• Title/Summary/Keyword: Enhance Effect

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Effect of Graphitic Nanofibers on Interfacial Adhesion and Fracture Toughness of Carbon Fibers-reinforced Epoxy Composites

  • Kim, Seong-Hwang;Park, Soo-Jin
    • Composites Research
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    • v.34 no.2
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    • pp.82-87
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    • 2021
  • The mechanical properties of carbon fiber-reinforced epoxy composites (CFRPs) are greatly dependent on the interfacial adhesion between the carbon fibers and the epoxy matrix. Introducing nanomaterial reinforcements into the interface is an effective approach to enhance the interfacial adhesion of CFRPs. The main purpose of this work was to introduce graphitic nanofiber (GNFs) between an epoxy matrix and carbon fibers to enhance interfacial properties. The composites were reinforced with various concentrations of GNFs. For all of the fabricated composites, the optimum GNF content was found to be 0.6 wt%, which enhanced the interlaminar shear strength (ILSS) and fracture toughness (KIC) by 101.9% and 33.2%, respectively, compared with those of neat composites. In particular, we observed a direct linear relationship between ILSS and KIC through surface free energy. The related reinforcing mechanisms were also analyzed and the enhancements in mechanical properties are mainly attributed to the interfacial interlocking effect. Such an effort could accelerate the conversion of composites into high performance materials and provide fundamental understanding toward realizing the theoretical limits of interfacial adhesion and mechanical properties.

Effect of Vitamin E Treatments on The Humoral and Cellular Immune Responses in Mice. - Animal experiment for nursing care of vitamin E-deficient patients- (비타민 E 투여가 마우스의 체액성 및 세포성 면역반응에 미치는 영향 -비타민 E 결핍환자의 간호중재 개발을 위한 동물실험 -)

  • 김금재
    • Journal of Korean Academy of Nursing
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    • v.23 no.4
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    • pp.528-543
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    • 1993
  • Vitamin E, which has its advocates in the treatment of diabetes mellitus. autoimmune disease, cancer and peripheral vascular and thromboembolic disease, has now been alleged to have a powerful antioxident effect and to affect various biological activities such as fertility factor, inhibition of human platelet aggregation and stabilization of biological membranes. The present study was designed to test whether vitamin I(alpha-tocopherol) can : (1) enhance the hemagglutinin response to sheep red blood cells (SRBC), (2) modulate Arthus and delayed type hypersensitivity(DTH) to SRBC and contact hypersensitivity to dinitrofluorobenzene (DNFB). (3) enhance the mitogenic response of murine splenocyte, (4) decrease the recovery of Cryptococcus neoformans from brain, lung, liver, spleen and kidney of infected mice and (5) have an inhibitory or enhancing effect on the induction of active systemic anaphylaxis(ASA) induced by chicken-gamma globulin (CGG) in mice. Mice were given either intramuscular injections of 0.3ml (300mg) of vitamin I before immunization or were infection for 10 consecutive days or were given by vitamin I esophageal intubation, 0.1ml(100mg), for 20 days before sacrifice for the mitogenic response experiments. It was found that vitamin E treated mice showed a significant enhancement in hemagglutinin response, Arthus reaction and DTH to SRBC and contact hypersensitivity to DNFB. There was no significant difference in the mitogenic response to phytohemagglutinin(PHA), but the response to concanavalin A(ConA) or pokeweed mitogem(PWM) was increased in vitamin E-treated mice. Interestingly, the vitamin E administration before C. neoformans infection decreased significantly the recovery of C. neoformans from brain lung, liver, spleen and kidney of the infected mice as compared with that of the control mice, strongly suggesting that vitamin E pretreatment may increase the resistance of mice to the fungal infection. Unexpectedly, vitamin E administration enhanced the production of CGG -induced ASA. Taken together, it can be concluded that vitamin I administration may in-crease the humoral and cellular immune response and resistance. to C. neoformans infection, but enhance the induction of ASA to CGG. Further studies are necessary to clarify the underlying mechanism accounting for these effects.

