• 제목/요약/키워드: Epidemic

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HbA1C value and Pre-diabetes Early Detection in the Independent Community Pharmacy

  • Oh, C.T.
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.72.2-72.2
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    • 2003
  • Lifestyle change in the world is spawning an epidemic of Global Obesity. (Newsweek August 11. 2003) People with overweight are at great risk of developing Type II diabetes. The A1C value provides an objective assessment of glucose control over the previous six to eight weeks. The American Diabetes Association recommended values for blood glucose and A1C appear in TABLE 4. In case one who was found to have >7% HbA1C, he(she) may be a patient with pre-DM or DM II. (omitted)

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Field Control of Phytophthora Blight of Pepper Plants with Antagonistic Rhizobacteria and DL-$\beta$-Amino-n-Butyric Acid

  • Lee, Jung-Yeop;Kim, Beom-Seok;Lim, Song-Won;Lee, Byung-Kook;Kim, Choong-Hoe;Hwang, Byung-Kook
    • The Plant Pathology Journal
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    • 제15권4호
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    • pp.217-222
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    • 1999
  • Treatment with antagonistic rhizobactera Burkholderia cepacia strain N9523 or an inducer of resistance DL-$\beta$-amino-n-butyric acid (BABA) effectively inhibited Phytophthora capsici infection on pepper plants in artificially infested pots. Treatment with BABA alone at $1,000\mu\textrm{g}$/ml or together with B. cepacia in combination induced a strong protection from the Phytophthora disease in the greenhouse. In artificially infested field, protection of pepper plants against the Phytophthora epidemic by BABA treatment was maintained at a considerable level. In contrast, soil drench with the antagonist B. cepacia alone, or in combination with BABA did not suppress the Phytophthora epidemic in the field. Mortality of pepper plants caused by P. capsici infection was significantly reduced by treatment with the antagonist Pseudomonas aeruginosa strain 950923-29 and BABA (12-29% plants diseased) relative to the untreated control (41-91% plants diseased) in the naturally infested field. Treatment with the antagonist Ps. aeruginosa strain 950923-29 and BABA also resulted in high levels of protection against Phytophthora blight in pepper plants. In the plastic filmhouse test, the average percentage of plants diseased was significantly low relative to the naturally infested field. Treatment with the antagonist Ps. aeruginosa strain 950923-29 and BABA in combination was most effective in suppressing the Phytophthora disease in field and plastic filmhouse.

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돼지 유행성 설사 바이러스 국내분리주의 유전학적 특성 규명 (Genetic Characteristics of Porcine Epidemic Diarrhea Virus Isolated in Korea)

  • 지영철;권혁무;정현규;한정희
    • 대한수의학회지
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    • 제43권2호
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    • pp.219-230
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    • 2003
  • Porcine epidemic diarrhea virus(PED), a member of Coronaviridea, is the etiological agent of enteropathogenic diarrhea in swine. The purpose of this study was to investigate genetic characteristic of PEDV isolated in Korea. Nucleocapsid(N) gene and membrane (M) gene of recent Korean PEDV strains isolated in 2001 were amplified, cloned, sequenced and analyzed. N gene of seven Korean PEDV field isolates bad 94.5% to 99.4% nucleotide and 92.4% to 99.4% amino acid sequence homology each other. Nucleotide and amino acid sequences of Korean field PEDVs were different from published foreign PEDVs, showing 95.1% to 98.0% nucleotide and 93.5% to 97.6% amino acid sequence homology. By phylogenetic tree analysis on based nucleotide sequences, PEDVs were clustered into four groups. By phylogenetic tree analysis based on amino acid sequences. PEDVs were clustered into five groups. M gene of our Korean PEDV field isolates had 99.6% to 100% nucleotide and 98.7% to 100% amino acid sequence homology each other. Nuclotide and amino acid sequences of Korean field PEDVs were different from published foreign PEDVs, showing 98.5% to 98.8% nucleotide and 97.3% to 97.8% amino acid sequence homology. By phylogenetic tree analysis based on nucleotide and amino acid sequences, PEDVs were clustered into two groups which were Korean PEDV isolate group and foreign PEDV isolate group.

