• Journal of Preventive Medicine and Public Health
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• 제51권6호
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• pp.265-274
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• 2018

Objectives: A positive association between air pollution and both the incidence and prevalence of diabetes mellitus (DM) has been reported in some epidemiologic and animal studies, but little research has evaluated the relationship between air pollution and diabetic coma. Diabetic coma is an acute complication of DM caused by diabetic ketoacidosis or hyperosmolar hyperglycemic state, which is characterized by extreme hyperglycemia accompanied by coma. We conducted a time-series study with a generalized additive model using a distributed-lag non-linear model to assess the association between ambient air pollution (particulate matter less than $10{\mu}m$ in aerodynamic diameter, nitrogen dioxide [$NO_2$], sulfur dioxide, carbon monoxide, and ozone) and emergency department (ED) visits for DM with coma in Seoul, Korea from 2005 to 2009. Methods: The ED data and medical records from the 3 years previous to each diabetic coma event were obtained from the Health Insurance Review and Assessment Service to examine the relationship with air pollutants. Results: Overall, the adjusted relative risks (RRs) for an interquartile range (IQR) increment of $NO_2$ was statistically significant at lag 1 (RR, 1.125; 95% confidence interval [CI], 1.039 to 1.219) in a single-lag model and both lag 0-1 (RR, 1.120; 95% CI, 1.028 to 1.219) and lag 0-3 (RR, 1.092; 95% CI, 1.005 to 1.186) in a cumulative-lag model. In a subgroup analysis, significant positive RRs were found for females for per-IQR increments of $NO_2$ at cumulative lag 0-3 (RR, 1.149; 95% CI, 1.022 to 1.291). Conclusions: The results of our study suggest that ambient air pollution, specifically $NO_2$, is associated with ED visits for diabetic coma.

• Tuberculosis and Respiratory Diseases
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• 제82권3호
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• pp.217-226
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• 2019

Background: Depression is a recognized complication of lung cancer underreported in developing countries such as Malaysia. Treating and identifying depression in cancer patients increases survival and quality of life. Our objectives are to study prevalence of depressive symptoms in newly diagnosed lung carcinoma, and examine the relationship of depressive symptoms with other influencing risk factors. Methods: A 2-year, cross sectional study February 2015-February 2017, was conducted at Hospital Tengku Ampuan Afzan, and Penang General Hospital. One hundred and three patients with newly diagnosed, biopsy confirmed primary lung carcinoma were recruited. Self-rated patient's identification sheet, validated Center for Epidemiologic Studies Depression (CES-D), and Dukes University Religion Index score from three different main languages were used. Results: Prevalence of current depressive symptoms (CES-D total score ${\geq}16$) is 37.9%. The result suggests prevalence of those at high risk of moderate to major depression, may need treatment. Multivariate analysis reveals those with good Eastern Cooperation Oncology Group factor (${\eta}2=0.24$, p<0.001) married (${\eta}2=0.14$, p<0.001) with intrinsic religiosity (IR) (${\eta}2=0.07$, p<0.02) are more resistant to depression. Conclusion: One in three of lung carcinoma patients, are at increased risk for depression. Clinicians should be aware that risk is highest in those with poor performance status, single, and with poor IR. We suggest routine screening of depression symptoms as it is feasible, to be performed during a regular clinic visit with immediate referral to psychiatrist when indicated.

• 한국콘텐츠학회논문지
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• 제22권2호
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• pp.411-419
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• 2022

본 연구에서는 위험회피 기질을 가진 대학생들이 우울에 취약하다는 점을 확인하면서 그 과정에 정서표현 양가성과 고통 감내력이 매개변인으로서 영향을 미친다는 점을 검증해보는 데 목적이 있다. 403명의 대학생들을 대상으로 TCI-RS, AEQ-K, DTS, CES-D를 실시하였다. 분석 결과, 위험회피 기질과 정서표현 양가성은 우울과 유의한 정적 상관을, 고통 감내력과는 부적 상관을 보였다. 또한, 정서표현 양가성과 고통 감내력은 위험회피 기질을 순차적으로 매개하여 우울에 간접적으로 영향을 미치는 것으로 나타났다. 즉, 기질적 특성뿐만 아니라 심리사회적 요인이 복합적으로 우울에 영향을 미치고 있음을 시사한다.