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The Effect of Green Tea Powder on Yackwa Quality and Preservation (녹차분말 첨가가 약과의 품질과 저장성에 미치는 영향)

  • Yun, Geun-Young;Kim, Myoung-Ae
    • Journal of the Korean Society of Food Culture
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    • v.20 no.1
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    • pp.103-112
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    • 2005
  • The objective of this study was to clarify the effect of addition of green tea powder(0%, 2%, 4%, 6%, 8%) to Yackwa on quality and preservation. Addition of 4% green tea powder turned out to give positive effect on expansion. In test of physical characters, addition of green tea powder had a tendency to lower hardness, cohesiveness, springness and gumminess but to enhance brittleness. Considering the rancidity of oil within Yackwa, addition of green tea powder tended to show lower acid value and peroxide value than non-added treatment but its difference was slight. At the sensory test, surface color, bitterness and green tea flavor were strong but sweet and savory taste weak when green team powder was added(p<0.05). Overall quality appeared to have improved to 5.55 points which is compared to non-addition when the powder was added 4%(p<0.05). In conclusion, 4% addition of green tea powder would be the usefull method to enhance preference and quality of Yackwa.

Capsaicin-Induced Apoptosis and Reduced Release of Reactive Oxygen Species in MBT-2 Murine Bladder Tumor Cells

  • Lee, Ji-Seon;Chang, Jong-Sun;Lee, Ji-Youl;Kim, Jung-Ae
    • Archives of Pharmacal Research
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    • v.27 no.11
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    • pp.1147-1153
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    • 2004
  • Bladder cancer is a common cancer with high risk of recurrence and mortality. Intravesicle chemotherapy after trans-urethral resection is required to prevent tumor recurrence and progression. It has been known that antioxidants enhance the antitumor effect of bacillus Calmette-Guerin (BCG), the most effective intravesical bladder cancer treatment. Capsaicin, the major pungent ingredient in genus Capsicum, has recently been tried as an intravesical drug for overactive bladder and it has also been shown to induce apoptotic cell death in many cancer cells. In this study, we investigated the apoptosis-inducing effect and alterations in the cellular redox state of capsaicin in MBT-2 murine bladder tumor cells. Capsaicin induced apoptotic MBT-2 cell death in a time- and dose-dependent manner. The capsaicin-induced apoptosis was blocked by the pretreatment with Z-VAD-fmk, a broad-range caspase inhibitor, or Ac-DEVD-CHO, a caspase-3 inhibitor. In addition to the caspase-3 activation, capsaicin also induced cytochrome c release and decrease in Bcl-2 protein expression with no changes in the level of Bax. Furthermore, capsaicin at the concentration of inducing apoptosis also markedly reduced the level of reactive oxygen species and lipid peroxidation, implying that capsaicin may enhance the antitumor effect of BCG in bladder cancer treatment. These results further suggest that capsaicin may be a valuable intravesical chemotherapeutic agent for bladder cancers.

Numerical Study of Heat Transfer Associated with Droplet Impact (액적 충돌에 동반된 열전달에 관한 수치적 연구)

  • Kim, Sung-Il;Son, Gi-Hun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.9
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    • pp.1093-1100
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    • 2004
  • Numerical analysis of the heat transfer associated with droplet impact on a hot solid surface is performed by solving the equations governing conservation of mass, momentum and energy in the liquid and gas phases. The deformed droplet shape is tracked by a level set method which is modified to achieve volume conservation and to include the effect of contact angle at the wall. The numerical method is validated through the calculations for the cases reported in the literature. Based on the numerical results, the heat transfer rate is found to depend strongly on the droplet spread radius. Decreased advancing/receding contact angles enlarge the splat radius and in turn enhance the wall heat flux. The effect of impact velocity on the droplet spread is reduced as the droplet size decreases. Also, droplet atomization is observed to significantly enhance the heat transfer rate and the effect is pronounced for a smaller size of droplet. An existing model equation to predict the maximum spread radius is improved for application to a micro droplet.

