• Title/Summary/Keyword: Escape distance

Search Result 47, Processing Time 0.029 seconds

Effects of Daejo-hwan(Tatsao-wan) on L-NAME Induced Learning and Memory Impairment and on Cerebral Ischemic Damage of the Rats (L-NAME으로 유발된 학습.기억장애와 뇌허혈 손상에 관한 대조환의 효과)

  • 김근우;구병수
    • The Journal of Korean Medicine
    • /
    • v.21 no.2
    • /
    • pp.25-36
    • /
    • 2000
  • Objectives : This study demonstrates the effects of Daejo-hwan on learning and memory impairment induced by L-NAME (75 mg/kg) treatment and on cerebral ischemic damage induced by middle cerebral artery (MCA) occlusion in rats. Methods : Daejo-hwan emulsion (73.3 mg/100 g/l ml) was administered to rats along a timed study schedule. The Moms water maze was used for learning and memory test of the rats. The MCA was occluded by using the intraluminal thread method. The brain slices were stained by 2 % triphenyl tetrazolium chloride (TTC) and 1 % cresyl violet solution. Infarct size, neuron cell number and size in penumbra was measured by using computer image analysis system. Results : 1. The escape latency of the Daejo-hwan treated group decreased significantly with respect to the control group. 2.The memory score of the Daejo-hwan treated group showed increase tendency, And the swimming distance was not different between the normal, the control, and the Daejo-hwan treated group. 3. The infarct size of the Daejo-hwan treated group decreased significantly with respect to the control group. 4. The total infarct volume of the Daejo-hwan treated group showed decrease tendency. And the brain edema index of the Daejo-hwan treated group decreased significantly with respect to the control group. 5. The neuron cell number and cell size in penumbra of the Daejo-hwan treated group increased significantly with respect to the control group. Conclusions : According to the above results, it is supposed that Daejo-hwan is clinically applicable to the vascular dementia.

  • PDF

A study on quantitative risk assessment for railway Tunnel fire (철도터널에서 차량화재시 정량적 위험도 평가에 관한 연구)

  • Yoo, Ji-Oh;Nam, Chang-Ho;Jo, Hyeong-Je;Kim, Jong-Won
    • Journal of Korean Tunnelling and Underground Space Association
    • /
    • v.12 no.4
    • /
    • pp.307-319
    • /
    • 2010
  • As we learned in Daegu subway fire accident, fire in the railway tunnel is prone to develop to large disaster due to the limitation of smoke control and smoke exhaust. In railway tunnel, in order to ensure fire safety, fire prevention and fighting systems are installed by quantitative risk assessment results. Therefore, in this research, developed the program to establish quantitative risk assessment and suggested quantitative safety assessment method including fire scenarios in railway tunnel, fire and evacuation analysis model, fatality estimate model and societal risk criteria. Moreover, this method applys to plan preventing disaster for Honam high speed railway tunnel. As results, we presented the proper distance of escape route and societal risk criteria.

The Opening Efficiency of Labor Saving net for the Anchovy Boat Seine (생력형 기선권현망 어구의 전개성능)

  • Jang, Choong-Sik;An, Young-Su;Kim, Koang-Hong
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.41 no.1
    • /
    • pp.9-16
    • /
    • 2005
  • This study was conducted in order to improvement of fishing gear and fishing operating system for anchovy boat seine by labor saving improved nets. Field experiments were carried out observe geometry of nets and fishing operating system by catcher boats. The obtained results are summarized as follows : The Vertical net opening of fore wing net, wing net, inside wing net, square, fore bag net, flapper, after bag net of the labor saving improved net according to the distance between catcher boats were varied in the range of 5.0${\sim}$7.8, 14.4${\sim}$21.1, 16.2${\sim}$21.2, 14.0${\sim}$17.3, 11.7${\sim}$13.9, 5.4${\sim}$6.9, 8.2${\sim}$9.8m respectively, varied in the range of 50${\sim}$78, 25${\sim}$36, 24${\sim}$31, 31${\sim}$38, 61${\sim}$73, 71${\sim}$91, 87${\sim}$104% of the actual ratio of net opening in each part. Labor saving improved net was performed instant net opening in fore wing net and maintained stable net opening and towing depth by means of attached net pendant. Also, it was minimized as net pocket phenomenon leading to guide anchovy for more catch by means of attached body net. The opening in accordance with distance between catcher boats and towing speed. The catch of labor saving improved net was increased than traditional net due to decrement of net resistance by improvement of bag net leading to increasement of towing speed and reduction of escape anchovy as well as improve nets of whole operation system.

Viewing afar of Nature and Aesthetic Character in Sijo (시조(時調)에 나타난 산수자연(山水自然)의 원망(遠望)과 그 미적(美的) 성격(性格))

  • Choi, Dong-Kook
    • Sijohaknonchong
    • /
    • v.30
    • /
    • pp.9-20
    • /
    • 2009
  • The purpose of this study is to consider factors such as one's sight of viewing afar, expressional principles, and basic aesthetic category, which are treated importantly by the poets of the Joseon Dynasty era in appreciating nature. 'Afar' of the viewing afar is actual distance and aesthetic distance at the same time. Viewing afar is to find geographical features, depth, and details of a mountain, seeing the whole nature at a high place. Also, it can make possible escape from the external limitation of nature and get mental superiority and enhancement. Ultimately, viewing afar is to find out everlasting change of the nature and reason of natural creation. One's sight in viewing afar makes an appreciator's mind empty and calm, and it makes chance to harmonize human with nature. Viewing afar is to unite human nature to naturality beyond realistic value, idea, and artificiality. The mind from viewing afar has peacefulness and it is a state of serenity without any secular atmosphere. Viewing afar is an eye for beauty to leap toward an endless free state from narrow sight about objects. It rejects modification and technics in achieving an world of harmony. It means that objects should not be restrained by human's recognition. There are three expressions, which are high, horizontal, and transcendental viewing afar. The aesthetic category and beauty of peaceful mental state are realized by the expressions. The peaceful mental state makes peaceful mind from realistic conflicts and makes us experience a profound reason of nature.