• 대한간호학회지
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• 제53권1호
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• pp.12-27
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• 2023

Purpose: This study aimed to develop a scale to measure distress in patients with ischemic stroke and verify its validity and reliability. Methods: Preliminary items were developed from literature review and in-depth interviews. The final preliminary scale was confirmed through a content validity test of eight experts and a preliminary survey of 10 stroke patients. The participants for psychometric testing were 305 stroke patients in the outpatient clinic. Validity and reliability analyses included item analysis, exploratory and confirmatory factor analysis, convergent validity, known-group validity, and internal consistency of the scale. Results: The final scale consisted of 17 items and 3 factors. The three distinct factors were 'self-deprecation, worry about future health, and withdrawal from society' and this structure was validated using a confirmatory factor analysis. Convergent validity was supported by comparison with the Center for Epidemiologic Studies Depression Scale (r = .54, p < .001) and Brief Illness Perception Questionnaire (r = .67, p < .001). Known-groups validity was verified by dividing groups according to 'duration since diagnosis' (t = 2.65, p = .009), 'presence of sequela' (t = 10.16, p < .001), and 'awareness of distress' (t = 12.09, p < .001). The internal consistency of the scale using Cronbach's α for the total items was .93. Conclusion: The Ischemic Stroke Distress Scale is a valid and reliable tool that reflects stroke distress effectively. It is expected to be used as a basic tool to develop various intervention strategies to reduce distress in ischemic stroke patients.

• Archives of Plastic Surgery
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• 제50권1호
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• pp.37-41
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• 2023

Background The coronavirus disease 2019 (COVID-19) outbreak has had a major impact worldwide. Several countries have implemented restrictions on social interaction ("social distancing"). Several studies have reported that the epidemiology of trauma patients, such as those with facial bone fractures, has changed after COVID-19 pandemic. This study aimed to further explore these specific changes. Methods This was a retrospective study of patients who presented to a single institution with facial bone fractures between January 1, 2016, and December 31, 2020. Baseline patient demographics, clinical information, type of fracture, etiology, and operative management were compared before and after COVID-19. Results Of all cases, 3,409 occurred before COVID-19, and 602 occurred after COVID-19. Since the outbreak of COVID-19, the number of patients with facial fractures has not decreased significantly. A significant increase was noted in fractures that occurred outdoors (p < 0.001). However, a decrease was observed in operative management between the groups (p < 0.001). There was no significant difference in the proportion of assault, fall-down, industrial accident, or roll-down. In contrast, the proportion of traffic accidents and slip-down categories increased significantly (p < 0.05). Moreover, a significant decrease was found in the proportion of the sports category (p = 0.001) Conclusions It was confirmed through this study that COVID-19 pandemic also affected epidemiology of facial fractures. Focusing on these changes, it is necessary to develop safety measures to reduce facial fractures.

• 한국엔터테인먼트산업학회논문지
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• 제13권7호
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• pp.431-440
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• 2019

본 연구는 대학생이 지각한 부모의 과보호와 우울 증상에 미치는 영향에서 회피대처의 조절효과를 규명하고자 한 연구이다. 연구 대상은 지방 지역의 대학생 230명을 대상으로 자기보고식 설문조사를 실시하였다. 본 연구에 사용된 측정도구는 부모양육태도, 우울, 회피대처의 척도였다. 분석방법은 SPSS 21.0 통계프로그램을 이용하여 빈도와 백분율을 산출하였고, 내적합치도 계수(Cronbach α)를 구하였다. 본 연구문제를 검증하기 위해 상관분석과 위계적 중다회귀분석을 실시하였고, 밝혀진 결과를 요약하면 다음과 같다. 첫째, 부모의 과보호와 우울증상, 회피대처는 각 변인 간 모두 정적상관을 나타냈다. 둘째, 부모의 과보호와 우울증상의 관계에서 회피대처는 조절효과를 주는 변인임을 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2401-2405
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• 2016