Stimulatory Effect of N-acetylcysteine on Odontoblastic Differentiation

  • Jun, Ji-Hae;Lee, Hye-Lim;Baek, Jeong-Hwa
    • International Journal of Oral Biology
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    • v.33 no.4
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    • pp.187-195
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    • 2008
  • Reparative dentine formation requires newly differentiated odontoblast-like cells. Therefore, identification of the molecule that stimulates the odontogenic differentiation of precursor cells in the tooth pulp will be helpful for the development of strategies to repair damaged pulp. In this study, we examined the effect of N-acetylcysteine (NAC) on the odontogenic differentiation of MDPC-23 cells, a mouse odontoblast-like cell line derived from dental papilla, and primary cultured rat dental papilla cells (RDPCs). NAC (1-30 mM) suppressed production of reactive oxygen species in MDPC-23 cells in a dose-dependent manner. Although 5 to 20 mM NAC did not alter MDPC-23 cell proliferation, 1 or 30 mM NAC significantly inhibited it. NAC enhanced mineralized nodule formation and the expression of several odontoblast differentiation-associated genes in both RDPCs and MDPC-23. This NAC stimulatory effect was significant, even at concentrations lower than 1 mM. However, NAC did not stimulate expression of bone morphogenetic protein-2, -4, or -7, which are known to enhance odontogenic differentiation. Since reactive oxygen species are also involved in the pulp toxicity of resin-based restorative materials, these results suggest that NAC may be a promising candidate for supplementation of dental restorative materials in order to enhance reparative dentine formation.

Induction and Chatacterization of pKM101 Mutants in Salmonella typhimurium (Salmonella typhimurium내로의 pKM101 돌연변이체의 유도와 그 특성에 관한 연구)

  • 백형석;강수형;이세영
    • Korean Journal of Microbiology
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    • v.20 no.2
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    • pp.89-97
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    • 1982
  • Mutants of plasmid pKM101 modified to enhance mutagenesis were induced and characterized in Salmonella typhimurium. The pKM101 mutant plasmid were transferred normally and stably maintained in cells. They had modified in their ability (i) to enhance the reversion of both point and frameshift mutations, (ii) to protect the cell against UV-irradiation and chemical mutagen treatment, (iii) of ampicillin resistance. A similar modification in enhancement of reversion was also observed in a $uvrB^-$ strains. These results indicated that mutator effect of pKM101 was coded by one plasmid gene.

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Experimental and numerical study on the dynamic behavior of a semi-active impact damper

  • Zheng Lu;Mengyao Zhou;Jiawei Zhang;Zhikuang Huang;Sami F. Masri
    • Smart Structures and Systems
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    • v.31 no.5
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    • pp.455-467
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    • 2023
  • Impact damper is a passive damping system that controls undesirable vibration with mass block impacting with stops fixed to the excited structure, introducing momentum exchange and energy dissipation. However, harmful momentum exchange may occur in the random excitation increasing structural response. Based on the mechanism of impact damping system, a semi-active impact damper (SAID) with controllable impact timing as well as a semi-active control strategy is proposed to enhance the seismic performance of engineering structures in this paper. Comparative experimental studies were conducted to investigate the damping performances of the passive impact damper and SAID. The extreme working conditions for SAID were also discussed and approaches to enhance the damping effect under high-intensity excitations were proposed. A numerical simulation model of SAID attached to a frame structure was established to further explore the damping mechanism. The experimental and numerical results show that the SAID has better control effect than the traditional passive impact damper and can effectively broaden the damping frequency band. The parametric studies illustrate the mass ratio and impact damping ratio of SAID can significantly influence the vibration control effect by affecting the impact force.

Effect of KORAIL Tour Conductors' Emotional Labor on Customer Orientation: Moderating Effect of Perceived Organizational Support (철도여행인솔자의 감정노동이 고객지향성에 미치는 영향 - 조직지원인식의 조절효과 -)

  • Hur, Chan-Young;Kim, Tae-Seong
    • Journal of the Korean Society for Railway
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    • v.17 no.4
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    • pp.289-296
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    • 2014
  • This study analyzes, based on survey of the behavior of 288 railroad tour conductors. how deep acting and surface acting, which were both classified as emotional labor, influence customer orientation. It also analyzes the moderating effect of POS (perceived organizational support) on emotional labor and customer orientation. The following are the summarized results of the analysis. First, railroad tour conductors' deep acting has a positive influence on customer orientation. And surface acting has a negative effect on it. Second, after the moderating effect of POS has been studied, it is found that POS does not appear to have a moderating effect on customer orientation of deep acting but does appear to have a moderating effect on customer orientation of surface acting. In conclusion, this study implies that it is important, to railroad tour conductors, that organizational level support enhance customer orientation; it is also important to manage railroad tour conductors' emotions in order to enhance customer orientation.