  • PDF

Functional recovery after transplantation of mouse bone marrow-derived mesenchymal stem cells for hypoxic-ischemic brain injury in immature rats (저산소 허혈 뇌 손상을 유발시킨 미성숙 흰쥐에서 마우스 골수 기원 중간엽 줄기 세포 이식 후 기능 회복)

  • Choi, Wooksun;Shin, Hye Kyung;Eun, So-Hee;Kang, Hoon Chul;Park, Sung Won;Yoo, Kee Hwan;Hong, Young Sook;Lee, Joo Won;Eun, Baik-Lin
    • Clinical and Experimental Pediatrics
    • /
    • v.52 no.7
    • /
    • pp.824-831
    • /
    • 2009
  • Purpose : We aimed to investigate the efficacy of and functional recovery after intracerebral transplantation of different doses of mouse mesenchymal stem cells (mMSCs) in immature rat brain with hypoxic-ischemic encephalopathy (HIE). Methods : Postnatal 7-days-old Sprague-Dawley rats, which had undergone unilateral HI operation, were given stereotaxic intracerebral injections of either vehicle or mMSCs and then tested for locomotory activity in the 2nd, 4th, 6th, and 8th week of the stem cell injection. In the 8th week, Morris water maze test was performed to evaluate the learning and memory dysfunction for a week. Results : In the open field test, no differences were observed in the total distance/the total duration (F=0.412, P=0.745) among the 4 study groups. In the invisible-platform Morris water maze test, significant differences were observed in escape latency (F=380.319, P<0.01) among the 4 groups. The escape latency in the control group significantly differed from that in the high-dose mMSC and/or sham group on training days 2-5 (Scheffe's test, P<0.05) and became prominent with time progression (F=6.034, P<0.01). In spatial probe trial and visible-platform Morris water maze test, no significant improvement was observed in the rats that had undergone transplantation. Conclusion : Although the rats that received a high dose of mMSCs showed significant recovery in the learning-related behavioral test only, our data support that mMSCs may be used as a valuable source to improve outcome in HIE. Further study is necessary to identify the optimal dose that shows maximal efficacy for HIE treatment.

Installation Technology and Behavior of Silty Clay Filled Geotextile Tube (실트질 점토 채움 시 지오텍스타일 튜브의 거동 및 시공 방법에 관한 연구)

  • Shin, Eun-Chul;Oh, Young-In
    • Journal of the Korean Geosynthetics Society
    • /
    • v.1 no.1
    • /
    • pp.13-21
    • /
    • 2002
  • Geotextile tubes hydraulically or mechanically filled with dredged materials have been applied in hydraulic and coastal engineering in recent years(detached breakwater, groins and jetty). The geotextile tubes are made of sewn geosynthetics sheets. If the sandy soil is use to fill material, these inlets should be spaced closely to assure uniform filling of the tubes because sandy soil and geosynthetic is very pervious. However, the clayey soil or contaminated slurry is used, the inlets can be located relatively long distance. The fine clayey particles tend to rapidly blind the fabric slowing down water escape through the geotextile. This paper presents a field test result of a geotextile tube in the land reclamation project for the Songdo New City construction site. The dredged silty clay was dredged by the dredging ship and hydraulically pumped into the geotextile tube. The height of geotextile tube was measured at every filling stage and also measured width and diameter of geotextile tube with the elapsed time. Based on the test results, if the clayey filling material is used, the pumping step must be divided 3~4 stages for drainage and sediment. After complete drainage, the height of the geotextile tube reduces by approximately 50%.

  • PDF

A Study on Radiation Exposure Dose of Patients and Operator during Percutaneous Vertebroplasty (경피적 추체 성형술 시행 시 환자와 시술자의 방사선 피폭선량에 관한 연구)

  • Lee, Jae-Heon;Shin, Seong-gyu;Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
    • /
    • v.11 no.2
    • /
    • pp.139-144
    • /
    • 2017
  • Percutaneous vertebroplasty (PVP) is increasingly used to treat osteoporotic vertebral fractures, myeloma and osteolytic vertebral metastases. The purpose of this study was to measure the absorbed radiation exposure dose and time during PVP and to assess the possibility of deterministic radiation effects to the operator and patient. The radiation dose and time measure by three pain physicians performed consecutive procedures using the twenty case PVP. Patient's dosimeter placed at the anteroposterior(AP) side was treatment of the vertebra body located in the upper level 2-3 and lateral(LAT) side was flank proximal to C-arm tube of back. Operator's dosimeter placed at the apron outside of upper sternum (thyroid), left chest, lower extremity and apron inside of left chest. Results: Radiation exposure times were $3.6{\pm}0.71min$. Measurements on the Patient radiation dose were AP $121.4{\pm}48.1{\mu}Sv$, LAT side $614.7{\pm}177.1{\mu}Sv$. Operator radiation dose were outside of the lead apron upper sternum $33.7{\pm}7.3{\mu}Sv$, outside of the lead apron chest $49.2{\pm}15.0{\mu}Sv$, outside of the lead apron lower extremity $12.8{\pm}3.8{\mu}Sv$ and inside of the lead apron chest $4.2{\pm}1.4{\mu}Sv$. To escape from the danger of radiation first long distance from the c-arm tube second exposure time reduced second lead apron used fluoroscopy during PVP is more safety patient and operation from the radiation exposure.