Background: Both colorectal cancer (CRC) and diverticular disease (DD) are common in the affluent West, and their prevalence is also increasing in the rest of the world with economic development. Both diseases have common epidemiologic characteristics; increasing incidence, more common with advancing age and related to specific dietary changes. However, studies of associations between the two have generated mixed results with some showing positive correlations, whilst others have shown no or negative links. Most of these studies have been from the West with study populations that were predominantly Caucasians. Here the focus was on DD and colorectal neoplasms, including CRC, in Brunei. Materials and Methods: All patients who had undergone complete colonoscopy between 2011 and 2014 were identified and retrospectively reviewed. Patients under the age of 18 years old or had previous colonic surgeries (including previous CRC resection) were excluded. Results: The total number of colonoscopies included in the study was 2,766 (mean age $53.2{\pm}14.8$ years old, male 51.8%), of which DD, CRC and colonic polyps were detected in 17.3%, 4.7% and 28.2% respectively. The proportions of DD, polyps and CRC increased proportionally with age (<30 years, 30-49, 50-69 and ${\geq}70$). Overall, there was no association between the presence of DD and CRC (3.6% vs. 5.0%, p=0.179) but there was a significant association between CRC and left sided DD (p=0.034 by trend). There were also a significant association between presence of DD and polyps (36.1% vs. 28.2%, p=0.001), in particular with right-sided and pan-DD (p=0.001 for trend). Conclusions: Our study showed that the prevalence of DD, CRC and polyps increases with age. There were significant associations between presence of left-sided DD with CRC and right-sided or pan-DD with colonic polyps. This suggests shared risk factors. Further studies are required to assess links in other countries of the Asian Pacific region.

• Journal of Preventive Medicine and Public Health
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• 제34권2호
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• pp.103-108
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• 2001

대기분진의 영향을 분석한 역학적 연구들은 분석방법의 오류, 생물학적인 타당성, 혼란변수의 통제 등 여러 가지 제한점들을 갖고 있기 때문에 이를 해석할 때 주의를 요한다. 그러나 대기분진역학연구들이 여러 가지 다른 연구방법과 자료원, 그리고 분석기법 등을 적용하였는데도 불구하고 연구결과간에 일치성이 매우높기 때문에 대기분진의 인체효과에 대한 연구결과가 일정한 방법론적인 또는 분석상의 오류에 의해서 나타났을 가능성은 거의 없다. 역학적 연구들이 생물학적인 타당성에 대한 상세한 근거를 제시하기는 어렵지만 서로 다른 연구들의 결과가 호흡기질환 및 심혈관계질환에 대한 건강영향을 나타내고 있으나 기타 질환에 대해서는 의미있는 결과들이 거의 없다는 것은 대기분진이 호흡기질환 및 심혈관계질환에 미치는 생물학적인 기전의 근거를 강하게 나타낸다고 할 수 있다. 대기분진 역학연구의 또 다른 중요한 관심사는 혼란변수의 통제 문제이다. 혼란변수란 노출과 질병에 서로 연관되어 있는 다른 위험인자가 분석에서 적절하게 통제되지 못하였을 때 이로 인하여 대기분진과 건강영향의 관련성이 잘못 나타나는 것을 말한다. 그러나 역시 서로 다른 연구들에서 여러 가지 혼란변수가 관련성에 영향을 미쳤다면 여러 지역의 다양한 연구에서 일정한 결과를 제시하기는 어려웠을 것이므로 대기분진과 건강영향의 관련성이 혼란변수의 부적절한 처리 때문에 나타난 것이라고 보기는 어렵다. 물론 대기분진 이외의 가스상 오염 물질이 같이 존재하고 또 서로간의 상관성이 매우 높기 때문에 이러한 대기오염 물질의 영향을 완전히 통제한 상태에서 대기분진만의 영향을 관찰한다는 것은 매우 어려운 일이다. 따라서 다중 공선성의 문제나 교차효과의 문제 등이 앞으로 대기분진 역학연구의 과제일 것이다. 결론적으로, 대기분진이 사망률 및 병원 내원율 등에 미치는 영향은 확립되었다고 보아도 될 것이다. 또한 우리나라의 연구들을 통하여 대기분진의 건강영향은 예외 없이 우리에게도 나타나는 문제라는 것을 확인하였다. 그러나 이러한 역학적 관련성에 대한 성과에도 불구하고 발생기전의 평가, 감수성 인구집단의 확인, 예방 및 관리 대책 마련 등 앞으로 해야 할 과제가 많이 남아있다.

