• Title/Summary/Keyword: Epidemiological Investigation

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A Case Report of Human Brucellosis Found by Zoonoses Surveillance System Based on One Health (원헬스 기반 인수공통감염병 감시체계로 발견한 브루셀라증 사례)

  • Kim, Dong-Seob;Park, Sung-Jun;Lee, Kwan
    • Journal of agricultural medicine and community health
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    • v.44 no.2
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    • pp.90-93
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    • 2019
  • Brucellosis is one of the zoonoses, and it is a disease that is almost eliminated in South Korea. This disease is also known as a representative disease of one health. We would like to introduce brucellosis found by one health in this study. One Health means an approach in which multiple sectors communicate and work together to achieve better public health outcomes. The Gyeongbuk Agricultural Safety and Health Center established a cooperation system between a Veterinary Service Laboratory and a Public Health Center, and found a case of human brucellosis in a farm with cattle brucellosis. Through this case, to be effective control of zoonoses as above case, epidemiological investigation for cattle and human should be concurrently conducted. And we once again recognized the need for multi-sectoral cooperation in prevention and management of zoonoses.

Assessment of radiation exposure from cesium-137 contaminated roads for epidemiological studies in Seoul, Korea

  • Lee, Yun-Keun;Ju, Young-Su;Lee, Won Jin;Hwang, Seung Sik;Yim, Sang-Hyuk;Yoo, Sang-Chul;Lee, Jieon;Choi, Kyung-Hwa;Burm, Eunae;Ha, Mina
    • Environmental Analysis Health and Toxicology
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    • v.30
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    • pp.5.1-5.8
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    • 2015
  • Objectives We aimed to assess the radiation exposure for epidemiologic investigation in residents exposed to radiation from roads that were accidentally found to be contaminated with radioactive cesium-137 ($^{137}Cs$) in Seoul. Methods Using information regarding the frequency and duration of passing via the $^{137}Cs$ contaminated roads or residing/working near the roads from the questionnaires that were obtained from 8875 residents and the measured radiation doses reported by the Nuclear Safety and Security Commission, we calculated the total cumulative dose of radiation exposure for each person. Results Sixty-three percent of the residents who responded to the questionnaire were considered as ever-exposed and 1% of them had a total cumulative dose of more than 10 mSv. The mean (minimum, maximum) duration of radiation exposure was 4.75 years (0.08, 11.98) and the geometric mean (minimum, maximum) of the total cumulative dose was 0.049 mSv (<0.001, 35.35) in the exposed. Conclusions An individual exposure assessment was performed for an epidemiological study to estimate the health risk among residents living in the vicinity of $^{137}Cs$ contaminated roads. The average exposure dose in the exposed people was less than 5% of the current guideline.

The Role and Policy of Korean Medicine Doctor for the Prevention and Management of Infectious Diseases: A Mixed-Methods Approach (감염병 예방 및 관리를 위한 한의사의 역할과 정책적 과제: 혼합연구방법론을 적용하여)

  • Juchul Kim;Heasun Chun;HeeJung Lee;Jungtae Leem
    • The Journal of Korean Medicine
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    • v.44 no.2
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    • pp.45-59
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    • 2023
  • Objectives: This study investigated the role of Korean medicine doctors in the national quarantine system and the status of their duties through questionnaire surveys and in-depth interviews with Korean medicine staff who participated in COVID-19 work. Methods: We developed a questionnaire survey to investigate the status and perception of Korean medicine doctors' participation in responding to infectious diseases, and the results were derived by conducting frequency analysis and T-test using SPSS program. The measurement variables of this study were the status of COVID-19 related work participation and perception of Korean medicine doctors' role in infectious diseases, and the maximum significance level was 0.05. Results: There were 300 respondents to the survey, and as for the COVID-19 related work, Korean medicine treatment for COVID-19 patients accounted for the most(52.7%), and various preventive and treatment tasks such as epidemiological investigations and specimen collection were conducted. Conclusion: According to this study, it was confirmed that there are sufficient legal and administrative grounds for Korean medicine doctors to perform specimen collection and epidemiological investigations. Therefore, it is necessary to prepare a policy framework to solidify the status of Korean medicine doctors in national infectious diseases in the future.