Yemen's Cholera Epidemic Is a One Health Issue

  • Ng, Qin Xiang;Deyn, Michelle Lee Zhi Qing De;Loke, Wayren;Yeo, Wee Song
    • Journal of Preventive Medicine and Public Health
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    • 제53권4호
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    • pp.289-292
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    • 2020
  • Yemen has been faced with the worst cholera epidemic of modern times, with more than 1 million suspected cases and 3000 deaths at the time of writing. This problem is largely due to the longstanding civil war between pro-government forces and the Houthi armed movement, which has severely damaged already vulnerable sanitation and healthcare facilities and systems in the country. It is further compounded by a dire lack of basic amenities, chronic malnutrition, and unfavourable weather conditions. Another contributory component may be aerial transfer by cholera-infected chironomid insects. To contain the spread of cholera in Yemen, a nation-wide armistice should be negotiated, and national and local committees must be convened to coordinate efforts on the ground. Community isolation facilities with proper sanitation, reliable disposal systems, and a clean water supply should be set up to isolate and treat sick patients. The continuity of vaccination programmes should be ensured. Public health campaigns to educate local communities about good hygiene practices and nutrition are also necessary. The One Health paradigm emphasizes a multi-sectoral and transdisciplinary understanding and approach to prevent and mitigate the threat of communicable diseases. This paradigm is highly applicable to the ongoing cholera crisis in Yemen, as it demands a holistic and whole-of-society approach at the local, regional, and national levels. The key stakeholders and warring parties in Yemen must work towards a lasting ceasefire during these trying times, especially given the extra burden from the mounting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak worldwide.

MMR 2차 예방접종을 받은 후 이하선염 없이 발생한 볼거리 뇌염 1례 (Mumps meningoencephalitis without parotitis, after secondary vaccination of Measles-Mumps-Rubella (MMR) : A Case Report)

  • 최판규;강현구
    • 한국산학기술학회논문지
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    • 제18권9호
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    • pp.123-126
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    • 2017
  • 볼거리(mumps)는 유행선 이하선염(epidemic parotitis)으로 불리며, 볼거리 바이러스에 의해 유발되는 바이러스성 감염질환이다. 볼거리는 췌장염, 고환염, 청력장애, 난소염, 이하선염 및 뇌수막염과 같은 합병증을 일으킬 수 있다. 볼거리로 인한 중추신경계의 침범은 볼거리로 진단된 환자의 65%에 달한다는 보고가 있으며, 그 중 대부분은 볼거리 뇌막염(mumps meningitis)이다. 이에 반해 볼거리 뇌염(mumps meningoencephalitis)은 볼거리 환자 6000명당 1명의 경우로 매우 드물다고 알려져 있다. 뇌염은 볼거리바이러스의 흔하지 않은 중추신경계의 합병증으로 홍역-볼거리-풍진 예방접종은 볼거리바이러스로 인한 치명적인 합병증을 예방해주고 경과를 가볍게 해준다고 알려져 있다. 저자들은 24세의 젊은 여자가 이하선염을 동반하지 않은 볼거리 바이러스로 인한 급성 뇌염을 경험하여 이에 대한 사례 연구를 하였다. 환자는 예방접종 시기에 맞춰 볼거리 예방접종을 받았다. 본 병원을 내원 시 환자는 인지능력의 저하를 보였으며 치료 후 빠른 회복을 보였고 합병증은 보이지 않았다. 이 연구는 볼거리 바이러스에 대한 2차 접종을 시기에 맞춰 받은 환자에서 이하선염의 동반 없이 뇌염증상이 발생한 환자에 대한 사례 연구이다.

