tolerant model.

• 한국철도학회:학술대회논문집
• /
• 한국철도학회 2007년도 춘계학술대회 논문집
• /
• pp.968-973
• /
• 2007

The systems such as the railway control system, satellite control system and nuclear power plant control system are the safety critical systems because the failure of them could lead to risk significant events. These softwares of digital systems must follow the life cycle process from the beginning of software development to guarantee their safety and reliability. The NRC(Nuclear Regulatory Commission) Reg Guide of nuclear fields, the RTCA/DO-178B standard which is used to acquire the certification for software in industrial aero field in European Union and United State, the DEF STAN 00-55 standard for the safety of electronic weapon in England, the IEC 601-1-4 for medical equipment and the IEC 62279 for railway system recommended the development life cycle. This paper introduces the development process and compares each other. Also it indicates applicable development criteria for the software of systems related to railway fields and describes the detailed procedure of development criteria. We describe the procedure to make the software development criteria in nuclear filed. For the software development related to railways, the process from plan phase to maintenance phase must be satisfied. The safety and reliability is guaranteed through these standards.

• 해운
• /
• 통권92호
• /
• pp.16-26
• /
• 2012

유럽연합(EU)의 집행위원회(European Commission)가 국제 화물운송료를 담합한 글로벌 물류기업에 대규모 과징금을 부과했다. EU 경쟁당국은 쿠네&네이젤(Khune+Nagel), 판알피나(Panalpina), 유피에스(UPS) 등에 총 1억 6,900만 유로의 과징금을 부과했다. EC는 총 14개의 회사가 화물운송 가격 담합에 가담하여, 미국 유럽 아시아 등으로 운송되는 화물의 운송비를 불법적으로 책정한 것으로 판단하였다. 한편 DHL은 자진신고를 통해 리니언시(liniency) 적용으로 과징금을 부과 받지 않았다. 유럽연합은 이러한 국제카르텔에 대한 법집행 차원에서 과징금 부과 및 당해행위에 대한 금지명령 등 행정적 제재를 강화하며, 세계 경쟁정책 및 법집행을 주도하고 있다. 또한 유럽연합은 해운동맹 폐지를 비롯한 해운업계의 반경쟁적 행위에 대한 제한도 강화하고 있다. EU는 2008년 10월부터 해운동맹의 공동가격설정 및 선복량 조절 행위를 금지하고 있다. 유럽집행위원회는 지난해 5월 초 13개 컨테이너 선사의 유럽 사무소를 기습 감사, 조사하였다. 현재 EU는 자료조사 중이며 결과는 아직까지 확인되지 않고 있다. EU의 조사는 상당히 지체되는 경향이 있는데, 향후 추가 질의서 요구가 예상되며 불법행위가 밝혀질 경우 개별 기업 글로벌 수익의 10%에 해당하는 벌금 부과가 가능하며, 영국에서는 형사고발도 가능하다. 다음은 한국해양수산개발원 최영석 전문연구원이 발표한 "국제해운의 해운동맹 폐지 및 담합행위 제한 강화"의 주요 내용을 요약정리한 것이다.

• 한국정보처리학회:학술대회논문집
• /
• 한국정보처리학회 2016년도 춘계학술발표대회
• /
• pp.10-13
• /
• 2016

정부는 K-ICT 클라우드 활성화를 위해 정부 3.0 클라우드 추진 계획을 발표하고 관련 제도와 법률을 제정하여 클라우드 서비스 도입을 위한 정책을 추진하고 있다. 그러나 공공 분야의 클라우드 컴퓨팅 도입은 기존의 법률, 제도, 관행의 통제로 인해 미미한 실정이다. 공공 기관의 클라우드 컴퓨팅 도입 활성화를 위해 중요한 부분은 클라우드 컴퓨팅의 성능과 품질 등에 대한 특성을 파악하는 것이다. 클라우드 컴퓨팅의 특성을 알아야만 적격의 클라우드 컴퓨팅 사업자 선정이 가능하게 된다. 유럽 연합(European Commission)에서는 클라우드 컴퓨팅의 특성을 서비스 성능과 품질에 대한 일반특성, 기술성, 경제성으로 분류하고 있다. 그러나 클라우드 도입을 위한 설계 시 공공 기관 담당자는 클라우드 특성의 각 부문별 하위 항목에 대한 상세한 내용과 수준까지 객관적으로 평가하기 어렵다. 이러한 문제를 해결하고자 본 연구는 클라우드 컴퓨팅의 성능과 품질 및 기술 특성을 파악하여 각 특성에 대한 가중치를 구하고 우선순위 측정을 통해 사업자 선정을 위한 평가 기준으로 적용하는 기법을 제안한다.

• 한국지하수토양환경학회지:지하수토양환경
• /
• 제19권6호
• /
• pp.24-29
• /
• 2014

To data, there was no systematic basis for establishing the content and allowed levels of general contamination substances in the Korean groundwater quality standards for non-drinking water. Recently, use of specific procedures for deriving valid groundwater quality standards have become mandatory. This study first investigated the methodology for deriving groundwater quality standards in the European Commission (EC), considering background groundwater quality and domestic and international standards related to water quality. Furthermore, this study investigated the existing specified procedure of standards related to water quality (e.g. surface water, drinking water, and wastewater). Our findings showed that EC and Member States presented the methods for deriving groundwater threshold values for general chemicals. Finally, we have proposed the following procedures of deriving Korean groundwater quality: (1) Selection of groundwater pollutant population, (2) selection and monitoring of priority substances, (3) monitoring, (4) selection of groundwater quality standard candidates, (5) selection of new substances and values for groundwater quality standards.

• Nuclear Engineering and Technology
• /
• 제53권10호
• /
• pp.3133-3150
• /
• 2021

This work deals with the validation of a high-fidelity multiphysics system coupling the Serpent 2 Monte Carlo neutron transport code with SUBCHANFLOW, a subchannel thermalhydraulics code, and TRANSURANUS, a fuel-performance analysis code. The results for a full-core pin-by-pin burnup calculation for the ninth operating cycle of the Temelín II VVER-1000 plant, which starts from a fresh core, are presented and assessed using experimental data. A good agreement is found comparing the critical boron concentration and a set of pin-level neutron flux profiles against measurements. In addition, the calculated axial and radial power distributions match closely the values reported by the core monitoring system. To demonstrate the modeling capabilities of the three-code coupling, pin-level neutronic, thermalhydraulic and thermomechanic results are shown as well. These studies are encompassed in the final phase of the EU Horizon 2020 McSAFE project, during which the Serpent-SUBCHANFLOW-TRANSURANUS system was developed.