• Journal of Radiation Protection and Research
• /
• v.9 no.2
• /
• pp.118-128
• /
• 1984

The analysis of radiological protection at Kori Nuclear Unit #1, which started commercial operation on April 29, 1978, has been carried out in three areas, namely, radiation exposure, radioactive waste disposal and environmental management. The analysis results for radiation exposure and radioactive effluent releases appear to increase gradually with plant operating years. On the other hand, the apex of radiation exposure and radioactive effluent releases was in 1983 and 1982 respectively and then decreased or stabilized. Also, the operation environmental radioactivity seems to be no higher than preoperation environmental radioactivity.

• Journal of Korean Society on Water Environment
• /
• v.29 no.6
• /
• pp.842-846
• /
• 2013

In 2012, the Korean Ministry of Environment (MOE) added 3 new water quality standards for the protection of human health; specifically, regarding 1,4-dioxane, formaldehyde, and hexachlorobenzene. In this study, we assimilated the water quality standards of these 3 substances from other countries, with respect to surface water quality standards for human health protection and drinking water standards. We subsequently investigated how these standard values were derived. 1,4-Dioxane is managed as an environmental standard for human health in Japan, and as a drinking water quality standard in WHO, New Zealand, and Japan with respect to both carcinogenic and non-carcinogenic effects. In New York, the oncogenic effects of formaldehyde in drinking water intake is considered, whereas WHO, Australia, New Zealand, and Japan also assess the non-carcinogenic effects of formaldehyde when setting their standards. USEPA and New York have a water quality standard for human health protection with respect to hexachlorobenzene based on carcinogenic effects. This study focuses on deriving water quality standards for the 3 new substances, or obtaining baseline information to revise the values of existing substances in the future.

• Journal of Advanced Marine Engineering and Technology
• /
• v.38 no.10
• /
• pp.1212-1216
• /
• 2014

This study aims to find out the best anode location for buried pipelines. Numerical simulation program known as CATPRO (Elsyca, Belgium) were used for confirming the best location of anodes and the effects of impressed current cathodic protection system. Applied conditions for numerical simulation were similar to on-site environmental conditions for optimal application of cathodic protection system. Used criterion of cathodic protection was NACE SP 0169, which describes that minimum requirement for cathodic protection is -850mV vs. CSE. Various layouts for anodes' installation were applied, which were distance between anodes, anode installation location, and applied current. The areas where cathodic protection potential was lower than -850mV vs. CSE was limited up to 50m from anode installation locations. It was founded numerical analysis obtain cost-effective and efficient cathodic protection methods before design and application the impressed cathodic protection system to on-site environment.

• Journal of Korean Society of Rural Planning
• /
• v.6 no.2 s.12
• /
• pp.94-105
• /
• 2000

The purpose of this study were to make a comparison with the level of environmental consciousness between the livestock farmer and the reference groups( peasant, office worker, housewife and student) and to identify the variables which have an influence on the level of their role performance for environmental protection & preservation. Data for this study were collected from 822 cases including the livestock farmer(109), the peasant(67), the office worker(140), the housewife(119) and the student(356). The SPSS software program and statistics such as frequencies, x2, ANOVA, multiple regression analysis, Chronbach's ${\alpha}$ and factor analysis were used to analyze the data for this study. The major findings of this study were as follows: 1. The pro-environmental attitude score(environmental sensitivity and attitude of environmental protection & preservation) the groups of office worker and housewife is shown higher than the groups of livestock farmer, peasant and student. 2. The consciousness of environmental problem is relatively low to the group of the livestock farmer compared with the reference groups. 3. As a result of multiple regression analysis, four determinants such as locus of control, lifestyle, environmental sensitivity, and knowledge of environmental issues explained 38.8% of the livestock farmer's role performance for the environmental protection & preservation.

• Journal of Environmental Policy
• /
• v.12 no.2
• /
• pp.33-57
• /
• 2013

This paper test the relationship among determinants of environmental investments, level of environmental investments, eco-efficiency (carbon productivity). The results show that profitability, leverage and R&D costs have a negative impact on environmental investments, and controlling ownership have a positive impact on environmental investments as well as environmental protection costs. The analysis also show that firms increasing environmental investments are able to gain superior environmental performance ($CO_2$ emission), but are negatively relationship with financial performance. Finally, the findings prove that differences exist in the relationship between determinants and effect of environmental investments when grouped by industry characteristics.

• Proceedings of the KSEEG Conference
• /
• 2002.04a
• /
• pp.11-13
• /
• 2002

• Proceedings of the Korea Society of Environmental Toocicology Conference
• /
• 1998.12a
• /
• pp.84-84
• /
• 1998

• Bulletin of Korea Environmental Preservation Association
• /
• v.21 no.7_8
• /
• pp.25-43
• /
• 1999

• Proceedings of KOSOMES biannual meeting
• /
• 2000.05a
• /
• pp.53-66
• /
• 2000

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.18
• /
• pp.8503-8512
• /
• 2016

The purpose of this study was to provide a detailed explanation of the mechanism of bisanthracycline, WP 631 in comparison to doxorubicin (DOX), a first generation anthracycline, currently the most widely used pharmaceutical in clinical oncology. Experiments were performed in SKOV-3 ovarian cancer cells which are otherwise resistant to standard drugs such as cis-platinum and adriamycin. As attention was focused on the ability of WP 631 to induce apoptosis, this was examined using a double staining method with Annexin V and propidium iodide probes, with measurement of the level of intracellular calcium ions and cytosolic cytochrome c. The western blotting technique was performed to confirm PARP cleavage. We also investigated the involvement of caspase activation and DNA degradation (comet assay and immunocytochemical detection of phosphorylated H2AX histones) in the development of apoptotic events. WP 631 demonstrated significantly higher effectiveness as a pro-apoptotic drug than DOX. This was evident in the higher levels of markers of apoptosis, such as the externalization of phosphatidylserine and the elevated level of cytochrome c. An extension of incubation time led to an increase in intracellular calcium levels after treatment with DOX. Lower changes in the calcium content were associated with the influence of WP 631. DOX led to the activation of all tested caspases, 8, 9 and 3, whereas WP 631 only induced an increase in caspase 8 activity after 24h of treatment and consequently led to the cleavage of PARP. The lack of active caspase 3 had no outcome on the single and double-stranded DNA breaks. The obtained results show that WP 631 was considerably more genotoxic towards the investigated cell line than DOX. This effect was especially visible after longer times of incubation. The above detailed studies indicate that WP 631 generates early apoptosis and cell death independent of caspase-3, detected at relatively late time points. The observed differences in the mechanisms of the action of WP631 and DOX suggest that this bisanthracycline can be an effective alternative in ovarian cancer treatment.