신종플루 유행에 대한 보건소 담당자의 대응평가와 관련 요인 (Responsiveness of Public Health Center and Its Related Factors against H1N1 Epidemic)

  • 장정랑;김건엽;홍남수;감신;이원기;이유미
    • 보건행정학회지
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    • 제23권1호
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    • pp.52-58
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    • 2013
  • This study was conducted to investigate the responsiveness and its related factors of public health center for novel influenza A (H1N1) epidemic. The data was collected through a web-based survey conducted during February to April 2011. The 182 respondents were team leaders or persons who were responsible for H1N1-related work at public health centers during the H1N1 prevalence. The related factors affecting the responsiveness were different by urban or rural area. In the level of gu (urban) area, cooperation with the public organizations, preparing its own response plan were the significant factors. But, in the level of si or gun (rural) area, cooperation with private organizations (clinic or pharmacy), physical (facilities, equipments, and medicines), and human infrastructures (public health professions, education and knowledge, and motivation) were more important factors. Therefore, how to cope with H1N1 prevalence in the future should be different by local characteristics. As a result, there are several challenges that public health centers should prepare for the further emerging infectious diseases. First, it is needed to make standard manuals which could strengthen education and training in order to respond appropriately, as well as to prepare enough physical infrastructures for the crisis. Next, the public health center should prepare correct media response and cooperation system with public and private organizations.

Comparison of PFGE, IS6110-RFLP, and 24-Locus MIRU-VNTR for Molecular Epidemiologic Typing of Mycobacterium tuberculosis Isolates with Known Epidemic Connections

  • Jeon, Semi;Lim, Nara;Park, Sanghee;Park, Misun;Kim, Seonghan
    • Journal of Microbiology and Biotechnology
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    • 제28권2호
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    • pp.338-346
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    • 2018
  • Two molecular epidemiologic methods, IS6110 restriction fragment length polymorphism (IS6110-RFLP) and 24-locus mycobacterial interspersed repetitive unit-variable-number tandem repeat (MIRU-VNTR), are used worldwide in studies of Mycobacterium tuberculosis (MTB). Conversely, because of its poor resolution, pulsed-field gel electrophoresis (PFGE) is not widely used for MTB. In this study, we improved the 24-locus MIRU-VNTR and PFGE protocols and compared the effectiveness of these approaches for the molecular typing of MTB using 75 clinical isolates obtained from a cohort investigation of high-risk populations infected with MTB. The 24-locus MIRU-VNTR method demonstrated superior discriminatory ability, followed by PFGE and IS6110-RFLP. Next, we analyzed six isolates with clear epidemiologic connections; that is, isolates from patients who attended the same school. IS6110-RFLP and PFGE identified these samples as the same type. By contrast, according to MIRU-VNTR, two isolates differed from four other isolates at one locus each; one isolate was identified as Mtub29 and the other as QUB-26. In summary, the 24-locus MIRU-VNTR assay was the most useful molecular typing method among the three methods investigated due to its discriminatory power, short time required, and availability as an epidemiologic investigation tool. PFGE was the second-best method. Compared with the other loci assessed in the 24-locus MIRU-VNTR assay, the Mtub29 and QUB-26 loci appeared to exhibit greater variability during transmission.

Towards a Dialogic Approach: Crisis Communications and Public Reactions in the World's Most Densely Populated City to Tackle COVID-19

  • Yuncg, Juliana Qi Xuan;Cheong, Angus Weng Hin;Seng, Athena I No;Li, Kim Jing
    • Asian Journal for Public Opinion Research
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    • 제8권3호
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    • pp.265-296
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    • 2020
  • Macao, a special administrative region of China, has been able to maintain the records of zero deaths and keep confirmed cases under 50 since the outbreak of COVID-19 for more than half a year as of July 2020, despite being the world's most densely populated city. The current paper utilizes the dialogic public relations theory to analyze the situation using both literature review on how the various government actions and strategies during the pandemic were corresponding to the theory, and a quantitative random digital dialing (RDD) telephone survey, with a sample of 502 Macao residents aged 18 or above, to study the public reactions towards the government pandemic prevention actions. Survey results show a high level of public satisfaction towards epidemic prevention performance, as well as some forms of collaborative information redissemination behavior in social media platforms. Literature review and analysis from dialogic theory found that spirit of mutual equality, collaboration with local community, immediacy of presence in crisis time, engagements with stakeholders through maximum media channels and networks, supportiveness to public with both useful information and practical social support like subsidy program, as well as commitment to transparent and genuine communication, are all the dialogic communications strategies that describe what the Macao government has done in the crisis of COVID-19. The dialogic strategies that could be learned from the Macao government may be used as a reference for similar urbanized and densely populated cities in other territories.