Epidemiological Investigation of Diseases in Dairy Suckling Calves (젖소 신생송아지의 질병발생에 관한 조사연구)

  • 권오덕;김남수;채준석;박명규;김민석;유제춘;이주묵
    • Journal of Veterinary Clinics
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    • v.17 no.1
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    • pp.102-108
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    • 2000
  • This study was carried out to investigate the epidemiological prevalence of diseases from birth to weaning in 66 dairy calves which were delivered from three stock farm in Chonbuk area. We examined body weight gain, incidence rate of diseases and population mortality rate in relation to age, season, environmental temperature and rearing management conditions for one year. The results of this experiment were as follows: Birth weight of dairy calves born of primiparae was lower than those of multiparae. But no significant difference in body weight gain was observable between dairy calves born of primiparae and those of multiparae. Body weight gain of diseased calves was lower than normal calves. Of 66 delivered calves, 34 calves(51.5%) were affected with gastronitestinal and/or respiratory diseases. The prevalence of the diseases were gastrointestinal disease(28.7%), respiratory disease(18.2%), and gastronitestinal and respiratory disease(4.6%). The gastronitestinal disease was occurred contrinually regardless of the season. Whereas all of the respiratory disease were occurred in winter and a change of season(December to April). 68.4% of the gastronitestinal disease, and all of the respiratory disease were occurred at atmospheric temperatures below 1$0^{\circ}C$. 89.5% of the gastronitestinal disease were occurred within 3 weeks old, whereas 50% of the respiratory disease were occurred intensively between 3 weeks and 4 weeks old. Of 66 delivered dairy claves, 2 calves were died(3%) with respriratory disease.

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Epidemiological Investigation of Staphylococcus aureus Isolated from Bovine Mastitis Based on the Polymorphism of Coagulase Gene (젖소 유방염 유래 Staphylococcus aureus의 Coagulase Gene 유전형 분석에 의한 감염경로 규명)

  • Moon, Jin-San;Lee, Ae-Ri;Lym, Suk-Kyung;Joo, Yi-Seok;Kang, Hyun-Mi;Kim, Jong-Man;Kim, Mal-Nam
    • Korean Journal of Veterinary Research
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    • v.43 no.1
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    • pp.95-102
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    • 2003
  • Because Staphylococcus aureus (S. aureus) has variable number of short sequence repeat region in coagulase gene, it has been used to investigate the relatedness of S. aureus isolates. In this study, we isolated S. aureus strains from 20 dairy farms with bovine mastitis from September 2000 to August 2001. PCR-RFLP analysis of coagulase gene revealed 10 different patterns. Most of the S. aureus isolates showed only one coagulase gene RFLP pattern per farm. However, there were several S. aureus clones spreading between dairy farms. All the farms showed poor management conditions of milking machine and milker, indicating that managements for mastitis control program include use of proper milking matching, premilking sanitation, and segregation in the S. aureus infection herd. Our data suggest that PCR-RFLP analysis of coagulase gene might be applicable for the epidemiological investigations of S. aureus isolated from bovine mastitis cows.

Association between Socioeconomic Status and Hepatitis C Prevalence among Community-Dwelling Adults (전라남도 일지역 거주 성인의 사회경제적 지위와 C형 간염과의 관계)

  • Ahn, Hye-Ran;Jeong, Hyun-Ju
    • Journal of Korean Public Health Nursing
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    • v.31 no.2
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    • pp.234-243
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    • 2017
  • Purpose: This study was conducted to evaluate the socioeconomic status as a risk factor for hepatitis C virus infection among community-dwelling adults in Korea. Methods: This study was a cross-sectional study including 2,617 adults. Data from hepatocellular carcinoma epidemiological investigation and information regarding three markers of socioeconomic status, education, employment, household income, were obtained. Multiple logistic regression was performed to calculate odds ratios (ORs) for hepatitis C virus infection for socioeconomic status markers, adjusting for the other soioeconomic status marker, behavioral and hepatitis-related factors. Results: Of the 2,617 study subjects, 104 subjects infected with hepatitis C virus and prevalence was 4%. When compared to subjects with a lowest education, ORs was 0.16 (95% confidence interval [CI]: 0.04-0.69) for highest education group. After adjusting behavioral and hepatitis-related factors, ORs was 0.20 (0.05-0.87) for highest education compared with lowest group. Conclusion: Low educational level was associated with an increased risk of hepatitis C virus infection.

Component Analysis of Laryngeal Cancer Incidence Dynamics in Kazakhstan from 1999 to 2014

  • Zatonskikh, Vera;Igissinov, Nurbek;Igissinov, Saginbek;Igissinova, Gulnur;Bilyalova, Zarina;Kulmirzayeva, Dariyana;Venglovskiy, Anatoliy
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.9
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    • pp.4451-4456
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    • 2016
  • Background: In this study, we examined epidemiological aspects of dynamic changes in incidences of laryngeal cancer in male and female populations in Kazakhstan. Materials and Methods: Primary data were for registered patients with malignant laryngeal tumors in the whole country during the period of 1999-2014. Evaluation of changes in laryngeal cancer incidence in the population of Kazakhstan was performed using component analysis. Results: It was determined that the number of patients with laryngeal cancer in the whole country is decreasing although with conflicting impacts of different factors. Despite population growth (all - ${\Delta}_P=+66.1%$, men - ${\Delta}_P=+70.9%$ and women - ${\Delta}_P=+46.4%$), and aging (all - ${\Delta}_A=+45.1%$, men - ${\Delta}_A=+54.3$ and women - ${\Delta}_A=+22.2$), the reduction in risk of developing the disease (all - ${\Delta}_R=-165.6%$, men - ${\Delta}_R=-170.9%$ and women - ${\Delta}_R=-141.0%$) was overwhelming. Conclusions: This investigation was the first epidemiological study of dynamics of laryngeal cancer by component analysis in population of Kazakhstan. Implementation of the results of the study is recommended in management of anti-cancer activities for laryngeal cancer.

