• Advances in Traditional Medicine
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• 제7권2호
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• pp.133-140
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• 2007

Anti-tumor activity of Euphorbia hirta (50 mg/kg and 100 mg/kg) has been evaluated against Ehrlich's ascites carcinoma (EAC) in Swiss albino mice. Intraperitoneal (i.p) administration of Euphorbia hirta was effective in reducing solid tumor mass development induced by EAC cells. It exhibited significant anti-tumor activity in mice, when used at the dose of 100 mg/kg/day i.p., for 14days. The administration of Euphorbia hirta (100 mg/kg/day i.p.) resulted in an increase (P<0.001) of the life span (59.9%) of ascites tumor bearing mice as compared to the control group. After 14 days, on developed tumor masses, Euphorbia hirta administration brought about significant reduction in tumor volume and it reverse the changes in the hematological parameters, responding to tumor inoculation. The results are indicative of the anti-tumor activity of Euphorbia hirta against EAC induced tumor in a dose dependent manner.

• 식물분류학회지
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• 제41권2호
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• pp.164-170
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• 2011

부산광역시와 제주도에서 대극과의 미기록 귀화식물 2종을 발견하였다. Euphorbia heterophylla L. (아메리카대극)은 부산광역시 동래구 안락동 수영강변 공원에서 확인되었으며, E. dentata Michx. (톱니대극)과 비교하여 원줄기 잎은 호생하며, 소총포의 선체 입구는 원형인 특징으로 구별된다. 또한 Euphorbia hirta L. (털땅빈대)은 제주특별자치도 서귀포시 예래동 예래마을에서 확인되었으며, E. hypericifolia L. (큰땅빈대)와 비교하여 삭과에 털이 있는 특징으로 구별된다.

• Advances in Traditional Medicine
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• 제3권4호
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• pp.191-195
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• 2003

Euphorbia hirta, locally called 'ara tanah' or 'susun nabi' in Malaysia is a small annual herb common to the tropical countries and belongs to the same family as the tic and tapioca. E. hirta has had a long history of usage in the treatment of various ailments. In this current study, in vitro sensitivity test of crude aqueous and ethanol extracts of leaves and barks of E. hirta was carried out against bacteria (Escherichia coli, Salmonella enteritidis, Staphylocccus aureus and Bacillus subtilis) and fungi (Microsporum canis, Aspergillus fumigatus, Candida albicans and Candida tropicalis) using the discs diffusion method. The extract-impregnated discs (20, 40 and $80\;{\mu}g/{\mu}l$), the E. hirta extracts inhibited the growth of all the bacteria tested. The growth of C. albicans was inhibited in a concentration dependent manner by the aqueous leaves and barks extracts. C. tropicalis was found to be sensitive to the aqueous leaves extracts. The results were compared to antibacterial drugs of chloramphenicol, ampicilin, penicillin G, and enrofloxacine; and to antifungal drug of ketoconazole, itraconazole and miconazole. In this current study, it can be concluded that this plant has antimicrobial activity that is as potent as the standard antimicrobial drugs against certain microorganisms.