• Journal of Preventive Medicine and Public Health
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• 제42권2호
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• pp.82-88
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• 2009

Objectives : Our objective was to examine and evaluate the psychological health of the residents of Taean during the cleanup of the Hebei Spirit(HS) oil spill and to review some factors associated with the results. Methods : A community survey of 71 men and women was conducted 8 weeks after the HS oil spill. Questionnaires used were the PWI(Psychological Well-being Index) scale for psychosocial distress, the CES-D(Center for Epidemiologic Studies-Depression) scale for depressive symptoms, and a questionnaire created to assess suicidal impulses. Results : The overall prevalence of high-risk psychosocial distress among the study group was 64.2%. The percentages of respondents with scores on the CES-D Scale above 16 and above 21 were 77.6% and 62.7%, respectively. The percentage of respondents categorized as having suicidal impulses was 18.3%. When compared with unexposed groups in the general population taken from various sources, the residents of Taean were 6.5 times as likely to have high stress and 9.4-9.7 times as likely to be depressed. No significant difference in the rate of suicidal impulse was found between the residents of Taean and the general population. Factors associated with high stress, depression, and suicidal impulses were age, a change in income, educational level, number of days working on the cleanup, and positive responses to questions about "affected daily activity" and "hospital visit due to work on cleanup". Conclusions : The results suggest that the HS oil spill had a significant impact on the psychological health of residents of Taean, but the comparability of the unexposed groups is a limitation of the study.

• Safety and Health at Work
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• 제4권3호
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• pp.142-148
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• 2013

Background: To elucidate the relationship between seven occupational dermatoses (ODs) and 20 types of work in Greece. Methods: This was a prevalence epidemiologic study of certain ODs among 4,000 workers employed in 20 types of enterprise, in 104 companies, in 2006-2012, using data from company medical records, questionnaires, occupational medical, and special examinations. The ${\chi}^2$ test was applied to reveal statistically significant relationships between types of enterprises and occurrence of ODs. Results: A high percentage (39.9%) of employees included in the study population suffered from ODs. The highest prevalence rates were noted among hairdressers (of contact dermatitis: 30%), cooks (of contact dermatitis: 29.5%), bitumen workers (of acne: 23.5%), car industry workers (of mechanical injury: 15%), construction workers (of contact urticaria: 29.5%), industrial cleaning workers (of chemical burns: 13%), and farmers (of malignant tumors: 5.5%).We observed several statistical significant correlations between ODs (acute and chronic contact dermatitis, urticaria, mechanical injury, acne, burns, skin cancer) and certain types of enterprises. There was no statistically significant correlation between gender and prevalence of ODs, except for dermatoses caused by mechanical injuries afflicting mainly men [${\chi}^2(1)=13.40$, p < 0.001] and for chronic contact dermatitis [${\chi}^2(1)=5.53$, p=0.019] afflicting mainly women. Conclusion: Prevalence of ODs is high in Greece, contrary to all official reports by the Greek National Institute of Health. There is a need to introduce a nationwide voluntary surveillance system for reporting ODs and to enhance skin protection measures at work.