Status and Characteristics of Occurrence of Work-related Musculoskeletal Disorders (직업성 근골격계질환의 발생 현황과 특성)

  • Kim, Kyoo-Sang;Park, Jung-Keun;Kim, Day-Sung
    • Journal of the Ergonomics Society of Korea
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    • v.29 no.4
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    • pp.405-422
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    • 2010
  • Occupational musculoskeletal disorders currently account for the largest proportion of the occupational illnesses in Korea. In this research, status of musculoskeletal disorders among the occupational illnesses was examined through workers' compensation claims data. Types and characteristics of musculoskeletal disorders were looked at other data set as well. The data sets included epidemiological investigation data reported by Occupational Safety and Health Research Institute, and data collected from occupational disease surveillance reports and Korean occupational health-related scientific journals. Number of cases, incidence rate and insurance benefits for occupational musculoskeletal disorders in Korea are increasing every year. In addition, musculoskeletal disorders occurrence is shifted from large enterprises group to small-and-medium group, from manufacturing to service sector, and from production workers to office and professional workers. Although low back pain is still most common, its occurrence characteristics is gradually shifted from traumatic to cumulative while musculoskeletal disorders are somewhat seemingly moved from lumbar to upper limb body part. Musculoskeletal disorders were observed to be more diverse and prevalent in epidemiological investigations or surveillance data rather in workers' compensation claims data. Musculoskeletal disorders occurrence is related to demographic factors, occupational psychosocial factors, and ergonomic risk factors at workplace for which appropriate preventive measures needed to be made accordingly.

Gene-Diet Interaction on Cancer Risk in Epidemiological Studies

  • Lee, Sang-Ah
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.6
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    • pp.360-370
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    • 2009
  • Genetic factors clearly play a role in carcinogenesis, but migrant studies provide unequivocal evidence that environmental factors are critical in defining cancer risk. Therefore, one may expect that the lower availability of substrate for biochemical reactions leads to more genetic changes in enzyme function; for example, most studies have indicated the variant MTHFR genotype 677TT is related to biomarkers, such as homocysteine concentrations or global DNA methylation particularly in a low folate diet. The modification of a phenotype related to a genotype, particularly by dietary habits, could support the notion that some of inconsistencies in findings from molecular epidemiologic studies could be due to differences in the populations studied and unaccounted underlying characteristics mediating the relationship between genetic polymorphisms and the actual phenotypes. Given the evidence that diet can modify cancer risk, gene-diet interactions in cancer etiology would be anticipated. However, much of the evidence in this area comes from observational epidemiology, which limits the causal inference. Thus, the investigation of these interactions is essential to gain a full understanding of the impact of genetic variation on health outcomes. This report reviews current approaches to gene-diet interactions in epidemiological studies. Characteristics of gene and dietary factors are divided into four categories: one carbon metabolism-related gene polymorphisms and dietary factors including folate, vitamin B group and methionines; oxidative stress-related gene polymorphisms and antioxidant nutrients including vegetable and fruit intake; carcinogen-metabolizing gene polymorphisms and meat intake including heterocyclic amins and polycyclic aromatic hydrocarbon; and other gene-diet interactive effect on cancer.

Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation

  • Chang, Yeonhwa;Kim, Chanhee;Kim, Nayoung;Kim, Joon Jai;Lee, Heeyoung
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.5
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    • pp.370-375
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    • 2021
  • Objectives: The number of cases of hepatitis A virus (HAV) infections has sharply increased in Korea, especially among young adults. In this study, an HAV outbreak in a facility for disabled people was investigated, and we found epidemiological differences both between 2 different generations and between generally abled and disabled groups. Methods: We analyzed the incubation period and attack rate of an HAV outbreak and investigated the prevalence of HAV antibodies among the staff and residents of a facility for the disabled. We performed a retrospective cohort study during the HAV outbreak, which lasted from February 8 to 25, 2019, including examinations of HAV antibody tests and post-exposure HAV vaccination for the staff or residents of the facility. Results: There were 9 confirmed cases in 2 staff members and 7 residents. Among 53 people (30 staff and 23 residents), except for the 9 confirmed cases and 1 staff member with a known history of HAV infection, HAV seroprevalence was seen in 16.7% of the staff under 40 years of age and 95.2% of those over 40 years of age, while the corresponding rates in the residents were 0.0% and 58.8%, respectively. Conclusions: This result implies that it is necessary to prioritize HAV vaccination for vulnerable groups and workers of residential care facilities.